Tracheal versus intravenous atropine. A comparison of the effects on heart rate.

Abstract:

:Atropine 600 micrograms was given either intravenously or intratracheally and the change in heart rate noted in a double-blind, randomised study of 40 anaesthetised patients. There was no significant difference between the two groups in the maximum increase in heart rate, 20.3 beats/minute in the tracheal compared to 21.4 beats/minute in the intravenous group. However, the maximum increase occurred significantly earlier in the tracheal group, 45.5 seconds after administration compared to 95.5 seconds in the intravenous group (p less than 0.01, 95% confidence interval 36.8-63.2 seconds). This study supports the clinical observation that tracheal and intravenous atropine are equally effective and suggests that the trachea should be the route of choice when a rapid response is required.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Bray BM,Jones HM,Grundy EM

doi

10.1111/j.1365-2044.1987.tb05226.x

subject

Has Abstract

pub_date

1987-11-01 00:00:00

pages

1188-90

issue

11

eissn

0003-2409

issn

1365-2044

journal_volume

42

pub_type

临床试验,杂志文章,随机对照试验
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    journal_title:Anaesthesia

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    pub_type: 临床试验,杂志文章,随机对照试验

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    pub_type: 临床试验,杂志文章,随机对照试验

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  • A comparison of low vs conventional-dose heparin for minimal cardiopulmonary bypass in coronary artery bypass grafting surgery.

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    pub_type: 传,历史文章,杂志文章

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