Calreticulin: conserved protein and diverse functions in plants.

Abstract:

:Calreticulin (CRT) is a key Ca2+-binding protein mainly resident in the endoplasmic reticulum (ER), which is highly conserved and extensively expressed in all eukaryotic organisms investigated. The protein plays important roles in a variety of cellular processes including Ca2+ signaling and protein folding. Although calreticulin has been well characterized in mammalian systems, increased investigations have demonstrated that plant CRTs have a number of specific properties different from their animal counterparts. Recent developments on plant CRTs have highlighted the significance of CRTs in plants growth and development as well as biotic and abiotic stress responses. There are at least two distinct groups of calreticulin isoforms in higher plants. Glycosylation of CRT was uniquely observed in plants. In this article, we will describe our current understanding of plant calreticulin gene family, protein structure, cellular localization, and diverse functions in plants. We also discuss the prospects of using this information for genetic improvements of crop plants.

journal_name

Physiol Plant

journal_title

Physiologia plantarum

authors

Jia XY,He LH,Jing RL,Li RZ

doi

10.1111/j.1399-3054.2009.1223.x

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

127-38

issue

2

eissn

0031-9317

issn

1399-3054

pii

PPL1223

journal_volume

136

pub_type

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