Prevalence of hepatitis C virus and HIV infection among injection drug users in two Mexican cities bordering the U.S.

Abstract:

OBJECTIVE:To estimate the prevalence of the hepatitis C virus (HCV) and HIV infection and associated risk behaviors among injection drug users (IDUs) in two northern Mexican cities. MATERIAL AND METHODS:Between February and April 2005, IDUs were recruited in Tijuana (N=222) and Ciudad Juarez (N=206) using respondent-driven sampling (RDS), a chain referral sampling approach. Interviewer-administered questionnaires assessed drug-using behaviors during the prior six months. Venous blood was collected for immunoassays to detect HIV and HCV antibodies. For HIV, Western blot or immunofluorescence assay was used for confirmatory testing. Final HCV antibody prevalence was estimated using RDS adjustments. RESULTS:Overall, HCV and HIV prevalence was 96.0% and 2.8%, respectively, and was similar in both cities. Most IDUs (87.5%) reported passing on their used injection equipment to others, and 85.9% had received used equipment from others. CONCLUSIONS:HIV prevalence was relatively high given the prevalence of HIV in the general population, and HCV prevalence was extremely high among IDUs in Tijuana and Ciudad Juarez. Frequent sharing practices indicate a high potential for continued transmission for both infections. HCV counseling and testing for IDUs in Mexico and interventions to reduce sharing of injection equipment are needed.

journal_name

Salud Publica Mex

journal_title

Salud publica de Mexico

authors

White EF,Garfein RS,Brouwer KC,Lozada R,Ramos R,Firestone-Cruz M,Pérez SG,Magis-Rodríguez C,Conde-Glez CJ,Strathdee SA

doi

10.1590/s0036-36342007000300001

subject

Has Abstract

pub_date

2007-05-01 00:00:00

pages

165-72

issue

3

eissn

0036-3634

issn

1606-7916

pii

S0036-36342007000300001

journal_volume

49

pub_type

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