Abstract：
:Acute infantile bilateral striatal necrosis is a rarely described acute neurological syndrome associated with radiological findings. Its etiology and pathogenic mechanisms are unknown. Clinically, the syndrome usually follows respiratory illnesses and presents with an array of neurological findings, including axial ataxia, grimacing, mutism, head nodding, and high-pitched cry. This study follows a child with acute infantile bilateral striatal necrosis both clinically and radiologically. In addition, for the first time, the authors describe the serial findings of single-photon emission computed tomography (SPECT) from onset of illness through 20 months. Their findings indicate an initial insult apparent on both magnetic resonance imaging and SPECT localized to the basal ganglia, which, although improved over time, does not fully regress. The residual lesion on SPECT was clinically associated with only mild attention deficit disorder and no motor pathology. The authors review the published literature concerning acute infantile bilateral striatal necrosis and suggest possible mechanisms of this poorly understood and probably underreported condition.
journal_name
J Child Neuroljournal_title
Journal of child neurologyauthors
Zevit N,Steinmetz A,Kornreich L,Straussberg Rdoi
10.1177/0883073807304194subject
Has Abstractpub_date
2007-10-01 00:00:00pages
1222-6issue
10eissn
0883-0738issn
1708-8283pii
22/10/1222journal_volume
22pub_type
杂志文章abstract：:A 2-year-old boy with an initial diagnosis of Hunter syndrome (mucopolysaccharidosis II) had a more severe phenotype than expected, which warranted further evaluation. The patient had severe infantile global neurodevelopmental delays, macrocephaly with a prominent forehead, coarse facial features with clear corneas, c...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073811425860
更新日期：2012-06-01 00:00:00
abstract：:The size and reactivity to light of the pupil in infants with intraventricular hemorrhage has been variously described in the literature. These descriptions have included miosis, reactivity to light, nonreactivity to light, and anisocoria. We studied the size and light reactivity of 20 infants with intraventricular he...
journal_title：Journal of child neurology
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doi：10.1177/088307389400900423
更新日期：1994-10-01 00:00:00
abstract：BACKGROUND:We developed and validated a Spanish seizure screen for children based on a previously validated English seizure screen that could be administered by a trained research assistant in a 2-step process, approximating the clinical diagnostic process of a pediatric epilepsy specialist. This questionnaire was desi...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073820978001
更新日期：2020-12-18 00:00:00
abstract：:Ischemic stroke in the young is uncommon, but we currently evaluate at least one young stroke patient at our institutions each week. We undertook this chart review of strokes in patients between the ages of 6 months and 39 years to review all conditions associated with, and thus possibly contributory to, the stroke. W...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307389300800311
更新日期：1993-07-01 00:00:00
abstract：:Childhood leukoencephalopathies are a broad class of diseases, which are extremely rare. The treatment and classification of these disorders are both challenging. Nearly half of children presenting with a leukoencephalopathy remain without a specific diagnosis. Leukoencephalopathy with thalamus and brain stem involvem...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073816630087
更新日期：2016-06-01 00:00:00
abstract：:Corpus callosum agenesis, retardation, adducted thumbs, spastic paraparesis, and hydrocephalus (CRASH syndrome) is an X-linked recessive disorder caused by mutations in the neuronal cell adhesion molecule L1 (LICAM) gene. L1 plays a key role in axon outgrowth and pathfinding during the development of the nervous syste...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307380001500407
更新日期：2000-04-01 00:00:00
abstract：:This study was conducted to determine the occurrence, severity, and risk factors of gingival enlargement in children treated with valproate and other nonvalproate antiepileptic drugs. A cross-sectional study was carried out in which data obtained from 68 epileptic children under treatment were compared with those from...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/08830738040190120901
更新日期：2004-12-01 00:00:00
abstract：:Despite the recent development of new antiepilepsy drugs, a significant number of children are still unable to achieve seizure freedom without side effects. Understanding the factors behind individual variability in antiepilepsy drug tolerability and dose response and incorporating these factors into a treatment plan ...
journal_title：Journal of child neurology
pub_type： 杂志文章,评审
doi：10.1177/08830738020170011301
更新日期：2002-01-01 00:00:00
abstract：:Subacute sclerosing panencephalitis (SSPE) typically presents with progressive mental deterioration, behavioral changes, and myoclonic jerks. Atypical presentations are not unknown and may result in diagnostic delays. A 9-year-old girl presented with poor balance and ataxia following an episode of upper respiratory tr...
journal_title：Journal of child neurology
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doi：10.1177/0883073808330184
更新日期：2009-07-01 00:00:00
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journal_title：Journal of child neurology
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更新日期：2014-11-01 00:00:00
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journal_title：Journal of child neurology
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doi：10.1177/0883073810381446
更新日期：2011-03-01 00:00:00
abstract：:The intrauterine onset of convulsive syndromes has been documented only rarely, and previous reports have lacked detailed neuropathologic description. This report details a case of severe, intractable myoclonic encephalopathy, which, on the basis of severely abnormal paroxysmal fetal movement patterns confirmed by ant...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307389300800210
更新日期：1993-04-01 00:00:00
abstract：:The cerebellum undergoes a protracted development, making it particularly vulnerable to a broad spectrum of developmental events. Acquired destructive and hemorrhagic insults may also occur. The main steps of cerebellar development are reviewed. The normal imaging patterns of the cerebellum in prenatal ultrasound and ...
journal_title：Journal of child neurology
pub_type： 杂志文章,评审
doi：10.1177/0883073811420148
更新日期：2011-12-01 00:00:00
abstract：:Attention Deficit Hyperactivity Disorder (ADHD) is associated with altered cerebellar volume and cerebellum is associated with cognitive performance. However there are mixed results regarding the cerebellar volume in young patients with ADHD. To clarify the size and direction of this effect, we conducted the analysis ...
journal_title：Journal of child neurology
pub_type： 杂志文章,多中心研究
doi：10.1177/0883073816678550
更新日期：2017-02-01 00:00:00
abstract：:Maternal intrauterine inflammation has been implicated in the development of periventricular leukomalacia and white matter injury in the neonate. We hypothesized that intrauterine endotoxin administration would lead to microstructural changes in the neonatal rabbit white matter in vivo that could be detected at birth ...
journal_title：Journal of child neurology
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doi：10.1177/0883073809338213
更新日期：2009-09-01 00:00:00
abstract：:The potential benefits of functional magnetic resonance imaging (MRI) for the investigation of normal development have been limited by difficulties in its use with children. We describe the practical aspects, including failure rates, involved in conducting large-scale functional MRI studies with normal children. Two h...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/08830738020170122201
更新日期：2002-12-01 00:00:00
abstract：:The clinical picture, family history, laboratory data, treatment modalities, and outcome in 27 juvenile myasthenics seen over a 25-year period are presented. Onset was after 10 years of age in the majority of patients. Half presented with ocular signs, the other half with generalized-onset myasthenia. Half of those wi...
journal_title：Journal of child neurology
pub_type： 杂志文章,评审
doi：10.1177/088307389300800422
更新日期：1993-10-01 00:00:00
abstract：:To contribute to characterize electroencephalographic (EEG) activity in pediatric anti-N-methyl-d-aspartate (anti-NMDA) receptor encephalitis, we reviewed electroclinical data of 5 children with anti-NMDA receptor encephalitis diagnosed in our department. We identified 4 longitudinal electroencephalographic phases: in...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073813515947
更新日期：2015-02-01 00:00:00
abstract：:Neuromyelitis optica is a rare, severe idiopathic disease that predominantly involves optic nerves and spinal cord. Main clinical features of neuromyelitis optica are visual loss, paraparesis or tetraparesis, sensory loss, and sphincter dysfunction. A 13-year-old girl with vision loss and behavioral change was admitte...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073812448837
更新日期：2013-05-01 00:00:00
abstract：:Abnormal cerebral venous drainage is associated with hypoxia and glucose deprivation, which can account for progressive neurologic deterioration in Sturge-Weber syndrome. Although developmental delay is common in Sturge-Weber syndrome, bihemispheric calcification is uncommon. Computed tomography (CT) and magnetic reso...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307389801301203
更新日期：1998-12-01 00:00:00
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journal_title：Journal of child neurology
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doi：10.1177/0883073810361382
更新日期：2010-05-01 00:00:00
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journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073811435240
更新日期：2012-10-01 00:00:00
abstract：:Neonatal seizures are one of the most common neurological disorders in infants. However, the optimal treatment strategy for neonatal seizures remains controversial and there is little data regarding current treatment of neonatal seizures. In this study we describe the current treatment of neonatal seizures and variati...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073808321056
更新日期：2009-02-01 00:00:00
abstract：OBJECTIVES:The objectives were to investigate the relationship between ketogenic diet therapy and neutropenia in children with epilepsy. METHODS:A retrospective chart review of children who initiated ketogenic diet at the Hospital for Sick Children between January 1, 2000, and May 1, 2018 was performed. Factors associ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073820984067
更新日期：2021-01-04 00:00:00
abstract：:A case of a 5-day-old newborn with rhizomelic chondrodysplasia punctata was investigated with multivoxel magnetic resonance spectroscopy, including chemical shift imaging maps, which disclosed a decrease in the choline peak and the choline signal intensity, respectively, in the right cerebral hemisphere. This is the s...
journal_title：Journal of child neurology
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更新日期：2005-08-01 00:00:00
abstract：:This study explored verbal, visual, motor, and tactile humor appreciation and comprehension among preschool children with epilepsy as compared with healthy children. Participants included 32 children with focal epilepsy, as well as 70 healthy controls. The results suggest that children with epilepsy assess humor dicho...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073811419259
更新日期：2012-03-01 00:00:00
abstract：:Acute disseminated encephalomyelitis is a monophasic inflammatory demyelinating disease of the central nervous system involving the white matter, and to a lesser extent, the gray matter. Bilateral thalamic lesions have been reported in 12% of pediatric patients with acute disseminated encephalomyelitis. In most cases,...
journal_title：Journal of child neurology
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doi：10.1177/0883073808331364
更新日期：2009-08-01 00:00:00
abstract：:At present, both migraine and tension-type headaches in children are believed to be chronic primary headaches. Meningeal signs in both cases are ignored or not examined, and the neurologic status is considered normal. This is the first study that focuses on meningeal signs in children with chronic headaches. The study...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/08830738060210050601
更新日期：2006-05-01 00:00:00
abstract：:Generalized edema can occur during the course of juvenile dermatomyositis. In this article, a 4-year-old boy with generalized nonpitting edema and proximal weakness is reported. Characteristic cutaneous lesions, laboratory tests, results of electromyography, and magnetic resonance imaging findings resulted in a diagno...
journal_title：Journal of child neurology
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更新日期：2008-11-01 00:00:00
