Abstract:
:Experience with systemic or selective local administration of thrombolytic agents in pediatric ischemic stroke is limited to sporadic case reports, since patients of age less than 18 years were systematically excluded from randomised controlled trials. We report a case of childhood IS attributable to the terminal internal carotid artery occlusion that was treated successfully with mechanical thrombectomy which followed unsuccessful attempts to recanalize the artery with intravenous and intra-arterial thrombolytics. Combined systemic and intra-arterial thrombolysis followed by mechanical thrombectomy can be feasible and may be considered as means of achieving reperfusion in pediatric ischemic stroke patients with persisting arterial occlusion.
journal_name
J Neurol Scijournal_title
Journal of the neurological sciencesauthors
Tsivgoulis G,Horton JA,Ness JM,Patterson D,Brethour M,Abanses JC,Alexandrov AVdoi
10.1016/j.jns.2008.07.018subject
Has Abstractpub_date
2008-12-15 00:00:00pages
151-3issue
1-2eissn
0022-510Xissn
1878-5883pii
S0022-510X(08)00363-8journal_volume
275pub_type
杂志文章abstract::In addition to neuritic changes and amyloid deposits, neuronal and glial cell apoptosis is an important pathological feature of Alzheimer's disease (AD). Several factors have been postulated as causes or triggers of cellular apoptotic change. This study focused on a quantifiable relationship between phosphorylation si...
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pub_type: 杂志文章,评审
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