Abstract：
:A 28-year-old neuromuscular patient chronically treated with nocturnal noninvasive ventilation developed pulmonary lobar atelectasis and daytime hypoxemia. Twenty four-hour 5L/min oxygen was begun, while mechanical cough assist aids were applied for seven days. In the following three days, treatment with nebulized Dornase alpha (rhDNase) b.i.d. was tested, without any significant improvement. On 11 and 13th days rhDNase was instilled by flexible bronchoscopy. A rapid resolution of the atelectasis was observed with relief of hypoxemia, without significant side effects. On day 16 the patient was discharged without oxygen requirements. In non-intubated neuromuscular patients with atelectasis who do not respond successfully to non-invasive treatments intrabronchial instillation of rhDNase may safely help to improve airway clearance.
journal_name
Rev Port Pneumoljournal_title
Revista portuguesa de pneumologiaauthors
Crescimanno G,Marrone Odoi
10.1016/j.rppneu.2012.12.002subject
Has Abstractpub_date
2014-01-01 00:00:00pages
42-5issue
1eissn
0873-2159issn
2172-6825pii
S0873-2159(13)00022-6journal_volume
20pub_type
杂志文章abstract：:Benign metastasizing leiomyomas of the lung are rare smooth muscle cells tumours. We report the case of a 48 year-old female who was evaluated due to persistent cough, progressive dyspnoea and constitutional symptoms. Chest computed tomography revealed a left endobronchial mass, multiple parenchyma nodules and a pleur...
journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
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更新日期：2010-11-01 00:00:00
abstract：UNLABELLED:Asthma is a chronic illness of the airways that can reduce respiratory muscle strength due to the resulting hyperinflation or treatment with corticosteroids. One of the ways to evaluate this respiratory muscular weakness is the Maximal Inspiratory Pressure (PImax). METHODS:A systematic review of the databas...
journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章,评审
doi：
更新日期：2010-05-01 00:00:00
abstract：INTRODUCTION:Surgical lung biopsy is a technique that presents a morbi-mortality rate of considerable importance. We analyze our experience with surgical lung biopsies for the diagnosis of diffuse lung disease and the effect produced on the indications for surgical biopsy in these pathologies after the publication of t...
journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
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abstract：:Lung cancer is considered an environment-related disease that develops as a consequence of exposure to mutagenic agents, namely those present in tobacco. The CYP1A1 gene codifies the phase I enzyme aryl hydrocarbon hydroxilase (AHH) belonging to the cytochrome P450 system that plays a major role in the bio-activation ...
journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/s2173-5115(09)70106-x
更新日期：2009-03-01 00:00:00
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：10.1016/j.rppneu.2014.03.007
更新日期：2014-11-01 00:00:00
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
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journal_title：Revista portuguesa de pneumologia
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pub_type： 杂志文章,多中心研究
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：10.1016/s0873-2159(15)30077-5
更新日期：2010-09-01 00:00:00
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：10.1016/s0873-2159(15)30578-x
更新日期：2004-05-01 00:00:00
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：10.1016/s0873-2159(15)30677-2
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：10.1016/j.rppneu.2012.01.006
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：10.1016/s0873-2159(15)30112-4
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/s0873-2159(15)30232-4
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：
更新日期：2009-07-01 00:00:00
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：10.1016/s0873-2159(15)30557-2
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：
更新日期：2009-09-01 00:00:00
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：10.1016/j.rppneu.2013.04.002
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：10.1016/j.rppneu.2011.03.002
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：10.1016/s0873-2159(15)30684-x
更新日期：2003-07-01 00:00:00
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：10.1016/S0873-2159(15)30324-X
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journal_title：Revista portuguesa de pneumologia
pub_type： 杂志文章
doi：10.1016/j.rppneu.2011.06.003
更新日期：2012-01-01 00:00:00
