Population-based study of the incidence, complexity, and severity of neurologic disability among survivors weighing 500 through 1250 grams at birth: a comparison of two birth cohorts.

Abstract:

:Mortality and incidence, complexity, and severity of early childhood neurodevelopmental disability are reported for two cohorts of preterm infants of 500 through 1250 g birth weight. Comparing 1978-1979 (cohort 1) and 1988-1989 (cohort 2), 1-year survival improved from 82 (36%) of 226 to 197 (67%) of 291. Cohort 1 survivors were heavier and more mature than cohort 2 survivors (1047 g vs 930 g, 29.6 vs 27.3 weeks). Parental demographic variables were similar. The incidence of specific disabilities with greater than 97% follow-up to 1.5 years adjusted age did not change: cerebral palsy, 14 (17%) vs 20 (10%); vision loss, 5 (6%) vs 9 (5%); mental retardation, 9 (11%) vs 13 (7%); hearing loss, 3 (4%) vs 7 (4%); and convulsive disorders, 2 (2%) vs 3 (2%). The overall number of disabled children (17 [21%] vs 30 [15%]), complexity of disability (> or = 2 disabilities per child: 11 [13%] vs 10 [5%]), and severity of disability (projected dependency: 6 [7%] vs 10 [5%]) did not differ between cohorts 1 and 2. The cerebral palsy prevalence, based on neonatal survival, dropped from 157 per 1000 to 93 per 1000. Analysis by birth weight-specific categories in 250-g increments did not alter results, but disability rates were highest for those of lowest weight. In contrast to other reports this population-based North American study from a well-developed perinatal regional program reports no increase in incidence, complexity, or severity of disability in preterm infants weighing 500 through 1250 g at birth.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Robertson CM,Hrynchyshyn GJ,Etches PC,Pain KS

subject

Has Abstract

pub_date

1992-11-01 00:00:00

pages

750-5

issue

5

eissn

0031-4005

issn

1098-4275

journal_volume

90

pub_type

杂志文章
  • Clinical characteristics of peanut-allergic children: recent changes.

    abstract:OBJECTIVE:The goal was to determine whether patients seen in a referral clinic are experiencing initial allergic reactions to peanuts earlier, compared with a similar population profiled at a different medical center 10 years ago, and to investigate other changes in clinical characteristics of the patients between the ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-0350

    authors: Green TD,LaBelle VS,Steele PH,Kim EH,Lee LA,Mankad VS,Williams LW,Anstrom KJ,Burks AW

    更新日期:2007-12-01 00:00:00

  • Ethical Issues Raised by the Media Portrayal of Adolescent Transplant Refusals.

    abstract::Cases of adolescents in organ failure who refuse solid organ transplant are not common, but several have been discussed in the media in the United States and the United Kingdom. Using the framework developed by Buchanan and Brock for surrogate decision-making, I examine what role the adolescent should morally play whe...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-0818H

    authors: Ross LF

    更新日期:2020-08-01 00:00:00

  • Persistent beneficial effects of breast milk ingested in the neonatal intensive care unit on outcomes of extremely low birth weight infants at 30 months of age.

    abstract:BACKGROUND:We previously reported beneficial effects of breast milk ingestion by infants with extremely low birth weight in the NICU on developmental outcomes at 18 months' corrected age. The objective of this study was to determine whether these effects of breast milk in infants with extremely low birth weight persist...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2006-3227

    authors: Vohr BR,Poindexter BB,Dusick AM,McKinley LT,Higgins RD,Langer JC,Poole WK,National Institute of Child Health and Human Development National Research Network.

    更新日期:2007-10-01 00:00:00

  • Soothing pain-elicited distress in Chinese neonates.

    abstract:OBJECTIVE:To test the effect of nonnutritive sucking (NNS), music therapy (MT), and combined NNS and MT (NNS + MT), versus no intervention, on heart rate, transcutaneous oxygen (TcPaO(2)) levels, and pain behavior of neonates in intensive care units having blood taken by a heel-stick procedure. METHODOLOGY:A within-su...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1542/peds.105.4.e49

    authors: Bo LK,Callaghan P

    更新日期:2000-04-01 00:00:00

  • Gastrointestinal symptoms in children with type 1 diabetes screened for celiac disease.

    abstract:BACKGROUND:The association between celiac disease (CD) and type 1 diabetes mellitus (DM) is recognized. Most cases of CD in patients with DM are reported to be asymptomatic. OBJECTIVES:The objectives of this study were to (1) compare and audit our practice with the published standards for screening for CD in children ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-2434

    authors: Narula P,Porter L,Langton J,Rao V,Davies P,Cummins C,Kirk J,Barrett T,Protheroe S

    更新日期:2009-09-01 00:00:00

  • Screen Violence and Youth Behavior.

    abstract::Violence in screen entertainment media (ie, television, film, video games, and the Internet), defined as depictions of characters (or players) trying to physically harm other characters (or players), is ubiquitous. The Workgroup on Media Violence and Violent Video Games reviewed numerous meta-analyses and other releva...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2016-1758T

    authors: Anderson CA,Bushman BJ,Bartholow BD,Cantor J,Christakis D,Coyne SM,Donnerstein E,Brockmyer JF,Gentile DA,Green CS,Huesmann R,Hummer T,Krahé B,Strasburger VC,Warburton W,Wilson BJ,Ybarra M

    更新日期:2017-11-01 00:00:00

  • Prophylactic Early Erythropoietin for Neuroprotection in Preterm Infants: A Meta-analysis.

    abstract:CONTEXT:Recombinant human erythropoietin (rhEPO) is a promising pharmacological agent for neuroprotection in neonates. OBJECTIVE:To investigate whether prophylactic rhEPO administration in very preterm infants improves neurodevelopmental outcomes in a meta-analysis of randomized controlled trials (RCTs). DATA SOURCES...

    journal_title:Pediatrics

    pub_type: 杂志文章,meta分析,评审

    doi:10.1542/peds.2016-4317

    authors: Fischer HS,Reibel NJ,Bührer C,Dame C

    更新日期:2017-05-01 00:00:00

  • Disseminated fungal infections in very low-birth-weight infants: therapeutic toxicity.

    abstract::The improved survival of very low-birth-weight infants, who require prolonged hospitalization and many invasive procedures, increases the risks for nosocomial illnesses, such as disseminated fungal infections. In a 2-year period, systemic fungal infections were clinically diagnosed in ten infants. This necessitated th...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Baley JE,Kliegman RM,Fanaroff AA

    更新日期:1984-02-01 00:00:00

  • Smoking patterns among adolescents with asthma attending upper secondary schools: a community-based study.

    abstract:OBJECTIVE:Smoking among people who have asthma may be a serious health problem. We studied the prevalence of smoking and the relations between smoking and asthma, symptoms, medicine, and gender differences among adolescents with asthma. METHODS:A national cross-sectional study on health and lifestyles was performed in...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.111.5.e562

    authors: Precht DH,Keiding L,Madsen M

    更新日期:2003-05-01 00:00:00

  • Providing therapeutic services to children in special educational placements: an analysis of the related services provisions of Public Law 94-142 in five urban school districts.

    abstract::Using the sample of 1726 special education students from the Collaborative Study of Children With Special Needs, the authors describe the related services being provided to the children and then analyze the relationship between service provision and class placement. Related services are provided in all settings, with ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Palfrey JS,Singer JD,Raphael ES,Walker DK

    更新日期:1990-04-01 00:00:00

  • Echocardiographic evaluation of asymptomatic parental and sibling cardiovascular anomalies associated with congenital left ventricular outflow tract lesions.

    abstract:OBJECTIVE:Left ventricular outflow tract obstructive (LVOTO) malformations are a leading cause of infant mortality from birth defects. Genetic mechanisms are likely, and there may be a higher rate of asymptomatic LVOTO anomalies in relatives of affected children. This study sought to define the incidence of cardiac ano...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2003-0782-L

    authors: Lewin MB,McBride KL,Pignatelli R,Fernbach S,Combes A,Menesses A,Lam W,Bezold LI,Kaplan N,Towbin JA,Belmont JW

    更新日期:2004-09-01 00:00:00

  • Obesity and Mortality Risk in Critically Ill Children.

    abstract:BACKGROUND AND OBJECTIVES:Childhood obesity is epidemic and may be associated with PICU mortality. Using a large multicenter PICU database, we investigated the association between obesity and PICU mortality, adjusting for initial severity of illness. We further investigated whether height- and weight-based classificati...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2015-2035

    authors: Ross PA,Newth CJ,Leung D,Wetzel RC,Khemani RG

    更新日期:2016-03-01 00:00:00

  • Neurologic history and examination results and their relationship to human immunodeficiency virus type 1 serostatus in hemophilic subjects: results from the hemophilia growth and development study.

    abstract::In a prospective study of the growth and neuropsychologic function of hemophilic subjects, 333 boys, median age of 12.3 years, had baseline neurologic examinations. The study population included 207 individuals (62%) who were seropositive for human immunodeficiency virus type 1 (HIV-1). Overall results indicated that ...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Bale JF Jr,Contant CF,Garg B,Tilton A,Kaufman DM,Wasiewski W

    更新日期:1993-04-01 00:00:00

  • Association of apolipoprotein E genotype and cerebral palsy in children.

    abstract:OBJECTIVES:We tested the hypotheses that apolipoprotein E genotype, in particular carriage of the epsilon4 allele, is more likely to be associated with cerebral palsy and that children with more severe neurologic impairment are more likely to carry this allele. METHODS:In this cross-sectional study, 209 children with ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-1083

    authors: Kuroda MM,Weck ME,Sarwark JF,Hamidullah A,Wainwright MS

    更新日期:2007-02-01 00:00:00

  • Back to sleep: can we influence child care providers?

    abstract:OBJECTIVE:Despite the fact that 20% of sudden infant death syndrome (SIDS) deaths occur in child care settings, many child care providers continue to be unaware of the association of SIDS and infant sleep position and/or are misinformed as to the risks and benefits of the various sleep positions. The objective of this ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.112.4.878

    authors: Moon RY,Oden RP

    更新日期:2003-10-01 00:00:00

  • Revised guidelines for prevention of early-onset group B streptococcal (GBS) infection. American Academy of Pediatrics Committee on Infectious Diseases and Committee on Fetus and Newborn.

    abstract::In 1992, the Committee on Infectious Diseases and Committee on Fetus and Newborn of the American Academy of Pediatrics provided guidelines for prevention of early-onset group B streptococcal (GBS) disease through intrapartum chemoprophylaxis of selected maternal GBS carriers. The guidelines were based on demonstrated ...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章,实务指引

    doi:10.1542/peds.99.3.489

    authors:

    更新日期:1997-03-01 00:00:00

  • Transition to adulthood: the important role of the pediatrician.

    abstract::This article, written by a parent of 2 youths with special health care needs and a pediatrician, builds on the Medical Home framework to give concrete examples of what physicians and families can and should do to prepare families for transition(s). The article consists of 3 parts. The first part is an introduction giv...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.113.3.e159

    authors: Olsen DG,Swigonski NL

    更新日期:2004-03-01 00:00:00

  • Social factors associated with prolonged hospitalization among diabetic children.

    abstract:OBJECTIVE:To determine social factors associated with increased risk of hospital admission from diabetic ketoacidosis (DKA) or diabetic coma as well as risk of prolonged hospital stay. METHODS:A cohort of all children (

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.109.1.40

    authors: Keenan HT,Foster CM,Bratton SL

    更新日期:2002-01-01 00:00:00

  • Impact of the thimerosal controversy on hepatitis B vaccine coverage of infants born to women of unknown hepatitis B surface antigen status in Michigan.

    abstract:OBJECTIVE:Hepatitis B vaccine is recommended for all infants, and the series may be started during the delivery admission. For infants who are born either to women who are positive for hepatitis B surface antigen (HBsAg) or to women whose HBsAg status is unknown, vaccination should be started within 12 hours of birth t...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.111.6.e645

    authors: Biroscak BJ,Fiore AE,Fasano N,Fineis P,Collins MP,Stoltman G

    更新日期:2003-06-01 00:00:00

  • The mononuclear phagocyte system: role in expression of immunocompetence in neonatal and adult life.

    abstract::The cells of the mononuclear phagocyte system are critical elements in host defense. They are essential to many specific immune processes in addition to their well-recognized role in nonspecific resistance. In this report we describe studies of the influence of the maturation of this system of cells on the capacity of...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Blaese RM,Poplack DG,Muchmore AV

    更新日期:1979-11-01 00:00:00

  • The effects of multisystemic therapy on diabetes stress among adolescents with chronically poorly controlled type 1 diabetes: findings from a randomized, controlled trial.

    abstract:OBJECTIVE:The goal of this study was to determine whether multisystemic therapy (MST), an intensive, home-based psychotherapy, could decrease diabetes-related stress among adolescents with chronically poorly controlled type 1 diabetes. Stress was also evaluated as a mediator of the effect of MST on adherence and metabo...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2005-0638

    authors: Ellis DA,Frey MA,Naar-King S,Templin T,Cunningham PB,Cakan N

    更新日期:2005-12-01 00:00:00

  • Mental health problems and overweight in a nationally representative sample of adolescents: effects of race and ethnicity.

    abstract:OBJECTIVES:In this study we examined the relation between mental health problems and weight in a population-based study of youth aged 12 to 17 years and whether the association between mental health problems and weight is moderated by race and ethnicity. METHODS:We used 2003 National Survey on Children's Health data. ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-0687

    authors: BeLue R,Francis LA,Colaco B

    更新日期:2009-02-01 00:00:00

  • Mental Health Services Utilization and Expenditures Among Children Enrolled in Employer-Sponsored Health Plans.

    abstract:BACKGROUND AND OBJECTIVES:Mental illness in children increases the risk of developing mental health disorders in adulthood, and reduces physical and emotional well-being across the life course. The Mental Health Parity and Addiction Equity Act (MHPAEA, 2008) aimed to improve access to mental health treatment by requiri...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-2786G

    authors: Walter AW,Yuan Y,Cabral HJ

    更新日期:2017-05-01 00:00:00

  • Adult patient visits to children's hospital emergency departments.

    abstract:BACKGROUND:Adults frequently seek medical services in children's hospital emergency departments (CHEDs), and are required to be admitted to CHEDs under the provisions of the Emergency Medical Transfer and Active Labor Act (EMTALA), which requires medical evaluation and stabilization of every patient who presents to an ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.111.6.1268

    authors: Bourgeois FT,Shannon MW

    更新日期:2003-06-01 00:00:00

  • Children with special needs in England and Wales: the care of hearing impairment, myelomeningocele, and adolescent pregnancy.

    abstract::Services for children with special needs in England and Wales are described briefly, with attention to the services provided by the National Health Service, local authorities, the social security system, and voluntary organizations. For illustrative purposes, particular reference is made to children with hearing impai...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Goodwin S

    更新日期:1990-12-01 00:00:00

  • Adiposity and different types of screen time.

    abstract:OBJECTIVE:Few prospective studies have examined separate forms of screen time in relation to adiposity. Our objective was to assess independent relations of television, electronic games (video/computer), and digital versatile disc (DVD)/videos and total screen time with change in adolescent BMI. METHODS:Using data fro...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-0887

    authors: Falbe J,Rosner B,Willett WC,Sonneville KR,Hu FB,Field AE

    更新日期:2013-12-01 00:00:00

  • Conclusion: The Equity Project.

    abstract::As a result of the work completed during the meeting and summarized at the last session, 4 implementation groups have been established as the organizational framework for the American Academy of Pediatrics (AAP)-Royal College of Paediatrics and Child Health (RCPCH) Equity Project. This project will be the mechanism by...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Goldhagen J,Waterston T

    更新日期:2003-09-01 00:00:00

  • Nutrient and mineral retention and vitamin D absorption in low-birth-weight infants: effect of medium-chain triglycerides.

    abstract::A randomized prospective study of the effect of medium-chain triglycerides (MCT) upon the absorption and retention of major minerals and nutrients, as well as upon 25-hydroxy vitamin D levels, was performed in low-birth-weight infants. Ten infants received a high-calcium and vitamin D-containing formula, which contain...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Huston RK,Reynolds JW,Jensen C,Buist NR

    更新日期:1983-07-01 00:00:00

  • Parental Smoking Cessation: Impacting Children's Tobacco Smoke Exposure in the Home.

    abstract:OBJECTIVES:There is no safe or risk-free level of tobacco use or tobacco smoke exposure. In this randomized controlled trial, we tested a tobacco control intervention in families and specifically evaluated a tailored cessation intervention for the parents and/or caregivers (Ps/Cs) who were smokers while their children ...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2017-1026M

    authors: Caldwell AL,Tingen MS,Nguyen JT,Andrews JO,Heath J,Waller JL,Treiber FA

    更新日期:2018-01-01 00:00:00

  • Transition care for children with special health care needs.

    abstract:BACKGROUND:Approximately 750,000 children in the United States with special health care needs will transition from pediatric to adult care annually. Fewer than half receive adequate transition care. METHODS:We had conversations with key informants representing clinicians who provide transition care, pediatric and adul...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2014-1909

    authors: Davis AM,Brown RF,Taylor JL,Epstein RA,McPheeters ML

    更新日期:2014-11-01 00:00:00