[Descriptive and comparative study of technical methods used for the detection of antinuclear antibodies].

Abstract:

:There has been rapid progress in techniques for the detection of antinuclear antibodies. The methods most widely used at present are indirect immunofluorescence, Ouchterlony double immunodiffusion, passive haemagglutination and the Farr test. Antinuclear antibodies recognise several antigens. With a few exceptions, indigenous DNA is specific to DLE and is seen in more than 80 p. cent of patients. Other antibodies are less constant but equally specific: anti-Sm in DLE, antinucleolus in scleroderma. By contrast, the antibodies present in Sjögren's syndrome and anti-ENP would not seem to be specific to any single disease and the quite widely found anti-DNA is of little diagnostic interest.

journal_name

Ann Biol Clin (Paris)

authors

Abuaf N

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

65-74

issue

2

eissn

0003-3898

issn

1950-6112

journal_volume

40

pub_type

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