Long-term enhancement of synchronized oscillations by adrenergic receptor activation in the olfactory bulb.

Abstract:

:The noradrenergic system is widely thought to be important for associative learning in the olfactory system through actions in the first processing structure, the main olfactory bulb (MOB). Here, we used extracellular local field potential (LFP) and patch-clamp recordings in rat MOB slices to examine norepinephrine (NE)-induced long-term changes in circuit properties that might underlie learning. During responses to patterned olfactory nerve stimulation mimicking the breathing cycle, NE induced a long-term increase in gamma frequency (30-70 Hz) synchronized oscillations. The enhancement persisted long after washout of NE (

journal_name

J Neurophysiol

authors

Gire DH,Schoppa NE

doi

10.1152/jn.01324.2007

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

2021-5

issue

4

eissn

0022-3077

issn

1522-1598

pii

01324.2007

journal_volume

99

pub_type

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