Amikacin assay: correlation between rapid bioassay, enzyme immuno-assay (EMIT) and fluoro-immuno-assay (FIA).

Abstract:

:Three methods (rapid bioassay, enzyme immunoassay and fluoroimmunoassay) for the determination of amikacin level in serum are compared. The statistical analysis of the results show correlation coefficients equal to 0.967 (EMIT versus FIA), 0.970 (bioassay versus FIA) and 0.983 (bioassay versus EMIT). The three methods are acceptable for routine clinical use. The enzyme immunoassay adapted on a centrifugal analyzer appears to be a method of choice for laboratories with a large workload. However, the rapid bioassay described in this paper remains adequate for laboratories testing 5 to 10 sera per day.

journal_name

Ann Biol Clin (Paris)

authors

Damien JM,Courcol RJ,Houdret N,Lhermitte M,Martin GR

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

217-20

issue

3

eissn

0003-3898

issn

1950-6112

journal_volume

42

pub_type

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