Comparative proteomic analysis of radiation-induced changes in mouse lung: fibrosis-sensitive and -resistant strains.

abstract：:Tissue-incorporated radionuclides impart radiation energy over extended periods of time depending on their effective half-lives. The capacity of vitamin A dissolved in soybean oil to protect against the biological effects caused by internal radionuclides is investigated. The radiochemicals examined are DNA-binding 125...

journal_title：Radiation research

authors： Harapanhalli RS,Narra VR,Yaghmai V,Azure MT,Goddu SM,Howell RW,Rao DV

更新日期：1994-07-01 00:00:00

abstract：:Many studies have demonstrated the effect of oncogene transfection on the radiation sensitivity of primary rat embryo fibroblasts. Our results indicate that transformation by H-ras plus v-myc oncogenes confers radiation resistance to a much greater extent than transformation by either gene alone. We have further shown...

journal_title：Radiation research

authors： Bernhard EJ,McKenna WG,Muschel RJ

更新日期：1994-04-01 00:00:00

abstract：:Radiation exposure causes DNA breaks leading to structural chromosome aberrations that can be carcinogenic. Lifetime cancer risks are elevated in irradiated children compared to similarly exposed adults. To determine the extent to which age influences the frequency and types of chromosome damage in response to ionizin...

journal_title：Radiation research

authors： Bakhmutsky MV,Joiner MC,Jones TB,Tucker JD

更新日期：2014-06-01 00:00:00

abstract：:Cellular and molecular repair was studied at 23 degrees C using split-dose recovery and alkaline elution techniques, respectively, as a function of cellular oxygen and nutrient conditions. Hypoxic cells (0.001% O2) in full medium showed a partial reduction in the level of sublethal damage (SLD) repair relative to aera...

journal_title：Radiation research

authors： Spiro IJ,Kennedy KA,Stickler R,Ling CC

更新日期：1985-01-01 00:00:00

abstract：:These studies were carried out to examine the capacity of alpha-difluoromethylornithine (DFMO) to modulate cell proliferation and apoptosis in cells of squamous cell carcinomas (SCCs) of the head and neck. Exposure of cells to DFMO (5 mM for 48 h) depleted intracellular putrescine and spermidine levels (greater than 5...

journal_title：Radiation research

authors： Bock JM,Pickart MA,Pink JJ,Harari PM

更新日期：1999-12-01 00:00:00

abstract：:We have previously observed time- and dose-dependent increases in matrix metalloproteinase 2 (Mmp2) protein levels in rat tubule epithelial cells (NRK52E) after irradiation. However, the mechanism(s) involved remains unclear. In the present study, irradiating NRK52E cells with 0-20 Gy gamma rays was associated with ti...

journal_title：Radiation research

authors： Zhao W,Goswami PC,Robbins ME

更新日期：2004-04-01 00:00:00

abstract：:Bcl-X(S) is a pro-apoptosis member of the Bcl2 family that has been shown to induce cell death and enhance chemosensitivity. We have investigated the effect of Bcl-X(S) overexpression on radiation sensitivity. Using a tetracycline-repressible system, we found that removal of tetracycline for 16 h induced Bcl-X(S) and ...

journal_title：Radiation research

authors： Morgan MA,Poynter JN,Maybaum J,Lawrence TS

更新日期：2004-05-01 00:00:00

abstract：:Deep underground laboratories (DULs) were originally created to host particle, astroparticle or nuclear physics experiments requiring a low-background environment with vastly reduced levels of cosmic-ray particle interference. More recently, the range of science projects requiring an underground experiment site has gr...

journal_title：Radiation research

authors： Morciano P,Cipressa F,Porrazzo A,Esposito G,Tabocchini MA,Cenci G

更新日期：2018-09-01 00:00:00

abstract：:As part of a long-term study of the effects of irradiation during development, prenatal and early neonatal mortality were evaluated for beagles exposed in utero at 8 days postcoitus (dpc), 28 dpc, 55 dpc, or 2 days postpartum. Mean doses used were 0,0.16, or 0.83 Gy. A decrease in whelping rates was observed for femal...

journal_title：Radiation research

authors： Angleton GM,Benjamin SA,Lee AC

更新日期：1988-07-01 00:00:00

abstract：:The level and distribution of radiofrequency energy absorbed in a child's head during the use of a mobile phone compared to those in an adult head has been a controversial issue in recent years. It has been suggested that existing methods that are used to determine specific absorption rate (SAR) and assess compliance ...

journal_title：Radiation research

authors： Bit-Babik G,Guy AW,Chou CK,Faraone A,Kanda M,Gessner A,Wang J,Fujiwara O

更新日期：2005-05-01 00:00:00

abstract：:We have previously shown significant pathology in the heart and kidney of murine hematopoietic-acute radiation syndrome (H-ARS) survivors of 8.7-9.0 Gy total-body irradiation (TBI). The goal of this study was to determine temporal relationships in the development of vasculopathy and the progression of renal and cardio...

journal_title：Radiation research

authors： Unthank JL,Ortiz M,Trivedi H,Pelus LM,Sampson CH,Sellamuthu R,Fisher A,Chua HL,Plett A,Orschell CM,Cohen EP,Miller SJ

更新日期：2019-05-01 00:00:00

abstract：:Diethylenetriaminepentaacetic acid (DTPA) is currently still the only known chelating drug that can be used for decorporation of internalized plutonium (Pu) and americium (Am). It is generally assumed that chelation occurs only in biological fluids, thus preventing Pu/Am deposition in target tissues. We postulate that...

journal_title：Radiation research

authors： Grémy O,Laurent D,Coudert S,Griffiths NM,Miccoli L

更新日期：2016-06-01 00:00:00

abstract：:The efficacy of photodynamic therapy is dependent upon the optical dose rate or upon the fractionation schedule on the light. These effects are thought to be limited by the time required for oxygen diffusion from the capillaries, since this therapy can consume oxygen faster than it can be supplied to tissues distant f...

journal_title：Radiation research

authors： Pogue BW,Hasan T

更新日期：1997-05-01 00:00:00

abstract：:New Zealand rabbits, fasted for 12 hours, were subjected to 500 rads of whole-body irradiation. K+-palmitate-1-14C oxidation was assayed with the 600 X g supernatant of thymus and liver homogenates, in the presence of ATP, at various time intervals from irradiation. For a period of 24 hours following irradiation, oxid...

journal_title：Radiation research

authors： Miras CJ,Mantzos JD,Legakis NJ,Levis GM

更新日期：1968-11-01 00:00:00

abstract：:Tritium that is bound to organic molecules is of special risk for living systems, in particular when such molecules are components of the cell nucleus. Therefore, [3H]thymidine and [3H]arginine were studied for radiotoxicity in early mammalian embryo development. Starting with the two-cell stage, mouse embryos were in...

journal_title：Radiation research

authors： Müller WU,Streffer C,Molls M,Glück L

更新日期：1987-05-01 00:00:00

abstract：:Chinese hamster ovary cells were irradiated with 250 kVp X rays and analyzed for the presence of DNA double-strand breaks using either polycarbonate filter elution or pulsed-field agarose gel electrophoresis at neutral pH. Reduction in DNA length detected by filter elution was produced as a nonlinear function of incre...

journal_title：Radiation research

authors： Warters RL,Lyons BW

更新日期：1990-12-01 00:00:00

abstract：:The hypothesis of boron neutron capture therapy (BNCT) research has been that the short-range, high-linear energy transfer radiation produced by the capture of thermal neutrons by (10)B will potentially control tumor and spare normal tissue only if the boron compound selectively targets tumor tissue within the treatme...

journal_title：Radiation research

authors： Trivillin VA,Heber EM,Nigg DW,Itoiz ME,Calzetta O,Blaumann H,Longhino J,Schwint AE

更新日期：2006-08-01 00:00:00

abstract：:To investigate whether exposure to atomic bomb radiation altered the prevalence of hepatitis C virus (HCV) infection or accelerated the progress toward chronic hepatitis after HCV infection, the seropositivity of antibody to hepatitis C virus (anti-HCV) was determined for 6,121 participants in the Adult Health Study o...

journal_title：Radiation research

authors： Fujiwara S,Kusumi S,Cologne J,Akahoshi M,Kodama K,Yoshizawa H

更新日期：2000-07-01 00:00:00

abstract：:Information on early internal radiation doses in Fukushima after the nuclear power plant accident on March 11, 2011, is quite limited due to initial organizational difficulties, high background radiation and contamination of radiation measuring devices. In Nagasaki, approximately 1,200 km away from Fukushima, the inte...

journal_title：Radiation research

authors： Matsuda N,Kumagai A,Ohtsuru A,Morita N,Miura M,Yoshida M,Kudo T,Takamura N,Yamashita S

更新日期：2013-06-01 00:00:00

abstract：:The risk of a radiological or nuclear public health emergency is a major growing concern of the U.S. government. To address a potential incident and ensure that the government is prepared to respond to any subsequent civilian or military casualties, the U.S. Department of Health and Human Services and the Department o...

journal_title：Radiation research

authors： DiCarlo AL,Cassatt DR,Dowling WE,Esker JL,Hewitt JA,Selivanova O,Williams MS,Price PW

更新日期：2018-12-01 00:00:00

abstract：:Octacalcium phosphate (OCP) {Ca8H2(PO4)6×5H2O] has attracted increasing attention over the last decade as a transient intermediate to the biogenic apatite for bone engineering and in studies involving the processes of pathological calcification. In this work, OCP powders obtained by hydrolysis of dicalcium phosphate d...

journal_title：Radiation research

authors： Shurtakova DV,Yavkin BV,Mamin GV,Orlinskii SB,Sirotinkin VP,Fedotov AY,Shinkarev A,Antuzevics A,Smirnov IV,Tovtin VI,Starostin EE,Gafurov MR,Komlev VS

更新日期：2020-12-10 00:00:00

abstract：:Through a detailed study of cell cycle progression, protein expression, and kinase activity in gamma-irradiated synchronized cultures of human skin fibroblasts, distinct mechanisms of initiation and maintenance of G2-phase and subsequent G1-phase arrests have been elucidated. Normal and E6-expressing fibroblasts were ...

journal_title：Radiation research

authors： DeSimone JN,Bengtsson U,Wang X,Lao XY,Redpath JL,Stanbridge EJ

更新日期：2003-01-01 00:00:00

abstract：:After exposure to 10 or 20 J/m2 UVC light, cells of the UMN-PIE-1181 line, an embryonic cell line derived from the Indian meal moth, Plodia interpunctella, exhibited a rapid and prolonged depression in the rate of incorporation of [3H]thymidine, whereas cells of the TN-368 line, an ovarian cell line derived from Trich...

journal_title：Radiation research

authors： Styer SC,Griffiths TD

更新日期：1992-04-01 00:00:00

abstract：:We have examined the role of natural killer (NK) cells in situ in the recovery of marrow hematopoiesis in B6D2F1 mice receiving various doses of total-body irradiation (TBI) as a well-characterized model for treatment-induced myelosuppression. Applying an in situ cytotoxic approach for ablating NK 1.1 cells, we have d...

journal_title：Radiation research

authors： Pantel K,Boertman J,Nakeff A

更新日期：1990-05-01 00:00:00

abstract：:Experimental measurements of the radial restricted linear energy transfer (LETr) for alpha beams of 18.3 MeV/n in tissue-equivalent gas were presented. The radial dose distribution for the alpha beam was deduced from the restricted LET measurements. A differential W value for the alpha particle in the tissue-equivalen...

journal_title：Radiation research

authors： Kanai T,Kawachi K

更新日期：1987-12-01 00:00:00

abstract：:The effect of acute exposure to ultrawideband (UWB) electromagnetic radiation on the Primate Equilibrium Platform (PEP) task, where the monkey's task is to manipulate a joystick control to compensate for the random perturbations in the pitch plane that are generated by a computer at unpredictable intervals, was examin...

journal_title：Radiation research

authors： Sherry CJ,Blick DW,Walters TJ,Brown GC,Murphy MR

更新日期：1995-07-01 00:00:00

abstract：:The survival of synchronous G1 or asynchronous Chinese hamster ovary cells in vitro to heat treatment may depend on the cellular population density at the time of heating and/or as the cells are cultured after heating. The addition of lethally irradiated feeder cells may increase survival at 10(-3) by as much as 10- t...

journal_title：Radiation research

authors： Highfield DP,Holahan EV,Holahan PK,Dewey WC

更新日期：1984-01-01 00:00:00

abstract：:This paper evaluates the global vitamin D effective UV (UV(vitd)) irradiances under cloudy conditions at a subtropical, southern hemisphere site. The UV(vitd) irradiances were analyzed on a horizontal plane and sampled at 5-min intervals over 18 months so that a wide range of parameters including cloud conditions, sol...

journal_title：Radiation research

authors： Turnbull DJ,Parisi AV,Schouten PW

更新日期：2010-05-01 00:00:00

abstract：:We studied the role of cysteine as an intracellular radiation protector under conditions in which both oxygen and thiols were monitored at 37 degrees C. In HCT-116 human colon cancer cells, the intracellular cysteine content affects the radiation survival dramatically at intermediate oxygen levels, but not at zero or ...

journal_title：Radiation research

authors： Horan AD,Koch CJ

更新日期：2001-10-01 00:00:00

abstract：:The Radiological Research Accelerator Facility (RARAF) is in its 50th year of operation. It was commissioned on April 1, 1967 as a collaboration between the Radiological Research Laboratory (RRL) of Columbia University, and members of the Medical Research Center of Brookhaven National Laboratory (BNL). It was initiall...

journal_title：Radiation research

authors： Marino SA

更新日期：2017-04-01 00:00:00