Eye movements in response to dichoptic motion: evidence for a parallel-hierarchical structure of visual motion processing in primates.

Abstract:

:Brief movements of a large-field visual stimulus elicit short-latency tracking eye movements termed "ocular following responses" (OFRs). To address the question of whether OFRs can be elicited by purely binocular motion signals in the absence of monocular motion cues, we measured OFRs from monkeys using dichoptic motion stimuli, the monocular inputs of which were flickering gratings in spatiotemporal quadrature, and compared them with OFRs to standard motion stimuli including monocular motion cues. Dichoptic motion did elicit OFRs, although with longer latencies and smaller amplitudes. In contrast to these findings, we observed that other types of motion stimuli categorized as non-first-order motion, which is undetectable by detectors for standard luminance-defined (first-order) motion, did not elicit OFRs, although they did evoke the sensation of motion. These results indicate that OFRs can be driven solely by cortical visual motion processing after binocular integration, which is distinct from the process incorporating non-first-order motion for elaborated motion perception. To explore the nature of dichoptic motion processing in terms of interaction with monocular motion processing, we further recorded OFRs from both humans and monkeys using our novel motion stimuli, the monocular and dichoptic motion signals of which move in opposite directions with a variable motion intensity ratio. We found that monocular and dichoptic motion signals are processed in parallel to elicit OFRs, rather than suppressing each other in a winner-take-all fashion, and the results were consistent across the species.

journal_name

J Neurophysiol

authors

Hayashi R,Miura K,Tabata H,Kawano K

doi

10.1152/jn.01316.2007

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

2329-46

issue

5

eissn

0022-3077

issn

1522-1598

pii

01316.2007

journal_volume

99

pub_type

杂志文章
  • Permeation properties of the hair cell mechanotransducer channel provide insight into its molecular structure.

    abstract::Mechanoelectric transducer (MET) channels, located near stereocilia tips, are opened by deflecting the hair bundle of sensory hair cells. Defects in this process result in deafness. Despite this critical function, the molecular identity of MET channels remains a mystery. Inherent channel properties, particularly those...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01178.2011

    authors: Pan B,Waguespack J,Schnee ME,LeBlanc C,Ricci AJ

    更新日期:2012-05-01 00:00:00

  • Functional properties of neurons in the primate tongue primary motor cortex during swallowing.

    abstract::Recent studies conducted in our laboratory have suggested that the tongue primary motor cortex (i.e., tongue-MI) plays a critical role in the control of voluntary tongue movements in the primate. However, the possible involvement of tongue-MI in semiautomatic tongue movements, such as those in swallowing, remains unkn...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1997.78.3.1516

    authors: Martin RE,Murray GM,Kemppainen P,Masuda Y,Sessle BJ

    更新日期:1997-09-01 00:00:00

  • Cutaneous masking. II. Geometry of excitatory andinhibitory receptive fields of single units in somatosensory cortex of the cat.

    abstract::1. The responses of single neurons in the primary somatosensory cortex of the cat to brief air-pulse stimuli were quantitatively examined. These controlled natural stimuli activated almost exclusively rapidly adapting hair units which, on systematic movement of the stimulus through the receptive field, gave unit-respo...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1979.42.4.1061

    authors: Laskin SE,Spencer WA

    更新日期:1979-07-01 00:00:00

  • Temporal representation of iterated rippled noise as a function of delay and sound level in the ventral cochlear nucleus.

    abstract::The discharge patterns of single units in the ventral cochlear nucleus (VCN) of anesthetized guinea pigs were examined in response to iterated rippled noise (IRN) as a function of the IRN delay (which determines the IRN pitch) and the IRN sound level. Delays were varied over five octaves in half-octave steps, and soun...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2001.85.3.1206

    authors: Wiegrebe L,Winter IM

    更新日期:2001-03-01 00:00:00

  • Electrical feedback in the cone pedicle: a computational analysis.

    abstract::One of the fundamental principles of neuroscience is that direct electrical interactions between neurons are not possible without specialized electrical contacts, gap junctions, because the transmembrane resistance of neurons is typically much higher than the resistance of the adjacent extracellular space. However it ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00098.2005

    authors: Dmitriev AV,Mangel SC

    更新日期:2006-03-01 00:00:00

  • Role of GABA in shaping frequency tuning and creating FM sweep selectivity in the inferior colliculus.

    abstract::1. We examined the role of gamma-aminobutyric acid (GABA)-mediated inhibition in shaping excitatory tuning curves and creating selectivity for frequency-modulated (FM) sweeps in 29 neurons in the central nucleus of the inferior colliculus (ICC) of the pallid bat, with the use of single-unit recording coupled with the ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1996.76.2.1059

    authors: Fuzessery ZM,Hall JC

    更新日期:1996-08-01 00:00:00

  • Behavioral thermosensitivity after lesions of thalamic target areas of a thermosensory spinothalamic pathway in the cat.

    abstract::The ability of 17 cats to discriminate floor temperatures 2-4 degrees C below the ambient temperature was tested before and after unilateral electrolytic thalamic lesions. The lesions were made contralateral to the paws showing better performance in the temperature discrimination task. They were aimed at one or more o...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1999.82.2.611

    authors: Norrsell U,Craig AD

    更新日期:1999-08-01 00:00:00

  • Whole-hand water flow stimulation increases motor cortical excitability: a study of transcranial magnetic stimulation and movement-related cortical potentials.

    abstract::Previous studies examining the influence of afferent stimulation on corticospinal excitability have demonstrated that the intensity of afferent stimulation and the nature of the afferents targeted (cutaneous/proprioceptive) determine the effects. In this study, we assessed the effects of whole-hand water immersion (WI...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00161.2014

    authors: Sato D,Yamashiro K,Onishi H,Yasuhiro B,Shimoyama Y,Maruyama A

    更新日期:2015-02-01 00:00:00

  • Opposing mechanisms underlying differential changes in brain oxygen and temperature induced by intravenous morphine.

    abstract::Morphine remains widely used in clinical settings due to its potent analgesic properties. However, one of the gravest risks of all opioids is their ability to induce respiratory depression and subsequent brain hypoxia that can lead to coma and death. Due to these life-threatening effects, our goal was to examine the e...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00445.2018

    authors: Solis E Jr,Afzal A,Kiyatkin EA

    更新日期:2018-11-01 00:00:00

  • Neural modulation of gut motility by myomodulin peptides and acetylcholine in the snail Lymnaea.

    abstract::Families of peptide neuromodulators are believed to play important roles in neural networks that control behaviors. Here, we investigate the expression and role of one such group of modulators, the myomodulins, in the feeding system of Lymnaea stagnalis. Using a combination of in situ hybridization and antibody staini...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1998.79.5.2460

    authors: Perry SJ,Straub VA,Kemenes G,Santama N,Worster BM,Burke JF,Benjamin PR

    更新日期:1998-05-01 00:00:00

  • Physiological studies of cutaneous inputs to dorsal horn laminae I-IV of adult chickens.

    abstract::1. The dorsal horn (DH) of chickens exhibits a novel pattern of cytoarchitectonic lamination among vertebrates, whereby lamina III lies medial, rather than ventral, to lamina II. Indeed, cutaneous nerves labeled with horseradish peroxidase (HRP) form two separate projections across the mediolateral axis of the superfi...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.67.2.241

    authors: Woodbury CJ

    更新日期:1992-02-01 00:00:00

  • The small fiber neuropathy NaV1.7 I228M mutation: impaired neurite integrity via bioenergetic and mitotoxic mechanisms, and protection by dexpramipexole.

    abstract::Gain-of-function variants in voltage-gated sodium channel NaV1.7 that increase firing frequency and spontaneous firing of dorsal root ganglion (DRG) neurons have recently been identified in 5-10% of patients with idiopathic small fiber neuropathy (I-SFN). Our previous in vitro observations suggest that enhanced sodium...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00360.2019

    authors: Lee SI,Hoeijmakers JGJ,Faber CG,Merkies ISJ,Lauria G,Waxman SG

    更新日期:2020-02-01 00:00:00

  • Evidence for synergy between saccades and smooth pursuit during transient target disappearance.

    abstract::Visual tracking of moving objects requires prediction to compensate for visual delays and minimize mismatches between eye and target position and velocity. In everyday life, objects often disappear behind an occluder, and prediction is required to align eye and target at reappearance. Earlier studies investigating eye...

    journal_title:Journal of neurophysiology

    pub_type: 临床试验,杂志文章

    doi:10.1152/jn.00596.2005

    authors: Orban de Xivry JJ,Bennett SJ,Lefèvre P,Barnes GR

    更新日期:2006-01-01 00:00:00

  • Inhibition and facilitation of different nocifensor reflexes by spatially remote noxious stimuli.

    abstract::1. Noxious stimuli have been shown to produce a diffuse inhibition of nociresponsive neurons in the spinal and trigeminal dorsal horns. The present study sought to extend these electrophysiological studies of diffuse noxious inhibitory controls (DNIC) by determining the effect of a spatially remote noxious stimulus on...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1994.72.3.1152

    authors: Morgan MM,Heinricher MM,Fields HL

    更新日期:1994-09-01 00:00:00

  • Rapid visuomotor feedback gains are tuned to the task dynamics.

    abstract::Adaptation to novel dynamics requires learning a motor memory, or a new pattern of predictive feedforward motor commands. Recently, we demonstrated the upregulation of rapid visuomotor feedback gains early in curl force field learning, which decrease once a predictive motor memory is learned. However, even after learn...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00748.2016

    authors: Franklin S,Wolpert DM,Franklin DW

    更新日期:2017-11-01 00:00:00

  • Optogenetic fMRI sheds light on the neural basis of the BOLD signal.

    abstract::Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) is widely used as a measure of neuronal activity, despite an incomplete understanding of the hemodynamic and neural bases for BOLD signals. Recent work by Lee and colleagues investigated whether activating genetically specified neuro...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章,评审

    doi:10.1152/jn.00535.2010

    authors: Palmer HS

    更新日期:2010-10-01 00:00:00

  • Effects of image motion in the dorsal premotor cortex during planning of an arm movement.

    abstract::This study examined whether neuronal activity in the dorsal premotor cortex (PMd) covaries with image motion or actual movement of the arm while planning a target-capturing task when the motor task is guided by an image of the moving arm. For this purpose, we trained a monkey to capture a target on a video screen with...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2002.88.4.2167

    authors: Ochiai T,Mushiake H,Tanji J

    更新日期:2002-10-01 00:00:00

  • The spinal control of locomotion and step-to-step variability in left-right symmetry from slow to moderate speeds.

    abstract::When speed changes during locomotion, both temporal and spatial parameters of the pattern must adjust. Moreover, at slow speeds the step-to-step pattern becomes increasingly variable. The objectives of the present study were to assess if the spinal locomotor network adjusts both temporal and spatial parameters from sl...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00419.2015

    authors: Dambreville C,Labarre A,Thibaudier Y,Hurteau MF,Frigon A

    更新日期:2015-08-01 00:00:00

  • Alternate leg movement amplifies locomotor-like muscle activity in spinal cord injured persons.

    abstract::It is now well recognized that muscle activity can be induced even in the paralyzed lower limb muscles of persons with spinal cord injury (SCI) by imposing locomotion-like movements on both of their legs. Although the significant role of the afferent input related to hip joint movement and body load has been emphasize...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00817.2004

    authors: Kawashima N,Nozaki D,Abe MO,Akai M,Nakazawa K

    更新日期:2005-02-01 00:00:00

  • The raccoon lateral cervical nucleus: a single-unit analysis.

    abstract::1. Properties of 90 lateral cervical nucleus (LCN) neurons responsive to light tactile stimulation of ipsilateral body surfaces were examined in pentobarbital sodium-anesthetized raccoons. Peripheral receptive fields (RFs) of 60 of these lay totally or partially on glabrous skin of the forepaw. There were 71 neurons a...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1991.65.6.1411

    authors: Simone DA,Pubols BH Jr

    更新日期:1991-06-01 00:00:00

  • Responses of reticulospinal neurons in intact lamprey to vestibular and visual inputs.

    abstract::A lamprey maintains the dorsal-side-up orientation due to the activity of postural control system driven by vestibular input. Visual input can affect the body orientation: illumination of one eye evokes ipsilateral roll tilt. An important element of the postural network is the reticulospinal (RS) neurons transmitting ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2000.83.2.864

    authors: Deliagina TG,Fagerstedt P

    更新日期:2000-02-01 00:00:00

  • Effects of brain stem parabrachial activation on receptive field properties of cells in the cat's lateral geniculate nucleus.

    abstract::1. The lateral geniculate nucleus is the primary thalamic relay for the transfer of retinal signals to the visual cortex. Geniculate cells are heavily innervated from nonretinal sources, and these modify retinogeniculate transmission. A major ascending projection to the lateral geniculate nucleus arises from cholinerg...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1995.73.6.2428

    authors: Uhlrich DJ,Tamamaki N,Murphy PC,Sherman SM

    更新日期:1995-06-01 00:00:00

  • Modeling activity-dependent changes of axonal spike conduction in primary afferent C-nociceptors.

    abstract::Action potential initiation and conduction along peripheral axons is a dynamic process that displays pronounced activity dependence. In patients with neuropathic pain, differences in the modulation of axonal conduction velocity by activity suggest that this property may provide insight into some of the pathomechanisms...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00777.2012

    authors: Tigerholm J,Petersson ME,Obreja O,Lampert A,Carr R,Schmelz M,Fransén E

    更新日期:2014-05-01 00:00:00

  • Motor cost affects the decision of when to shift gaze for guiding movement.

    abstract::Frequent gait modifications are often required to navigate our world. These can involve long or wide steps or changes in direction. People generally prefer to minimize the motor cost (or effort) of a movement, although with changes in gait this is not always possible. The decision of when and where to shift gaze is cr...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00027.2019

    authors: Domínguez-Zamora FJ,Marigold DS

    更新日期:2019-07-01 00:00:00

  • Effects of impulse frequency, PTP, and temperature on responses elicited in large populations of motoneurons by impulses in single Ia-fibers.

    abstract::Excitatory postsynaptic potentials (EPSPs) were evoked in large populations of motoneurons by impulses in single Ia- and group II fibers and recorded from L7 and S1 ventral roots by means of a sucrose-gap technique and spike-triggered averaging, as previously described (33, 34). Factors known to influence conduction a...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1983.50.5.1045

    authors: Lüscher H,Ruenzel PW,Henneman E

    更新日期:1983-11-01 00:00:00

  • Propagation of spindle waves in a thalamic slice model.

    abstract::1. We study the propagation and dynamics of spindle waves in thalamic slices by developing and analyzing a model of reciprocally coupled populations of excitatory thalamocortical (TC) neurons and inhibitory thalamic reticular (RE) neurons. 2. Each TC neuron has three intrinsic ionic currents: a low-threshold T-type Ca...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1996.75.2.750

    authors: Golomb D,Wang XJ,Rinzel J

    更新日期:1996-02-01 00:00:00

  • Spatial structure of multiwhisker receptive fields in the barrel cortex is stimulus dependent.

    abstract::The tactile sensations mediated by the whisker-trigeminal system allow rodents to efficiently detect and discriminate objects. These capabilities rely strongly on the temporal and spatial structure of whisker deflections. Subthreshold but also spiking receptive fields in the barrel cortex encompass a large number of v...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00044.2011

    authors: Le Cam J,Estebanez L,Jacob V,Shulz DE

    更新日期:2011-08-01 00:00:00

  • Activity-dependent modulation of glutamatergic signaling in the developing rat dorsal horn by early tissue injury.

    abstract::Tissue injury in early life can produce distinctive effects on pain processing, but little is known about the underlying neural mechanisms. Neonatal inflammation modulates excitatory synapses in spinal nociceptive circuits, but it is unclear whether this results directly from altered afferent input. Here we investigat...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00520.2009

    authors: Li J,Walker SM,Fitzgerald M,Baccei ML

    更新日期:2009-10-01 00:00:00

  • Hyperactivity in the medial olivocochlear efferent system is a common feature of tinnitus and hyperacusis in humans.

    abstract::Tinnitus and hyperacusis are common, burdensome sources of morbidity with a high rate of co-occurrence. Knudson et al. (J Neurophysiol 112: 3197-3208, 2014) demonstrated that efferent suppression of cochlear activity by the medial olivocochlear system is enhanced in individuals with tinnitus and/or hyperacusis. Their ...

    journal_title:Journal of neurophysiology

    pub_type: 评论,杂志文章

    doi:10.1152/jn.00948.2014

    authors: Sturm JJ,Weisz CJ

    更新日期:2015-11-01 00:00:00

  • Using spatiotemporal correlations to learn topographic maps for invariant object recognition.

    abstract::The retinal image of visual objects can vary drastically with changes of viewing angle. Nevertheless, our visual system is capable of recognizing objects fairly invariant of viewing angle. Under natural viewing conditions, different views of the same object tend to occur in temporal proximity, thereby generating tempo...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.90651.2008

    authors: Michler F,Eckhorn R,Wachtler T

    更新日期:2009-08-01 00:00:00