Abstract:
:A method for the preparation of human renal biopsy specimens for scanning electron microscopy (SEM) is described. This involves glomerular isolation by fine needle dissection and the simultaneous processing of 10 or more specimens in a specially designed tissue cassette. The method is simple and reliable with minimal glomerular loss during processing. Processed glomeruli appear intact under the SEM. They have clean surfaces with minimal extraneous deposits. Surface topography of the glomerulus is clearly seen and changes of the podocytes in glomerular diseases can be readily studied.
journal_name
Pathologyjournal_title
Pathologyauthors
Ng W,So KF,So PC,Ngai HKdoi
10.3109/00313028209061381subject
Has Abstractpub_date
1982-07-01 00:00:00pages
299-302issue
3eissn
0031-3025issn
1465-3931journal_volume
14pub_type
杂志文章相关文献
PATHOLOGY文献大全abstract::Rapid rescreening was established in our laboratory in 1995, following the publication of several studies indicating improved sensitivity for the detection of abnormalities in cervical smears. During the study period, 285,841 negative smears (representing 89.09% of the total workload) were rapidly rescreened. A total ...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/003130299104765
更新日期:1999-11-01 00:00:00
abstract::Solitary fibrous tumour (SFT) is well-described in the urinary tract, but malignant examples are rare. We studied our experience with high grade malignant SFT of the prostate to address the degree of histological and immunophenotypical overlap with sarcomatoid carcinoma and prostatic stromal sarcoma. Four cases were i...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2020.06.004
更新日期:2020-10-01 00:00:00
abstract:AIMS:Hep Par 1 has been described as a specific marker of hepatocellular differentiation and its immunohistochemical use has been suggested as a helpful tool for hepatocellular carcinoma (HCC) diagnosis. Most metastatic liver tumours come from the gastrointestinal tract and usually can be distinguished from HCC only th...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/0031302021000009333
更新日期:2002-10-01 00:00:00
abstract:AIMS:Pancreatic endocrine tumours (PET) containing ductules are an uncommon histological variant. Considerable conjecture surrounds the origin and histogenesis of the ductules. Opinions range from the ductules being an inherent part of the tumour, to others who feel they are merely entrapped. A study of 21 cases of thi...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/00313020500444633
更新日期:2006-02-01 00:00:00
abstract::An improved one-stage method for accurate assays of factor VIII combines highly reproducible end points with elimination of temporal drift and of subjective factors involved in graphic analysis. Activated deficient plasma substrate (ADPS) is used as a single reagent for parallel tests. The assays can be performed manu...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313027909061940
更新日期:1979-04-01 00:00:00
abstract::Papillary proliferations of the endometrium (PPEs) are uncommon lesions that are often associated with endometrial polyps. PPEs occasionally precede or co-exist with atypical endometrial hyperplasia or adenocarcinoma, but their pathogenesis and relationship to endometrial neoplasia is uncertain. In the present study 1...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2017.10.013
更新日期:2018-04-01 00:00:00
abstract::We report a rare case of bilateral primary seminal vesicle carcinoma in a 73 yr old Australian man. To our knowledge this case report is the 48th histologically confirmed case of primary seminal vesicle neoplasia and only the fourth reported case of primary bilateral seminal vesicle carcinoma. Macroscopically the tumo...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/00313029600169883
更新日期:1996-05-01 00:00:00
abstract::Ebolaviruses, and the other viral causes of haemorrhagic fevers (VHF) have always posed special problems for diagnostic laboratories. These arise from the rarity of human infections, minimal documented experience with test delivery and interpretation, the paucity of established commercial or in-house assays, the lack ...
journal_title:Pathology
pub_type: 杂志文章,评审
doi:10.1097/PAT.0000000000000292
更新日期:2015-08-01 00:00:00
abstract::Review of problematic melanocytic consultation cases has enabled identification of the most common variants of benign melanocytic proliferations which can be confused with melanoma. Apart from Spitz naevus, the most common in this group of lesions are pigmented spindle cell naevus and atypical dermal nodule. Potential...
journal_title:Pathology
pub_type: 杂志文章,评审
doi:10.1080/00313020412331283842
更新日期:2004-10-01 00:00:00
abstract:AIMS:There are many variants of papillary carcinoma, and some of these variants have been reported to show biological behaviours differing from that of conventional papillary carcinoma. In this study, we present our experience regarding the prevalence and prognoses of these variants of papillary carcinoma. METHODS:H&E...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/00313020802320630
更新日期:2008-10-01 00:00:00
abstract::The distinction between partial hydatidiform mole (PHM) and trisomy gestation is not always straightforward histologically and it is unclear which morphological features, alone or in combination, provide the greatest diagnostic accuracy. We performed a comparative review of 89 products of conception (POC) specimens in...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2016.06.006
更新日期:2016-10-01 00:00:00
abstract::Antibodies that bind phospholipid (anti-phospholipid antibodies [APA]) are a focus of major interest to both clinical and laboratory personnel across a variety of disciplines because of the assortment of disorders with which they are reportedly associated. A solid phase assay using cardiolipin as the test phospholipid...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/003130299105331
更新日期:1999-05-01 00:00:00
abstract::We evaluated an immunoradiometric assay for serum TSH (IRMA-TSH) and compared it with established indices of thyroid function in 208 patients with either frank thyroid disease, conditions of abnormal thyroxine protein binding, or conditions which are known to produce discordant thyroid results, viz. pregnancy or estro...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313028709066554
更新日期:1987-07-01 00:00:00
abstract::The use of purified intrinsic factor in vitamin B12 radioassays has greatly reduced the misdiagnosis of pernicious anaemia in recent years, but anomalies still occur. Observations made on current vitamin B12 radioassays suggest that many methods fail to convert all serum cobalamins to cyanocobalamin and thus are not t...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313028209069040
更新日期:1982-01-01 00:00:00
abstract:AIMS:To investigate KAI1 and survivin expression in infiltrating ductal carcinomas, and to evaluate the relationship between clinicopathological factors and KAI1 and survivin expression levels in breast cancers. METHODS AND RESULTS:KAI and survivin expression levels were measured in 62 patients, using immunohistochemi...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/00313020500058144
更新日期:2005-04-01 00:00:00
abstract::Endomyocardial biopsy (EMB) is a highly-specialised procedure that is associated with some controversy as to its diagnostic role due to its inconsistency in diagnosing a wide variety of cardiac diseases. Given the advances and sophistication in echocardiography and cardiac magnetic resonance imaging (MRI), the vast ma...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2017.08.004
更新日期:2017-12-01 00:00:00
abstract::Tissue from the epiphyseal plate of a patient with Morquio type A syndrome (mucopolysaccharidosis type IVA) was studied by undecalcified histological and electron microscopical techniques. Cartilage cells in the plate were vacuolated to a variable degree. The orderly proliferating structure of the epiphyseal plate was...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313028609059462
更新日期:1986-04-01 00:00:00
abstract::Tumour infiltrating lymphocytes in primary melanoma have been found to correlate with patient outcomes. A subpopulation of tumour infiltrating lymphocytes expresses the transcription factor forkhead box protein 3 (FOXP3). These are known as FOXP3+ T-regulatory cells (Tregs) and are thought to play an immune suppressiv...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1097/PAT.0000000000000314
更新日期:2015-10-01 00:00:00
abstract::We describe a case of ductal carcinoma in situ (DCIS) occurring in a fibroadenoma diagnosed by fine needle aspiration (FNA) cytology. The cytological features comprised a small population of pleomorphic cells admixed with a dominant population of bland epithelial cells showing features consistent with those of a fibro...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/00313029800169736
更新日期:1998-11-01 00:00:00
abstract::In situ stages of malignancy have been characterised in various neoplasms. Mesothelioma in situ (MIS) has been a controversial diagnosis, lacking clear diagnostic criteria and understanding as to whether it is truly a premalignant lesion in the progression of malignant mesothelioma (MM). Originally understood as a con...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2020.06.010
更新日期:2020-10-01 00:00:00
abstract::BAP1 (BRCA1-Associated Protein 1) was initially identified as a protein that binds to BRCA1. BAP1 is a tumour suppressor that is believed to mediate its effects through chromatin modulation, transcriptional regulation, and possibly via the ubiquitin-proteasome system and the DNA damage response pathway. Germline mutat...
journal_title:Pathology
pub_type: 杂志文章,评审
doi:10.1097/PAT.0b013e32835d0efb
更新日期:2013-02-01 00:00:00
abstract::The field of systemic cancer therapy for metastatic disease has entered an exciting era with the advent of novel immunomodulatory strategies targeting immune checkpoints. At the heart of these promising efforts are the tumour-infiltrating lymphocytes (TILs). As the reports demonstrating efficacy of modulating TIL effe...
journal_title:Pathology
pub_type: 杂志文章,评审
doi:10.1016/j.pathol.2015.12.006
更新日期:2016-02-01 00:00:00
abstract::A study of 103 fetal adrenals obtained from stillborn fetuses and those dying in the neonatal period was performed to assess the significance of definitive cortex cystic change, compact cell change and lipid patterns, and their relationship to other pathological processes. The findings confirm that these changes are m...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313028409068543
更新日期:1984-07-01 00:00:00
abstract::A case is described of a mediastinal soft tissue sarcoma, in a 76-year-old man, characterized microscopically by the intimate combined features of liposarcoma and leiomyosarcoma. The lipomatous component consisted of well differentiated liposarcoma with myxoid areas. The smooth muscle component was characterized by fa...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/00313029700169475
更新日期:1997-11-01 00:00:00
abstract::Post-transplant lymphoproliferative disorders (PTLD) are a consequence of the immunosuppressive therapy following organ transplant. We describe a patient who developed PTLD seven years after liver transplant and while receiving cyclosporine and prednisone. Magnetic resonance imaging demonstrated a paraspinal mass exte...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/00313029800169636
更新日期:1998-11-01 00:00:00
abstract::Perhexiline maleate is a potent anti-anginal drug which may cause alcoholic-type hepatitis and cirrhosis. We report a case of a patient who developed cirrhosis on a relatively low dose within 16 mth. ...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313028309084714
更新日期:1983-04-01 00:00:00
abstract:AIMS:To assess the production of a liver-specific protein, albumin, and of a master transcriptional factor, hepatocyte nuclear factor (HNF)-4alpha, in hepatoid adenocarcinoma tissue. METHODS:Standard and quantitative RT-PCR, using five cases of hepatoid and three cases of non-hepatoid gastric adenocarcinoma. RESULTS:...
journal_title:Pathology
pub_type: 杂志文章
doi:
更新日期:2003-02-01 00:00:00
abstract:AIMS:To review the benign bone tumours accessioned by the Bone Tumour Registry (BTR) of Western Australia (WA) during the years 1972-1996 and to determine the incidence of the more common types. METHODS:Information was extracted from the Registry database using 58 selected fields. RESULTS:During the 25 year period, 8...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/00313020701684334
更新日期:2007-12-01 00:00:00
abstract::The cell surface markers of 75 cases of non-Hodgkin's lymphoma were studied on cryostat sections using a panel of monoclonal antibodies. Forty-nine cases (65.3%) were found to express a B-cell phenotype, 23 cases (30.7%) a T-cell phenotype, 1 case (1.3%) a histiocytic phenotype and 2 cases (2.7%) no demonstrable surfa...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313028609087562
更新日期:1986-10-01 00:00:00
abstract::Lymph node metastasis (LNM) is an important factor for predicting prognosis and selecting appropriate treatment in early gastric cancers (EGCs). We investigated the histopathological and microenvironmental predictors of LNM in EGCs. We retrieved 43 cases of EGC without LNM and 59 cases with LNM. Clinicopathological va...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2017.06.003
更新日期:2017-10-01 00:00:00