Evaluation of an Assay for MGMT Gene Promoter Methylation in Glioblastoma Samples.

abstract：BACKGROUND:The standard treatment of epithelial ovarian cancer is tumor debulking by surgery, followed by six cycles of chemotherapy consisting of cisplatinum and paclitaxel. However, this therapy protocol is not satisfactory, since about 50% of the treated patients eventually experience recurrence within a few years o...

journal_title：Anticancer research

authors： Law KS,Chen HC,Liao SK

更新日期：2007-03-01 00:00:00

abstract：:Glucose consumption and tritiated thymidine incorporation were monitored for 54 days in histocultured human superficial transitional cell carcinoma of the bladder, indicating that long-term histoculture of human transitional cell carcinoma of the bladder is feasible. The glucose-consumption rate was relatively similar...

journal_title：Anticancer research

authors： Chang SG,Lee JH,Hong DH,Lee HL,Chai SE,Hoffman RM

更新日期：1994-01-01 00:00:00

abstract：:The Fiber Hypothesis which had its origins in the work of Burkitt and others in the early 1970's, focussed largely on fiber's beneficial effects on colon cancer and disorders of the gastric intestinal tract. In the 1980's it was proposed that fiber may also have beneficial effects on breast cancer and a rational for t...

journal_title：Anticancer research

authors： Cohen LA

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) directed against epidermal growth factor receptor (EGFR) are important in the treatment of non-small cell lung cancer (NSCLC), especially those harboring EGFR mutations. But little is known regarding the clinical value of serum tumor marker levels measured prior to treatment...

journal_title：Anticancer research

authors： Takeuchi A,Oguri T,Sone K,Ito K,Kitamura Y,Inoue Y,Asano T,Fukuda S,Kanemitsu Y,Takakuwa O,Ohkubo H,Takemura M,Maeno K,Ito Y,Niimi A

更新日期：2017-10-01 00:00:00

abstract：:The objective of the present study was to investigate the effect of dietary phytosterols on the growth and metastasis of the human breast cancer MDA-MB-231 cell line xenografted in SCID mice. Two groups of animals were fed AIN-93G diet supplemented with 0.2% cholic acid and 2% sterol (cholesterol or phytosterol mixtur...

journal_title：Anticancer research

authors： Awad AB,Downie A,Fink CS,Kim U

更新日期：2000-03-01 00:00:00

abstract：:Seventy natural and synthetic compounds were tested for potential to inhibit mutation induced by 7,12-dimethylbenz(a)anthracene (DMBA) in Salmonella typhimurium strain TM677. Results were compared with their ability to inhibit DMBA-induced preneoplastic lesions in a mouse mammary gland organ culture system. The respon...

journal_title：Anticancer research

authors： Shamon LA,Chen C,Mehta RG,Steele V,Moon RC,Pezzuto JM

更新日期：1994-09-01 00:00:00

abstract：UNLABELLED:The diagnostic accuracy of fused positron emission tomography/computed tomography (PET/CT) was compared with CT alone and PET alone in the staging and re-staging of nasopharyngeal carcinoma (NPC) patients. PATIENTS AND METHODS:Eighty-six fluorine-18-2-fluoro-2-deoxy-D-glucose (FDG) PET/CT studies were retro...

journal_title：Anticancer research

authors： Chen YK,Su CT,Ding HJ,Chi KH,Liang JA,Shen YY,Chen LK,Yeh CL,Liao AC,Kao CH

更新日期：2006-03-01 00:00:00

abstract：:We report application of a novel immunohistochemical procedure for the staining of apoptotic (AP) cells in paraffin sections using monoclonal antibody (MAb) to single-stranded DNA. MAb differentiated between apoptosis and necrosis and in contrast to in situ end labelling specifically stained only AP cells. AP carcinom...

journal_title：Anticancer research

authors： Frankfurt OS,Robb JA,Sugarbaker EV,Villa L

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:The aim of this work was to study the constituents and cytotoxicity of the essential oils from the fruits of Angelica archangelica growing in Iceland. MATERIALS AND METHODS:Three samples of essential oils were prepared by steam distillation. Their composition was established with GC/MS. The effects of the o...

journal_title：Anticancer research

authors： Sigurdsson S,Ogmundsdottir HM,Gudbjarnason S

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Studies have recommended a 21-gene recurrence score (RS) to optimize adjuvant treatment for patients with early-stage breast cancer (EBC) with hormone receptor-positive (HR+) and human epidermal growth factor receptor-2 negative (HER2-) tumors. This study aimed to prospectively evaluate the impact of this RS...

journal_title：Anticancer research

authors： Zeng Y,Li Q,Qin T,Li S,Jin L,Wu J,Chen K,Deng H,Rao N,Liu Q,Su F,Jia W,Yao H

更新日期：2017-08-01 00:00:00

abstract：:The content, composition and physicochemical characteristics of glycosaminoglycans in human rectum and rectum carcinoma were investigated by chemical analyses, enzymic treatments, chromatographic and electrophoretic techniques. The overall glycosaminoglycan content was increased about 2 fold in neoplastic tissues comp...

journal_title：Anticancer research

authors： Tsara ME,Papageorgacopoulou N,Karavias DD,Theocharis DA

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:The present study investigated the mechanism underlying the apoptosis of MKN28 human gastric cancer cells induced by the phosphatidylinositol (PI) derivative 1,2-O-bis-[8-{2-(2-pentyl-cyclopropylmethyl)-cyclopropyl}-octanoyl]-sn-glycero-3-phosphatidyl-D-1-inositol (diDCP-LA-D-PI) and its enantiomer diDCP-LA-...

journal_title：Anticancer research

authors： Ohyama M,Tsuchiya A,Kaku Y,Kanno T,Shimizu T,Tanaka A,Nishizaki T

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND/AIM:We investigated the effect of aspirin on colorectal cancer (CRC) risk among subgroups of women with and without risk factors for CRC. PATIENTS AND METHODS:Using data from the Women's Health Initiative, we estimated hazard ratios for CRC in association with aspirin use, with stratifications by cardiovasc...

journal_title：Anticancer research

authors： Seaton ME,Peters U,Johnson KC,Kooperberg C,Bafford A,Zubair N

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Epithelial protein lost in neoplasm-α (EPLIN-α) is a cytoskeletal protein whose expression is often lost or is aberrant in cancerous cells and tissues and whose loss is believed to be involved in aggressive phenotype. Our current study examined this molecule in human oesophageal tissues and investigated the ...

journal_title：Anticancer research

authors： Liu Y,Sanders AJ,Zhang L,Jiang WG

更新日期：2012-04-01 00:00:00

abstract：:The Feulgen-DNA content of squamous carcinoma cell nuclei from the human esophagus was assessed in punch biopsies from 47 untreated patients. Forty-four of the 47 biopsies (93.6%) demonstrated aneuploid cell populations, and the remaining 3 (6.4%) were non-diploid. Previous studies have demonstrated that in esophageal...

journal_title：Anticancer research

authors： Munck-Wikland E,Auer G,Kuylenstierna R,Lindholm J,Rubio C

更新日期：1989-05-01 00:00:00

abstract：:The effect on liver tissue of glutathione administration to rats treated for 7-14 days with 2-acetylaminofluorene was investigated. The DNA damage induced by the hepatotoxic agent and evaluated by the alkaline elution technique was significantly reduced by glutathione. Furthermore, GSH administration maintained liver ...

journal_title：Anticancer research

authors： Cesarone CF,Scarabelli L,Orunesu M

更新日期：1986-11-01 00:00:00

abstract：:We have established a practical system for generating antitumor effector lymphocytes using the tumor antigen peptide CEA and cultured dendritic cells (DCs), and have also characterized effector cells. DCs were induced from the adherent cell population of autologous peripheral blood mononuclear cells (PBMCs) obtained f...

journal_title：Anticancer research

authors： Ohta K,Yamaguchi Y,Shimizu K,Miyahara E,Toge T

更新日期：2002-09-01 00:00:00

abstract：:The relationship between apoptosis and chemosensitivity remains complex. We tested the chemosensitivity of 45 patients with advanced breast cancer (BC) ex vivo against anthracyclines (A: doxorubicin, epirubicin), taxanes (T: paclitaxel, docetaxel), cisplatin (DDP) and CMF and any correlation with the expression of p53...

journal_title：Anticancer research

authors： Rein DT,Schöndorf T,Breidenbach M,Janát MM,Weikelt A,Göhring UJ,Becker M,Mallmann P,Kurbacher CM

更新日期：2000-11-01 00:00:00

abstract：:A total of 2090 patients with endometrial carcinoma were followed-up for at least five years. The treatment modalities, as well as the results of treatment, regarding 272 patients with disease relapse are presented. The results are not encouraging. We found no statistically significant difference regarding overall sur...

journal_title：Anticancer research

authors： Lindahl B,Ranstam J,Willén R

更新日期：2012-08-01 00:00:00

abstract：:The incorporation and metabolism of delta-6-desaturase substrate and product, [1-14C]-linoleic (18:2n-6) and [1-14C]-gamma-linolenic acid (18:3n-6), was examined in NIH-3T3 cells and the DT subclone which differs only in the presence of the v-Ki-ras oncogene. Similar amounts of post delta-6 and delta-5 desaturase meta...

journal_title：Anticancer research

authors： De Antueno RJ,Cantrill RC,Ells GW,Elliot M,Huang YS,Horrobin DF

更新日期：1993-07-01 00:00:00

abstract：:Angiogenesis is critical for tumor growth and inflammation. Shiunko is a Chinese herbal ointment used for the treatment of burns in Japan. Its main ingredient is the root of Lithospermum erythrorhizon, which had been used for treating tumors and inflammation in China since the 5th century. We report here that shikonin...

journal_title：Anticancer research

authors： Hisa T,Kimura Y,Takada K,Suzuki F,Takigawa M

更新日期：1998-03-01 00:00:00

abstract：:The presence of steroid receptors in breast cancer is usually considered as a good indicator for responsiveness to antiestrogen treatment. However, not all estrogen-receptor (ER) positive tumors respond to tamoxifen, probably owing to the natural heterogeneity of breast cancer, which after tamoxifen treatment can resu...

journal_title：Anticancer research

authors： Coradini D,Biffi A,Pirronello E,Di Fronzo G

更新日期：1995-03-01 00:00:00

abstract：:Dedifferentiated liposarcoma (DDLS) is a malignant adipocytic tumor showing transition from an atypical lipomatous tumor (ALT)/well-differentiated liposarcoma (WDLS) to a non-lipogenic sarcoma of variable histological grades. We present the immunohistochemical, cytogenetic, and molecular cytogenetic findings of DDLS a...

journal_title：Anticancer research

authors： Nishio J,Iwasaki H,Nabeshima K,Naito M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIM:Anthracyclines, such as doxorubicin, though widely used in anticancer therapy, they are associated with cardiotoxic side-effects. The aim of this trial was to investigate long-term follow-up cardiotoxicity findings in patients treated with doxorubicin and concomitant metoprolol or enalapril 10 years earl...

journal_title：Anticancer research

authors： Georgakopoulos P,Kyriakidis M,Perpinia A,Karavidas A,Zimeras S,Mamalis N,Kouvela M,Charpidou A

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Resistance to multiple chemotherapeutic agents results from a variety of factors including a lack of apoptosis in tumor cells. To induce apoptosis in two types of tumor cells, RPMI-8226 and MG-63, a combination of chemotherapeutic agents and retroviral transduction of TRAIL was employed. MATERIALS AND METHO...

journal_title：Anticancer research

authors： Suzuki H,Hotta T,Koyama T,Komagata M,Imakiire A,Yanase N,Yoshimoto T,Mizuguchi J

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Pulmonary complications (PCs) after esophagectomy for patients with esophageal cancer have been correlated with prolonged hospital stays and in-hospital mortality. Previous studies have shown that minimally-invasive esophagectomy (MIE) is associated with a lower rate of PCs compared to conventional open surg...

journal_title：Anticancer research

authors： Kubo N,Ohira M,Yamashita Y,Sakurai K,Toyokawa T,Tanaka H,Muguruma K,Shibutani M,Yamazoe S,Kimura K,Nagahara H,Amano R,Ohtani H,Yashiro M,Maeda K,Hirakawa K

更新日期：2014-05-01 00:00:00

abstract：:While reserpine and nicardipine pretreatment induced a more or less marked decrease in typical red-orange doxorubicin fluorescence in certain rat tissues, such as spleen, kidney and large intestine, the myocardial tissue (right atrium and left ventriculum) did not show any significant variations in nuclear doxorubicin...

journal_title：Anticancer research

authors： Soldani P,Pellegrini A,Breschi MC,Natale G,Paparelli A

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND/AIM:Elderly patients with HPV+ oropharyngeal cancer (OPC) represent an understudied cohort of the HPV epidemic. We aimed to investigate the clinical presentation, treatment tolerability and outcomes in patient's ≥65 years old with HPV+ OPC. PATIENTS AND METHODS:We identified all patients aged 65 and older t...

journal_title：Anticancer research

authors： Dave E,Su W,Gupta V,Miles B,Demicco E,Soriano T,Bakst RL

更新日期：2017-04-01 00:00:00

abstract：:Ritonavir, a protease inhibitor, has been successfully applied in the treatment of HIV infection. Reports of dramatic improvement of AIDS-related cancers, such as primary central system lymphoma after radiation therapy as well as Kaposi's sarcoma, led to the recent discovery of the "non viral" antitumor activity of HI...

journal_title：Anticancer research

authors： Maggiorella L,Wen B,Frascogna V,Opolon P,Bourhis J,Deutsch E

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND/AIM:Combining an anticancer agent fenretinide (HPR) or C6-pyridinium ceramide (LCL29) with Foscan-mediated photodynamic therapy (FoscanPDT) is expected to augment anticancer benefits of each substance. We showed that treatment with FoscanPDT+HPR enhanced accumulation of C16-dihydroceramide, and that fumonisi...

journal_title：Anticancer research

authors： Boppana NB,Kraveka JM,Rahmaniyan M,Li LI,Bielawska A,Bielawski J,Pierce JS,Delor JS,Zhang K,Korbelik M,Separovic D

更新日期：2017-02-01 00:00:00