Glycopyrrolate: pharmacology and clinical use.

abstract：:The measurement of gastric intramucosal pH serves as a non-invasive technique for early detection of gastrointestinal ischaemia in critically ill patients. The method is based on the determination of the partial pressure of carbon dioxide in a 0.9% saline solution using a standard blood gas analyser. However, the use ...

journal_title：Anaesthesia

authors： Knichwitz G,Mertes N,Kuhmann M

更新日期：1995-06-01 00:00:00

abstract：:J waves appear on an electrocardiogram as an elevation of the J point in the terminal portion of the QRS complex. J waves are often benign, but may be associated with malignant ventricular arrhythmias. In some cases, such problems appear to have been precipitated by propofol infusions. We observed a sudden increase in...

journal_title：Anaesthesia

authors： Takaishi K,Kawahito S,Yamada H,Soeki T,Sata M,Kitahata H

更新日期：2014-02-01 00:00:00

abstract：:In a well-defined fast-track setup for total hip and knee arthroplasty, with a multimodal analgesic regimen consisting of intra-operative local anaesthetic infiltration and oral celecoxib, gabapentin and paracetamol for 6 days postoperatively, we conducted a prospective, consecutive, observational study. The purpose w...

journal_title：Anaesthesia

authors： Andersen LØ,Gaarn-Larsen L,Kristensen BB,Husted H,Otte KS,Kehlet H

更新日期：2009-05-01 00:00:00

abstract：:Ketamine and midazolam were used for induction of anaesthesia and by continuous intravenous infusion for maintenance to assess their suitability for use in a total intravenous anaesthetic technique in the management of battle casualties. Muscular relaxation was provided by vecuronium and the patients' lungs ventilated...

journal_title：Anaesthesia

authors： Restall J,Tully AM,Ward PJ,Kidd AG

更新日期：1988-01-01 00:00:00

abstract：:Traditional medical decision making is unstructured and incorporates evidence haphazardly. I present a more structured approach based on decision analysis, a model that considers all relevant options and outcomes informed by evidence where appropriate. This method is useful both for planning clinical management and fo...

journal_title：Anaesthesia

authors： Yentis SM

更新日期：2006-07-01 00:00:00

abstract：:Propofol and thiopentone were compared as anaesthetic agents for electroconvulsive therapy in 31 patients on four occasions in a repeated measure crossover study. Discomfort on injection was significantly more common with propofol (51.6% of anaesthetics) compared to thiopentone (1.6% of anaesthetics). The duration of ...

journal_title：Anaesthesia

authors： Boey WK,Lai FO

更新日期：1990-08-01 00:00:00

abstract：:We compared the pharmacokinetics, pharmacodynamics and safety profile of a new galenic formulation of propofol (AM149 1%), which does not contain soyabean oil, with a standard formulation of propofol (Disoprivan 1%). In a randomised, double-blind, cross-over study, 30 healthy volunteers received a single intravenous b...

journal_title：Anaesthesia

authors： Paul M,Dueck M,Kampe S,Fruendt H,Kasper SM

更新日期：2003-11-01 00:00:00

abstract：:The Confidential Enquiries into Maternal Deaths in the UK have recommended obstetric early warning systems for early identification of clinical deterioration to reduce maternal morbidity and mortality. This survey explored early warning systems currently used by maternity units in the UK. An electronic questionnaire w...

journal_title：Anaesthesia

authors： Isaacs RA,Wee MY,Bick DE,Beake S,Sheppard ZA,Thomas S,Hundley V,Smith GB,van Teijlingen E,Thomas PW,Members of the Modified Obstetric Early Warning Systems Research Group.

更新日期：2014-07-01 00:00:00

abstract：:The natural history diagnosis and immediate treatment of patients suffering from pulmonary embolism has been discussed. Anaesthetists should use their influence to bring about a high standard of prophylactic care against deep venous thrombosis and consequently of pulmonary embolism. They are likely to be involved in t...

journal_title：Anaesthesia

authors： Price DG

更新日期：1976-09-01 00:00:00

abstract：:The effects of a sedative infusion of propofol on haemodynamics and oxygen transport were examined in critically ill adult patients. Ten patients receiving mechanical ventilation for treatment of septic shock and respiratory failure were given a decreasing rate propofol infusion designed to achieve and maintain a stab...

journal_title：Anaesthesia

authors： Nimmo GR,Mackenzie SJ,Grant IS

更新日期：1994-06-01 00:00:00

abstract：:Although several local anaesthetic techniques are described for nasal analgesia during awake intubation, there has been little attempt to evaluate their effectiveness. We examined pain scores associated with nasal intubation in a randomised cross-over study of 25 volunteers. Local anaesthesia consisted of topical aero...

journal_title：Anaesthesia

authors： Cara DM,Norris AM,Neale LJ

更新日期：2003-08-01 00:00:00

abstract：:Propofol is the most commonly administered intravenous agent for anaesthesia in children. However, there are concerns that the emulsified preparation may not be safe in children with an allergy to egg, peanut, soybean or other legumes. We conducted a retrospective study of children with immunologically confirmed egg, ...

journal_title：Anaesthesia

authors： Sommerfield DL,Lucas M,Schilling A,Drake-Brockman TFE,Sommerfield A,Arnold A,von Ungern-Sternberg BS

更新日期：2019-10-01 00:00:00

abstract：:An internal jugular catheter, which was inserted into a patient with a traumatic haemopneumothorax, accidentally entered the pleural cavity. This was initially undetected because the two signs most frequently used to confirm correct placement, those of blood reflux and fluctuation of central venous pressure with respi...

journal_title：Anaesthesia

authors： Pina J,Morujão N,Castro-Tavares J

更新日期：1992-01-01 00:00:00

abstract：:Forty-seven children aged between four and 11 years received temazepam 0.5 mg/kg in a novel fast dispensing dosage form. The preparation was well accepted and associated with few side-effects. Satisfactory sedation and anxiolysis was obtained in over 93% of patients. The relative merits of a variety of routes of admin...

journal_title：Anaesthesia

authors： Smith GB,Hughes DG,Kumar V

更新日期：1985-04-01 00:00:00

abstract：:To assess the utility of a relatively simple bedside method of estimating cardiac index during major surgery or in the intensive care unit, we conducted a prospective study in patients undergoing elective cardiac bypass surgery where a pulmonary artery catheter was inserted as part of routine monitoring. The cardiac i...

journal_title：Anaesthesia

authors： Berridge JC,Warring-Davies K,Bland JM,Quinn AC

更新日期：2009-09-01 00:00:00

abstract：:Free radical species are ubiquitous in plant and animal life. This article describes briefly the formation of certain oxygen-centred free radicals which are essential for aerobic metabolism and host defences in humans. The mechanism of cytotoxicity of excess or inappropriate free radical production is described. The p...

journal_title：Anaesthesia

authors： Royston D

更新日期：1988-04-01 00:00:00

abstract：:The efficacy and safety of remifentanil and alfentanil for patients undergoing major abdominal surgery were compared. Premedicated patients received a loading dose of remifentanil (1.0 microgram.kg-1; n = 116) and a continuous infusion of 0.5 microgram.kg-1.min-1, or a loading dose of alfentanil (25 micrograms.kg-1; n...

journal_title：Anaesthesia

authors： Schüttler J,Albrecht S,Breivik H,Osnes S,Prys-Roberts C,Holder K,Chauvin M,Viby-Mogensen J,Mogensen T,Gustafson I,Lof L,Noronha D,Kirkham AJ

更新日期：1997-04-01 00:00:00

abstract：:The use of a portable generator which liberates oxygen from hydrogen peroxide solutions has been investigated in veterinary anaesthesia to assess its potential as an alternative to conventional oxygen supplies both in emergency situations and in the event of failure of cylinder systems. The reliability of the supply a...

journal_title：Anaesthesia

authors： Hall LW,Kellagher RE,Fleet KJ

更新日期：1986-05-01 00:00:00

abstract：:The preferences of 118 elderly patients, aged from 70 to 97 years, concerning the institution of artificial ventilation in the event of an overwhelming illness, were investigated using a questionnaire. Most patients wanted treatment if the outcome was likely to be good, but in approximately half, the desire for treatm...

journal_title：Anaesthesia

authors： Heap MJ,Munglani R,Klinck JR,Males AG

更新日期：1993-12-01 00:00:00

abstract：:This study evaluated if adding low-dose ketamine to fentanyl could offer a haemodynamically stable drug combination with little respiratory side-effects. Eight healthy, consenting male volunteers received in a random, cross-over and double-blind fashion both fentanyl 2 micrograms.kg-1 + ketamine 0.25 mg.kg-1 and fenta...

journal_title：Anaesthesia

authors： Mildh L,Taittonen M,Leino K,Kirvelä O

更新日期：1998-10-01 00:00:00

abstract：:Citrate, as an anticoagulant for continuous renal replacement therapy in critically ill patients, has some potential advantages over heparin, including a prolonged dialysis filter life and reduced risk of bleeding. The key parameter involved in monitoring the adequacy and safety of citrate anticoagulation during conti...

journal_title：Anaesthesia

authors： Morgan DJ,Ho KM

更新日期：2009-12-01 00:00:00

abstract：:Harold King was an analytical chemist of distinction, who worked with Sir Henry Dale and his colleagues in the Medical Research Institute, later the Medical Research Council. He helped to quash the theory that the anaesthetic action of ether was attributable to its impurities. Interest in alkaloids led to the elucidat...

journal_title：Anaesthesia

authors： Gray TC

更新日期：1991-08-01 00:00:00

abstract：:Intra-ocular pressure was measured before and throughout airway establishment with either the laryngeal mask airway or tracheal tube. Similar measurements were made on removal of either airway and the amount of coughing noted in the first minute after removal. There was a significantly smaller increase in intra-ocular...

journal_title：Anaesthesia

authors： Holden R,Morsman CD,Butler J,Clark GS,Hughes DS,Bacon PJ

更新日期：1991-11-01 00:00:00

abstract：:Although epidural analgesia is routinely used in many institutions for patients undergoing hepatic resection, there are unresolved issues regarding its safety and efficacy in this setting. We performed a review of papers published in the area of anaesthesia and analgesia for liver resection surgery and selected four a...

journal_title：Anaesthesia

authors： Tzimas P,Prout J,Papadopoulos G,Mallett SV

更新日期：2013-06-01 00:00:00

abstract：:The present study was conducted with the aims of comparing intravenous tramadol 1, 2 and 3 mg.kg(-1) with pethidine 0.5 mg.kg(-1) for prophylaxis of postanaesthetic shivering and to find a dose of tramadol that could provide the dual advantage of antishivering and analgesic effect in the postoperative period. The stud...

journal_title：Anaesthesia

authors： Mohta M,Kumari N,Tyagi A,Sethi AK,Agarwal D,Singh M

更新日期：2009-02-01 00:00:00

abstract：:The efficacy of thoracic epidural sufentanil 50 micrograms was compared with lumbar epidural sufentanil 50 micrograms in 30 patients (n = 15 in each group) undergoing lateral thoracotomy. Sufentanil was administered epidurally after induction of anaesthesia with sufentanil 1 microgram.kg-1 and thiopentone 2-5 mg.kg-1 ...

journal_title：Anaesthesia

authors： Haak-van der Lely F,van Kleef JW,Burm AG,Bovill JG

更新日期：1994-02-01 00:00:00

abstract：SUMMARY:In a randomised, double-blinded study, we compared boluses of phenylephrine 100 microg with ephedrine 10 mg for treating hypotension (systolic blood pressure < 100 mmHg) in 204 patients having non-elective Caesarean section under spinal anaesthesia. Umbilical arterial (UA) and venous (UV) pH and base excess wer...

journal_title：Anaesthesia

authors： Ngan Kee WD,Khaw KS,Lau TK,Ng FF,Chui K,Ng KL

更新日期：2008-12-01 00:00:00

abstract：:We have compared the performance of the Baxter disposable with the Graseby electronic patient-controlled analgesia system in 30 patients following major gynaecological surgery. Patients were allocated randomly to receive analgesia via the Baxter or Graseby device for postoperative pain relief. There were no significan...

journal_title：Anaesthesia

authors： Robinson SL,Rowbotham DJ,Mushambi M

更新日期：1992-02-01 00:00:00

abstract：:The Portex introducer for the laryngeal mask airway was designed as an aid to successful insertion, acting as an idealised 'artificial hard palate' to guide the tip of the laryngeal mask into the correct position. A number of authors have investigated laryngeal mask insertion by unskilled personnel in certain situatio...

journal_title：Anaesthesia

authors： Dingley J,Baynham P,Swart M,Vaughan RS

更新日期：1997-08-01 00:00:00

abstract：:We assessed adequacy of ventilation in 20 critically ill patients with multiple organ failure using a Pneupac Ventipac portable ventilator and the effects on patients' haemodynamic stability. Baseline data were recorded over 15 min for a range of respiratory, haemodynamic and oxygen transport variables during ventilat...

journal_title：Anaesthesia

authors： McCluskey A,Gwinnutt CL,Hardy L,Haslett R,Bowles B,Kishen R

更新日期：2001-11-01 00:00:00