Memory CD8+ T cell differentiation.

abstract：:A high index of suspicion is essential in arriving at the correct diagnosis of Lambert-Eaton myasthenic syndrome (LEMS). LEMS should be considered in the differential in any patient who has proximal weakness, reduced or absent muscle stretch reflexes, and dry mouth. Weakness predominates in hip and shoulder muscles, b...

journal_title：Annals of the New York Academy of Sciences

authors： Sanders DB

更新日期：2003-09-01 00:00:00

abstract：:NAFTA and GATT have specified that we must base import decisions on sound scientific information. This includes the use of risk assessment procedures to justify excluding or restricting the international movement of either live animals or products from animals. Procedures and techniques have been described for calcula...

journal_title：Annals of the New York Academy of Sciences

authors： Metcalf HE,Blackwell JH,Acree JA

更新日期：1996-07-23 00:00:00

abstract：:Studies on host responses in sheep artificially infected with Theileria sp. (China) were discussed and summarized mainly on typical high fever periods, merozoits and schizoon observation, antibody response. ...

journal_title：Annals of the New York Academy of Sciences

authors： Wu JS,Yu JM,Wang ZL,Song CP,Yuan JF,Yao BA

更新日期：2006-10-01 00:00:00

abstract：:We and others have previously shown that heat-shock proteins (HSPs) are involved in protecting the brain from a variety of insults including stroke, epilepsy, and other related insults. While the mechanism of this protection has largely been thought to be due to their chaperone functions (i.e., preventing abnormal pro...

journal_title：Annals of the New York Academy of Sciences

authors： Yenari MA,Liu J,Zheng Z,Vexler ZS,Lee JE,Giffard RG

更新日期：2005-08-01 00:00:00

abstract：:Hyperactivity of the hypothalamo-pituitary-adrenal (HPA) axis is often observed in association with and even prior to the onset of major depression. It is presently unclear (1) which molecular and cellular processes contribute to hyperactivity of parvocellular hypothalamic neurons (key regulators of the HPA system) an...

journal_title：Annals of the New York Academy of Sciences

authors： Joëls M,Verkuyl JM,Van Riel E

更新日期：2003-12-01 00:00:00

abstract：:Bacterial, plasmid, and synthetic DNA containing unmethylated CpG dinucleotides in specific sequence contexts activate the vertebrate innate immune system. A pattern recognition receptor (PRR), toll-like receptor 9 (TLR9), recognizes CpG DNA and activates signaling cascade leading to the secretion of a number of cytok...

journal_title：Annals of the New York Academy of Sciences

authors： Agrawal S,Kandimalla ER

更新日期：2003-12-01 00:00:00

abstract：:Galanin is widely distributed in enteric nerves and nerve terminals throughout the gastrointestinal (GI) tract. Within the GI tract galanin is best known for its ability to alter smooth muscle contractility and regulate intestinal motility. However, recent studies also indicate that galanin can modulate epithelial ion...

journal_title：Annals of the New York Academy of Sciences

authors： Benya RV,Matkowskyj KA,Danilkovich A,Hecht G

更新日期：1998-12-21 00:00:00

abstract：:Radioactive contamination from the Chernobyl meltdown spread over 40% of Europe (including Austria, Finland, Sweden, Norway, Switzerland, Romania, Great Britain, Germany, Italy, France, Greece, Iceland, Slovenia) and wide territories in Asia (including Turkey, Georgia, Armenia, Emirates, China), northern Africa, and N...

journal_title：Annals of the New York Academy of Sciences

authors： Yablokov AV,Nesterenko VB

更新日期：2009-11-01 00:00:00

abstract：:The recent identification of tumor-associated antigens (TAA) and TAA-derived peptides presented by MHC molecules to T cells has provided the tools to design and test clinical vaccines for treating human malignancies, such as melanoma. While the most effective adjuvant for use in vaccine formulation remains unclear, au...

journal_title：Annals of the New York Academy of Sciences

authors： Zitvogel L,Couderc B,Mayordomo JI,Robbins PD,Lotze MT,Storkus WJ

更新日期：1996-10-31 00:00:00

abstract：:Adolescence and emerging adulthood form a critical time period for the achievement of optimal health and nutrition across all stages of the life course. We undertook a review of published literature and global data repositories for information on nutrition levels, trends, and patterns among young people aged 10-24 yea...

journal_title：Annals of the New York Academy of Sciences

authors： Akseer N,Al-Gashm S,Mehta S,Mokdad A,Bhutta ZA

更新日期：2017-04-01 00:00:00

abstract：:Results of therapeutic trials of transfer factor in a number of laboratories suggest clinical benefit and enhancement of immunological reactivity in patients with primary or secondary immunodeficiency diseases. Long term follow-up of 32 patients with the Wiskott-Aldrich syndrome suggested that transfer factor caused c...

journal_title：Annals of the New York Academy of Sciences

authors： Spitler LE

更新日期：1979-01-01 00:00:00

abstract：:Sarcopenia is the involuntary loss of skeletal muscle mass and strength that occurs with aging, resulting in physical frailty. One potential explanation for sarcopenia is the failure of muscle to regenerate after damage, some of which may be due to changes in the function of satellite cells. Recent studies have identi...

journal_title：Annals of the New York Academy of Sciences

authors： Machida S,Narusawa M

更新日期：2006-05-01 00:00:00

abstract：:To summarize (Fig. 10), the structural consequences of monocular deprivation include the following changes: the relay cells in the binocular segments of the deprived geniculate layers shrink and contain less of the possible neurotransmitter NAAG. These changes appear to be secondary to a loss of terminal synaptic arbo...

journal_title：Annals of the New York Academy of Sciences

authors： Tieman SB

更新日期：1991-01-01 00:00:00

abstract：:Five hybridoma cell lines secreting anti-PrP antibodies were established from the fusion between mouse myeloma Sp2/0 and spleen cells from mice immunized with recombinant Chinese Luxi yellow cattle (Bos taurus, Luxi) PrP (24-234) or recombinant Chinese small-tailed Han sheep PrP (94-227). According to their Western bl...

journal_title：Annals of the New York Academy of Sciences

authors： Wu X,Wang Z,Liu Y,Zhang Y,Chen Y,Zou Y

更新日期：2006-10-01 00:00:00

abstract：:Iddm4 is a dominant non-major histocompatibility complex (MHC) determinant of diabetes susceptibility in BBDR rats treated with poly I:C, plus depletion of regulatory T cells. In congenic MHC-identical normal WF rats, Iddm4(d) sensitively and specifically predicts induced diabetes. We report a new diabetes-susceptible...

journal_title：Annals of the New York Academy of Sciences

authors： Blankenhorn EP,Descipio C,Rodemich L,Cort L,Leif JH,Greiner DL,Mordes JP

更新日期：2007-04-01 00:00:00

abstract：:The comparative study of vertebrate brains is inherently dependent upon access to a sufficient number of species and specimens to perform meaningful comparisons. Although many studies rely on compiling published information, continued specimen collection, in addition to more extensive use of existing brain collections...

journal_title：Annals of the New York Academy of Sciences

authors： Iwaniuk AN

更新日期：2011-05-01 00:00:00

abstract：:The following on proton pump inhibitors (PPIs) and chemoprevention in relation to Barrett's esophagus includes commentaries on 48-h pH monitoring, pH-impedence, bile acid testing, dyspepsia, long/short segment Barrett's esophagus, nonerosive reflux disease (NERD), functional heartburn, dual-release delivery PPIs, imme...

journal_title：Annals of the New York Academy of Sciences

authors： Richter JE,Penagini R,Tenca A,Pohl D,Dvorak K,Goldman A,Savarino E,Zentilin P,Savarino V,Watson JT,Wong RK,Pace F,Casini V,Peura DA,Herzig SJ,Kamiya T,Pelosini I,Scarpignato C,Armstrong D,DeVault KR,Bechi P,Tadd

更新日期：2011-09-01 00:00:00

abstract：:About 1 of 10 women, particularly those older than 60 years of age, shows some degree of thyroid hormone deficiency. Thyroid diseases are generally characterized by perturbations of thyroid signaling homeostasis. The most common examples of thyroid diseases include hypothyroidism, hyperthyroidism, and several types of...

journal_title：Annals of the New York Academy of Sciences

authors： Pistollato F,Masias M,Agudo P,Giampieri F,Battino M

更新日期：2019-05-01 00:00:00

abstract：:Female mosquitoes gorge on vertebrate blood, a rich nutrient source for developing eggs, but gorging meals increase the risk of predation. Mosquitoes are quick to reduce the flight payload with a potent diuresis. Diuretic peptides of the insect kinin family induce a tenfold reduction in the paracellular resistance of ...

journal_title：Annals of the New York Academy of Sciences

authors： Beyenbach KW

更新日期：2012-07-01 00:00:00

abstract：:Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) frequently develop and progress in settings in which sympathoadrenomedullary and gonadal hormone levels are changing, e.g., during pregnancy, postpartum period, menopause, estrogen administration. This paper addresses the view that adrenal and gonadal ho...

journal_title：Annals of the New York Academy of Sciences

authors： Wilder RL,Elenkov IJ

更新日期：1999-06-22 00:00:00

abstract：:We present our achievements in the synthesis and application of multifunctionalized, cross-linked, polystyrene microspheres, which remarkably and quite generally are taken up by all cell types studied to date. Importantly, the nature of these synthetic beads allows multistep solid-phase chemistry and the ability to bi...

journal_title：Annals of the New York Academy of Sciences

authors： Sánchez-Martín RM,Alexander L,Bradley M

更新日期：2008-01-01 00:00:00

abstract：:Information from the vestibular nuclei ascending through the brainstem to the oculomotor and trochlear nuclei (NIII, NIV), the interstitial nucleus of Cajal (INC), the pretectum, or thalamus, is thought to be distributed in at least five different pathways. They include the medial longitudinal fasciculus (MLF), the as...

journal_title：Annals of the New York Academy of Sciences

authors： Zwergal A,Strupp M,Brandt T,Büttner-Ennever JA

更新日期：2009-05-01 00:00:00

abstract：:Gene therapy as an immunomodulatory approach has the potential to treat various inherited and acquired immune-based human diseases. However, its clinical application has several challenges, varying from the efficiency of gene transfer, control of gene expression, cell and tissue targeting, and safety concerns associat...

journal_title：Annals of the New York Academy of Sciences

authors： Singh NP,Yolcu ES,Askenasy N,Shirwan H

更新日期：2005-11-01 00:00:00

abstract：:I2-imidazoline receptors (I2-IR) are characterized by their high affinity for imidazolines and guanidines and medium affinity for imidazolidines. The differential recognition of I2-IR by amiloride led to subtype these sites as amiloride-sensitive (I2A-IR) and amiloride-insensitive (I2B-IR). I2-IR labeled with [3H]idaz...

journal_title：Annals of the New York Academy of Sciences

authors： Olmos G,Alemany R,Boronat MA,García-Sevilla JA

更新日期：1999-06-21 00:00:00

abstract：:The success of embryonic implantation relies on an ideal cross-talk between the embryo and the receptive endometrium. This article focuses on the role of leukemia inhibitory factor (LIF) and its receptors in human embryo implantation. LIF is a secreted glycoprotein first described as a factor that induced the differen...

journal_title：Annals of the New York Academy of Sciences

authors： Aghajanova L

更新日期：2004-12-01 00:00:00

abstract：:Apolipoprotein E is a plasma cholesterol and phospholipid transporter which plays a central role in lipoprotein metabolism in the brain. Apolipoprotein E is a polymorphic protein with three common alleles in the general population, designated epsilon 2, epsilon 3 and epsilon 4 coding for proteins ApoE2, ApoE3 and ApoE...

journal_title：Annals of the New York Academy of Sciences

authors： Beffert U,Poirier J

更新日期：1996-01-17 00:00:00

abstract：:Adaptive co-evolution of mammals and bacteria has led to the establishment of complex commensal communities on mucosal surfaces. In spite of having available a wealth of immune-sensing and effector mechanisms capable of triggering inflammation in response to microbial intrusion, mucosal immune cells establish an intim...

journal_title：Annals of the New York Academy of Sciences

authors： Cerutti A,Cols M,Gentile M,Cassis L,Barra CM,He B,Puga I,Chen K

更新日期：2011-11-01 00:00:00

abstract：:This paper summarizes the goals of this section and considers current knowledge about the association between hormonal changes that occur over pubertal development and the changes in behavior and brain function over the adolescent period. It reviews the cascade of neural and hormonal changes that occur with puberty; d...

journal_title：Annals of the New York Academy of Sciences

authors： Cameron JL

更新日期：2004-06-01 00:00:00

abstract：:Statistical learning is a set of cognitive mechanisms allowing for extracting regularities from the environment and segmenting continuous sensory input into discrete units. The current study used functional magnetic resonance imaging (fMRI) (N = 25) in conjunction with an artificial language learning paradigm to provi...

journal_title：Annals of the New York Academy of Sciences

authors： Ordin M,Polyanskaya L,Soto D

更新日期：2020-05-01 00:00:00

abstract：:We have previously identified 30 differentially expressed genes when comparing recently diagnosed type 1 diabetes mellitus (DM-1) patients and controls paired for sex, age, and ethnic background. In this article we performed the hierarchical clustering of these genes taking into account the human-leukocyte-antigen (HL...

journal_title：Annals of the New York Academy of Sciences

authors： Rassi DM,Junta CM,Fachin AL,Sandrin-Garcia P,Mello SS,Fernandes AP,Deghaide NN,Foss-Freitas MC,Foss MC,Sakamoto-Hojo ET,Passos GA,Donadi EA

更新日期：2006-10-01 00:00:00