Thermal dosimetry and temperature measurements.

Abstract:

:A crucial ingredient of any hyperthermia procedure is the accurate measurement of achieved temperature. In this paper, we present some accuracy and resolution suggestions and address the problem of temperature measurements when electromagnetic energy is used as the mode of heating. In such cases, conventional metallic thermometers can cause severe errors due to reradiated fields, high internal healing, and electronic interference. To avoid these problems, several groups have developed either high-resistance lead thermometers or optical-fiber probes using a variety of sensors, including birefringent and semiconductor crystals. A new noninvasive approach uses ultrasound-computed tomography and relies upon the change in the speed of sound versus temperature to achieve maps of internal tissue temperature.

journal_name

Cancer Res

journal_title

Cancer research

authors

Christensen DA

subject

Has Abstract

pub_date

1979-06-01 00:00:00

pages

2325-7

issue

6 Pt 2

eissn

0008-5472

issn

1538-7445

journal_volume

39

pub_type

杂志文章
  • Plasmin-catalyzed proteolysis in colorectal neoplasia.

    abstract::The expression of different components of the plasminogen activator (PA)/plasmin system was explored in a series of colorectal neoplasia. We have found that urokinase (uPA) and urokinase receptor (uPA-R) gene expression is upregulated in adenomas and carcinomas, and that uPA/uPA-R production is confined to stromal cel...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Delbaldo C,Cunningham M,Vassalli JD,Sappino AP

    更新日期:1995-10-15 00:00:00

  • Analysis of prolactin and growth hormone production in hyperplastic and neoplastic rat pituitary tissues by the hemolytic plaque assay.

    abstract::The reverse hemolytic plaque assay (RHPA) was used to detect hormone release from cultured normal, hyperplastic, and neoplastic rat pituitary cells. Hyperplastic pituitary cells were produced by s.c. diethylstilbestrol (DES) treatment (10 mg in Silastic tubes) for 3, 6, and 9 weeks. Neoplastic pituitary cells from rat...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Lloyd RV,Coleman K,Fields K,Nath V

    更新日期:1987-02-15 00:00:00

  • Topography of nonneoplastic and neoplastic cells of common origin.

    abstract::The possibility that neoplastic transformation may characteristically alter cell surface morphology prompted a comparison by scanning electron microscopy of nonneoplastic and tumorigenic cell lines from a single clone of mouse embryo cells. Among those studied by scanning electron microscopy, six lines of this clone p...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Wetzel B,Sanford KK,Fox CH,Jones GM,Westbrook EW,Tarone RE

    更新日期:1977-03-01 00:00:00

  • Restricted T-cell receptor repertoire in melanoma metastases regressing after cytokine therapy.

    abstract::One major rationale for using interleukin-2 and IFN-alpha in cancer immunotherapy is to activate tumor-specific T cells at the tumor site. To study the in situ T-cell response, we determined the T-cell receptor (TCR) repertoire in six melanoma metastases regressing after cytokine treatment obtained from five patients....

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Willhauck M,Scheibenbogen C,Pawlita M,Möhler T,Thiel E,Keilholz U

    更新日期:2003-07-01 00:00:00

  • Efficient oncolysis by a replicating adenovirus (ad) in vivo is critically dependent on tumor expression of primary ad receptors.

    abstract::Replicating adenoviruses (Ads) are designed to replicate in and destroy cancer cells, generating viral progeny that spread within the tumor. To address the importance of the primary cellular receptor for Ads, the coxsackievirus and Ad receptor (CAR), in permitting intratumoral spread of a replicating Ad, we have used ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Douglas JT,Kim M,Sumerel LA,Carey DE,Curiel DT

    更新日期:2001-02-01 00:00:00

  • RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN.

    abstract::Therapeutic inhibition of mammalian target of rapamycin (mTOR) in cancer is complicated by the existence of a negative feedback loop linking mTOR to the phosphatidylinositol 3-kinase (PI3K)-Akt pathway. Thus, mTOR inhibition by rapamycin or TSC1/2 results in increased PI3K-Akt activation. The death domain kinase recep...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-09-0474

    authors: Park S,Zhao D,Hatanpaa KJ,Mickey BE,Saha D,Boothman DA,Story MD,Wong ET,Burma S,Georgescu MM,Rangnekar VM,Chauncey SS,Habib AA

    更新日期:2009-05-15 00:00:00

  • Metabolic activation of 6-nitrochrysene in explants of human bronchus and in isolated rat hepatocytes.

    abstract::It has previously been shown that 6-nitrochrysene can be activated to electrophilic species capable of reacting with DNA through metabolic pathways that form N-hydroxy-6-aminochrysene or trans-1,2-dihydroxy-1,2-dihydro-6-aminochrysene as critical intermediates. Since the lung is a known target tissue for the carcinoge...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Delclos KB,el-Bayoumy K,Casciano DA,Walker RP,Kadlubar FF,Hecht SS,Shivapurkar N,Mandal S,Stoner GD

    更新日期:1989-06-01 00:00:00

  • Calcium/calmodulin-dependent kinase I and calcium/calmodulin-dependent kinase kinase participate in the control of cell cycle progression in MCF-7 human breast cancer cells.

    abstract::Calcium is universally required for cell growth and proliferation. Calmodulin is the main intracellular receptor for calcium. Although calcium and calmodulin are well known to be required for cell cycle regulation, the target pathways for their action remain poorly defined. Potential targets include the calcium/calmod...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-05-0271

    authors: Rodriguez-Mora OG,LaHair MM,McCubrey JA,Franklin RA

    更新日期:2005-06-15 00:00:00

  • The effects of specific antibody-complement-mediated cytotoxicity on transformed and untransformed Syrian hamster cells.

    abstract::Antibodies were produced against 220,000-molecular-weight proteins of Syrian hamster embryo cells. The antiserum containing these antibodies is capable of immunologically staining the surfaces and a fibrillar network around untransformed Syrian hamster embryo cells. The staining is removed by adsorption of the antiser...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Clarke SM,Fink LM

    更新日期:1977-09-01 00:00:00

  • Role of amino acid depletion in combined treatment of neoplastic cells with methotrexate and L-asparaginase.

    abstract::The effect of pretreatment with L-asparaginase on the cytotoxicity of methotrexate (MTX) was studied in L5178Y murine leukemic cells and L-929 cells grown in vitro. The results were correlated with the effects of L-asparaginase on DNA synthesis. At low concentrations of the enzyme, pretreatment of cells enhanced the e...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Chlopkiewicz B,Koziorowska J

    更新日期:1975-06-01 00:00:00

  • Defects in methylthioadenosine phosphorylase are associated with but not responsible for methionine-dependent tumor cell growth.

    abstract::A large proportion of human tumor-derived cell lines and primary tumor cells show methionine-dependent growth. This phenomenon refers to the ability of cells to grow in media containing methionine and the inability of cells to grow in media supplemented with methionine's precursor, homocysteine (Hcy). Methionine can b...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Tang B,Li YN,Kruger WD

    更新日期:2000-10-01 00:00:00

  • Cyclin D1 activity regulates autophagy and senescence in the mammary epithelium.

    abstract::Overexpression of cyclin D1 is believed to endow mammary epithelial cells (MEC) with a proliferative advantage by virtue of its contribution to pRB inactivation. Accordingly, abrogation of the kinase-dependent function of cyclin D1 is sufficient to render mice resistant to breast cancer initiated by ErbB2. Here, we re...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-11-4139

    authors: Brown NE,Jeselsohn R,Bihani T,Hu MG,Foltopoulou P,Kuperwasser C,Hinds PW

    更新日期:2012-12-15 00:00:00

  • Serum hormones and lipoproteins in benign breast disease.

    abstract::Seventeen young women with clinically confirmed mammary dysplasia and six age-matched controls were treated with alpha-tocopherol. Serum samples collected during the luteal phase of each woman at monthly intervals for the 4-month duration of the study were analyzed for serum luteinizing hormone, follicle-stimulating h...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Sundaram GS,London R,Margolis S,Wenk R,Lustgarten J,Nair PP,Goldstein P

    更新日期:1981-09-01 00:00:00

  • Gonadotropin-releasing hormone (GnRH) antagonists promote proapoptotic signaling in peripheral reproductive tumor cells by activating a Galphai-coupling state of the type I GnRH receptor.

    abstract::Gonadotropin-releasing hormone (GnRH) receptor agonists are extensively used in the treatment of sex hormone-dependent cancers via the desensitization of pituitary gonadotropes and consequent decrease in steroid sex hormone secretion. However, evidence now points to a direct inhibitory effect of GnRH analogs on cancer...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-04-1360

    authors: Maudsley S,Davidson L,Pawson AJ,Chan R,López de Maturana R,Millar RP

    更新日期:2004-10-15 00:00:00

  • Dissimilar effects of phorbol ester and diacylglycerol derivative on protein kinase activity in the monoblastoid U937 cell.

    abstract::Mechanism, in addition to protein kinase C activation may mediate 12-O-tetradecanoylphorbol-13-acetate (TPA) stimulated differentiation of leukemic cells. We compared the effect of pretreating intact monoblastoid U937 cells with TPA or the diacylglycerol derivative, 1-oleoyl-2-acetylglycerol (OAG), by studying the pro...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Ways DK,Dodd RC,Earp HS

    更新日期:1987-07-01 00:00:00

  • Prognostic significance of HER2 and HER4 coexpression in childhood medulloblastoma.

    abstract::Recent in vitro studies of the epidermal growth factor receptor (EGFR) family have revealed complex signaling interactions involving the production of ligand-mediated heterodimers synergistic for the transformation of cells in vitro. In a series of 70 patients with childhood medulloblastoma, we have used immunohistoch...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Gilbertson RJ,Perry RH,Kelly PJ,Pearson AD,Lunec J

    更新日期:1997-08-01 00:00:00

  • The adaptor protein AMOT promotes the proliferation of mammary epithelial cells via the prolonged activation of the extracellular signal-regulated kinases.

    abstract::The asymmetric organization of epithelial cells is a basic counter to cellular proliferation. However, the mechanisms whereby pro-growth pathways are modulated by intracellular factors that control cell shape are not well understood. This study demonstrates that the adaptor protein Amot, in addition to its established...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-10-1995

    authors: Ranahan WP,Han Z,Smith-Kinnaman W,Nabinger SC,Heller B,Herbert BS,Chan R,Wells CD

    更新日期:2011-03-15 00:00:00

  • Comparison of virus-positive and virus-negative cases of feline leukemia and lymphoma.

    abstract::One hundred eighty-four cases of feline leukemia and lymphoma diagnosed in Boston from 1972 through 1976 were investigated. Fifty-eight % of these cases were lymphoma, and 42% were leukemia. Sixty-seven % of the cats had positive fluorescent antibody tests for circulating feline leukemia virus. The rest (33%) were vir...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Francis DP,Cotter SM,Hardy WD Jr,Essex M

    更新日期:1979-10-01 00:00:00

  • Human prostate tissue antigens defined by murine monoclonal antibodies.

    abstract::BALB/c mice were hyperimmunized against a membrane preparation derived from a pool of transurethral resection specimens which included three benign prostatic hyperplasia and one prostate adenocarcinoma tissue samples. The activated lymphocytes were fused with the NS-1 mouse myeloma cell line, and supernatants from imm...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Starling JJ,Sieg SM,Beckett ML,Wirth PR,Wahab Z,Schellhammer PF,Ladaga LE,Poleskic S,Wright GL Jr

    更新日期:1986-01-01 00:00:00

  • Epidemiology of alcohol and cancer.

    abstract::There is still insufficient knowledge of the distribution of drinking habits in human populations, and more descriptive surveys are needed. Both prospective and retrospective epidemiological studies indicate that alcohol consumption is a cancer hazard. Prospective studies on excessive drinkers have shown an increased ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Tuyns AJ

    更新日期:1979-07-01 00:00:00

  • Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer.

    abstract::Invasive breast cancer has a high risk of recurrence to incurable disease and needs improved prognostic and therapeutic tools. Our work combines clinical and molecular analyses to show that the transcriptional repressor HBP1 may be a new target for invasive breast cancer. Previous work indicated that HBP1 regulated pr...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-07-0567

    authors: Paulson KE,Rieger-Christ K,McDevitt MA,Kuperwasser C,Kim J,Unanue VE,Zhang X,Hu M,Ruthazer R,Berasi SP,Huang CY,Giri D,Kaufman S,Dugan JM,Blum J,Netto G,Wazer DE,Summerhayes IC,Yee AS

    更新日期:2007-07-01 00:00:00

  • Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1.

    abstract::Tumor metastasis is one of the most important clinical aspects of neoplastic disease because patient mortality is frequently attributable to disseminated rather than primary tumors. However, it still is not possible to definitively distinguish those individuals at high risk for disseminated disease, who would benefit ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Hunter KW,Broman KW,Voyer TL,Lukes L,Cozma D,Debies MT,Rouse J,Welch DR

    更新日期:2001-12-15 00:00:00

  • K-sam-related gene, N-sam, encodes fibroblast growth factor receptor and is expressed in T-lymphocytic tumors.

    abstract::We recently reported the isolation of the K-sam complementary DNA (cDNA), which was amplified preferentially in poorly differentiated types of stomach cancer and codes for one of the heparin-binding growth factor or fibroblast growth factor (FGF) receptor families. The K-sam-related gene, N-sam (NCC-IT-cell-derived sa...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Hattori Y,Odagiri H,Katoh O,Sakamoto H,Morita T,Shimotohno K,Tobinai K,Sugimura T,Terada M

    更新日期:1992-06-15 00:00:00

  • DNA damage induces alternative lengthening of telomeres (ALT) associated promyelocytic leukemia bodies that preferentially associate with linear telomeric DNA.

    abstract::The linear chromosomes of vertebrates terminate in telomeres that consist of a tandemly repeated hexameric sequence, 5'TTAGGG3'. Telomeres form a protective loop structure (t-loop), which is thought to prevent them from being recognized as a double-strand break. Approximately 10% of human tumors prevent shortening of ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-07-1556

    authors: Fasching CL,Neumann AA,Muntoni A,Yeager TR,Reddel RR

    更新日期:2007-08-01 00:00:00

  • Potentiation of nitrogen mustard cytotoxicity by disulfiram, diethyldithiocarbamic acid, and diethylamine in mice.

    abstract::Disulfiram (DSF) and its metabolites, diethyldithiocarbamic acid (DDC) and diethylamine (DEA), were studied as pretreatments in combination with the alkylating agent nitrogen mustard (HN2) on the cytotoxicity of HN2 against both leukemia cells and normal hematopoietic stem cells. Both time intervals and dose relations...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Valeriote F,Grates HE

    更新日期:1989-12-01 00:00:00

  • Immune response to a carcinoembryonic antigen polynucleotide vaccine.

    abstract::We have constructed a DNA plasmid encoding the full length complementary DNA for human carcinoembryonic antigen (CEA) driven by the cytomegalovirus early promoter/enhancer (plasmid DNA encoding human CEA) and demonstrated that this plasmid can function as a polynucleotide vaccine. This polynucleotide vaccine induced h...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Conry RM,LoBuglio AF,Kantor J,Schlom J,Loechel F,Moore SE,Sumerel LA,Barlow DL,Abrams S,Curiel DT

    更新日期:1994-03-01 00:00:00

  • A Microbial Siderophore-Inspired Self-Gelling Hydrogel for Noninvasive Anticancer Phototherapy.

    abstract::Microbial carboxyl and catechol siderophores have been shown to have natural iron-chelating abilities, suggesting that hyaluronic acid (HA) and the catechol compound, gallic acid (GA), may have iron-coordinating activities. Here, a photoresponsive self-gelling hydrogel that was both injectable and could be applied to ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-19-0975

    authors: Ko S,Park JY,Oh YK

    更新日期:2019-12-15 00:00:00

  • Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells.

    abstract::Thioguanine and mercaptopurine are prodrugs requiring conversion into thiopurine nucleotides to exert cytotoxicity. Thiopurine S-methyltransferase (TPMT), an enzyme subject to genetic polymorphism, catabolizes thiopurines into inactive methylated bases, but also produces methylthioguanine nucleotides and methylmercapt...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Dervieux T,Blanco JG,Krynetski EY,Vanin EF,Roussel MF,Relling MV

    更新日期:2001-08-01 00:00:00

  • Novel recombinant human b7-h4 antibodies overcome tumoral immune escape to potentiate T-cell antitumor responses.

    abstract::B7-H4 (VTCN1, B7x, B7s) is a ligand for inhibitory coreceptors on T cells implicated in antigenic tolerization. B7-H4 is expressed by tumor cells and tumor-associated macrophages (TAM), but its potential contributions to tumoral immune escape and therapeutic targeting have been less studied. To interrogate B7-H4 expre...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-12-3457

    authors: Dangaj D,Lanitis E,Zhao A,Joshi S,Cheng Y,Sandaltzopoulos R,Ra HJ,Danet-Desnoyers G,Powell DJ Jr,Scholler N

    更新日期:2013-08-01 00:00:00

  • Microsatellite instability of germ cell tumors is associated with resistance to systemic treatment.

    abstract::Systemic cisplatin-based chemotherapy cures > or =90% of patients with metastatic germ cell tumors (GCTs). The biological basis of this exquisite chemo-sensitivity and the resistant phenotype encountered in 10-15% of patients with GCT is yet unclear. A defective mismatch repair pathway leading to microsatellite instab...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Mayer F,Gillis AJ,Dinjens W,Oosterhuis JW,Bokemeyer C,Looijenga LH

    更新日期:2002-05-15 00:00:00