Abstract:
:Bronchiolitis obliterans (BO) is a rare disease in immunocompetent children that usually occurs after infection of the lower airways. While a diagnosis of BO was usually confirmed by lung biopsy, identification of prior lung lesion plus a typical clinical course and a suggestive chest X-ray and CT scan have replaced the need for more invasive procedures. The authors reviewed the clinical records of 10 BO patients, followed in the Outpatients Paediatric Pulmonology Unit from January 1997 to December 2002, to identify the most common aetiology, clinical and radiological profiles, treatment and course. All patients maintained cough and/or wheezing after the initial acute episode. 80% had failure to thrive at the time of the diagnosis, mean age 16 months. Viral pneumonia was the main initial event (5 adenovirus, 3 respiratory syncytial virus, 1 parainfluenza virus, 1 unknown). Lung biopsies were not performed as clinical and radiological presentations were typical of BO. The follow-up (mean 36 months) revealed clinical resolution in 3 children and persistent symptoms in 6. One patient had progressive respiratory failure and died. Prompt recognition of the diagnosis with supportive treatment that included oxygen therapy and an aggressive nutrition plan helped to improve the clinical state of the children.
journal_name
Rev Port Pneumoljournal_title
Revista portuguesa de pneumologiaauthors
Lobo AL,Guardiano M,Nunes T,Azevedo I,Vaz LGsubject
Has Abstractpub_date
2007-07-01 00:00:00pages
495-509issue
4eissn
0873-2159issn
2172-6825pii
S0873-2159(15)30361-5journal_volume
13pub_type
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journal_title:Revista portuguesa de pneumologia
pub_type: 杂志文章
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journal_title:Revista portuguesa de pneumologia
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更新日期:2009-07-01 00:00:00
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更新日期:2014-07-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
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更新日期:2014-01-01 00:00:00
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更新日期:2005-03-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
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更新日期:2014-05-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
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更新日期:2010-03-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
pub_type: 杂志文章
doi:
更新日期:2006-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s2173-5115(09)70106-x
更新日期:2009-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0873-2159(15)30232-4
更新日期:2008-03-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1016/s0873-2159(15)30196-3
更新日期:2009-11-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
pub_type: 杂志文章
doi:10.1016/j.rppneu.2013.01.001
更新日期:2013-07-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
pub_type: 杂志文章
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更新日期:2009-09-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
pub_type: 杂志文章
doi:10.1016/j.rppneu.2013.04.002
更新日期:2014-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0873-2159(15)30590-0
更新日期:2004-07-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
pub_type: 杂志文章,评审
doi:
更新日期:2007-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0873-2159(15)30619-x
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更新日期:2011-11-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
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更新日期:2014-11-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
pub_type: 杂志文章
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更新日期:2004-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2009-05-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2010-07-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
pub_type: 杂志文章
doi:10.1016/s0873-2159(15)30032-5
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journal_title:Revista portuguesa de pneumologia
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
pub_type: 杂志文章
doi:10.1016/j.rppneu.2011.07.006
更新日期:2012-03-01 00:00:00
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journal_title:Revista portuguesa de pneumologia
pub_type: 杂志文章
doi:10.1016/s0873-2159(15)30572-9
更新日期:2004-03-01 00:00:00