Abstract：
:A report that serum prolactin concentrations were almost doubled by the use of copper IUDs led us to study the effect of both copper and inert IUDs. We studied 105 normal women in whom all other prolactinergic factors had been excluded; 25 of them were using copper IUDs, 25 were using inert IUDs and there were 55 controls. No differences were found in the mean prolactin levels between these groups (4.3, 4.5 and 4.3 microgram/l, respectively). We conclude that copper and inert IUDs do not affect prolactin secretion. :The results of a cross-sectional study designed to determine the effects of IUD material (i.e., copper or inert) on prolactin levels in serum are presented. A consecutive series of 105 healthy volunteers were studied. Prolactin was measured by radioimmunoassay. The serum prolactin determinations obtained are shown figuratively; there were no significant differences between the geometric mean values in women (n=25) with copper (4.3 mcgm/liter) or inert IUDs (n=25) (4.5 mcgm liter) or controls (4.3 mcgm); nor were differences discernable between the combined IUD groups (4.4) compared with controls (P .86 in all cases). Copper and inert IUDs do not affect prolactin secretion.
journal_name
Contraceptionjournal_title
Contraceptionauthors
Ransom WT,Chapman RS,Hull MGdoi
10.1016/0010-7824(79)90049-0subject
Has Abstractpub_date
1979-11-01 00:00:00pages
441-6issue
5eissn
0010-7824issn
1879-0518pii
0010-7824(79)90049-0journal_volume
20pub_type
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