Abstract:
:The noradrenergic system is widely thought to be important for associative learning in the olfactory system through actions in the first processing structure, the main olfactory bulb (MOB). Here, we used extracellular local field potential (LFP) and patch-clamp recordings in rat MOB slices to examine norepinephrine (NE)-induced long-term changes in circuit properties that might underlie learning. During responses to patterned olfactory nerve stimulation mimicking the breathing cycle, NE induced a long-term increase in gamma frequency (30-70 Hz) synchronized oscillations. The enhancement persisted long after washout of NE ( journal_name journal_title authors doi subject pub_date pages issue eissn issn pii journal_volume pub_type
abstract::1. The initial objective of this study was to determine whether respiratory-related neural assemblies exist in the brain stem midline. A second goal was to seek evidence for concurrent relationships among the neurons that could generate the detected synchrony. 2. Experiments were conducted on anesthetized, paralyzed, ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1992.67.4.905
更新日期:1992-04-01 00:00:00
abstract::We observed endocytosis in real time in stimulated frog motor nerve terminals by imaging the growth of large membrane infoldings labeled with a low concentration of FM dye. The spatial and temporal information made available by these experiments allowed us to image several new aspects of this synaptic vesicle recyclin...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00123.2011
更新日期:2011-08-01 00:00:00
abstract::We compared electroretinographic (ERG) responses to uniform-field and a variety of pattern stimuli using both transient and steady-state analyses. Evidence is provided that for all of these stimuli, the peak at high temporal frequencies in the steady-state response corresponds to the fast wave of the transient respons...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1984.51.5.952
更新日期:1984-05-01 00:00:00
abstract::Trace eyeblink classical conditioning (tEBCC) can be accelerated by making training trials contingent on the naturally generated hippocampal 3- to 7-Hz theta rhythm. However, it is not well-understood how the presence (or absence) of theta affects stimulus-driven changes within the hippocampus and how it correlates wi...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00801.2010
更新日期:2011-05-01 00:00:00
abstract::The inferior colliculus (IC) is highly modulated by descending projections from higher auditory and nonauditory centers. Traditionally, corticofugal fibers were believed to project mainly to the extralemniscal IC regions. However, there is some anatomical evidence suggesting that a substantial number of fibers from th...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00384.2006
更新日期:2007-02-01 00:00:00
abstract::1. Subdivided portions of the cut ventral root innervation of the soleus muscle were electrically stimulated in 14 anesthetized cats. The stimulus trains imposed on these nerves simulated the recruitment and rate-modulation patterns of single motor units recorded during stretch-reflex responses in decerebrate preparat...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1982.47.5.797
更新日期:1982-05-01 00:00:00
abstract::We used laser scanning photostimulation through a focused UV laser of caged glutamate in an in vitro slice preparation through the rat's somatosensory thalamus to study topography and connectivity between the thalamic reticular nucleus and ventral posterior lateral nucleus. This enabled us to focally stimulate the som...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00206.2005
更新日期:2005-10-01 00:00:00
abstract::We attempted to analyze the nature of premovement activity of neurons in medial motor areas [supplementary motor area (SMA) and pre-SMA] from a perspective of coding multiple movements. Monkeys were trained to perform a series of two movements with an intervening delay: supination or pronation with either forearm. Mov...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.90636.2008
更新日期:2009-04-01 00:00:00
abstract::Macaque SEF neurons encode object-centered directions of eye movements regardless of the visual attributes of instructional cues. Neurons in the supplementary eye field (SEF) of the macaque monkey exhibit object-centered direction selectivity in the context of a task in which a spot flashed on the right or left end of...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1999.81.5.2340
更新日期:1999-05-01 00:00:00
abstract::Response adaptation is the change of the firing rate of neurons induced by a preceding stimulus. It can be found in many sensory systems and throughout the auditory pathway. We investigated response adaptation in the external nucleus of the inferior colliculus (ICX) of barn owls ( Tyto furcata), a nocturnal bird of pr...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00769.2017
更新日期:2018-03-01 00:00:00
abstract::Although frequency-dependent short-term presynaptic plasticity has been of long-standing interest, most studies have emphasized modulation of the synchronous, phasic component of transmitter release, most evident with a single or a few presynaptic stimuli. Asynchronous transmitter release, vesicle fusion not closely t...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00683.2009
更新日期:2010-01-01 00:00:00
abstract::Regeneration of a cut muscle nerve fails to restore the stretch reflex, and the companion paper to this article [Alvarez FJ, Titus-Mitchell HE, Bullinger KL, Kraszpulski M, Nardelli P, Cope TC. J Neurophysiol (August 10, 2011). doi:10.1152/jn.01095.2010] suggests an important central contribution from substantial and ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01097.2010
更新日期:2011-11-01 00:00:00
abstract::1. Adult rats and rats with a postnatal age of 3-29 days (PN 3-29) were used for the preparation of in vitro slices of the frontal neocortex. Epileptiform activity was induced by bath application of the gamma-aminobutyric acid-A (GABAA) receptor antagonists bicuculline or picrotoxin. 2. The voltage-sensitive dye RH 41...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1994.72.4.1756
更新日期:1994-10-01 00:00:00
abstract::Noninvasive alternating current stimulation can induce vision restoration in patients with chronic optic nerve damage and results in electroencephalogram (EEG) aftereffects. To better understand the mechanisms of action, we studied such EEG "aftereffects" of transcorneal alternating current stimulation (tACS) at the c...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00341.2012
更新日期:2012-11-01 00:00:00
abstract::The dorsolateral pontine nucleus (DLPN) and nucleus reticularis tegmenti pontis (NRTP) comprise obligatory links in the cortico-ponto-cerebellar system supporting smooth pursuit eye movements. We examined the response properties of DLPN and rNRTP neurons during step-ramp smooth pursuit of a small target moving across ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00588.2004
更新日期:2005-01-01 00:00:00
abstract::Histamine is a known secretagogue in adrenal chromaffin cells. Activation of G-protein linked H(1) receptors stimulates phospholipase C, which generates inositol trisphosphate leading to release of intracellular calcium stores and stimulation of calcium influx through store operated and other channels. This calcium le...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2000.83.3.1435
更新日期:2000-03-01 00:00:00
abstract::Dopamine neurons in freely moving rats often fire behaviorally relevant high-frequency bursts, but depolarization block limits the maximum steady firing rate of dopamine neurons in vitro to ∼10 Hz. Using a reduced model that faithfully reproduces the sodium current measured in these neurons, we show that adding an add...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00578.2014
更新日期:2014-12-01 00:00:00
abstract::Ipsilaterally projecting spinal excitatory interneurons (EINs) generate the hemisegmental rhythmic locomotor activity in lamprey, while the commissural interneurons ensure proper left-right alternation. 5-HT is a potent modulator of the locomotor rhythm and is endogenously released from the spinal cord during fictive ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00309.2006
更新日期:2006-08-01 00:00:00
abstract::Stress-related alterations to the induction of hippocampal synaptic plasticity have been implicated in certain forms of psychiatric disorders. However, relatively little is known about such changes in other psychiatric disorders-related structures. We tested this possibility in one of such structures, the nucleus accu...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00895.2002
更新日期:2003-11-01 00:00:00
abstract::Mechanoreceptors of the crayfish tail fan have peripheral somata and send their axons to the last (sixth) abdominal ganglion via five bilateral pairs of nerve roots (R1-R5). Comparisons were made between normal crayfish and regenerate preparations in which R4 had been cut and directed back to an extensively denervated...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1985.54.2.385
更新日期:1985-08-01 00:00:00
abstract::1. The torque and electromyographic (EMG) responses to stretch of the first dorsal interosseous muscle (externally imposed joint rotation) were recorded in five normal human subjects. The total measured stiffness was decomposed into three individual stiffness components; passive, intrinsic, and reflex. 2. The passive ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1990.64.1.105
更新日期:1990-07-01 00:00:00
abstract::1. Responses of primary sensory neurons to substance P applications by perfusion were studied with intracellular recording techniques in in vitro slice preparations of trigeminal root ganglia (guinea pigs). Application of substance P in micromolar doses produced reversible depolarizations of 2-47 mV in 48 out of 64 ne...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1990.64.1.273
更新日期:1990-07-01 00:00:00
abstract::The exercise pressor reflex (EPR) is generated by group III and IV muscle afferents during exercise to increase cardiovascular function. Muscle contraction is triggered by ACh, which is metabolized into choline that could serve as a signal of exercise-induced activity. We demonstrate that ACh can induce current in mus...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00035.2014
更新日期:2014-09-15 00:00:00
abstract::The mouse is an important model system for understanding the molecular basis of neuronal signaling and diseases of synaptic communication. However, the best-characterized retinal ribbon-style synapses are those of nonmammalian vertebrates. To remedy this situation, we asked whether it would be feasible to track synapt...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00688.2006
更新日期:2006-11-01 00:00:00
abstract::The structural elements of the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) signaling pathway have been described in the vestibular peripheral system. However, the functions of NO in the vestibular endorgans are still not clear. We evaluated the action of NO on the Ca(2+) currents in hair cells isolated from ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00849.2006
更新日期:2007-02-01 00:00:00
abstract::In recent years, electroencephalography and magnetoencephalography (MEG) have both been used to investigate the response in human auditory cortex to musical sounds that are perceived as consonant or dissonant. These studies have typically focused on the transient components of the physiological activity at sound onset...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00876.2018
更新日期:2020-04-01 00:00:00
abstract::Retinal degeneration (rd) leads to progressive photoreceptor cell death, resulting in vision loss. Stimulation of the inner-retinal neurons by neuroprosthetic implants is one of the clinically approved vision-restoration strategies, providing basic visual percepts to blind patients. However, little is understood as to...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01095.2015
更新日期:2016-10-01 00:00:00
abstract::The inferior temporal cortex (IT) of the monkey, a final stage in the ventral visual pathway, has been known to process information on two-dimensional (2-D) shape, color, and texture. On the other hand, the dorsal visual pathway leading to the posterior parietal cortex has been known to process information on location...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2000.84.1.120
更新日期:2000-07-01 00:00:00
abstract::The primary motor cortex (MI) commands motor output after kinematics are planned from goals, thought to occur in a larger premotor network. However, there is a growing body of evidence that MI is involved in processes beyond action generation, and neuronal subpopulations may perform computations related to cue-to-acti...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00274.2013
更新日期:2014-01-01 00:00:00
abstract::Muscles paralyzed by chronic (>1 yr) spinal cord injury fatigue readily. Our aim was to evaluate whether the fatigability of paralyzed thenar muscles (n = 10) could be reduced by the repeated delivery of variable versus constant frequency pulse trains. Fatigue was induced in four ways. Intermittent supramaximal median...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01002.2002
更新日期:2003-04-01 00:00:00