CD146 protein in prostate cancer: revisited with two different antibodies.

abstract：:We report a case of multiple hepatic abscesses due to Yersinia enterocolitica in a 58 yr old male. This case is typical of the other 39 cases reported in the literature in that the patient had alcoholism, malnutrition, iron overload and a subsequently diagnosed malignancy. Ultrasound showed multiple hypoechoic areas i...

journal_title：Pathology

authors： Strungs I,Farrell DJ,Matar LD,Dekker L,Franz RJ

更新日期：1995-10-01 00:00:00

abstract：:Certain diagnoses in dermatopathology have significant implications for patient management and on occasion appropriate clinical care may be facilitated by a phone call from the reporting dermatopathologist to the referring doctor. Whether this is appropriate depends on a number of factors. The concept of 'critical dia...

journal_title：Pathology

authors： Korbl JD,Wood BA,Harvey NT

更新日期：2018-04-01 00:00:00

abstract：:HLA-B27 is a risk marker for ankylosing spondylitis and other associated seronegative spondyloarthropathies. We compared three methods of HLA-B*27 typing in a New South Wales (NSW) population: flow cytometry, rs4349859 single nucleotide polymorphism (SNP) detection assay, and allele-specific real-time polymerase chain...

journal_title：Pathology

authors： Jang HS,Proos A,Koe L,Anderson J,Fulton R,Fernando SL

更新日期：2020-02-01 00:00:00

abstract：:The use of purified intrinsic factor in vitamin B12 radioassays has greatly reduced the misdiagnosis of pernicious anaemia in recent years, but anomalies still occur. Observations made on current vitamin B12 radioassays suggest that many methods fail to convert all serum cobalamins to cyanocobalamin and thus are not t...

journal_title：Pathology

authors： Brown RD,Robin H,Kronenberg H

更新日期：1982-01-01 00:00:00

abstract：:Twelve thromboplastins were tested against a secondary reference thromboplastin (human brain CRM BCR No. 147) or a tertiary house standard (human brain thromboplastin) with plasmas from normal healthy individuals and patients on oral anticoagulant therapy. The relationship between the prothrombin ratios of the thrombo...

journal_title：Pathology

authors： Moriarty HT,Lam-Po-Tang PR,Anastas N

更新日期：1990-04-01 00:00:00

abstract：:BAP1 (BRCA1-Associated Protein 1) was initially identified as a protein that binds to BRCA1. BAP1 is a tumour suppressor that is believed to mediate its effects through chromatin modulation, transcriptional regulation, and possibly via the ubiquitin-proteasome system and the DNA damage response pathway. Germline mutat...

journal_title：Pathology

authors： Murali R,Wiesner T,Scolyer RA

更新日期：2013-02-01 00:00:00

abstract：:Distinction between melanocytic naevi and melanoma occasionally poses a diagnostic challenge in ambiguous cases showing overlapping histological features. Melanomas are characterised by the presence of multiple genomic copy number variants (CNVs), while this is not a feature of naevi. We assessed the feasibility and u...

journal_title：Pathology

authors： Mesbah Ardakani N,Thomas C,Robinson C,Mina K,Harvey NT,Amanuel B,Wood BA

更新日期：2017-04-01 00:00:00

abstract：AIMS:To review the benign bone tumours accessioned by the Bone Tumour Registry (BTR) of Western Australia (WA) during the years 1972-1996 and to determine the incidence of the more common types. METHODS:Information was extracted from the Registry database using 58 selected fields. RESULTS:During the 25 year period, 8...

journal_title：Pathology

authors： Blackwell JB,Curnow MN

更新日期：2007-12-01 00:00:00

abstract：:Hypercalcemia is a common biochemical abnormality. It is usually possible to make a presumptive diagnosis of its cause by relatively simple means. In a large majority of cases this involves differentiating between primary hyperparathyroidism and malignancy-associated hypercalcemia. Clinical evaluation and parathyroid ...

journal_title：Pathology

authors： Mason RS

更新日期：1986-04-01 00:00:00

abstract：:Since its first description in the early part of the twentieth century, struma ovarii has elicited considerable interest because of its many unique features; however, at present a number of aspects remain enigmatic. Although the typical presentation is that of a pelvic mass, unusual clinical manifestations such as hyp...

journal_title：Pathology

authors： Roth LM,Talerman A

更新日期：2007-02-01 00:00:00

abstract：:The Hippo pathway is a tumour-suppressive pathway and its inactivation is known to be associated with progression and metastasis of various cancers. LATS1/2 (large tumour suppressor homolog 1 and 2), YAP1 (Yes-associated protein 1), and TEAD4 (TEA domain-containing sequence-specific transcription factors 4) are core c...

journal_title：Pathology

authors： Kim E,Ahn B,Oh H,Lee YJ,Lee JH,Lee Y,Kim CH,Chae YS,Kim JY

更新日期：2019-04-01 00:00:00

abstract：:Seven cases of lower respiratory tract infection due to Corynebacterium pseudodiphtheriticum are described. Lower respiratory tract infections with C. pseudodiphtheriticum in immunocompetent patients are usually associated with pre-existing chronic pulmonary disease, and are sometimes associated with endotracheal intu...

journal_title：Pathology

authors： Freeman JD,Smith HJ,Haines HG,Hellyar AG

更新日期：1994-07-01 00:00:00

abstract：:The values of a number of biochemical variables have been studied before and after a 50-gram load of glucose orally. Reductions which were statistically significant were found for sodium, potassium, urea, total protein, albumin, calcium, phosphorus, urate, bilirubin, alkaline phosphatase, but not for bicarbonate, crea...

journal_title：Pathology

authors： Masarei JR

更新日期：1977-01-01 00:00:00

abstract：:We report a patient with unusual venous and arterial thromboses in association with the common thermolabile methyltetrahydrofolate (MTHFR) variant. The patient responded directly to folate supplementation. To our knowledge, this is the first report describing hyperhomocysteinemia in association with this type of throm...

journal_title：Pathology

authors： Hall TN,Ramakrishnan LL,Leahy MF

更新日期：1999-02-01 00:00:00

abstract：:Various tumour markers have been evaluated in malignant pleural effusions, but not CD66c. This study evaluated the diagnostic ability of CD66c in lung adenocarcinoma-associated malignant pleural effusions (LA-MPEs) and compared it with other known tumour markers. Forty-seven cases of LA-MPE and 52 cases of benign pleu...

journal_title：Pathology

authors： Son SM,Han HS,An JY,Choe KH,Lee KM,Lee KH,Kim SS,Lee YM,Lee HC,Song HG,Lee OJ

更新日期：2015-02-01 00:00:00

abstract：:Epigenetic regulation is emerging as a critical mechanism for pancreatic ductal adenocarcinoma (PDA) development. Histone methylation is an important regulatory mechanism, altering chromatin structure and promoter accessibility and causing aberrant gene expression. NSD1 and SETD2 genes encoding two histone H3K36 methy...

journal_title：Pathology

authors： Ettel M,Zhao L,Schechter S,Shi J

更新日期：2019-06-01 00:00:00

abstract：:The in vitro activity of cefepime was compared to that of a range of other broad-spectrum agents, using a gradient diffusion MIC method, against 995 recent clinical isolates of Enterobacteriaceae, Pseudomonas aeruginosa, other nonfermentative gram-negative bacilli, staphylococci (except oxacillin-resistant Staphylococ...

journal_title：Pathology

authors： Bell JM,Turnidge JD,Cefepime Study Group.

更新日期：2001-02-01 00:00:00

abstract：:The current public health emergency surrounding the COVID-19 pandemic, that is the illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in thousands of cases in Australia since 25 January 2020 when the first case was diagnosed. This emerging virus presents particular hazards to ...

journal_title：Pathology

authors： Kaufer AM,Theis T,Lau KA,Gray JL,Rawlinson WD

更新日期：2020-12-01 00:00:00

abstract：:Lysosome-associated membrane protein-1 (LAMP1) has been suggested to play complicated roles in cancer development and metastasis. The aim of this study was to explore the expression of LAMP1 in laryngeal squamous cell carcinoma (LSCC) and investigate the relationship between LAMP1 expression and clinicopathological ch...

journal_title：Pathology

authors： Lu M,Zhu H,Wang X,Zhang D,Xiong L,Zhu J,Mao Y,Qiang J

更新日期：2016-12-01 00:00:00

abstract：:We describe a 44-year-old female with a known history of a solitary osteochondroma of the scapula followed on X-ray for five years. She then presented with a rapidly growing lump. Imaging studies confirmed the presence of an aggressive looking lesion. Excision was performed and pathology showed a dedifferentiated chon...

journal_title：Pathology

authors： Radhi JM,Loewy J

更新日期：1999-11-01 00:00:00

abstract：:Understanding human genetic variation and how it impacts on gene function is a major focus in genomic-based research. Translation of this knowledge into clinical care is exemplified by pharmacogenetics/pharmacogenomics. The identification of particular gene variants that might influence drug uptake, metabolism, distri...

journal_title：Pathology

authors： Trent RJ,Cheong PL,Chua EW,Kennedy MA

更新日期：2013-06-01 00:00:00

abstract：:Although most carcinomas of the bladder occur de novo, some vesical lesions progress to malignancy over time. These lesions appear morphologically benign, but often harbour genetic changes that signify their malignant potential. Despite their benign appearance, accurate identification is important given that these pat...

journal_title：Pathology

authors： Samaratunga H,Martignoni G,Egevad L,Delahunt B

更新日期：2013-04-01 00:00:00

abstract：:The application of glucose point of care testing (PoCT) in hospitals has been a contentious subject for many years. No information is available regarding the extent to which glucose PoCT is used within the Australian hospital system and whether such testing is fit for its intended purpose. The aim of this study was to...

journal_title：Pathology

authors： Sharp L,Farrance I,Greaves RF

更新日期：2016-01-01 00:00:00

abstract：AIMS:The aim of the study was to evaluate the role of Serpin B3/B4 in advanced idiopathic pulmonary fibrosis (IPF) patients, mainly focusing on epithelial proliferation. METHODS:Lungs from 48 IPF patients (including cases with cancer or high-grade epithelial dysplasia) were studied and compared with other diffuse pare...

journal_title：Pathology

authors： Calabrese F,Lunardi F,Balestro E,Marulli G,Perissinotto E,Loy M,Nannini N,Valente M,Saetta M,Agostini C,Rea F

更新日期：2012-04-01 00:00:00

abstract：:The mitogenic and chemotactic potency of platelet-derived growth factor (PDGF) has linked this polypeptide to the pathogenesis of several disease states including atherosclerosis and neoplasia. We have reviewed the recent literature on aspects relating to the structure, distribution and biology of PDGF and its high-af...

journal_title：Pathology

authors： Khachigian LM,Chesterman CN

更新日期：1992-10-01 00:00:00

abstract：:A histopathological examination was made of 60 stapes obtained during surgery for clinical otosclerosis. The findings, correlated with the clinical history and macroscopic appearances of the stapes, led to the following observations. The histological extent of the focus of otosclerosis agrees well with the macroscopic...

journal_title：Pathology

authors： Iyer PV,Gristwood RE

更新日期：1984-01-01 00:00:00

abstract：AIMS:In hereditary colorectal cancer (CRC) disorders such as familial adenomatous polyposis and hereditary non-polyposis colon cancer, the identification of germline mutations greatly assists in the clinical management of families. In addition, study of somatic mutations in the cancers themselves (both hereditary and s...

journal_title：Pathology

authors： Young J,Barker M,Fraser L,Walsh MD,Spring K,Biden KG,Hopper JL,Leggett BA,Jass JR

更新日期：2002-12-01 00:00:00

abstract：:A method for the preparation of human renal biopsy specimens for scanning electron microscopy (SEM) is described. This involves glomerular isolation by fine needle dissection and the simultaneous processing of 10 or more specimens in a specially designed tissue cassette. The method is simple and reliable with minimal ...

journal_title：Pathology

authors： Ng W,So KF,So PC,Ngai HK

更新日期：1982-07-01 00:00:00

abstract：:In order to determine whether routine culturing for Clostridium difficile was warranted or whether culturing a selected group of patients was adequate, we conducted a prospective trial of culturing all stool specimens for C. difficile. A total of 408 specimens from 297 patients was studied. Two hundred and eighteen st...

journal_title：Pathology

authors： Bowman RA,Riley TV

更新日期：1984-07-01 00:00:00

abstract：AIMS:In our previous studies, comparative proteomics demonstrated that lactate dehydrogenase B subunit (LDH-B) is down-regulated in high grade compared to non-high grade urinary bladder urothelial carcinoma (UBUC). However, this finding has not been validated by clinical cohort investigation. Therefore, in the present ...

journal_title：Pathology

authors： Liao AC,Li CF,Shen KH,Chien LH,Huang HY,Wu TF

更新日期：2011-12-01 00:00:00