当前位置： SCI文献检索 > TRANSPLANTATION PROCEEDINGS期刊下所有文献 > Outcomes of simultaneous kidney-pancreas transplantation with positive cross-match.

Outcomes of simultaneous kidney-pancreas transplantation with positive cross-match.

Abstract：

:We studied 72 consecutive simultaneous pancreas kidney transplant (SPKT) recipients. There were 14 patients with positive pretransplant cross-matches (positive CDC- B cell and/or positive flow T or B cross-match). The control group included all 58 SPKT recipients with a negative crossmatch. The study group received induction with low dose intravenous immunoglobulin (IVIg), rabbit antithymocyte globulin (rATG; total dose 6 mg/kg), or alemtuzumab (30 mg single dose) and maintenance with tacrolimus, mycophenolate mofetil (MMF), and corticosteroids. The control group was treated similarly, but with steroid avoidance and no IVIg. Biopsy-proven acute rejection (BPAR) of the kidney allograft occurred in 7 study patients (50%) compared with 10% in the control group (P = .022). One patient experienced acute cellular rejection (ACR); the other 6 (43%), antibody-mediated rejection (AMR). None of the cross-match negative patients had AMR (P = .001). The mean follow-up period was 18.7 months in the study group, and 18.3 months in the control group. The 1-year actuarial patient survival was 91.7% in the study group and 97% in the control group. Kidney allograft survival was 91.7% in the study group and 95.2% in the control group. Pancreas allograft survival was 76.9% in study group and 89.6% in the control group (P = .088). We concluded that patients with a positive pretransplant CDC-B cross-match and/or positive flow cross-match have an increased risk of AMR; more intensive desensitization is needed with low-dose IVIg and induction with either rATG or alemtuzumab.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Heilman RL,Chakkera H,Mazur M,Petrides S,Moss A,Mekeel K,Mulligan D,Reddy KS

doi

10.1016/j.transproceed.2008.08.154

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

303-6

issue

1

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(08)01615-1

journal_volume

41

pub_type

杂志文章

相关文献

TRANSPLANTATION PROCEEDINGS文献大全
  • Excellent long-term results in de novo renal transplant recipients treated with proliferation signal inhibitors and reduced calcineurin inhibitors exposure.

    abstract：BACKGROUND:A new class of immunosuppressants, proliferation signal inhibitors (PSI)--sirolimus and everolimus--has the potential to prevent chronic allograft nephropathy (CAN). This retrospective analysis reports a 6-year practice using PSI at a single center, comparing a regimen based on reduced-dose calcineurin inhib...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.05.047

    authors： Carmellini M,Collini A,Ruggieri G,Garosi G,Bernini M

    更新日期：2008-07-01 00:00:00

  • Genitourinary Tract Infection Due to Mycobacterium avium intracellulare Complex Infection in Pretransplant Setting With Recurrence Following Transplant: A Case Report.

    abstract：:Genitourinary (GU) tract infection with Mycobacterium avium intracellulare complex (MAI) is very rare and, to our knowledge, has never been reported in the solid organ transplant literature. CASE DESCRIPTION: A 61-year-old Somali-born woman had a history of liver cirrhosis due to chronic hepatitis C infection. She was...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2018.09.007

    authors： Obeid KM,Hassan MA,Chinnakotla S,Young JH

    更新日期：2018-12-01 00:00:00

  • Bile CXC motif chemokine 10 levels correlate with anti-donor cytotoxic T cell responses after liver transplantation.

    abstract：BACKGROUND:CXC motif chemokine 10 (CXCL10), known as interferon-γ-induced protein 10, is an inflammatory cytokine secreted by various cells in response to interferon-γ. CXCR3, the receptor of CXCL10, is predominantly expressed on activated T, B, natural killer, and dendritic cells, as well as macrophages. CXCR3 promote...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2013.11.092

    authors： Morimoto H,Ide K,Tanaka Y,Ishiyama K,Ohira M,Tahara H,Teraoka Y,Yamashita M,Abe T,Hashimoto S,Hirata F,Tanimine N,Saeki Y,Shimizu S,Sakai H,Yano T,Tashiro H,Ohdan H

    更新日期：2014-04-01 00:00:00

  • The proteasome inhibitor bortezomib inhibits intimal hyperplasia of autologous vein grafting in rat model.

    abstract：OBJECTIVE:Increasing evidence indicates that inflammation plays an important role in intimal hyperplasia (IH) induced by autologous vein grafts. The proteasome inhibitor bortezomib shows anti-inflammatory effects, so we used an autologous vein transplantation model to test whether bortezomib inhibits neointimal formati...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.01.063

    authors： He XP,Li XX,Bi YW,Yue WM,Sun WY,Pang XY,Gu XH

    更新日期：2008-06-01 00:00:00

  • Modified liver-free multivisceral transplantation for a metastatic small bowel neuroendocrine tumor: a case report.

    abstract：:Neuroendocrine tumors originating from the small bowel frequently metastasize to the lymph nodes and/or liver. Although surgical extirpation of the primary tumor and locoregional metastases epitomizes the management of patients with such tumors, this is not always possible with conventional surgical techniques. Nonres...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.01.007

    authors： Frilling A,Giele H,Vrakas G,Reddy S,Macedo R,Al-Nahhas A,Wasan H,Clift AK,Gondolesi GE,Vianna RM,Friend P,Vaidya A

    更新日期：2015-04-01 00:00:00

  • Analysis of survival after primary liver transplantation: multivariate analysis of 155 cases in a single center.

    abstract：:Liver transplantation is known as a highly complex procedure. Several variables can affect the outcome. The present study is a retrospective multivariate analysis of the outcomes of primary liver transplant recipients from deceased donors. From November 2006 through January 2009, 155 patients received first liver tran...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2010.01.014

    authors： Wiederkehr JC,Igreja MR,Nogara MS,Gonçalves NL,Wiederkehr BA,Nascimento VB,Coelho IM,Locatelli FP

    更新日期：2010-03-01 00:00:00

  • Combined spinal-epidural anesthesia for renal transplantation.

    abstract：INTRODUCTION:A patient undergoing renal transplantation presents unique problems to the anesthetist, as almost every body system is affected. The combined spinal-epidural technique has become popular in lower abdominal surgeries because it offers the advantages of both spinal and epidural techniques. We review our expe...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.03.027

    authors： Bhosale G,Shah V

    更新日期：2008-05-01 00:00:00

  • Extracorporeal shock wave lithotripsy of impacted radiolucent stone at the right pyeloureteric junction and oral dissolution therapy in a patient with transplanted liver: a case report.

    abstract：:Extracorporeal shock wave lithotripsy (ESWL) is a safe, effective method to treat urinary lithiasis. The success rate in ESWL depends on stone location, size, number, and fragility as well as calceal anatomy and patency of the urinary tract. An association of calcineurin inhibitors and uric acid urolithiasis has been ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.09.042

    authors： Mokos I,Pasini J,Hrstić I,Stern-Padovan R,Cacic Z,Knezevic N

    更新日期：2007-12-01 00:00:00

  • Family Function in Pediatric Liver Transplant Recipients Residing In a Developing Country.

    abstract：BACKGROUND:Pediatric liver transplantation (LT) can affect recipients' family function; however, inconsistent results between studies exist, and data from developing nations are sparse. We aimed to evaluate family function and identify factors associated with suboptimal function in pediatric LT recipients. METHODS:A c...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2020.01.035

    authors： Butsriphum N,Getsuwan S,Prabpram W,Chuthapisith J,Tanpowpong P,Lertudomphonwanit C,Treepongkaruna S

    更新日期：2020-04-01 00:00:00

  • An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients.

    abstract：:Mycophenolate mofetil (MMF) is an immunosuppressant used for the prophylaxis of rejection in renal, pancreas, and liver transplantation. It inhibits the inducible isoform of the enzyme inosine-monophosphate dehydrogenase (IMPDH II) via its active metabolite mycophenolic acid (MPA). IMPDH II is necessary for de novo pu...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.09.070

    authors： Vannozzi F,Filipponi F,Di Paolo A,Danesi R,Urbani L,Bocci G,Catalano G,De Simone P,Mosca F,Del Tacca M

    更新日期：2004-11-01 00:00:00

  • Measurement and clinical significance of interleukin 28B in hepatitis C virus-infected liver transplant patients.

    abstract：:One-third of the liver transplantations are performed because of hepatitis C cirrhosis all over the world and also in Hungary. The recurrence rate is practically 100%, influencing graft and patient survivals; within 5 years cirrhosis develops again in 20% to 30% of cases. The therapy is pegylated interferon α-2a and α...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2012.07.101

    authors： Gerlei Z,Sárváry E,Lengyel G,Görög D,Fehérvári I,Nemes B,Kóbori L,Langer RM

    更新日期：2012-09-01 00:00:00

  • Reconstruction of the Outflow Tract in Cross-Auxiliary Double-Domino Donor Liver Transplantation.

    abstract：BACKGROUND:Auxiliary liver transplantation is accepted as an effective manner to expand the liver donor pool. A difficult surgical technical challenge of the procedure is hepatic vein reconstruction of the graft. METHODS:To resolve this problem, complex techniques are used to perform an innovative outflow tract recons...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2016.07.031

    authors： Qu W,Zhu ZJ,Wei L,Sun LY,Liu Y,Zeng ZG

    更新日期：2016-10-01 00:00:00

  • Does etiology of end-stage renal disease affect sleep quality in kidney transplant recipients?

    abstract：BACKGROUND:That hypertension (HTN) as a leading cause of end-stage renal disease (ESRD) is linked to sleep disorders in the general population can be the basis of a hypothesis that HTN may be a contributing factor to the poor quality of sleep in some kidney transplant recipients. This study was designed to investigate ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.03.011

    authors： Ameli J,Kachuee H,Assari S,Rasta VR,Khoddami-Vishte HR,Einollahi B,Lessan-Pezeshki M,Khedmat H

    更新日期：2007-05-01 00:00:00

  • Liver transplantation in Medellin, Colombia: initial experience.

    abstract：OBJECTIVE:The goal of this article is to present the experience of a new liver transplant team. MATERIALS AND METHODS:This review includes all patients who received a liver transplant between March 15, 2000 and March 15, 2003. RESULTS:We performed 87 transplantations on 84 patients; 39 were females and 45 were males ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.06.020

    authors： Gutiérrez J,Guzmán C,Correa G,Restrepo J,Sepúlveda E,Yepes N,Gutiérrez M,Gómez F,Duque E,Tobón R,Duque J,Velásquez A

    更新日期：2004-07-01 00:00:00

  • Nitric oxide-mediated effects on liver blood flow.

    abstract：:We investigated whether blockade of nitric oxide synthase by the arginine analog l- NAME could affect peripheral liver blood flow (PLBF) or hepatocyte integrity (serum ALT) in either a control series or in a series subjected to mild reduction of liver blood flow by temporary clamping of the hepatic artery (HA). Anesth...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.09.135

    authors： Gustafsson BI,Wallin M,Delbro DS,Friman S

    更新日期：2005-10-01 00:00:00

  • Assessing the Potential Impact of the Declaration of Istanbul 2008 on Internet Reporting of Human Organ Transplantation-Related Crimes Using Interrupted Time Series Analysis and Meta-Analysis Approaches.

    abstract：BACKGROUND:A severe shortage in donor organs is the major driver for organ transplantation-related crimes. The Declaration of Istanbul 2008 (DOI) was created to stop such crimes. We investigated the impact of DOI on Internet reporting of transplantation-related crimes. METHODS:We conducted Google Advanced Searches to ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.transproceed.2019.10.011

    authors： Islam MM,Webb B,Palais R,Kuddus RH

    更新日期：2020-01-01 00:00:00

  • Impact of HLA-DPB1 Matching on Outcome of Unrelated Transplant for Hematologic Malignant Diseases: A Systematic Review and Meta-analysis.

    abstract：OBJECTIVE:Human leukocyte antigen match is the most important donor factor affecting transplant outcome. The HLA-DPB1 mismatch on the clinical outcome of hematopoietic stem cell transplant (HSCT) is less clear. This study is the first meta-analysis to investigate the impact of HLA-DPB1 loci mismatch on clinical outcome...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.transproceed.2019.04.053

    authors： Wang Y,Xu S,Fang P

    更新日期：2019-01-01 00:00:00

  • The colon displays an absorptive capacity of tacrolimus.

    abstract：PURPOSE:In our previous study, blood levels of orally administered tacrolimus were significantly higher in short bowel piglets than in control animals. It has been reported that the blood levels of tacrolimus are influenced by the metabolic activity of intestinal CYP3A4. If tacrolimus may be absorbed in the colon, dire...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2003.12.013

    authors： Nishi K,Ishii T,Wada M,Amae S,Sano N,Nio M,Hayashi Y

    更新日期：2004-03-01 00:00:00

  • Updated status of deceased-donor liver graft allocation for high-urgency adult patients in a Korean high-volume liver transplantation center.

    abstract：BACKGROUND:The number of deceased organ donors in Korea has been gradually increased to reach 8 per million population. This study intended to analyze the updated status of urgent deceased-donor liver transplantation in a Korean high-volume liver transplantation center. METHODS:A retrospective study was performed with...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.02.014

    authors： Jung BH,Hwang S,Song GW,Jung DH,Ha TY,Park GC,Ahn CS,Moon DB,Kim KH,Kwang SH,Yoon YI,Shin MH,Kim WJ,Kang WH,Kim SH,Lim TW,Lee SG

    更新日期：2015-04-01 00:00:00

  • Evaluation of cortical bone by peripheral quantitative computed tomography in renal transplant recipients.

    abstract：BACKGROUND:The absolute risk of fractures in renal transplant patients is 3 times that of matched controls. Most of the symptomatic fractures are peripheral, suggesting a greater compromise of cortical bone. Peripheral quantitative computed tomography (pQCT) is a new imaging technique that allows separate noninvasive e...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.12.056

    authors： Negri AL,Lombas C,Cuevas C,Schiavelli R,Bogado CE,Zanchetta JR

    更新日期：2005-03-01 00:00:00

  • Use of catheters with the AgION antimicrobial system in kidney transplant recipients to reduce infection risk.

    abstract：:Microbial blood infection represents a high risk for immuno-suppressed patients. Of all catheter-related infections in the bloodstream, 90% result from the use of central venous catheters, the main cause being microbial colonization at the catheter's insertion point or the catheter hub. Between January 2003 and Decemb...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2006.01.064

    authors： Loertzer H,Soukup J,Hamza A,Wicht A,Rettkowski O,Koch E,Fornara P

    更新日期：2006-04-01 00:00:00

  • Hepatitis C and the incidence of diabetes mellitus after renal transplant: influence of new immunosuppression protocols.

    abstract：BACKGROUND:Hepatitis C has been associated with an increased incidence of diabetes mellitus (DM) following renal transplantation (RT). METHODS:Patients who underwent RT between 1985 and 2001 were excluded if they showed DM prior to RT, graft survival of less than 90 days, and unknown anti-HCV status (n=15). Two groups...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/s0041-1345(03)00611-0

    authors： Gentil MA,López M,González-Roncero F,Rodríguez-Algarra G,Pereira P,López R,Martínez M,Toro J,Mateos J

    更新日期：2003-08-01 00:00:00

  • Successful lung salvage by ex vivo reconditioning of neurogenic pulmonary edema: case report.

    abstract：:Liberalization in donor selection criteria allowed centers to increase the number of lung transplants, yet less than 25% of all donors had lungs utilized for transplantation in the United States in 2013. Less than 5% of all transplanted donors deviate 3 or more criteria from the ideal donor. Ex vivo lung perfusion (EV...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2014.06.062

    authors： Sanchez PG,Iacono AT,Rajagopal K,Griffith BP

    更新日期：2014-09-01 00:00:00

  • Donor bone-marrow suppressor of cytokine signaling-1-silenced dendritic cells prolong rat intestinal allograft survival.

    abstract：:Suppressor of cytokine signaling (SOCS) molecules belong to intracellular proteins that inhibit Janus kinase as well as signal transduction and activators of transcription pathways. In this study, we investigated whether SOCS-1-silenced dendritic cells (DCs) prolonged allograft survival in rat intestinal transplantati...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.07.131

    authors： Zhu C,Xu H,Zhang J,Wang K,Zhu P

    更新日期：2008-12-01 00:00:00

  • Epidemiologic and Economic Aspects Related to Hemodialysis and Kidney Transplantation in Santa Catarina in the Period of 2012-2013.

    abstract：BACKGROUND:Chronic kidney disease (CKD) is a worldwide public health problem and is expressed by increasing amounts of patients on renal replacement therapy (RRT), with significant economic and social impacts. The aim of this work was to analyze socioeconomic and mortality aspects of CKD patients in Santa Catarina (SC)...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2016.06.026

    authors： Silva AT,Soares LB,Magajewski FR

    更新日期：2016-09-01 00:00:00

  • Fetal listing for organ transplantation in Canada.

    abstract：:This article presents an ethical and legal examination of whether a fetus should be listed to receive a transplanted organ. To date, relatively little discussion of this question has found its way into either the clinical or ethics literature. This article is divided into four sections. The first section analyzes the ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2006.08.153

    authors： Russell BJ

    更新日期：2006-11-01 00:00:00

  • Contrast-enhanced ultrasonography in the early period after kidney transplantation predicts long-term allograft function.

    abstract：INTRODUCTION:Real-time contrast-enhanced sonography (CES) can assess microvascular tissue perfusion using gas-filled microbubbles. The purpose of the study was to evaluate the feasibility of early CES in predicting long-term kidney allograft function in comparison to color Doppler ultrasonography (CDUS). METHODS:We pr...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2014.04.013

    authors： Schwenger V,Hankel V,Seckinger J,Macher-Göppinger S,Morath C,Zeisbrich M,Zeier M,Kihm LP

    更新日期：2014-12-01 00:00:00

  • Peginterferon and ribavirin in patients with HCV cirrhosis after liver transplantation.

    abstract：:The objective of the study was to assess the efficacy of antiviral therapy in patients with hepatitis C virus (HCV) recurrence after liver transplantation (OLT). We included 30 patients of mean age 56 years, who experienced HCV recurrence after OLT. Mean time from OLT to the beginning of therapy was 57 months (median:...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.03.124

    authors： Moreno Planas JM,Rubio Gonzalez E,Boullosa Graña E,Garrido Botella A,Barrios Peinado C,Lucena Poza JL,Jiménez Garrido M,Sanchez Turrion V,Cuervas-Mons Martinez V

    更新日期：2005-06-01 00:00:00

  • HCV core protein augments cyclosporine immunosuppression.

    abstract：:Hepatitis C viremia occurs universally after liver transplantation. It is speculated that soluble HCV proteins may be immunomodulatory. We measured the effects of HCV core upon human T-cell proliferation, expression of activation markers, and interaction with cyclosporine. Cells were activated with anti-CD3 for 2-6 da...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.12.293

    authors： Kimball P,Verbeke S,Shiffman M

    更新日期：2005-03-01 00:00:00

  • Predicting the ideal serum creatinine of kidney transplant recipients by a simple formula based on the balance between metabolic demands of recipients and renal mass supply from donors.

    abstract：:Serum creatinine (Scr) is the most frequently used test to estimate graft function after kidney transplantation. Our previous study demonstrated that the independent predictors of recipient posttransplantation Scr included the ratio of graft weight to recipient body weight, the ratio of graft weight to recipient body ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.07.002

    authors： Oh CK,Lee BM,Kim H,Kim SI,Kim YS

    更新日期：2008-09-01 00:00:00