A Pilot Study of the Efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Treating Posttraumatic Psychopathology: A Randomized Controlled Trial.

Abstract:

:The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) is an intervention that targets common mechanisms that maintain symptoms across multiple disorders. The UP has been shown to be effective across many disorders, including generalized anxiety disorder, major depressive episode (MDE), and panic disorder, that commonly codevelop following trauma exposure. The present study represented the first randomized controlled trial of the UP in the treatment of trauma-related psychopathology, including posttraumatic stress disorder (PTSD), depression, and anxiety symptoms. Adults (N = 43) who developed posttraumatic psychopathology that included PTSD, MDE, or an anxiety disorder after sustaining a severe injury were randomly assigned to receive 10-14 weekly, 60-min sessions of UP (n = 22) or usual care (n = 21). The primary treatment outcome was PTSD symptom severity, with secondary outcomes of depression and anxiety symptom severity and loss of diagnosis for any trauma-related psychiatric disorder. Assessments were conducted at intake, posttreatment, and 6-month follow-up. Posttreatment, participants who received the UP showed significantly larger reductions in PTSD, Hedges' g = 1.27; anxiety, Hedges' g = 1.20; and depression symptom severity, Hedges' g = 1.40, compared to those receiving usual care. These treatment effects were maintained at 6-month follow-up for PTSD, anxiety, and depressive symptom severity. Statistically significant posttreatment loss of PTSD, MDE, and agoraphobia diagnoses was observed for participants who received the UP but not usual care. This study provides preliminary evidence that the UP may be an effective non-trauma-focused treatment for PTSD and other trauma-related psychopathology.

journal_name

J Trauma Stress

authors

O'Donnell ML,Lau W,Chisholm K,Agathos J,Little J,Terhaag S,Brand R,Putica A,Holmes ACN,Katona L,Felmingham KL,Murray K,Hosseiny F,Gallagher MW

doi

10.1002/jts.22650

subject

Has Abstract

pub_date

2021-01-16 00:00:00

eissn

0894-9867

issn

1573-6598

pub_type

杂志文章
  • Resource Loss and Stress Outcomes in a Setting of Chronic Conflict: The Conservation of Resources Theory in the Eastern Congo.

    abstract::The purpose of this cross-sectional study was to examine conservation of resources (COR) theory in the context of armed conflict in Africa. Specifically, within the setting of ongoing chronic conflict in the eastern Democratic Republic of the Congo (DRC), we tested the COR theory prediction that resource loss contribu...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.22448

    authors: Snyder JD,Boan D,Aten JD,Davis EB,Van Grinsven L,Liu T,Worthington EL Jr

    更新日期:2020-06-01 00:00:00

  • Suicidal behavior after severe trauma. Part 2: The association between methods of torture and of suicidal ideation in posttraumatic stress disorder.

    abstract::The study reports on 65 refugees with diagnoses of posttraumatic stress disorder (PTSD) and manifest suicidal behavior (40% had suicide attempts; 29% detailed suicide plan; 31% recurrent suicidal thoughts). Our hypothesis was that the predominant kind of stressful experience in PTSD patients might be reflected in thei...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1023/A:1024413301064

    authors: Ferrada-Noli M,Asberg M,Ormstad K

    更新日期:1998-01-01 00:00:00

  • "I felt like a slut": the cultural context and women's response to being raped.

    abstract::This paper examines how cultural beliefs (cultural constructions) about women influence how women survivors of rape make sense of their traumatic experience. A thematic content analysis of interviews with female survivors of rape was undertaken to provide a systematic description of the phenomenology of the experience...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1007/BF02102783

    authors: Lebowitz L,Roth S

    更新日期:1994-07-01 00:00:00

  • Exposure to violence and PTSD symptoms among Somali women.

    abstract::Posttraumatic stress disorder (PTSD) symptoms, exposure to traumatic stressors, and health care utilization were examined in 84 women attending a primary health care clinic in Mogadishu, Somalia. The Somalia-Posttraumatic Diagnostic Scale was used in this active warzone to measure symptoms. Nearly all women reported h...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.20694

    authors: de Jong K,van der Kam S,Swarthout T,Ford N,Mills C,Yun O,Kleber RJ

    更新日期:2011-12-01 00:00:00

  • Psychophysiological predictors of working alliance among treatment-seeking women with complex trauma exposure.

    abstract::Research has established that trauma-related symptoms may impede the formation of a strong working alliance (i.e., interpersonal connection, trust, and shared goals between therapist and client). As the alliance is critical in trauma-focused therapy, we studied how clients' pretherapy factors, including symptoms and p...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.21968

    authors: Doukas A,D'Andrea W,Doran J,Pole N

    更新日期:2014-12-01 00:00:00

  • Pathways to Help-Seeking Among Black Male Trauma Survivors: A Fuzzy Set Qualitative Comparative Analysis.

    abstract::Many Black men suffer symptoms of traumatic stress in the aftermath of traumatic injury, and they also often carry social concerns, including experiences of discrimination and stigma, and a lack of financial resources. The objective of the present study was to understand how traumatic symptoms and social factors combi...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.22517

    authors: Rich JA,Corbin TJ,Jacoby SF,Webster JL,Richmond TS

    更新日期:2020-08-01 00:00:00

  • Causes of death among male veterans who received residential treatment for PTSD.

    abstract::Previous studies have shown elevated mortality among psychiatric and substance abusing patients, including veterans with PTSD. Although early studies showed elevated deaths from external causes among Vietnam veterans in the early postwar years, more recent studies have also shown increased health problems among vetera...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1023/B:JOTS.0000004076.62793.79

    authors: Drescher KD,Rosen CS,Burling TA,Foy DW

    更新日期:2003-12-01 00:00:00

  • Are children of Holocaust survivors less well-adapted? A meta-analytic investigation of secondary traumatization.

    abstract::H. Keilson (1979) coined the term "sequential traumatization" for the accumulation of traumatic stresses confronting the Holocaust survivors before, during, and after the war. A central question is whether survivors were able to raise their children without transmitting the traumas of their past. Through a series of m...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章,meta分析

    doi:10.1023/A:1025706427300

    authors: van IJzendoorn MH,Bakermans-Kranenburg MJ,Sagi-Schwartz A

    更新日期:2003-10-01 00:00:00

  • Back to school: review of school based interventions: comment on Rolfsness and Idsoe (2011).

    abstract::We comment on a recently published article in the Journal of Traumatic Stress that reviewed school-based interventions related to trauma. We point out the recent book published by Guilford Press on the International Society for Traumatic Stress Studies Practice Guildelines (2009), which also provides a thorough review...

    journal_title:Journal of traumatic stress

    pub_type: 评论,杂志文章

    doi:10.1002/jts.20702

    authors: Cohen JA,Jaycox LH,Amaya-Jackson L,Stein BD

    更新日期:2011-12-01 00:00:00

  • Validation of the Purdue Post-Traumatic Stress Scale on a sample of Vietnam veterans.

    abstract::The Purdue Post-traumatic Stress Disorder Scale is a 15-item self-report instrument based on the DSM-III diagnostic criteria for post-traumatic stress disorder. This scale is a quick, easily administered, measure of psychological reactions to a traumatic event. The goal of the present report is to validate this instru...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1007/BF02102951

    authors: Hendrix CC,Anelli LM,Gibbs JP,Fournier DG

    更新日期:1994-04-01 00:00:00

  • Associations between perceived social reactions to trauma-related experiences with PTSD and depression among veterans seeking PTSD treatment.

    abstract::The Social Acknowledgment Questionnaire (SAQ; Maercker & Mueller, ) is a measure of trauma survivors' perceptions of social acknowledgment and disapproval from others, and these factors are shown to be associated with posttraumatic stress disorder (PTSD) among civilian trauma survivors. This study seeks to validate th...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.21879

    authors: Schumm JA,Koucky EM,Bartel A

    更新日期:2014-02-01 00:00:00

  • Factor structure of posttraumatic stress among Western New York undergraduates following the September 11th terrorist attack on the World Trade Center.

    abstract::The structure of posttraumatic stress is of both theoretical and clinical interest. In the present study, seven models of posttraumatic stress were compared using confirmatory factor analysis. A sample of 528 Western New York undergraduate students was assessed 1 and 3 months after the September 11th, 2001 terrorist a...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.20076

    authors: Baschnagel JS,O'Connor RM,Colder CR,Hawk LW Jr

    更新日期:2005-12-01 00:00:00

  • Secondary Traumatic Stress in Postdisaster Field Research Interviewers.

    abstract::Numerous studies show that those involved in disaster response may develop posttraumatic stress disorder or experience secondary traumatic stress (STS). There are few reports about the experiences of postdisaster field research interviewers. We report findings from a follow-up study of researchers who conducted postwi...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.22072

    authors: McLennan J,Evans L,Cowlishaw S,Pamment L,Wright L

    更新日期:2016-02-01 00:00:00

  • Trauma associated with civil conflict and posttraumatic stress disorder: evidence from the Northern Ireland study of health and stress.

    abstract::The authors provide epidemiological estimates of trauma, posttraumatic stress disorder (PTSD), and associated mental disorders in Northern Ireland (NI) with a focus on the impact of civil conflict using data from the NI Study of Health and Stress (NISHS), a representative epidemiological survey of adults in NI. Overal...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.21766

    authors: Bunting BP,Ferry FR,Murphy SD,O'Neill SM,Bolton D

    更新日期:2013-02-01 00:00:00

  • Posttraumatic Stress Disorder Symptom Clusters in Service Members Predict New-Onset Depression Among Military Spouses.

    abstract::Military operations in Iraq and Afghanistan have brought increased attention to posttraumatic stress disorder (PTSD) among service members and, more recently, its impact on spouses. Existing research has demonstrated that PTSD among service members is associated with depression among military spouses. In the current s...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.22575

    authors: Walter KH,LeardMann CA,Carballo CE,McMaster HS,Donoho CJ,Stander VA

    更新日期:2020-09-03 00:00:00

  • Dimensional analysis of the Impact of Event Scale using structural equation modeling.

    abstract::The dimensionality of the Impact of Event Scale (IES) was analyzed using structural equation modeling (SEM). Responses from 321 individuals (62% response) who had experienced a mass murder of seven people 8 months earlier were obtained. A model with a general factor and three subordinate specific factors--Intrusivenes...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1023/A:1007798326052

    authors: Larsson G

    更新日期:2000-04-01 00:00:00

  • Sexual Trauma and Combat During Deployment: Associations With Suicidal Ideation Among OEF/OIF/OND Veterans.

    abstract::Compelling evidence has emerged on the association between military sexual trauma and suicide attempt; however, research investigating how sexual trauma during deployment relates to suicidal ideation has received considerably less attention and has yielded mixed findings. Furthermore, such research has not accounted f...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.22018

    authors: Monteith LL,Menefee DS,Forster JE,Wanner JL,Bahraini NH

    更新日期:2015-08-01 00:00:00

  • Mild Traumatic Brain Injury, PTSD, and Psychosocial Functioning Among Male and Female U.S. OEF/OIF Veterans.

    abstract::This study examined the unique and combined relationship between mild traumatic brain injury (mTBI) and posttraumatic stress disorder (PTSD) with psychosocial functioning in a cohort of 1,312 U.S. male and female veterans of Operations Enduring Freedom (OEF) and Iraqi Freedom (OIF) enrolled in the Veterans After-Disch...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.22110

    authors: Jackson CE,Green JD,Bovin MJ,Vasterling JJ,Holowka DW,Ranganathan G,Rosen RC,Keane TM,Marx BP

    更新日期:2016-08-01 00:00:00

  • Human Remains Identification, Grief, and Posttraumatic Stress in Bereaved Family Members 14 Years After the September 11, 2001, Terrorist Attacks.

    abstract::Returning human remains to family members after a loved one's death is thought to support grief adaptation. However, no known research has examined the effects that notifications of fragmented remains have on bereaved family members. We examined the number of notifications received, continuing questions about the deat...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.22548

    authors: Cozza SJ,Fisher JE,Hefner KR,Fetchet MA,Chen S,Zuleta RF,Fullerton CS,Ursano RJ

    更新日期:2020-12-01 00:00:00

  • The latent structure of the Peritraumatic Dissociative Experiences Questionnaire.

    abstract::This paper has been retracted due to a publisher's error: the order of the authors was incorrect. The Editor and Publisher of the Journal of Traumatic Stress apologize to the authors and our readership. The Peritraumatic Dissociative Experiences Questionnaire (PDEQ) is a widely used measure of peritraumatic dissociati...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.20414

    authors: Brooks R,Bryant RA,Silove D,Creamer M,O'Donnell M,McFarlane AC,Marmar CR

    更新日期:2009-04-01 00:00:00

  • Consequences of the Diagnostic Criteria Proposed for the ICD-11 on the Prevalence of PTSD in Children and Adolescents.

    abstract::In 2013, a working group of the World Health Organization (WHO) proposed a reformulation of the posttraumatic stress disorder (PTSD) diagnostic criteria for the upcoming 11(th) edition of the International Classification of Diseases (ICD-11; Maercker, Brewin, Bryant, Cloitre, van Ommeren, et al., 2013). This study inv...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/jts.22080

    authors: Sachser C,Goldbeck L

    更新日期:2016-04-01 00:00:00

  • Putting the Patient Back in Clinical Significance: Moderated Nonlinear Factor Analysis for Estimating Clinically Significant Change in Treatment for Posttraumatic Stress Disorder.

    abstract::The present study introduced a modernized approach to Jacobson and Truax's (1991) methods of estimating treatment effects on individual-level (a) movement from the clinical to the normative range and (b) reliable change on posttraumatic stress disorder (PTSD) severity. Participants were 450 trauma-exposed women (M age...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.22624

    authors: Saavedra LM,Morgan-López AA,Hien DA,Killeen TK,Back SE,Ruglass LM,Fitzpatrick S,Lopez-Castro T

    更新日期:2020-11-11 00:00:00

  • Factor structure and concurrent validity of the world assumptions scale.

    abstract::The factor structure of the World Assumptions Scale (WAS) was assessed by means of confirmatory factor analysis. The sample was comprised of 1,710 participants who had been exposed to trauma that resulted in whiplash. Four alternative models were specified and estimated using LISREL 8.72. A correlated 8-factor solutio...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.20203

    authors: Elklit A,Shevlin M,Solomon Z,Dekel R

    更新日期:2007-06-01 00:00:00

  • Psychosocial Group Intervention Among War-Affected Children: An Analysis of Changes in Posttraumatic Cognitions.

    abstract::Cognitive theories point to reduction in dysfunctional posttraumatic cognitions (PTCs) as one mechanism involved in recovery from posttraumatic stress symptoms (PTSS), yet research findings have shown individual differences in the recovery process. We tested the cognitive mediation hypothesis above in a previously pub...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/jts.22149

    authors: Kangaslampi S,Punamäki RL,Qouta S,Diab M,Peltonen K

    更新日期:2016-12-01 00:00:00

  • Do Holocaust survivors show increased vulnerability or resilience to post-Holocaust cumulative adversity?

    abstract::Prior trauma can hinder coping with additional adversity or inoculate against the effect of recurrent adversity. The present study further addressed this issue by examining whether a subsample of Holocaust survivors and comparison groups, drawn from the Israeli component of the Survey of Health, Ageing, and Retirement...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.20524

    authors: Shrira A,Palgi Y,Ben-Ezra M,Shmotkin D

    更新日期:2010-06-01 00:00:00

  • Stress debriefing and patterns of recovery following a natural disaster.

    abstract::Stress debriefing has been used extensively following traumatic events; however, there is little evidence of its effectiveness. This paper reports the effects of stress debriefing on the rate of recovery of 195 helpers (e.g., emergency service personnel and disaster workers) following an earthquake in Newcastle, Austr...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1007/BF02116832

    authors: Kenardy JA,Webster RA,Lewin TJ,Carr VJ,Hazell PL,Carter GL

    更新日期:1996-01-01 00:00:00

  • Behavioral and molecular genetics of dissociation: the role of the serotonin transporter gene promoter polymorphism (5-HTTLPR).

    abstract::We evaluated the role of the serotonin transporter gene promoter polymorphism (5-HTTLPR) in the etiology of dissociation. Adult twin pairs (N = 184 pairs; mean age 33.0 years, SD = 10.8) completed measures for dissociation and trauma. The DNA samples were genotyped for 5-HTTLPR adjusted for rs25531 alleles. Behavioral...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.20659

    authors: Pieper S,Out D,Bakermans-Kranenburg MJ,van Ijzendoorn MH

    更新日期:2011-08-01 00:00:00

  • Adaptation and psychometric properties of the German version of the Dissociative Experience Scale.

    abstract::We introduce the 'Fragebogen zu Dissoziativen Symptomen' (FDS), a German adaptation of the Dissociative Experience Scale (DES) which was developed to screen for dissociation within an ICD-10 framework. In addition to the original 28 DES items, the FDS contains 16 items covering dissociative phenomena included in the I...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1023/A:1024457819547

    authors: Spitzer C,Freyberger HJ,Stieglitz RD,Carlson EB,Kuhn G,Magdeburg N,Kessler C

    更新日期:1998-10-01 00:00:00

  • Direct and Indirect Effects of Perceived Stigma on Posttraumatic Growth in Gay Men and Lesbian Women in Chile.

    abstract::This study examined the direct and indirect effects of perceived stigma on posttraumatic growth (PTG) in a sample of gay men and lesbian women in Chile, with coping strategies (positive reappraisal, social support seeking, and active coping strategies) as intermediate variables. Data from 467 gay men (57.4%) and lesbi...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.22256

    authors: Cárdenas M,Barrientos J,Meyer I,Gómez F,Guzmán M,Bahamondes J

    更新日期:2018-02-01 00:00:00

  • Development and validation of a new instrument to assess lifetime trauma and victimization history.

    abstract::This article describes a new easy-to-administer and understand, interview-based instrument that systematically and comprehensively assesses a person's Lifetime Trauma and Victimization History (LTVH). The LTVH inquires about 30 traumas and victimization experiences (including general traumas, physical assault/abuse, s...

    journal_title:Journal of traumatic stress

    pub_type: 杂志文章

    doi:10.1002/jts.20060

    authors: Widom CS,Dutton MA,Czaja SJ,DuMont KA

    更新日期:2005-10-01 00:00:00