Dopaminergic agonist Ro 8-4650 in Parkinson's disease. II. Patients not treated with dopa.

abstract：:Anti-muscle-specific receptor tyrosine kinase (MuSK) antibody-positive myasthenia gravis (MG) patients show various responses to conventional immunosuppressive treatment and some patients are resistant to these therapies. We report a 50-year-old Japanese man with anti-MuSK antibody-positive MG, who showed no or poor r...

journal_title：Acta neurologica Scandinavica

authors： Shibata-Hamaguchi A,Samuraki M,Furui E,Iwasa K,Yoshikawa H,Hayashi S,Yamada M

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Delayed-release dimethyl fumarate (DMF) treatment can be associated with reduced lymphocyte and leucocyte counts, which might persist after DMF discontinuation. CASE PRESENTATION:We report the case of a patient with severe disease reactivation despite prolonged lymphopenia after DMF discontinuation. We desc...

journal_title：Acta neurologica Scandinavica

authors： Zecca C,Antozzi CG,Torri Clerici V,Ferrazzini M,Mantegazza RE,Rossi S,Gobbi C

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:To examine differences in cerebrovascular reactivity between multi-infarct and Alzheimer types of dementia. PATIENTS AND METHODS:Using transcranial Doppler, measurements of flow velocity in the middle cerebral arteries during apnea, thumb-to-finger opposition and verbal and design discrimination tasks were ...

journal_title：Acta neurologica Scandinavica

authors： Matteis M,Silvestrini M,Troisi E,Bragoni M,Vernieri F,Caltagirone C

更新日期：1998-06-01 00:00:00

abstract：:Although intravenous (i.v.) heparin is widely used as the first line treatment for cerebral venous and sinus thrombosis (CVST), the most appropriate therapy for this disease is still controversial. We report 2 cases of CVST who were successfully treated by means of loco-regional thrombolysis with urokinase. In the fir...

journal_title：Acta neurologica Scandinavica

authors： Buccino G,Scoditti U,Pini M,Menozzi R,Piazza P,Zuccoli P,Mancia D

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:We describe 2 patients with epilepsy as an early manifestation of late onset metachromatic leukodystrophy (MLD). METHODS AND RESULTS:The first patient presented with epileptic seizures at the age of 34 years while neurological and cognitive abnormalities appeared later. MRI findings were compatible with leu...

journal_title：Acta neurologica Scandinavica

authors： Bostantjopoulou S,Katsarou Z,Michelakaki H,Kazis A

更新日期：2000-09-01 00:00:00

abstract：:Beta-2-microglobulin (beta 2m) levels were studied in the cerebrospinal fluid (CSF) and plasma of 52 patients with clinically definite multiple sclerosis (MS) and of 14 with aseptic meningo-encephalitis (AM). Reference values for beta 2m were defined in 72 subjects of different age groups with tension headache (TH). P...

journal_title：Acta neurologica Scandinavica

authors： Us O,Lolli F,Baig S,Link H

更新日期：1989-12-01 00:00:00

abstract：:While chewing and grinding movements have been observed in amphetamine addicts, recognition and management of this problem have rarely been highlighted. Botulinum toxin (BTX) has previously been demonstrated to be effective for bruxism associated with movement disorders, such as cranial-cervical dystonia. However, the...

journal_title：Acta neurologica Scandinavica

authors： See SJ,Tan EK

更新日期：2003-02-01 00:00:00

abstract：:Epileptic seizures are refractory to treatment in approximately one-third of patients despite the recent introduction of many newer antiepileptic drugs (AEDs). Development of novel AEDs therefore remains a high priority. Perampanel is a first-in-class non-competitive selective AMPA receptor antagonist with a unique me...

journal_title：Acta neurologica Scandinavica

authors： Tsai JJ,Wu T,Leung H,Desudchit T,Tiamkao S,Lim KS,Dash A

更新日期：2018-04-01 00:00:00

abstract：:The effect of the alpha-adrenergic blocking agent thymoxamine by intravenous administration was studied in 25 patients with spastic paraplegia and uninhibited neurogenic bladder. By cystometry a shift to the right of the first desire to void, the threshold of the first uninhibited contraction and a reduction of the pr...

journal_title：Acta neurologica Scandinavica

authors： Pedersen E,Tørring J,Klemar B

更新日期：1980-02-01 00:00:00

abstract：:We investigated the types of syndrome, location, size and presumed causes of 72 patients with acute capsular lacunar infarction. Clinical syndromes were classified into pure motor hemiparesis (PM), sensorimotor stroke (SM) and ataxic hemiparesis (AH). Lesion sizes of AH were significantly smaller than those of PM (p <...

journal_title：Acta neurologica Scandinavica

authors： Tei H,Uchiyama S,Maruyama S

更新日期：1993-10-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) deletions have been noted in small quantities in a handful of atypical cases of myotonic dystrophy and there are clinical and pathological parallels between this autosomal dominant disease and certain mitochondrial myopathies where such deletions are well recognised. We studied 20 individuals...

journal_title：Acta neurologica Scandinavica

authors： Thyagarajan D,Byrne E,Noer S,Lertrit P,Utthanophol P,Kapsa R,Marzuki S

更新日期：1993-01-01 00:00:00

abstract：:Demented patients with Alzheimer's disease (AD) (n = 67), multi-infarct dementia (MID) (n = 77) and probable vascular dementia (PVD) (n = 45) were studied with electroencephalography (EEG). All patients underwent a routine EEG examination and quantitative EEG was recorded from 14 patients with AD, 20 with MID, and 12 ...

journal_title：Acta neurologica Scandinavica

authors： Erkinjuntti T,Larsen T,Sulkava R,Ketonen L,Laaksonen R,Palo J

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVES:To study the prevalence of antibodies of IgA class against tissue transglutaminase (tTG), endomysium (EMA) and gliadin (AGA) in patients with chronic idiopathic axonal polyneuropathy (CIAP) and to characterize the patients clinically and neurophysiologically. METHODS:Of 182 patients, 126 patients agreed to ...

journal_title：Acta neurologica Scandinavica

authors： Vrethem M,Lindh J,Tondel M,Persson B,Dahle C

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:To estimate the need for and the costs of carotid Doppler and carotid endarterectomy after stroke or TIA in non-selected hospitalized patients. MATERIAL AND METHODS:During 25 months hospitalized patients with stroke or TIA, in whom carotid endarterectomy could be relevant, were examined with carotid Doppler...

journal_title：Acta neurologica Scandinavica

authors： Jespersen HF,Jørgensen HS,Nakayama H,Reith J,Olsen TS

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Cerebrospinal fluid (CSF) pressure-volume compensation may change over time as part of normal ageing, where the resistance to CSF outflow increases and the formation of CSF decreases with age. Is CSF compensation dependent on duration of symptoms in idiopathic normal pressure hydrocephalus (iNPH)? METHODS:We...

journal_title：Acta neurologica Scandinavica

authors： Czosnyka Z,Owler B,Keong N,Santarius T,Baledent O,Pickard JD,Czosnyka M

更新日期：2011-06-01 00:00:00

abstract：:The etiological characteristics of cerebrovascular disease (CVD) before the age of 55 are reviewed in 399 patients admitted to the Department of Neurology, Karolinska Hospital, Stockholm, from 1973-77. The material was well-defined with regard to subtypes of stroke as well as to the diseased population. The control ma...

journal_title：Acta neurologica Scandinavica

authors： Mettinger KL,Söderström CE,Neiman J

更新日期：1984-12-01 00:00:00

abstract：:In 5 patients with definite or highly probable MS, unusually large hypodense plaques are seen by computerized tomography (CT scan). The active plaques all show enhancement after i.v. contrast medium injection, suggestive of blood-brain-barrier-damage, and differ from the well-known CT findings in chronic MS patients, ...

journal_title：Acta neurologica Scandinavica

authors： Lidegaard O,Gyldensted C,Juhler M,Zeeberg I

更新日期：1983-08-01 00:00:00

abstract：:The occurrence of cerebral infarction in patients with transient global amnesia (n = 43) was evaluated by CT scan and compared to that of patients with transient ischemic attacks (TIA) (n = 58) and with no neurological disease (n = 52). Significant differences were demonstrated between TGA and TIA patients in relation...

journal_title：Acta neurologica Scandinavica

authors： Matias-Guiu J,Colomer R,Segura A,Codina A

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVES:To measure gait and postural stability by objective methods in spastic MS patients and to evaluate the effect of baclofen on gait and postural stability. PATIENTS AND METHODS:Fourteen spastic MS patients were examined in a placebo controlled double-blind, cross-over trial of oral baclofen treatment. The gai...

journal_title：Acta neurologica Scandinavica

authors： Orsnes GB,Sørensen PS,Larsen TK,Ravnborg M

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVES:There is paucity of information about the association of seizure severity and quality of life in people with epilepsy (PWE) in sub-Saharan Africa. We evaluated the relationship of seizure severity to health-related quality of life of patients with epilepsy being followed up in an outpatient neurology clinic ...

journal_title：Acta neurologica Scandinavica

authors： Adebayo PB,Akinyemi RO,Ogun SA,Ogunniyi A

更新日期：2014-02-01 00:00:00

abstract：:The spontaneous occurrence of blepharospasm and dystonic movements in face muscles, particularly those of the perioral and mandibular regions, has been named as Meige's disease which was first described by Henry Meige in 1910. We report the case of a woman with Meige's syndrome whose symptoms improved with the use of ...

journal_title：Acta neurologica Scandinavica

authors： Yardimci N,Karatas M,Kilinc M,Benli S

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:There is a paucity of regional cerebral blood flow studies in Japanese encephalitis (JE). In this communication we report clinical, radiological and single photon emission computed tomography findings in subacute and chronic JE patients. MATERIAL AND METHODS:Eight JE patients whose ages ranged between 10 and...

journal_title：Acta neurologica Scandinavica

authors： Kalita J,Das BK,Misra UK

更新日期：1999-04-01 00:00:00

abstract：INTRODUCTION:Cognitive impairment is a common and disabling consequence of stroke. Its prevalence, the best way to screen for it in the acute setting, and its relation with premorbid status have not been thoroughly clarified. MATERIALS AND METHODS:Ischemic and hemorrhagic stroke patients admitted to our stroke unit un...

journal_title：Acta neurologica Scandinavica

authors： Cova I,Mele F,Zerini F,Maggiore L,Cucumo V,Brambilla M,Rosa S,Bertora P,Salvadori E,Pomati S,Pantoni L

更新日期：2020-10-01 00:00:00

abstract：:The results of follow-up of 76 children with progressive ataxia first reported in 1988 are described with special reference to type of potential underlying metabolic diseases. In 70% of cases the clinical follow-up did not lead to reconsideration of diagnoses. Six of 23 biochemically and morphologically re-examined ch...

journal_title：Acta neurologica Scandinavica

authors： Ylitalo V,Hagberg BA

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:Although patients >80 years were excluded in RCTs for tPA treatment of acute ischemic stroke (AIS), many centers treat old patients. We wanted to examine whether age ≥80 years is an independent predictor of outcome after tPA. MATERIALS:We included 77 consecutive patients ≥80 years and 83 patients <80 years t...

journal_title：Acta neurologica Scandinavica

authors： Henriksen EH,Ljøstad U,Tveiten A,Naess H,Thomassen L,Mygland A

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine whether reactivation of Epstein-Barr (EBV) or activation of the anti-EBV immune response correlates with MS disease activity on MR imaging. METHODS:Subjects with early, active relapsing-remitting MS were studied for 16 weeks with blood and saliva samples collected...

journal_title：Acta neurologica Scandinavica

authors： Latham LB,Lee MJ,Lincoln JA,Ji N,Forsthuber TG,Lindsey JW

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the epidemiological and clinical features of motor neuron disease (MND) in a region (835,000 inhabitants) of south-western Greece. PATIENTS AND METHODS:The medical records of all patients diagnosed with adult-onset MND at the Department of Neurology of the University Hospital of Patras from 1990 ...

journal_title：Acta neurologica Scandinavica

authors： Argyriou AA,Polychronopoulos P,Papapetropoulos S,Ellul J,Andriopoulos I,Katsoulas G,Salakou S,Chroni E

更新日期：2005-02-01 00:00:00

abstract：:Eleven patients with presenile Alzheimer type dementia (ATD) were treated with N-terminal ACTH fragments for 14 days. No change in cognitive functions was observed during the treatment. A significant increase in CSF beta-endorphin (beta-EP) levels was found, while ACTH and beta-lipoprotein remain unaffected. The possi...

journal_title：Acta neurologica Scandinavica

authors： Nappi G,Facchinetti F,Martignoni E,Petraglia F,Sinforiani E,Bono G,Genazzani AR

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVE:In a previous study, we found that nine of the 47 siblings to multiple sclerosis (MS) patients with a normal neurologic examination carry an intrathecal oligoclonal immunopathy with limited specificity, a condition we termed MS immunopathic trait. Here we searched for neurological dysfunction with increased s...

journal_title：Acta neurologica Scandinavica

authors： Haghighi S,Frisén L,Odén A,Andersen O

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVES:We performed nerve conduction and needle electromyographic tests in 29 patients with spastic cerebral palsy (SCP) and severe limb deformities. Nerve conduction abnormalities were detected in 32 of 400 sensory or motor nerves, while 11 of 29 patients (37.9%) showed abnormal nerve conduction, indicating one or...

journal_title：Acta neurologica Scandinavica

authors： Frascarelli M,Frascarelli F,Gentile MG,Serrao M,De Santis F,Pierelli F,Santilli V

更新日期：2005-09-01 00:00:00