Abstract:
:The use of 14C as tracer to measure lactate turnover and oxidation and its role in gluconeogenesis are discussed. Lactate is formed as well as utilized in many cells, and most of it in the body is present within cells so that interpretation of 14C data from labelled lactate is more complex and more difficult than that of compounds present largely extracellularly, such as glucose. Apparent uptake of [14C]lactate may occur in the absence of net lactate utilization, and 14CO2 production does not provide a measure of true lactate oxidation. In vivo sites of tracer administration and sampling of blood are of critical significance for evaluation of lactate turnover, lactate space, its incorporation into glucose, and oxidation.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Katz Jdoi
10.1249/00005768-198606000-00018subject
Has Abstractpub_date
1986-06-01 00:00:00pages
353-9issue
3eissn
0195-9131issn
1530-0315journal_volume
18pub_type
杂志文章abstract::Anthropometric and demographic characteristics are important determinants of exercise performance in healthy subjects, but their influence has not yet been studied in severe chronic heart failure, although peak oxygen uptake is frequently assessed in such patients for prognostic purposes. The aim of the present analys...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199706000-00002
更新日期:1997-06-01 00:00:00
abstract::Myocardial crypts are extensions of blood signal penetrating the compact myocardium and are considered in literature as either a distinctive cardiac magnetic resonance (CMR) imaging marker for hypertrophic cardiomyopathy or as benign congenital malformations. What if CMR reveals a myocardial crypt in the presence of a...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000406
更新日期:2015-02-01 00:00:00
abstract::The physiological mechanism of exercise-induced hyperfibrinolysis is not fully understood. It has been reported that exercise increases plasma arginine vasopressin (PAVP) and that PAVP infusion enhances blood fibrinolytic activity (FA). To characterize the fibrinolytic role of PAVP during exercise, PAVP and FA were ex...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1990-08-01 00:00:00
abstract:INTRODUCTION:Low lean mass (LM) is a risk factor for chronic disease, a major cause of disability and diminished quality of life, and is a heritable trait. However, relatively few specific genetic factors have been identified as potentially influencing this trait. METHODS:In this study, we selected 1493 single-nucleot...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000889
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:This study examined the relationship between age and gender with physical activity (PA) and how meeting of PA guidelines (PAGL) is related to socioeconomic status (SES) and sedentary behaviors (SB). METHODS:Data were collected from 11-, 13-, and 15-yr-old students in 32 countries participating in the Health Be...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181917722
更新日期:2009-04-01 00:00:00
abstract:PURPOSE:Previous studies have suggested that extreme endurance exercise may induce cardiac microdamage that could lead to subsequent myocardial fibrosis. Soluble suppression of tumorigenicity 2 (sST2) is a cardiac biomarker for assessment of myocardial fibrosis, inflammation, and strain. We evaluated baseline and exerc...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001806
更新日期:2019-03-01 00:00:00
abstract:INTRODUCTION:Exogenous ketones potentially provide an alternative, energetically advantageous fuel to power exercising skeletal muscle. However, there is limited evidence regarding their relative contribution to energy expenditure during exercise. Furthermore, the effect of blood ketone concentration and exercise inten...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002502
更新日期:2020-08-28 00:00:00
abstract:UNLABELLED:Cell-derived procoagulant microparticles (MP) might be able to contribute to exercise-induced changes in blood hemostasis. PURPOSES:This study aimed to examine (i) the concentration and procoagulant activity of cell-derived MP after a moderate endurance exercise and (ii) the differences in the release, clea...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/MSS.0b013e3182068645
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:The best sprint performances are usually reached between the ages of 20 and 30 yr; however, even in well-trained individuals, performance continues to decrease with age. Although this inevitable decrease in performance has been related to reductions in muscular force, velocity, and power capabilities, these mea...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001039
更新日期:2016-12-01 00:00:00
abstract::The close balance between the O2 requirement to perform exercise and the O2 supply was analyzed. A non-uniform capillary PO2 can result in anaerobic metabolism in some muscle fibers despite an apparently adequate mean capillary PO2. The pattern of lactate increase for constant work rates and incremental exercise is de...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-198606000-00017
更新日期:1986-06-01 00:00:00
abstract::A decrease in hepatic lactate dehydrogenase (LDH) activity following endurance training has been a consistent observation. In the present study, we sought to determine whether the training-induced decrease in hepatic LDH activity (pyruvate = substrate) was associated with a shift in the isoenzyme profile and/or altera...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract::Two swims (1993 and 1994) are described which led to post-swim orthostatic intolerance and one episode of syncope in a 50/51-yr-old well-trained and experienced marathon swimmer. The swims of 33 km and 38 km took 12 h 30 s and 17 h 35 min, respectively. Water temperature in each swim was above 23 degrees C and rectal ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1995-09-01 00:00:00
abstract::The objective of this study was to design and validate a working tool for the objective evaluation of daily energy expenditure (DEE) by means of a simple, noninvasive method: the QAPSE (Saint-Etienne Physical Activity Questionnaire), a questionnaire about physical activity (PA) over a period of 7 d (168 h). This eight...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract:PURPOSE:Cardiac troponin T (cTnT) is a highly specific marker of myocardial damage and used clinically in the diagnosis of acute myocardial infarction (AMI). Release of cTnT has been demonstrated in several small studies after endurance exercise. The purpose of this study was to explore, using a meta-analytic approach,...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,meta分析
doi:10.1249/mss.0b013e318153ff78
更新日期:2007-12-01 00:00:00
abstract::Hydrostatic weighing (HW) was performed at residual volume (RV) and total lung capacity without head submersion (TLCNS). Ninety-five males (25.6 +/- 4.9 yr) and 87 females (22.6 +/- 5.2 yr) were studied at two laboratory sites using identical protocols. Twenty males and 20 females were separated from the original grou...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1249/00005768-198802000-00010
更新日期:1988-02-01 00:00:00
abstract::The relationship between VO2 and velocity of running (running economy) has been rather casually dealt with until very recently, and there still remains considerable disagreement as to the importance of this variable. Various factors which have been shown, or appear, to affect running economy include environment (tempe...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1985-06-01 00:00:00
abstract:BACKGROUND:The Sedentary Sphere is a method for the analysis, identification, and visual presentation of sedentary behaviors from a wrist-worn triaxial accelerometer. PURPOSE:This study aimed to introduce the concept of the Sedentary Sphere and to determine the accuracy of posture classification from wrist acceleromet...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000224
更新日期:2014-06-01 00:00:00
abstract::Muscle fatigue has been studied with a variety approaches, tools and technologies. The foci of these studies have ranged tremendously, from molecules to the entire organism. Single cell and animal models have been used to gain mechanistic insight into the fatigue process. The theme of this review is the concept that t...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1249/MSS.0000000000001052
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:The extent to which the diaphragm is targeted during a bout of inspiratory muscle training (IMT) is unknown. The purpose of this study was to characterize the relative activation patterns of the diaphragm and extradiaphragmatic inspiratory muscles during a bout of IMT and to determine whether diaphragmatic recr...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000881
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:Splanchnic hypoperfusion is a physiological phenomenon during strenuous exercise. It has been associated with gastrointestinal symptoms and intestinal injury and may hamper athletic performance. We hypothesized that L-citrulline supplementation improves splanchnic perfusion and decreases intestinal injury by en...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000000332
更新日期:2014-11-01 00:00:00
abstract::Twelve 9- to 12-year-old children (6 boys, 6 girls) performed four exercise-in-heat (35 degrees C, 45% RH) trials which differed in the composition of the fluids they drank. In each trial, subjects cycled for one 20-min and two 15-min bouts at 50% peak VO2 with 10-min rest periods in between. In a fourth bout, they cy...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-06-01 00:00:00
abstract:PURPOSE:Endurance training improves skeletal muscular function including energy metabolism and structure. Sex steroid hormones partly contribute to the exercise-induced muscular adaptations. Recently, we demonstrated that skeletal muscle contains steroidogenic converting enzymes to synthesize sex steroid hormones and a...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31821e9d74
更新日期:2011-11-01 00:00:00
abstract:PURPOSE:To better understand the mechanical behavior of healing skeletal muscle; specifically the tissue's response after acute eccentric stretch injury. METHODS:Rabbit tibialis anterior (TA) muscle tendon units were subjected to an in vivo single stretch (eccentric) injury and mechanically evaluated (constant rate el...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000084423.39529.C5
更新日期:2003-09-01 00:00:00
abstract:PURPOSE:Existing studies have failed to provide evidence of a positive effect on exercise performance by wearing compression short tights covering only both thighs. This could be due to an inadequate pressure intensity that otherwise has a significant effect if applied on the crucial point in the thigh. This study aime...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000330
更新日期:2014-11-01 00:00:00
abstract:INTRODUCTION:At the present there are limited tools available to measure muscle function in young children. Ground reaction force plates measure lower-body function and postural control in older children and adults. The purpose of this study was threefold: 1) develop normative data for evaluating global muscle developm...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000340
更新日期:2014-11-01 00:00:00
abstract:PURPOSE:To assess physical activity, and its associations with health, clinical, and biochemical factors, in patients with stages 2-4 of chronic kidney disease (CKD). METHODS:Cross-sectional data were collected from 120 patients with CKD enrolled in the Lipid lowering and Onset of Renal Disease (LORD) trial. Patients ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181940aef
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:This study investigated the changes in running mechanics and spring-mass behavior over a 24-h treadmill run (24TR). METHODS:Kinematics, kinetics, and spring-mass characteristics of the running step were assessed in 10 experienced ultralong-distance runners before, every 2 h, and after a 24TR using an instrumen...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181fec518
更新日期:2011-05-01 00:00:00
abstract::Bicycling is a complex sport in which an athlete's energy cost is related to two principal forces: air resistance when traveling on flat terrain, and gravity when traveling uphill. Both wind tunnel data and physiological measurements suggest that air resistance scales as body mass to about the 1/3 power. Thus, large c...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract::Facial cooling (FC) elicits a marked bradycardia at rest that appears to be reduced during exercise. This study was done to delineate the effects of exercise mediated central command from those of muscle afferent feedback and sympathetic stimulation on the attenuation of the bradycardic effect of FC during the onset o...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199703000-00006
更新日期:1997-03-01 00:00:00
abstract:PURPOSE:Above a given exercise intensity, rapid muscle fatigue will occur. We explored the possibility of assessing torque threshold for peripheral fatigue during single-legged repetitive isometric knee extensor exercise. We hypothesized this fatigue threshold to be related to the general aerobic fitness level and the ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318249d701
更新日期:2012-07-01 00:00:00