Protective effects of cardioplegia on diastolic function of hypertrophied rat hearts after hypothermic ischaemic arrest.

abstract：AIMS:Anecdotal observations suggest that sub-clinical electrophysiological manifestations of arrhythmogenic right ventricular cardiomyopathy (ARVC) develop before detectable structural changes ensue on cardiac imaging. To test this hypothesis, we investigated a murine model with conditional cardiac genetic deletion of ...

journal_title：European heart journal

authors： Gomes J,Finlay M,Ahmed AK,Ciaccio EJ,Asimaki A,Saffitz JE,Quarta G,Nobles M,Syrris P,Chaubey S,McKenna WJ,Tinker A,Lambiase PD

更新日期：2012-08-01 00:00:00

abstract：:Adenosine test (supine administration of a 20 mg intravenous bolus with electrocardiographic and blood pressure monitoring) has been endorsed by the European Society of Cardiology guidelines on syncope management as an 'experimental' test in the diagnosis of unexplained syncope. The test is quick and cheap, but there ...

journal_title：European heart journal

authors： Parry SW,Nath S,Bourke JP,Bexton RS,Kenny RA

更新日期：2006-06-01 00:00:00

abstract：:A 37-year-old man sustained occlusion of the right coronary artery after a bicycle accident with blunt chest trauma over the left scapula. Acute coronary angiography was performed because of chest pain and ST-segment elevation. Despite surgically successful acute revascularization the patient developed a transmural in...

journal_title：European heart journal

authors： Gustavsson CG,Albrechtsson U,Forslind K,Ståhl E,White T

更新日期：1992-01-01 00:00:00

abstract：AIMS:We addressed a potential mechanism of myocardial dysfunction following coronary microembolization at the level of myofibrillar proteins. METHODS AND RESULTS:Anaesthetized pigs underwent intracoronary infusion of microspheres. After 6 h, the microembolized areas (MEA) had decreased systolic wall thickening to 38 +...

journal_title：European heart journal

authors： Canton M,Skyschally A,Menabò R,Boengler K,Gres P,Schulz R,Haude M,Erbel R,Di Lisa F,Heusch G

更新日期：2006-04-01 00:00:00

abstract：:Left ventricular (LV) filling as assessed by Doppler transmitral flow velocity measurements was studied in 20 male patients with coronary artery disease (CAD) and in 18 normal individuals. Stroke volume, blood pressure and heart rate in the two groups were not significantly different. Compared to normals, the ratio be...

journal_title：European heart journal

authors： Myreng Y,Ihlen H,Nitter-Hauge S

更新日期：1988-11-01 00:00:00

abstract：AIMS:Coronary artery dissections are common findings following percutaneous transluminal coronary angioplasty and occur with an incidence of approximately 20% to 40%. The purpose of this study was to evaluate the impact of intravascular ultrasound for the prediction of severe dissections by pre-interventional analysis ...

journal_title：European heart journal

authors： Athanasiadis A,Haase KK,Wullen B,Treusch AW,Mahrholdt H,Voelker W,Baumbach A,Oberhoff M,Karsch KR

更新日期：1998-06-01 00:00:00

abstract：AIMS:Patients with acute coronary syndrome (ACS) in the Myocardial Ischaemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study had diminished cardiovascular events after 16 weeks of treatment of atorvastatin 80 mg daily. We determined whether plasma lipoproteins at baseline and then at 6 weeks after randomi...

journal_title：European heart journal

authors： Olsson AG,Schwartz GG,Szarek M,Sasiela WJ,Ezekowitz MD,Ganz P,Oliver MF,Waters D,Zeiher A

更新日期：2005-05-01 00:00:00

abstract：AIMS:No-reflow after a primary percutaneous coronary intervention (PCI) is associated with a high incidence of left ventricular (LV) failure and a poor prognosis. Endothelin-1 (ET-1) is a potent endothelium-derived vasoconstrictor peptide and an important modulator of neutrophil function. Elevated systemic ET-1 levels ...

journal_title：European heart journal

authors： Niccoli G,Lanza GA,Shaw S,Romagnoli E,Gioia D,Burzotta F,Trani C,Mazzari MA,Mongiardo R,De Vita M,Rebuzzi AG,Lüscher TF,Crea F

更新日期：2006-08-01 00:00:00

abstract：:The steady state plasma concentrations of the two platelet-specific proteins beta-thromboglobulin (BTG) and platelet factor 4 (PF4) were determined in two groups of females: 36 acute myocardial infarction (AMI) survivors, and 38 age-matched control subjects. For the AMI patients the mean BTG and PF4 values were 57 +/-...

journal_title：European heart journal

authors： Kutti J,Johansson S,Eriksson KA,Sigvaldason A,Vedin A,Wadenvik H,Wilhelmsson C

更新日期：1983-05-01 00:00:00

abstract：:The reperfusion era has dramatically and irrevocably transformed the management of ST-segment elevation myocardial infarction (STEMI). For the patient treated with fibrinolysis as the initial reperfusion strategy, subsequent options which are the subject of some controversy and the focus of this review are (i) facilit...

journal_title：European heart journal

authors： Kiernan TJ,Ting HH,Gersh BJ

更新日期：2007-07-01 00:00:00

abstract：:A total of 546 patients with severe aortic stenosis (AS) were retrospectively reviewed to assess the efficacy of percutaneous transluminal valvuloplasty (PTV) and valve replacement (VR). Of these, 490 underwent VR between 1968 and 1986 (mean age 62 +/- 12 years, 71.7% were in NYHA class III or IV), 68.8% received mech...

journal_title：European heart journal

authors： Acar J,Vahanian A,Slama M,Cormier B,Michel PL,Luxereau P,Farah E,Leborgne O,Dermine P

更新日期：1988-04-01 00:00:00

abstract：:A double-blind, placebo-controlled trial comparing the antiarrhythmic effects of lidocaine (given intravenously as a bolus injection of 100 mg followed by an infusion of 2 mg min-1) and propafenone (given as a bolus of 105 mg followed by 300 mg orally every 8 h) was conducted in the first 24 h following acute myocardi...

journal_title：European heart journal

authors： Touboul P,Moleur P,Mathieu MP,Vrancea F,Ferry S,Kirkorian G,Atallah G,Marchand A,Stahl C,Zoheir F

更新日期：1988-11-01 00:00:00

abstract：:The slope and pressure half-time of the aortic regurgitant velocity spectrum have been used as non-invasive markers of regurgitant severity. Recent in vitro and theoretical work, however, has suggested a confounding effect of systemic vascular resistance and left ventricular compliance on these parameters. To study th...

journal_title：European heart journal

authors： Griffin BP,Flachskampf FA,Reimold SC,Lee RT,Thomas JD

更新日期：1994-05-01 00:00:00

abstract：AIMS:This study investigated whether sedentary behaviour and different activity levels have an independent association with carotid intima-media thickness (IMT) and with the 3-year IMT progression in different carotid segments. METHODS AND RESULTS:The study population included 614 healthy men and women (mean age = 44 ...

journal_title：European heart journal

authors： Kozàkovà M,Palombo C,Morizzo C,Nolan JJ,Konrad T,Balkau B,RISC Investigators.

更新日期：2010-06-01 00:00:00

abstract：:The resting and exertional haemodynamic effects of acute and chronic discontinuous (one tablet every 6 h) treatment with 5 mg of buccal nitroglycerin (BN) have been assessed in nine postinfarction heart failure patients. At rest, pulmonary artery (PAP), pulmonary wedge (PWP), and right atrial pressures (RAP) were redu...

journal_title：European heart journal

authors： Opasich C,Riccardi G,Febo O,Tramarin R,Lepore AM,Luca C,Cobelli F,Specchia G

更新日期：1988-03-01 00:00:00

abstract：AIMS:Surgery in patients with infective endocarditis (IE) can be elective (upon completion of antibiotic treatment) or urgent (before antibiotic treatment has ended) when the clinical course is unfavourable. However, urgent surgery for left-sided endocarditis is associated with high mortality. The aims of this study we...

journal_title：European heart journal

authors： Revilla A,López J,Vilacosta I,Villacorta E,Rollán MJ,Echevarría JR,Carrascal Y,Di Stefano S,Fulquet E,Rodríguez E,Fiz L,San Román JA

更新日期：2007-01-01 00:00:00

abstract：:This study analyses the immediate outcome and the risk of recurrent restenosis in patients who, at the time of repeat coronary angioplasty for a first restenosis, had unstable (n = 50), 19%) or stable (n = 218, 81%) angina. Successful angioplasty was accomplished in 250 (93%) patients, 222 (89%) of whom had follow-up ...

journal_title：European heart journal

authors： Bauters C,Lablanche JM,McFadden EP,Leroy F,Bertrand ME

更新日期：1993-02-01 00:00:00

abstract：AIMS:In acute coronary syndromes (ACS), the optimal revascularization strategy for unprotected left main coronary disease (ULMCD) has been little studied. The objectives of the present study were to describe the practice of ULMCD revascularization in ACS patients and its evolution over an 8-year period, analyse the pro...

journal_title：European heart journal

authors： Montalescot G,Brieger D,Eagle KA,Anderson FA Jr,FitzGerald G,Lee MS,Steg PG,Avezum A,Goodman SG,Gore JM,GRACE Investigators.

更新日期：2009-10-01 00:00:00

abstract：:Treatment of 8 hypertensive elderly subjects with atenolol or with labetalol did not affect exercise performance, except after the development of circulatory congestion in 1 patient. Treatment with beta blockers did not alter the response to an exercise training programme in 15 elderly patients with ischaemic heart di...

journal_title：European heart journal

authors： Fagard R,Reybrouck T,Vanhees L,Cattaert A,Vanmeenen T,Grauwels R,Amery A

更新日期：1984-11-01 00:00:00

abstract：:The effects of xamoterol 0.2 mg kg-1 i.v. and placebo on left ventricular function at rest and on exercise were compared in patients with left ventricular dysfunction due to ischaemic heart disease. Improvements were seen in systolic and diastolic function at rest, and at up to 50% of maximal exercise, without evidenc...

journal_title：European heart journal

authors： de Feyter PJ,Serruys PW

更新日期：1990-04-01 00:00:00

abstract：AIMS:To evaluate the association between occupational and leisure-time physical activity (PA), ownership of goods promoting sedentary behaviour, and the risk of myocardial infarction (MI) in different socio-economic populations of the world. Studies in developed countries have found low PA as a risk factor for cardiova...

journal_title：European heart journal

authors： Held C,Iqbal R,Lear SA,Rosengren A,Islam S,Mathew J,Yusuf S

更新日期：2012-02-01 00:00:00

abstract：AIMS:Emerging evidence indicates that nuclear receptors play a critical regulatory role in cardiovascular physiology/pathology. Recently, farnesoid-X-receptor (FXR), a member of the metabolic nuclear receptor superfamily, has been demonstrated to be expressed in vascular cells, with important roles in vascular physiolo...

journal_title：European heart journal

authors： Pu J,Yuan A,Shan P,Gao E,Wang X,Wang Y,Lau WB,Koch W,Ma XL,He B

更新日期：2013-06-01 00:00:00

abstract：:Intracranial mycotic aneurysms (IMA) occur in 1-3% of all infective endocarditis. Although spontaneous resolution was evidenced on serial angiograms in many asymptomatic cases, the prognosis, if they rupture, is reported to be worse and partly contingent on the therapeutic approach. Among 12 patients (six acute and si...

journal_title：European heart journal

authors： Monsuez JJ,Vittecoq D,Rosenbaum A,Goujon C,Wolff M,Witchitz S,Modai J

更新日期：1989-09-01 00:00:00

abstract：UNLABELLED:Peripheral vessels provide a useful in vivo haemodynamic model allowing evaluation of local intravascular fluid dynamics. Velocity measurements using a 0.018 inch Doppler-tipped angioplasty guidewire, quantitative angiography and laboratory data were gathered from 45 patients with a total of 48 percutaneous ...

journal_title：European heart journal

authors： Wellnhofer E,Biamino G,Sauer HU,Trebeljahr A,Stalke J,Ragg C,Oswald H,Gotze S,Fleck E,Felix R

更新日期：1995-10-01 00:00:00

abstract：:The generation of abnormal gradients between the apical cavity and the subaortic valvular region of the left ventricle in patients with hypertrophic cardiomyopathy (HCM) has traditionally been equated to a dynamic obstruction to left ventricular outflow. To examine this concept in more detail, left ventricular ejectio...

journal_title：European heart journal

authors： Murgo JP,Alter BR,Dorethy JF,Altobelli SA,Craig WE,McGranahan GM Jr

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:Maximal hyperaemia is paramount in the diagnosis of patients with coronary artery disease. However in these patients, enhanced alpha-adrenergic microvascular vasoconstriction may preclude adenosine to induce maximal hyperaemia. AIM:To assess the presence and the clinical relevance of residual microvascular ...

journal_title：European heart journal

authors： Barbato E,Bartunek J,Aarnoudse W,Vanderheyden M,Staelens F,Wijns W,Heyndrickx GR,Pijls NH,De Bruyne B

更新日期：2004-11-01 00:00:00

abstract：AIMS:The study aimed to compare the addition of felodipine to metoprolol, and of the replacement of metoprolol by felodipine, with continuation of metoprolol, in patients with angina pectoris despite optimal beta-blockade. METHODS AND RESULTS:The study was double-blind, parallel, randomized and controlled, and compris...

journal_title：European heart journal

authors： Dunselman P,Liem AH,Verdel G,Kragten H,Bosma A,Bernink P

更新日期：1997-11-01 00:00:00

abstract：:The survival rate of 2256 patients with pacemakers was analyzed. Patients paced for Adams-Stokes equivalents (e.g. dizziness) showed a significantly better survival rate than did patients with pacemakers implanted for Adam-Stokes attacks or heart failure (P less than 0.0001). The estimated survival of the latter two g...

journal_title：European heart journal

authors： Müller C,Cernin J,Glogar D,Laczkovics A,Mayr H,Scheibelhofer W,Schmidinger H,Schuster E,Sedlacek K,Kaliman J

更新日期：1988-09-01 00:00:00

abstract：:Chronic increases in haemodynamic load modify the expression of cardiac genes, leading to a new phenotype better adapted to the new functional demand. Several mechanisms such as the global activation of genes, the modulation of single genes and/or differential expression of multigene families may account for these mod...

journal_title：European heart journal

authors： Samuel JL,Dubus I,Contard F,Schwartz K,Rappaport L

更新日期：1990-11-01 00:00:00

abstract：AIMS:Obesity is a recognized risk factor for atrial fibrillation (AF), partly because of the association between body mass index (BMI) and atrial volume. We aimed to determine whether other factors relating to body size were related to AF. METHODS AND RESULTS:Data were derived from a random population sample of 6903 m...

journal_title：European heart journal

authors： Rosengren A,Hauptman PJ,Lappas G,Olsson L,Wilhelmsen L,Swedberg K

更新日期：2009-05-01 00:00:00