Birefringent periodicities in amphibian rod outer segments.

abstract：PURPOSE:To assess the effect of aging on optical quality in a normal population. METHODS:We prospectively examined 100 normal eyes of 100 healthy volunteers (50 men, 50 women; ages, 20-69 years; mean age ± standard deviation, 44.6 ± 15.5 years). We quantitatively assessed the values of MTF cutoff frequency, Strehl rat...

journal_title：Current eye research

authors： Kamiya K,Umeda K,Kobashi H,Shimizu K,Kawamorita T,Uozato H

更新日期：2012-10-01 00:00:00

abstract：:It has been hypothesized that an activator of Ca-ATPase co-exists with Ca-ATPase in the mouse lens. Though the Ca-ATPase activity could be measured from mouse lens homogenate, its activity could not be determined in individual soluble and insoluble fractions. The Ca-ATPase activity, however, could be detected when an ...

journal_title：Current eye research

authors： Iwata S,Shirasawa E,Takehana M

更新日期：1984-05-01 00:00:00

abstract：AIMS:To elucidate the intramuscular distribution and branching patterns of the abducens nerve in the lateral rectus (LR) muscle so as to provide anatomical confirmation of the presence of compartmentalization, including for use in clinical applications such as botulinum toxin injections. METHODS:Thirty whole-mount hum...

journal_title：Current eye research

authors： Shin HJ,Lee SH,Shin KJ,Koh KS,Song WC

更新日期：2018-06-01 00:00:00

abstract：:Purpose: To determine the prevalence of posterior segment manifestations among consecutive patients with pathological myopia attending our University Hospital general ophthalmology clinic and their association with age, refractive error, axial length and each other. Methods: Patients diagnosed with pathological myopia...

journal_title：Current eye research

authors： Elnahry AG,Khafagy MM,Esmat SM,Mortada HA

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To determine the relative expression of metallothionein isoforms and their differential induction by oxidative stress in cultured RPE cells and to localize the isoforms in the human chorioretinal complex. METHODS:Total RNA was isolated from cultured human retinal pigment epithelial cells using TRI-Reagent. An ...

journal_title：Current eye research

authors： Tate DJ,Miceli MV,Newsome DA

更新日期：2002-01-01 00:00:00

abstract：:Systemically administered fluorescein is converted to fluorescein glucuronide. The conjugate is fluorescent and interferes with the measurement of fluorescein in the anterior chamber. Carboxyfluorescein is a hydrophilic derivative of fluorescein. In the rabbit, carboxyfluorescein is not converted as readily to a fluor...

journal_title：Current eye research

authors： Neault TR,McLaren JW,Brubaker JH,Brubaker RF

更新日期：1986-05-01 00:00:00

abstract：:5-Fluorouracil (5-FU) and Mitomycin C (MMC) are used as adjunct chemotherapy during glaucoma filtering surgery to suppress conjunctival fibroblast proliferation. Since part of these agents may gain access to the anterior chamber and cause cytotoxicity to the corneal endothelium we set up an in vitro system to establis...

journal_title：Current eye research

authors： Nuyts RM,Pels E,Greve EL

更新日期：1992-06-01 00:00:00

abstract：:Two proteins, with molecular weights of 49 (CP49) and 115 kDa (CP115) as judged by SDS PAGE, have been shown by immunocytochemistry to be components of the beaded filament, a cytoskeletal structure thus far demonstrated only in the lens fiber cell. We have used antibodies reactive with CP49 to screen a mouse lens cDNA...

journal_title：Current eye research

authors： Hess JF,Casselman JT,FitzGerald PG

更新日期：1993-01-01 00:00:00

abstract：:Purpose: The purpose of this study is to present the study design and one month's preliminary results of a 2-year randomized trial, Combined Atropine with Orthokeratology (AOK), for myopia control study. Methods: Children aged 6 to <11 years and with 1.00-4.00 D myopia were randomly assigned to AOK group or ortho-k al...

journal_title：Current eye research

authors： Tan Q,Ng AL,Cheng GP,Woo VC,Cho P

更新日期：2019-06-01 00:00:00

abstract：:The lacrimal gland stores retinyl esters which are synthesized by the enzyme acyl CoA:retinyl acyl transferase. Retinol is released from retinyl ester reserves by retinyl ester hydrolase (REH). Since the lacrimal gland secretes retinol, this gland should also contain this enzyme. To identify bile salt-dependent REH ac...

journal_title：Current eye research

authors： Bernal DL,Ubels JL

更新日期：1992-09-01 00:00:00

abstract：:A reduced nicotinamide adenine dinucleotide phosphate (NAD(P)H)-dependent hydrogen peroxide-generating activity of rat ocular tissue was investigated cytochemically utilizing the cerium method. NADPH or NADH oxidation resulted in electron-dense fine granular deposits on the corneal epithelial and endothelial plasma me...

journal_title：Current eye research

authors： Atalla LR,Sevanian A,Rao NA

更新日期：1988-09-01 00:00:00

abstract：PURPOSE:To evaluate the feasibility of retinal vein bypass surgery for induced branch retinal-vein occlusion (BRVO) in the living porcine eye. METHODS:Fifteen minipigs were used in the study. Seven days before vascular surgery, hyaluronidase and plasmin were intravitreally injected for induction of posterior vitreous ...

journal_title：Current eye research

authors： Shen LJ,Chen YQ,Cheng D,Zhang C,Jiang L,Hong M,Kang QY

更新日期：2016-01-01 00:00:00

abstract：:The basement membrane of the crystalline lens of the diabetic rat was found to have a similar elasticity modulus at high stress to that of normal membrane. However, at low stress and extension Young's modulus of elasticity was 0.36 (Mean) +/- 0.15 (SD) X 10(6) Nm-2 and about 30 per cent lower than that of normal membr...

journal_title：Current eye research

authors： Hayes BP,Fisher RF

更新日期：1981-01-01 00:00:00

abstract：PURPOSE:Folic acid (FA) is an essential nutrient for normal embryonic development. FA deficiency (FAD) in maternal diet increases the risk of several defects among the progeny, especially, neural tube defects. The eye begins its development from the neural tube; however, the relationship between FAD and ocular developm...

journal_title：Current eye research

authors： Sijilmassi O,López-Alonso JM,Del Río Sevilla A,Murillo González J,Barrio Asensio MDC

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:Recent studies have shown that the levels of interleukin (IL)-1beta, IL-6 and IL-8 are associated with the severity of infectious diseases. The purpose of this study was to investigate whether IL-1beta regulates the expression of IL-6 and IL-8 in human corneal epithelial cells during Pseudomonas aeruginosa colo...

journal_title：Current eye research

authors： Xue ML,Zhu H,Willcox M,Wakefield D,Lloyd A,Thakur A

更新日期：2001-12-01 00:00:00

abstract：:As it is known that chlorpromazine (CPZ) can bind to melanins as well as cause ocular phototoxicity, we investigated the cytotoxic effects of UV-visible irradiation of melanotic and amelanotic retinal pigment epithelial (RPE) cells in the presence of CPZ. At low concentrations (5 micrograms/ml) of CPZ a photosensitiza...

journal_title：Current eye research

authors： Persad S,Menon IA,Basu PK,Carre F

更新日期：1988-01-01 00:00:00

abstract：:Purpose: To determine the refractive astigmatism following toric intraocular lens (tIOL) implantation without consideration of posterior keratometric astigmatism with a conventional tIOL calculator for eyes with low keratometric astigmatism (0.75D to 2.5D) and to theoretically compare the outcomes with predicted refra...

journal_title：Current eye research

authors： Nanavaty MA,Teeluck K,Bardan AS,Bedi KK,Ali S

更新日期：2019-12-01 00:00:00

abstract：:The distribution of a steroid antagonist, RU486, that is known to reduce rabbit intraocular pressure has been examined in the eye. On an equal tissue weight basis, the corneal epithelium is the site of maximal absorption followed by conjunctival tissues (bulbar and palpebral) and the rest of the cornea. Aqueous humor ...

journal_title：Current eye research

authors： Cheeks L,Green K

更新日期：1986-09-01 00:00:00

abstract：:Purpose/Aim: To assess the changes in anterior eye segment biometrics and intraocular pressure during and after wearing swimming goggles.Materials and methods: Anterior segment biometry and intraocular pressure were assessed in 20 healthy young adults (22.2 ± 4.7 years) during the wearing of a drilled swimming goggle....

journal_title：Current eye research

authors： Jiménez R,Molina R,García JA,Redondo B,Vera J

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:To examine whether transforming growth factor-beta 2 (TGF-beta 2) induces the expression of alpha-smooth muscle actin (SMA), a biochemical marker of myofibroblasts, in cultured bovine retinal pigment epithelial (RPE) cells. METHODS:Bovine RPE cells were cultured in F-12 nutrient mixture supplemented with 5% fe...

journal_title：Current eye research

authors： Kurosaka D,Muraki Y,Inoue M,Katsura H

更新日期：1996-11-01 00:00:00

abstract：:Focused ultrasound concentrates a large amount of ultrasonic energy into a small focal zone. We have used new techniques to develop a transducer that creates intracorneal, thermally induced lesions in rabbit eyes in vitro. Histologic study shows that these lesions are confined to the stroma and that the procedure caus...

journal_title：Current eye research

authors： Mark DB,Beuerman R

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:There is a clinical need for biomimetic corneas that are as effective, preferably superior, to cadaveric donor tissue. Decellularized tissues are advantageous compared to synthetic or semi-synthetic engineered tissues in that the native matrix ultrastructure and intrinsic biological cues including growth fac...

journal_title：Current eye research

authors： Wilson SL,Sidney LE,Dunphy SE,Dua HS,Hopkinson A

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To assess the rate of achieving optimal metabolic control among subjects with type 2 diabetes, to elucidate the influence of suboptimal control on diabetic retinopathy (DR) and to analyze the risk factors associated with DR in the subjects with suboptimal control. MATERIAL AND METHODS:A population-based, cross...

journal_title：Current eye research

authors： Raman R,Gupta A,Kulothungan V,Sharma T

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:To evaluate "in vivo" the effect of topical travoprost on the central corneal thickness (CCT) of rabbit eyes, and the changes in the CCT after acute increases of intraocular pressure (IOP) in these eyes. MATERIALS AND METHODS:This is an interventional, prospective, case-control, masked study. Topical travopros...

journal_title：Current eye research

authors： Bolívar G,Teus M,Arranz-Marquez E

更新日期：2011-11-01 00:00:00

abstract：:Samples of aqueous humor from rabbits and humans were examined for growth effects on subconfluent monolayer fibroblast cultures from ocular and extraocular tissues. At a concentration of 20% aqueous by medium volume, both homologous and heterologous aqueous stimulated DNA synthesis in fibroblasts from both species. Th...

journal_title：Current eye research

authors： Burke J,Foster S,Herschler J

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:To examine the effects of nitric oxide synthase (NOS) inhibitors on intraocular pressure (IOP) and ocular inflammation following laser irradiation of the rabbit iris, and to investigate the involvement of nitric oxide (NO). METHODS:Thirty min after the intravenous administration of a nonselective inhibitor of ...

journal_title：Current eye research

authors： Taniguchi T,Kawakami H,Sawada A,Iwaki M,Tsuji A,Sugiyama K,Kitazawa Y

更新日期：1998-03-01 00:00:00

abstract：PURPOSE:Acyclovir has been shown to be effective in preventing recurrent herpes simplex virus lesions of the genitalia and oral labia. The purpose of the current study was to determine the effect of acyclovir on the appearance of infectious virus in the peripheral nervous system and in an end organ, the eye. MATERIALS...

journal_title：Current eye research

authors： Gebhardt BM,Kaufman HE,Hill JM

更新日期：2004-08-01 00:00:00

abstract：:The cell content of the precorneal tears of eight subjects was sampled following overnight wear of a contact lens in one eye. This was compared with morning samples taken from the other eye, and afternoon samples taken several days later from both eyes. In the morning the median number of desquamated epithelial cells ...

journal_title：Current eye research

authors： Wilson G,O'Leary DJ,Holden BA

更新日期：1989-04-01 00:00:00

abstract：PURPOSE:The present study was conducted to develop and characterize a functional primary culture of pigmented rabbit conjunctival epithelial cells on permeable support exhibiting tight barrier properties. METHODS:Conjunctival epithelial cells were isolated by 0.2% protease treatment, cultured at 0.5-1.8 x 10(6) cells/...

journal_title：Current eye research

authors： Saha P,Kim KJ,Lee VH

更新日期：1996-12-01 00:00:00

abstract：:The effects of light damage were studied in four inbred strains of albino rats, Fischer (F344), Lewis (L), Wistar (W), and Buffalo (BUF). Thirty-five-day-old rats (3 from each strain) were kept in cyclic light for two weeks, after which they were exposed to constant fluorescent light (180-190 foot-candles, 490-580 nm)...

journal_title：Current eye research

authors： Borges JM,Edward DP,Tso MO

更新日期：1990-08-01 00:00:00