The opioid system in cardiac and vascular regulation of normal and hypertensive states.

abstract：:This study explored the association between sodium excretion and blood pressure (BP). A new method was used to minimize the measurement error introduced by the large intrinsic variability of 24-hour sodium excretion. The ratio of intra- to interindividual variation was used to estimate the number of measurements neede...

journal_title：Circulation

authors： Cooper R,Soltero I,Liu K,Berkson D,Levinson S,Stamler J

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:The clinical significance of the interaction between clopidogrel and proton pump inhibitors (PPIs) remains unclear. METHODS AND RESULTS:We examined the relationship between PPI use and 1-year cardiovascular events (cardiovascular death, myocardial infarction, or stroke) in patients with acute coronary syndr...

journal_title：Circulation

authors： Goodman SG,Clare R,Pieper KS,Nicolau JC,Storey RF,Cantor WJ,Mahaffey KW,Angiolillo DJ,Husted S,Cannon CP,James SK,Kilhamn J,Steg PG,Harrington RA,Wallentin L,Platelet Inhibition and Patient Outcomes Trial Investigators.

更新日期：2012-02-28 00:00:00

abstract：:The movements of the mitral, tricuspid and aortic valves have been recorded echocardiographically and related to the first heart sound (S1) in patients with various hemodynamic and conduction abnormalities. Closure of the mitral and tricuspid valves has been studied with respect to the corresponding atrioventricular p...

journal_title：Circulation

authors： Mills PG,Chamusco RF,Moos S,Craige E

更新日期：1976-12-01 00:00:00

abstract：:Prognostic stratification was carried out on 518 patients less than or equal to 65 years of age who were discharged from the hospital following a definite or probable acute myocardial infarction and followed for four months. The total population was made up of 272 patients hospitalzed in 1973 and 246 patients hospital...

journal_title：Circulation

authors： Moss AJ,DeCamilla J,Davis H,Bayer L

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:Anecdotal cases of familial clustering of peripartum cardiomyopathy (PPCM) and familial occurrences of PPCM and idiopathic dilated cardiomyopathy (DCM) together have been observed, suggesting that genetic factors play a role in the pathogenesis of PPCM. We hypothesized that some cases of PPCM are part of the...

journal_title：Circulation

authors： van Spaendonck-Zwarts KY,van Tintelen JP,van Veldhuisen DJ,van der Werf R,Jongbloed JD,Paulus WJ,Dooijes D,van den Berg MP

更新日期：2010-05-25 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-alpha (TNF-alpha) has been implicated in the pathogenesis of dilated cardiomyopathy (DCM). TNF-alpha-converting enzyme (TACE) has recently been purified and its complementary DNA cloned. The expression of TACE results in the production of a functional enzyme that has precursor TNF-alpha...

journal_title：Circulation

authors： Satoh M,Nakamura M,Saitoh H,Satoh H,Maesawa C,Segawa I,Tashiro A,Hiramori K

更新日期：1999-06-29 00:00:00

abstract：BACKGROUND:Monocarboxylate transporters (MCTs) mediate lactate transport across the plasma membrane of cells. The molecular mechanisms regulating monocarboxylate transport in smooth muscle cells (SMCs) remain poorly characterized. The aim of this study was to investigate the effects of DNA methylation on MCT expression...

journal_title：Circulation

authors： Zhu S,Goldschmidt-Clermont PJ,Dong C

更新日期：2005-08-30 00:00:00

abstract：BACKGROUND:While previous clinical studies have shown a possible beneficial effect of the reperfusion performed at a relatively late phase of acute myocardial infarction ("late reperfusion") in preventing left ventricular enlargement, the mechanism has not been clarified. METHODS AND RESULTS:Of 89 patients with an ini...

journal_title：Circulation

authors： Hirayama A,Adachi T,Asada S,Mishima M,Nanto S,Kusuoka H,Yamamoto K,Matsumura Y,Hori M,Inoue M

更新日期：1993-12-01 00:00:00

abstract：:This study describes the efficacy of the right gastroepiploic artery (GEA) as graft material for coronary artery bypass grafting (CABG) as assessed by exercise thallium 201 myocardial scintigraphy in eight patients (age, 59.4 +/- 9.35 years [mean +/- SD]) who underwent CABG with the GEA graft in the past 2 years. Plan...

journal_title：Circulation

authors： Kusukawa J,Hirota Y,Kawamura K,Suma H,Takeuchi A,Adachi I,Akagi H

更新日期：1989-09-01 00:00:00

abstract：:Heart-lung transplantation results in afferent and efferent denervation of the transplanted organs including interruption of the central connections from the low-pressure receptors in the atria and pulmonary veins. We investigated whether the cardiovascular and neurohumoral responses to the postural stimulus of head-u...

journal_title：Circulation

authors： Banner NR,Williams TD,Patel N,Chalmers J,Lightman SL,Yacoub MH

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) mass is an important predictor of heart failure and cardiovascular mortality, yet determinants of LV mass are incompletely understood. Pulmonary hyperinflation in chronic obstructive pulmonary disease (COPD) may contribute to changes in intrathoracic pressure that increase LV wall stres...

journal_title：Circulation

authors： Smith BM,Kawut SM,Bluemke DA,Basner RC,Gomes AS,Hoffman E,Kalhan R,Lima JA,Liu CY,Michos ED,Prince MR,Rabbani L,Rabinowitz D,Shimbo D,Shea S,Barr RG

更新日期：2013-04-09 00:00:00

abstract：:Ten patients with the long QT syndrome and recurrent syncope and/or cardiac arrest caused by ventricular arrhythmias underwent left stellate (one patient) or left cervicothoracic sympathectomy (nine patients) after failing to respond to high-dose beta-blocker therapy. The syndrome was familial in four and idiopathic i...

journal_title：Circulation

authors： Bhandari AK,Scheinman MM,Morady F,Svinarich J,Mason J,Winkle R

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:An objective of the United States' Healthy People 2010 Initiative is to eliminate disparities based on socioeconomic status. We assessed the effect of difficulty affording health care on the health status (symptoms, function, and quality of life) of patients treated with percutaneous coronary intervention or...

journal_title：Circulation

authors： Spertus J,Decker C,Woodman C,House J,Jones P,O'Keefe J,Borkon AM

更新日期：2005-05-24 00:00:00

abstract：:The sensitivity of the baroreceptor reflex in nine patients with borderline hypertension (mean age 19.1 plus or minus 0.2 years) was compared to that in six normal subjects of comparable age (mean 18.8 plus or minus 0.3 years) and that in 14 patients with established hypertension (mean age 48.3 plus or minus 3.1 years...

journal_title：Circulation

authors： Takeshita A,Tanaka S,Kuroiwa A,Nakamura M

更新日期：1975-04-01 00:00:00

abstract：:Two hundred-three patients had -echnetium 99m (stannous) pyrophosphate myocardial scintigrams for the evaluation of chest pain and suspected acute myocardial infarction. In addition to routine imaging at 60--90 minutes after injection of the radio-pharmaceutical, the blood pool was imaged immediately in each patient f...

journal_title：Circulation

authors： Cowley MJ,Mantle JA,Rogers WJ,Russel RO Jr,Rackley CE,Logic JR

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Impaired endothelium-dependent, nitric oxide (NO)-mediated vasodilation may contribute to increased vasomotor tone in patients with heart failure. Whether decreased endothelium-dependent, NO-mediated vasodilation in patients with heart failure is due to decreased synthesis or increased degradation of NO is u...

journal_title：Circulation

authors： Katz SD,Khan T,Zeballos GA,Mathew L,Potharlanka P,Knecht M,Whelan J

更新日期：1999-04-27 00:00:00

abstract：BACKGROUND:Biological pacemakers (BPM) implanted in canine left bundle branch function competitively with electronic pacemakers (EPM). We hypothesized that BPM engineered with the use of mE324A mutant murine HCN2 (mHCN2) genes would improve function over mHCN2 and that BPM/EPM tandems confer advantage over either appro...

journal_title：Circulation

authors： Bucchi A,Plotnikov AN,Shlapakova I,Danilo P Jr,Kryukova Y,Qu J,Lu Z,Liu H,Pan Z,Potapova I,KenKnight B,Girouard S,Cohen IS,Brink PR,Robinson RB,Rosen MR

更新日期：2006-09-05 00:00:00

abstract：:A 58-year-old man with hypertensive cardiovascular disease and atrial flutter underwent electrophysiologic studies, including multiple intra-atrial recordings and atrial stimulation. Although the surface ECG suggested the presence of atrial flutter, intra-atrial recordings demonstrated the presence of (1) sinus-like r...

journal_title：Circulation

authors： Gomes JA,Kang PS,Matheson M,Gough WB Jr,El-Sherif N

更新日期：1981-01-01 00:00:00

abstract：:In a double-blind randomized trial involving five Sydney hospitals and the city ambulance paramedical service, 145 patients with a first evolving myocardial infarction and with onset of pain less than 2.5 (mean 1.9 +/- 0.5 [SD]) hr previously were allocated to intravenous infusion of 100 mg recombinant tissue-type pla...

journal_title：Circulation

authors： O'Rourke M,Baron D,Keogh A,Kelly R,Nelson G,Barnes C,Raftos J,Graham K,Hillman K,Newman H

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Mechanical dyssynchrony is a potential means to predict response to cardiac resynchronization therapy (CRT). We hypothesized that novel echocardiographic image speckle tracking can quantify dyssynchrony and predict response to CRT. METHODS AND RESULTS:Seventy-four subjects were studied: 64 heart failure pat...

journal_title：Circulation

authors： Suffoletto MS,Dohi K,Cannesson M,Saba S,Gorcsan J 3rd

更新日期：2006-02-21 00:00:00

abstract：BACKGROUND:Postmortem interrogations of cardiac implantable electronic devices (CIEDs), recommended at autopsy in suspected cases of sudden cardiac death, are rarely performed, and data on systematic postmortem CIED analysis in the forensic pathology are missing. The aim of the study was to determine whether nonselecti...

journal_title：Circulation

authors： Lacour P,Buschmann C,Storm C,Nee J,Parwani AS,Huemer M,Attanasio P,Boldt LH,Rauch G,Kucher A,Pieske B,Haverkamp W,Blaschke F

更新日期：2018-06-19 00:00:00

abstract：BACKGROUND:Single premature beats were introduced in the reentrant circuit during stable atrial flutter in the canine sterile pericarditis model to test the hypotheses that (1) despite the fact that the reentrant circuit is functionally determined, there is a fully excitable gap; (2) the excitable gap in the reentrant ...

journal_title：Circulation

authors： Niwano S,Ortiz J,Abe H,Gonzalez X,Rudy Y,Waldo AL

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Because of the marked difference in the incidence and severity of cardiovascular diseases between men and premenopausal women, several groups have studied the effect of sex steroids, particularly estrogen, on vascular endothelial prostacyclin (PGI2) release. No previous studies have addressed the effect of e...

journal_title：Circulation

authors： Redmond EM,Cherian MN,Wetzel RC

更新日期：1994-11-01 00:00:00

abstract：:We studied six patients who suffered from angina pectoris but had angiographically patent major coronary arteries. Two of the patients suffered also from congestive heart failure. Three patients had supraventricular tachyarrhythmias. Three patients had conduction disturbances. During coronary angiography the patients ...

journal_title：Circulation

authors： Mosseri M,Yarom R,Gotsman MS,Hasin Y

更新日期：1986-11-01 00:00:00

abstract：:We have applied the new technique of dual echocardiography to determine the sequence of atrial contraction as reflected in the simultaneously recorded movements of the tricuspid and mitral valves. The study group included 29 normal subjects and 23 patients with either atrial flutter, coarse atrial fibrillation or atri...

journal_title：Circulation

authors： Fujii J,Foster JR,Mills PG,Moos S,Craige E

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:The role of valve surgery in left-sided infective endocarditis has not been evaluated in randomized controlled trials. We examined the association between valve surgery and all-cause 6-month mortality among patients with left-sided infective endocarditis. METHODS AND RESULTS:A total of 546 consecutive patie...

journal_title：Circulation

authors： Tleyjeh IM,Ghomrawi HM,Steckelberg JM,Hoskin TL,Mirzoyev Z,Anavekar NS,Enders F,Moustafa S,Mookadam F,Huskins WC,Wilson WR,Baddour LM

更新日期：2007-04-03 00:00:00

abstract：BACKGROUND:In patients with mitral stenosis, reduced cardiac output or altered pulmonary hemodynamics may increase sympathetic nerve activity. However, the magnitude of the increase in sympathetic activity in such patients and the effect of valvuloplasty on this activity are unknown. METHODS AND RESULTS:We microneurog...

journal_title：Circulation

authors： Ashino K,Gotoh E,Sumita S,Moriya A,Ishii M

更新日期：1997-11-18 00:00:00

abstract：BACKGROUND:The relations of plasma activated factor XII (FXIIa) concentration and a common polymorphism (C46T) of the factor XII gene with hemostatic status and risk of coronary heart disease (CHD) were examined by prospective surveillance. METHODS AND RESULTS:Genotyping for the C46T variant was performed in 2624 men ...

journal_title：Circulation

authors： Zito F,Drummond F,Bujac SR,Esnouf MP,Morrissey JH,Humphries SE,Miller GJ

更新日期：2000-10-24 00:00:00

abstract：BACKGROUND:Pulmonary hypertension caused by systolic left ventricular dysfunction is associated with significant morbidity and mortality; however, no treatment is approved for this indication. We hypothesized that riociguat, a novel soluble guanylate cyclase stimulator, would have beneficial hemodynamic effects in pati...

journal_title：Circulation

authors： Bonderman D,Ghio S,Felix SB,Ghofrani HA,Michelakis E,Mitrovic V,Oudiz RJ,Boateng F,Scalise AV,Roessig L,Semigran MJ,Left Ventricular Systolic Dysfunction Associated With Pulmonary Hypertension Riociguat Trial (LEPHT) Study Group.

更新日期：2013-07-30 00:00:00

abstract：BACKGROUND:Endothelial progenitor cells (EPCs) circulate in adult peripheral blood (PB) and contribute to neovascularization. However, little is known regarding whether EPCs and their putative precursor, CD34-positive mononuclear cells (MNC(CD34+)), are mobilized into PB in acute ischemic events in humans. METHODS AND...

journal_title：Circulation

authors： Shintani S,Murohara T,Ikeda H,Ueno T,Honma T,Katoh A,Sasaki K,Shimada T,Oike Y,Imaizumi T

更新日期：2001-06-12 00:00:00