Studies on the activity of antithymocyte serum (ATS), particularly on the relation between its anti-inflammatory and immunosuppressive effects.

Abstract:

:Anti-inflammatory and immunosuppressive activity of equine antirabbit antithymocyte serum (ATS) was studied. ATS lowered serum levels of complement, inhibited cell proliferation in the granulation test, and prolonged survival of allogeneic skin grafts. Its action was accompanied by lymphopenia. Repeated immunization enhanced the activity of ATS in the graft rejection test and the drop in serum complement, and at the same time attenuated the effect on the granulation process and lowered proteolytic activity.

authors

Gieldanowski J,Blaszczyk B,Szymaniec S,Ludwikowska A

subject

Has Abstract

pub_date

1977-01-01 00:00:00

pages

367-75

issue

3

eissn

0004-069X

issn

1661-4917

journal_volume

25

pub_type

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