Management of childhood onset nephrotic syndrome.

Abstract:

:The therapeutic approach to childhood nephrotic syndrome is based on a series of studies that began with an international collaborative effort sponsored by the International Study of Kidney Disease in Children in 1967. The characteristics of children presenting with nephrotic syndrome have changed over recent decades with greater frequency of the challenging condition focal segmental glomerulosclerosis and a greater prevalence of obesity and diabetes mellitus, which may be resistant to glucocorticoids in the former and exacerbated by long-term glucocorticoid therapy in the latter 2 conditions. The Children's Nephrotic Syndrome Consensus Conference was formed to systematically review the published literature and generate a children's primary nephrotic syndrome guideline for use in educational, therapeutic, and research venues.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Gipson DS,Massengill SF,Yao L,Nagaraj S,Smoyer WE,Mahan JD,Wigfall D,Miles P,Powell L,Lin JJ,Trachtman H,Greenbaum LA

doi

10.1542/peds.2008-1559

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

747-57

issue

2

eissn

0031-4005

issn

1098-4275

pii

peds.2008-1559

journal_volume

124

pub_type

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