Recent developments in siderotyping: procedure and application.

Abstract:

:Siderophores are metal chelating secondary metabolites secreted by almost all organisms. Beside iron starvation, the ability to produce siderophores depends upon several other factors. Chemical structure of siderophore is very complex with vast structural diversity, thus the principle challenge involves its detection, quantification, purification and characterisation. Metal chelation is its most fascinating attribute. This metal chelation property is now forming the basis of its application as molecular markers, siderotyping tool for taxonomic clarification, biosensors and bioremediation agents. This has led researchers to develop and continuously modify previous techniques in order to provide accurate and reproducible methods of studying siderophores. Knowledge obtained via computational approaches provides a new horizon in the field of siderophore biosynthetic gene clusters and their interaction with various proteins/peptides. This review illustrates various techniques, bioinformatics tools and databases employed in siderophores' studies, the principle of analytical methods and their recent applications.

authors

Singh P,Khan A,Kumar R,Kumar R,Singh VK,Srivastava A

doi

10.1007/s11274-020-02955-7

subject

Has Abstract

pub_date

2020-10-31 00:00:00

pages

178

issue

12

eissn

0959-3993

issn

1573-0972

pii

10.1007/s11274-020-02955-7

journal_volume

36

pub_type

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