Abstract：
:The development of molecular biology placed in the foreground a mechanistic and deterministic conception of the functioning of macromolecules. In this article, I show that this conception was neither obvious, nor necessary. Taking Jacques Monod as a case study, I detail the way he gradually came loose from a statistical understanding of determinism to finally support a mechanistic understanding. The reasons of the choice made by Monod at the beginning of the 1950s can be understood only in the light of the general theoretical schema supported by the concept of mechanistic determinism. This schema articulates three fundamental notions for Monod, namely that of the rigidity of the sequence of the genetic program, that of the intrinsic stability of macromolecules (DNA and proteins), and that of the specificity of molecular interactions.
journal_name
C R Bioljournal_title
Comptes rendus biologiesauthors
Loison Ldoi
10.1016/j.crvi.2015.03.008subject
Has Abstractpub_date
2015-06-01 00:00:00pages
391-7issue
6eissn
1631-0691issn
1768-3238pii
S1631-0691(15)00086-4journal_volume
338pub_type
历史文章,杂志文章abstract：:A new remarkable species belonging to the genus Ananteris Thorell, 1891 (Buthidae) is described from the Mitaraka Massif in French Guiana, a site located near the borders of French Guiana, Brazil, and Suriname. The description of this new species brings further evidence about the biogeographic patterns of distribution...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2016.04.002
更新日期：2016-05-01 00:00:00
abstract：PURPOSE:The aim of this study was to monitor in vivo with low field MRI growth of a murine orthotopic glioma model following a suicide gene therapy. METHODS:The gene therapy consisted in the stereotactic injection in the mice brain of a modified vaccinia virus Ankara (MVA) vector encoding for a suicide gene (FCU1) tha...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2009.12.012
更新日期：2010-03-01 00:00:00
abstract：:The aim of this work is to assess the use of (SPOT) multispectral visible infrared remote sensing to study microphytobentos assemblages in a shellfish ecosystem (Bay of Bourgneuf, France). SPOT satellite images (acquired at low tide in spring or autumn between 1986 and 1998) were calibrated using in situ radiometric d...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/s1631-0691(03)00125-2
更新日期：2003-04-01 00:00:00
abstract：:Daily numbers of deaths at a regional level were collected in 16 European countries. Summer mortality was analyzed for the reference period 1998-2002 and for 2003. More than 70,000 additional deaths occurred in Europe during the summer 2003. Major distortions occurred in the age distribution of the deaths, but no harv...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2007.12.001
更新日期：2008-02-01 00:00:00
abstract：:In a previous study, we showed that estimates of the BSE epidemic in France were censored by cattle mortality and by a lack of diagnosis. Indeed, we estimated that 51 300 cattle were infected by the BSE agent between 1987 and 1997, whereas only 103 clinical BSE cases were detected by the passive surveillance system up...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2005.12.004
更新日期：2006-02-01 00:00:00
abstract：:Potato is the fourth staple food in the world, following rice, wheat, and maize, whereas tubers contain high quality of starch, relatively high amounts of vitamin C and many other important substances. It also contains relatively good quality of protein (about 3 to 6% of the dried weight) and patatin, and 11S globulin...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2013.09.002
更新日期：2013-09-01 00:00:00
abstract：:This Note presents experimental evidence that a hyperbolic tissue flow plays an important role in the establishment of the organization plan of vertebrates. We have followed the development of chicken embryos from the gastrula stage up to the moment when the body plan is recognizable. We have found that establishment ...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2011.03.010
更新日期：2011-07-01 00:00:00
abstract：:In the frame of the largest French project of artificial production reefs, initiated by the city of Marseilles in 2001, the present study aimed at describing the hydrodynamic pattern of the coastal area considered, by the use of a 3D numerical modelling. Results were local wind statistics, bottom current fields and dr...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2006.04.002
更新日期：2006-07-01 00:00:00
abstract：:Meiosis is a specialized cell division at the origin of the haploid cells that eventually develop into the gametes. It therefore lies at the heart of Mendelian heredity. Recombination and redistribution of the homologous chromosomes arising during meiosis constitute an important source of genetic diversity, conferring...
journal_title：Comptes rendus biologies
pub_type： 杂志文章,评审
doi：10.1016/j.crvi.2016.04.003
更新日期：2016-07-01 00:00:00
abstract：:Choosing a suitable habitat is a main step in the settlement process, particularly for species having weak movement abilities. Reliable cues are thus needed for habitat selection. In silk-spinning arthropods, silk can be used as a social cue to select an appropriate location. Silk can also provide information on the p...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2012.07.001
更新日期：2012-08-01 00:00:00
abstract：:The Mediterranean stone pine Pinus pinea L. (gymnosperm, Pinaceae) is much appreciated for its seed production, widely used in food preparation in the Mediterranean Basin. Seeds contain 25% proteins on a dry-weight basis. Pinus pinea accumulate globulins as major storage proteins in seeds (75% of total storage protein...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2007.03.011
更新日期：2007-05-01 00:00:00
abstract：:5-(Hydroxymethyl)uracil, 5-formyluracil or 5-carboxyuracil can be formed in DNA upon exposure to ionizing radiations. We report the effect of the latter oxidative lesions on the in vitro transcription by T7 RNA polymerase using a single-stranded short model template. Kinetic experiments showed that the transcription y...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2005.07.003
更新日期：2005-09-01 00:00:00
abstract：:This study was undertaken to assess the risk of poisoning due to consumption of the puffer fish Lagocephalus lagocephalus collected along the Tunisian coast. Wistar rats were daily intraperitoneally injected, for 10 days, with acidic extracts of liver or flesh (muscles + skin) of L. lagocephalus. Control rats received...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2008.05.005
更新日期：2008-08-01 00:00:00
abstract：:Two ground-dwelling couas species, Coquerel's Coua Coua coquereli and Giant Coua Coua gigas, live in sympatry in the dry forest of Madagascar. These birds are typically insectivorous and mainly feed at ground level. The two species differ by size but have the same morphology, suggesting they have the same physical att...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2009.01.005
更新日期：2009-06-01 00:00:00
abstract：:This article starts with the observation of a non-linear relationship between health progress and economic development. This relationship is interpreted as resulting from a bidirectional interaction between these two variables, which may lead a country to a poverty trap or, alternatively, to a virtuous circle of econo...
journal_title：Comptes rendus biologies
pub_type： 杂志文章,评审
doi：10.1016/j.crvi.2008.08.004
更新日期：2008-12-01 00:00:00
abstract：:Several studies have demonstrated that, in a context of oxidative stress, resveratrol, a polyphenol found in wine, could act as a protective agent on endothelial cells by various mechanisms but without showing that it could penetrate inside the cell. The aim of this study was to detect for the first time resveratrol i...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2012.03.013
更新日期：2012-04-01 00:00:00
abstract：:Ancientness and maturity are two major qualities of forest ecosystems. They are components of naturalness and are affected by human impact. These qualities and the associated terms are often mixed up and incorrectly used. We have carried out a synthesis in order to propose an adapted French terminology based on intern...
journal_title：Comptes rendus biologies
pub_type： 杂志文章,评审
doi：10.1016/j.crvi.2014.10.004
更新日期：2015-01-01 00:00:00
abstract：:During the analysis of alien and invasive flora of Europe, as a threat to biodiversity, data for Croatia were missing. The aim of our research was to analyse distributional patterns and range size of all invasive alien plants (64) for the state area (57,000 km(2)). They were detected on 49% of the state territory, ave...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2013.01.003
更新日期：2013-02-01 00:00:00
abstract：:Advances in pharmacology and genomics, and their intervention in human biology are beyond our abilities to understand their consequences. Therapeutic intervention in highly complex, non-linear, adaptive biological systems results in some unforeseen and undesirable consequences. To do the most good with the least harm,...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2003.09.006
更新日期：2003-10-01 00:00:00
abstract：:The role of the eyes, and more precisely that of the ommatidian pigments, in the control of daily rhythms of movement of Daphnia longispina is investigated. In the laboratory, under permanent light (LL), the pigmentary modifications observed are globally similar to those observed in situ, except in their timing, aroun...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2003.09.037
更新日期：2003-12-01 00:00:00
abstract：:In this work we show how mathematical models and optimal control techniques can help us to solve some problems of environmental engineering, more precisely, water pollution problems arising from wastewater discharges into coastal areas or rivers. We deal with a complete two-dimensional mathematical model for the evolu...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2004.08.010
更新日期：2005-04-01 00:00:00
abstract：:Despite the fact that coverage is one of the most widely used descriptors for seagrass meadows, the spatial structure of coverage at mesoscale has not often been taken into account. The present work investigates the structure of P. oceanica coverage at mesoscale and its possible relationship with several factors (dept...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2006.05.001
更新日期：2006-09-01 00:00:00
abstract：:Wheat (Triticum aestivum L.) is one of the most important agricultural crops worldwide. However, water is the most important limiting factor for wheat production. This study was initiated to test water stress environmental effects on grain quality and nutritional value of wheat by using single different water conditio...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2009.03.003
更新日期：2009-08-01 00:00:00
abstract：:The present study focuses on the potential of glucose oxidase (GOD) as a promising biocontrol agent for fungal plant pathogens. In fact, a new GOD producing fungus was isolated and identified as an Aspergillus tubingensis. GOD (125 AU) has been found to inhibit Fusarium solani growth and spore production. Indeed, GOD ...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2015.05.007
更新日期：2015-10-01 00:00:00
abstract：:Since the early 2000s, the genus Buthus Leach, 1815 (family Buthidae) has been the subject of an important number of studies. These concerned particularly the species belonging to the 'Buthus occitanus' complex. A number of populations previously considered as subspecies or varieties of B. occitanus Leach were raised ...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2015.10.002
更新日期：2016-01-01 00:00:00
abstract：:Patterns of wear on the canine teeth were examined in 260 adult male babirusa skulls. Video recordings of 161 adult male babirusas at salt licks in North Sulawesi were viewed for behaviour related to erosion of the canine teeth. Corresponding observations were made of the behaviour of male babirusa in Antwerp and Sura...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2017.03.006
更新日期：2017-05-01 00:00:00
abstract：:Sleep disorders have a high prevalence: around 20% of insomniacs, 10% hypersomnolent including 2 to 4% of sleep disordered breathing in the general adult population. The low availability of sleep centres implies the research of alternative recording techniques in the natural setting of the patient. The objective was t...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/s1631-0691(02)01437-3
更新日期：2002-04-01 00:00:00
abstract：:A fine regulation of the amiloride-sensitive Epithelial Sodium Channel (ENaC), made of alpha, beta and gamma subunits, is crucial for maintenance of Na+ balance and blood pressure. Both beta- and gamma-ENaC participate in negative regulation by interacting with Nedd4-2, an E3 ubiquitin-ligase. Disruption of this inter...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/s1631-0691(03)00154-9
更新日期：2003-07-01 00:00:00
abstract：:The evidence for amphibian population declines is based on count data that were not adjusted for detection probabilities. Such data are not reliable even when collected using standard methods. The formula C = Np (where C is a count, N the true parameter value, and p is a detection probability) relates count data to de...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/s1631-0691(03)00048-9
更新日期：2003-08-01 00:00:00
abstract：:Epilithic diatom communities are particularly suitable for the evaluation of freshwater quality. In Ecuador, however, no water quality index includes this biotic parameter. This work is the first attempt in the country to determine the composition of epilithic diatom communities associated with different degrees of eu...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2018.03.008
更新日期：2018-04-01 00:00:00
