Abstract：
:We report the effect of 250 mg of sodium thiopental on vascular tone at constant blood flow in 26 patients undergoing cardiopulmonary bypass while the ascending aorta was cross-clamped. Light anaesthesia was effected with fentanyl and enflurane, muscle relaxation with pancuronium. After a latent period of 10.5 +/- 0.7 s there was a hypertensive response of 9.8 +/- 0.5 s duration and of 21.4 +/- 1.7 mmHg (2.8 +/- 0.2 kPa) magnitude; this was followed by hypotension of 39.6 +/- 4.2 s duration and of 18.4 +/- 1.9 mmHg (2.4 +/- 0.3 kPa) magnitude. There was a statistically significant inverse correlation between the hypertension and body temperature (P = 0.005); the time to onset of hypertension correlated directly with pump volume (P = 0.001), weight of the patient (P = 0.03), and cross-clamp time before the drug was given (P = 0.002), and correlated inversely with the serum sodium concentration (P = 0.001). The duration of hypertension was inversely related to the plasma bicarbonate (P = 0.01) and body temperature (P = 0.04). The duration of hypotension was significantly longer in women (P = 0.0001) and was directly related to the duration of cross-clamping (P = 0.0007), to pH (P = 0.0016), and to PCO2 (P = 0.04). We speculate that thiopental induced the hypertensive response due to a potentiation of the vasoconstrictive (local) effect of norepinephrine, and induced the hypotensive response by a central nervous system effect. Thiopental had no apparent effect on venous tone.
journal_name
Acta Anaesthesiol Scandjournal_title
Acta anaesthesiologica Scandinavicaauthors
Pauca AL,Roy RCdoi
10.1111/j.1399-6576.1986.tb02475.xsubject
Has Abstractpub_date
1986-10-01 00:00:00pages
562-5issue
7eissn
0001-5172issn
1399-6576journal_volume
30pub_type
杂志文章abstract：:Non-steroidal anti-inflammatory drugs (NSAID) effectively reduce the need for opioid analgesia after various types of surgery. The efficacy of diclofenac and ketoprofen to relieve pain after maxillofacial surgery was compared in the present study. In a randomized and double-blind fashion, 90 ASA I-II patients (16-60 y...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1399-6576.1995.tb05599.x
更新日期：1995-01-01 00:00:00
abstract：BACKGROUND:To evaluate the effect of a recruitment maneuver (RM) with constant positive inspiratory pressure and high positive end-expiratory pressure (PEEP) on oxygenation and static compliance (Cs) in patients with severe acute respiratory distress syndrome (ARDS). METHODS:Eight patients with ARDS ventilated with lu...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.0001-5172.2004.0305.x
更新日期：2004-03-01 00:00:00
abstract：:We present the case of a parturient with moyamoya disease admitted to the hospital for elective cesarean section. Combined spinal and epidural technique was chosen because it allows better analgesia than epidural anesthesia and more hemodynamic stability than either general or spinal anesthesia. Ropivacaine was the lo...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1998.tb05388.x
更新日期：1998-10-01 00:00:00
abstract：BACKGROUND:To compare isoflurane anesthesia in patients with or without hyperbilirubinemia undergoing hepatobiliary surgery. METHODS:Forty-two patients with obstructive jaundice and 40 control patients with normal liver function scheduled for hepatobiliary surgery under isoflurane anesthesia were studied. Anesthesia w...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.2010.02222.x
更新日期：2010-08-01 00:00:00
abstract：:Forty-four children, ASA physical status I or II, aged 1.5-14 years and admitted for strabismus surgery, were studied. The study compared the postoperative condition after two different anesthesia methods. All children were premedicated with midazolam rectally, received glycopyrrolate i.v. and were then randomised to ...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1399-6576.1992.tb03448.x
更新日期：1992-02-01 00:00:00
abstract：BACKGROUND:Histamine receptors are involved in the development of inflammatory pain and hyperalgesia, and the use of antihistamines is advocated as an alternative for pain therapy and treatment of postoperative nausea and vomiting. We investigated the influence of timing of promethazine administration on postoperative ...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1399-6576.2004.00369.x
更新日期：2004-05-01 00:00:00
abstract：BACKGROUND:Various methods are used to reduce venous blood pressure in the hepato-splanchnic circulation, and hence minimise blood loss during liver surgery. Previous studies show that combination of vasopressin and nitroglycerin reduces portal pressure and flow in patients with portal hypertension, and in this study w...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aas.13117
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Previous studies have shown that ventilation-perfusion matching is improved in the prone as compared with that in the supine position. Regional differences in the regulation of vascular tone may explain this. We have recently demonstrated higher production of nitric oxide in dorsal compared with ventral huma...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.2009.02018.x
更新日期：2009-10-01 00:00:00
abstract：:Midazolam, a new water-soluble benzodiazepine, was compared with thiopentone as an induction agent prior to inhalational anaesthesia. Induction time, cardiovascular response and venous sequelae were studied in 100 healthy in-patients randomly divided into two groups. Midazolam proved to be a good alternative to thiope...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1984.tb02053.x
更新日期：1984-06-01 00:00:00
abstract：:During laparoscopic hepatic resection, an abrupt decrease in FE'CO(2) (from 28 mmHg to 9 mmHg) associated with near cardiac arrest occurred concomitantly with hepatic vein laceration and the use of an argon beam coagulator system. During venous gas embolism, transesophageal echocardiography (TEE) proved the transpulmo...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.2007.01361.x
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:We conducted a prospective observational survey of pregnant women with cardiac disease. The aim was to analyse and present the mode of delivery, outcome, and haemodynamic changes during a caesarean section under regional anaesthesia in women with cardiac disease. METHODS:All pregnant women with a cardiovasc...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.2009.02080.x
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:Morphine decreases gut peristalsis, and ketamine decreases morphine use after surgery, and does not slow peristalsis. Thus, the combination should result in faster return of bowel function after surgery than morphine alone. METHOD:A double-blind randomized controlled trial of saline vs. ketamine with intrav...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1399-6576.2007.01436.x
更新日期：2007-10-01 00:00:00
abstract：:Ventilatory responses to hypoxia (HVR) were investigated using poikilocapnic conditions (i.e. end-tidal CO2's allowed to seek it's own level) in 15 cardio-pulmonary healthy patients who were first studied awake and then at 0.85 MAC isoflurane. The influence of hypercapnia (HyperCapnic Ventilatory Response, HCVR) was a...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1994.tb03857.x
更新日期：1994-02-01 00:00:00
abstract：BACKGROUND:Anaphylactoid reactions in anaesthesia are rare and should ideally be investigated in specialist centres. At Gentofte University Hospital, we established such a centre in 1998 as a joint venture between the Departments of Anaesthesiology and Dermatology. We present the methodology, diagnostic algorithm and p...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1399-6576.2001.451005.x
更新日期：2001-11-01 00:00:00
abstract：:The ability of graduated compression elastic stockings to prevent hypotension during elective epidural caesarean section was evaluated. Twenty women were randomly assigned to two groups of ten, one group being fitted with the stockings. The incidence and degree of hypotension were the same in both groups. Graduated co...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1399-6576.1987.tb02548.x
更新日期：1987-04-01 00:00:00
abstract：:In order to evaluate the possible genotoxic effects of inhalation anaesthetics, the frequency of sister chromatid exchanges and chromosome aberrations was studied in peripheral lymphocytes of control subjects, operating room personnel and patients before and after inhalation anaesthesia during orthopaedic operations. ...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1982.tb01814.x
更新日期：1982-10-01 00:00:00
abstract：:When using deliberate haemodilution to a certain haematocrit value (Hct), the appropriate preoperative blood volume of the patient must be determined and matched with the transfusion volume at a certain blood loss. In order to facilitate such calculations a nomogram was constructed, aiming for a final Hct of 33%. Preo...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1986.tb02418.x
更新日期：1986-05-01 00:00:00
abstract：:A standardized rat endotoxin shock model was used to assess the differential effects of four commonly used anesthetics upon hemodynamics before and during endotoxin shock. Forty-nine male Sprague-Dawley rats weighing 307 +/- 4 g were divided into five groups:freely-moving conscious, enflurane (2%), isoflurane (1.4%), ...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1987.tb02619.x
更新日期：1987-08-01 00:00:00
abstract：BACKGROUND:We hypothesized that, compared with propofol, desflurane prolongs the antegrade accessory pathway effective refractory period (APERP) in children undergoing radiofrequency catheter ablation for Wolff-Parkinson-White (WPW) syndrome. METHODS:In this randomized crossover study, children aged 4.1-16.1 years und...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/aas.13023
更新日期：2018-02-01 00:00:00
abstract：:Standardized behavioural observations were used to establish the influence of the type of anaesthesia on the mental function and the subjective physical well-being in 60 patients, all men, following urological surgery. The patients were randomized to two groups, receiving spinal or general anaesthesia. For evaluation ...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1399-6576.1992.tb03531.x
更新日期：1992-10-01 00:00:00
abstract：:In order to antagonize immediate postoperative somnolence, 24 surgical patients were given a two-rate infusion of physostigmine, aiming at a constant plasma concentration in the range of 1 to 10 ng/ml. Plasma concentrations of physostigmine were determined during infusion and after infusion and the effects of physosti...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1989.tb02991.x
更新日期：1989-11-01 00:00:00
abstract：:Related values of cardiac output and hepatic blood flow were measured in eight premedicated (pethidine 10 mg/kg b.w.) dogs under varying depths of fluoromar anaesthesia. The measurements were first taken under basis anaesthesia with barbiturate (mebumal natrium 25 mg/kg b.w.) gallamine (80 mg)-N2O-O-O2 (ratio 2 to 1) ...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1976.tb05039.x
更新日期：1976-01-01 00:00:00
abstract：BACKGROUND:Research has shown that menstrual cycle phase may affect pain sensitivity. There is a lack of studies evaluating this effect on post-operative pain and analgesic needs. METHODS:In this prospective cohort study, we determined the effect of menstrual cycle phase on pain perception and analgesic requirements f...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.2012.02661.x
更新日期：2012-05-01 00:00:00
abstract：BACKGROUND:A controversy exists whether beneficial analgesic effects of epidural analgesia over intravenous analgesia influence the rate of post-operative complications and the length of hospital stay. There is some evidence that favours epidural analgesia following major surgery in high-risk patients. However, there i...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.2008.01734.x
更新日期：2008-11-01 00:00:00
abstract：BACKGROUND:Feed and swaddle is a technique in which an infant is fed and allowed to fall asleep to facilitate diagnostic imaging. This study reviews our experience and diagnostic success in premature and term infants up to 6 months old undergoing brain magnetic resonance imaging (MRI) using a feed and swaddle technique...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aas.13471
更新日期：2020-01-01 00:00:00
abstract：:The administration of glucocorticoids has been used to inhibit the cytokine production in patients undergoing cardiac surgery during cardiopulmonary bypass. In this case report the cytokine response in a 43-year-old man undergoing operation for an ACTH-producing lung tumor is presented. There had been clinical symptom...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1997.tb04686.x
更新日期：1997-02-01 00:00:00
abstract：BACKGROUND:Our aim in this observational study was to utilize ultrasound, as well as anatomic dissection, to document the frequency with which branches of the subclavian vessels are found in close association with the brachial plexus at the locations of supraclavicular and interscalene brachial plexus block. METHODS:U...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.2011.02528.x
更新日期：2011-11-01 00:00:00
abstract：:Aminophylline in a low dose has been shown to reverse diazepam sedation. The present investigation was performed as a double-blind study to compare the effects of aminophylline and enprofylline on deep diazepam sedation after surgery. Enprofylline is a xanthine derivative with anti-asthmatic effect but, in contrast to...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1399-6576.1986.tb02462.x
更新日期：1986-10-01 00:00:00
abstract：BACKGROUND:It has been speculated that epidural anaesthesia may induce bronchoconstriction via the mechanism of a sympathetic blockade. However, this hypothesis has not been confirmed by any experimental evidence. Therefore, we investigated the effects of high thoracic epidural anaesthesia with neural sympathetic block...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1998.tb05085.x
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:In comparison with bupivacaine, ropivacaine exhibits comparable anaesthetic effects but with less motor impairment and systemic toxicity. However, the analgesic potency may differ. For example, ropivacaine during obstetric epidural analgesia provides an approximately 40% lower analgesic potency than bupivaca...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1399-6576.2006.01259.x
更新日期：2007-03-01 00:00:00
