Germ cells: the eternal link between generations.

Abstract:

:The pluripotent epiblast cells in the early embryo are destined to form both the somatic cells and primordial germ cells. In the few cells that undergo specification to establish the germ cell lineage, there is repression of the somatic programme. Recent evidence shows that, Blimp1, a known transcriptional repressor with a SET/PR domain, is crucial for the specification of primordial germ cells (PGC). Blimp1 has the role, at least in part, of suppressing the somatic programme.

journal_name

C R Biol

journal_title

Comptes rendus biologies

authors

Surani MA

doi

10.1016/j.crvi.2007.03.009

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

474-8

issue

6-7

eissn

1631-0691

issn

1768-3238

pii

S1631-0691(07)00142-4

journal_volume

330

pub_type

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