Practical aspects of conducting large-scale functional magnetic resonance imaging studies in children.

Abstract:

:The potential benefits of functional magnetic resonance imaging (MRI) for the investigation of normal development have been limited by difficulties in its use with children. We describe the practical aspects, including failure rates, involved in conducting large-scale functional MRI studies with normal children. Two hundred and nine healthy children between the ages of 5 and 18 years participated in a functional MRI study of language development. Reliable activation maps were obtained across the age range. Younger children had significantly higher failure rates than older children and adolescents. It is concluded that it is feasible to conduct large-scale functional MRI studies of children as young as 5 years old. These findings can be used by other research groups to guide study design and plans for recruitment of young subjects.

journal_name

J Child Neurol

authors

Byars AW,Holland SK,Strawsburg RH,Bommer W,Dunn RS,Schmithorst VJ,Plante E

doi

10.1177/08830738020170122201

subject

Has Abstract

pub_date

2002-12-01 00:00:00

pages

885-90

issue

12

eissn

0883-0738

issn

1708-8283

journal_volume

17

pub_type

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