Abstract：
BACKGROUND:There is no universal management protocol concerning invasive malignant tumors of the scalp with bone and dura mater invasion. The aims of this study were to report and discuss our experience in the management of these forms of tumors. METHODS:We retrospectively reviewed all consecutive patients of microsurgical scalp reconstruction performed after resection of invasive cutaneous malignancies of the scalp, calvarium, and dura mater from 2017 to 2019, at Pitié-Salpêtrière University Hospital (Paris, France). RESULTS:Five patients met inclusion criteria. There were three squamous cell carcinomas and two sarcomas. Mean age at surgery was 63.6 years. The sex ratio male/female was 4. Two received radiation prior to resection and two patients had a history of prior scalp tumor surgery. All the patients underwent craniectomy and the mean cranial defect size was 41 cm2. Cranioplasty was performed in one patient. Soft tissue coverage was provided by free tissue transfer of latissimus dorsi muscle in all patients. In four patients, split thickness skin graft was performed in a second surgical stage few weeks later. There were no intraoperative complications and no complications into the donor site for the tissue transfer or the skin graft. Two patients had flap necrosis that healed after a new free flap of latissimus dorsi. CONCLUSIONS:Wide resection with craniectomy and reconstruction with microvascular free tissue transfer provides safe and reliable treatment of recalcitrant invasive scalp skin cancers. The surgical management of these complex patients is a challenge that must be conducted by trained, experienced, and multidisciplinary teams.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Marijon P,Bertolus C,Foy JP,Marechal G,Caruhel JB,Benassarou M,Carpentier A,Degos V,Amelot A,Mathon Bdoi
10.1007/s00701-020-04525-0subject
Has Abstractpub_date
2020-12-01 00:00:00pages
2991-2999issue
12eissn
0001-6268issn
0942-0940pii
10.1007/s00701-020-04525-0journal_volume
162pub_type
杂志文章abstract：BACKGROUND:Subarachnoid hemorrhage (SAH) has been recognized as a risk factor for ventriculostomy-related infections (VRI). In addition to the hemorrhagic cerebrospinal fluid (CSF), the potential need for prolonged catheterization may contribute to the increased CSF infection rate in this population. The use of antibio...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-012-1276-6
更新日期：2012-04-01 00:00:00
abstract：:We present a patient with an intracerebral haematoma occurring at a remote site following evacuation of a chronic subdural haematoma. Recurrence of the haematoma, infection, seizure, cerebral edema, tension pneumocephalus and failure of the brain to expand due to cerebro-cranial disproportion are the major complicatio...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-008-1512-2
更新日期：2008-05-01 00:00:00
abstract：BACKGROUND:Deep brain stimulation (DBS) is an effective treatment for essential tremor (ET). Currently the ventrolateral thalamus is the target of choice, but the posterior subthalamic area (PSA), including the caudal zona incerta (cZi), has demonstrated promising results, and the subthalamic nucleus (STN) has been sug...
journal_title：Acta neurochirurgica
pub_type： 临床试验,杂志文章
doi：10.1007/s00701-011-1157-4
更新日期：2011-12-01 00:00:00
abstract：:We describe a case of transsphenoidal deflation of a detachable balloon after embolization of a carotid-cavernous fistula (CCF). The patient developed complete third and sixth nerve palsies immediately after detachable balloon embolization of the CCF, which was considered to be caused by cavernous sinus (CS) compressi...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-006-1072-2
更新日期：2007-02-01 00:00:00
abstract：:Fifty-one cases of posterior fossa haemangioblastoma have been seen in our department over a period of 23 years. Seven cases were associated with spinal cord lesions and one with a supratentorial lesion. There were 22 cases of Lindau's disease (43%). The onset was earlier and recurrences commoner than in isolated case...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF02112026
更新日期：1993-01-01 00:00:00
abstract：:A medullary cone metastasis from an adenocarcinoma of esophagus, and a solitary lumbar spinal nerve root metastasis from a breast carcinoma, gave rise to two cases of cauda equina syndrome. Muscle strength in the lower limbs improved postoperatively, while the disturbances of bladder, bowel, and pelvic floor function ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01400978
更新日期：1981-01-01 00:00:00
abstract：INTRODUCTION:Melanotic neuroectodermal tumor of infancy (MNT1) is a rare congenital pigmented neoplasm of neural crest origin, locally aggressive, and rapidly growing that develops during the first year of life. It most commonly arises from the maxilla, the cranial vault, and the mandible. Early diagnosis and radical s...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,随机对照试验,评审
doi：10.1007/s00701-009-0472-5
更新日期：2010-05-01 00:00:00
abstract：:Cerebral primitive neuro-ectodermal tumour (PNET) occurring as a second primary malignancy in childhood is exceedingly rare. We present a 7-year-old boy who developed a proven supratentorial PNET five years after enucleation and radio-/chemotherapy for a sporadic, unilateral retinoblastoma with optic nerve invasion. T...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01420048
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:For gliomas, the goal of surgery is to maximise the extent of resection (EOR) while minimising the postoperative morbidity. The purpose of this study was to evaluate the benefits of a protocol developed for the surgical management of gliomas located in language areas, where tractography-integrated navigation...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-012-1580-1
更新日期：2013-03-01 00:00:00
abstract：:Clinical presentation, diagnosis, surgical technique and results of 25 cases of intramedullary tumours in patients under 16 years of age are analyzed. Pre-operative spinal deformity was present in 9 patients. Surgery was performed in all. After multilaminectomy with preservation of the intervertebral joints, total rem...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF02001471
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Many anatomical anomalies have the potential to impair the efficacy of endoscopic third ventriculostomy (ETV) and increase the surgical morbidity. By virtual magnetic resonance imaging (MRI) endoscopy, the real endoscopic view into the ventricular system can be simulated. It was the objective of the present ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s007010100000
更新日期：2001-11-01 00:00:00
abstract：BACKGROUND:Microvascular decompression (MVD) for hemifacial spasm (HFS) has been popular, but it may take enough time to master this special operative technique and procedure. This may induce uneven distribution of the number of MVD operations in each institute, possibly resulting in an overall unsatisfactory quality o...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-013-1724-y
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:The aim of this work was to retrospectively study the long-term reliability of the common consensus endocrinological criteria for the assessment of postoperative remission of acromegaly. PATIENTS AND METHODS:In 96 consecutive patients, surgical remission of acromegaly following transsphenoidal surgery was co...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-010-0790-7
更新日期：2011-01-01 00:00:00
abstract：OBJECTIVE:Distal middle cerebral artery (dMCA) aneurysms are very rare with a reported frequency of 2-6%. Typically, patients with ruptured distal MCA aneurysms have poor clinical outcomes because often there is both a subarachnoid haemorrhage (SAH) and an intracerebral haematoma (ICH). The goals of this study were to ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-007-1061-5
更新日期：2007-01-01 00:00:00
abstract：:The authors report a series of 37 cases of unruptured aneurysms, admitted and operated upon over a 5 year period (1985-1990), which represents an incidence of 18% of the total number of aneurysm patients operated upon during this period. These unruptured aneurysms were discovered in 4 types of circumstances: 1) Associ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01541779
更新日期：1992-01-01 00:00:00
abstract：BACKGROUND:Spinal epidural arachnoid cysts (EAC) are rare and may present with myelopathy, which can be completely curable with surgery. The majority of investigators believe that the repairment of dural defect is important to treat EAC. However, the necessity of excising EACs remains controversial. The purpose of this...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,评审
doi：10.1007/s00701-012-1356-7
更新日期：2012-07-01 00:00:00
abstract：:Vascular endothelium synthesizes mediators which either cause vasorelaxation or vasoconstriction. The purpose of this study is to investigate the role of these mediators in the pathogenesis of cerebral vasospasm. An inhibitor of endothelium-derived relaxing factor is haemoglobin; endothelium removal by triton X-100 an...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01401136
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:We developed a new simple therapeutic method for the treatment of chronic subdural hematoma (CSDH) without irrigation and drainage. This method is characterized by replacement of the hematoma with oxygen. METHODS:Seventy patients (seventy-eight sides) with CSDH were treated with this method from May 1994 to...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-005-0689-x
更新日期：2006-05-01 00:00:00
abstract：:Cell-mediated cytotoxicity (CTX) of meningioma patients towards meningioma cells and fibroblasts was studied in vitro before and after surgery, using the 3H-proline microcytotoxicity test. When incubated with allogeneic target cells before surgery, lymphocytes from three out of seven donors showed a specific destructi...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01808518
更新日期：1979-01-01 00:00:00
abstract：:First described on pre-B leukemia cells, the common acute lymphoblastic leukemia antigen (cALLa) is also expressed on glioma cells in vitro. Its identity to neutral endopeptidase (NEP) (E.C.3.24.11) was corroborated by our finding that cALLa positive glioma cells had NEP activity. To study cALLa/NEP distribution on gl...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01401105
更新日期：1992-01-01 00:00:00
abstract：:In 15 patients without acute brain injury the concentrations of Neuron-specific Enolase (NSE), S-100 Protein (S-100), Creatine Kinase (CK), and Creatine Kinase BB isoenzyme (CK-BB) in ventricular cerebrospinal fluid (CSF) were measured immediately after lateral ventricle cannulation for diagnostic or treatment purpose...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01400675
更新日期：1991-01-01 00:00:00
abstract：:Coil migration following cerebral aneurysm treatment has been described and may result in stroke, recurrent aneurysm, or local mass effect. Cerebral coil embolization is also applied in arteriovenous malformations and arteriovenous fistulas, but these pathologies are relatively rare and coil migration is not as well d...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-018-3689-3
更新日期：2018-12-01 00:00:00
abstract：:A rare case of primary cerebral abscess due to Nocardia asteroides, and its surgical removal, are described. Postoperative meningitis caused by the same fungi was succesfully cured with sulphadiazine and cycloserine. The nocardial disease, its neurological complications, and therapy are reviewed. ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01401932
更新日期：1977-01-01 00:00:00
abstract：BACKGROUND:An intracranial in situ side to side posterior circulation procedure is performed infrequently. The scope of treatment modalities of vertebral artery-PICA aneurysms and vertebral dissections is limited due to the lack of many representations of this procedure's technical nuances. METHODS:To demonstrate the ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-013-1874-y
更新日期：2013-11-01 00:00:00
abstract：INTRODUCTION:Spontaneous posterior interosseous nerve palsy is a rare condition. Entrapment is mostly at level of the arcade of Frohse, and a few cases of distal entrapment have been described. METHODS:A case of entrapment distal to the arcade of Frohse is described here. Cases of distal entrapment have been reviewed ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,评审
doi：10.1007/s00701-018-3615-8
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:To present the combined treatment of fusiform basilar artery aneurysms consisting of a surgical posterior fossa decompressive craniectomy and ventriculoperitoneal (VP) shunt operation at the same sitting, before the endovascular procedure with telescopic stenting of the aneurysmatic vessel segment in four ca...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-013-1913-8
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To study an effective method for surgical management of vertebral and basilar artery aneurysms. METHODS:Forty-one patients with 43 aneurysms of the vertebral and basilar arteries were managed by microsurgical clipping. Cerebral angiography revealed basilar apex aneurysms in 17 patients, basilar trunk in six ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-013-1656-6
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND:The resection of convexity meningiomas should harbour a low rate of morbidity. Functional preservation should be the main goal of surgery and have higher priority over radicality. Involvement of the primary motor cortex (PMC) increases surgical risk. The goal of this study was to evaluate the effect of corti...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-012-1279-3
更新日期：2012-05-01 00:00:00
abstract：BACKGROUND:Most complications of radiosurgery occur after 6-12 months and some long term complications up to after 5-10 years. Although severe, immediate side effects are rare, we report a patient who shows that this possibility should be taken into account when large volumes are treated especially in the posterior fos...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-003-0053-y
更新日期：2003-08-01 00:00:00
abstract：:We studied the influence of the type of surgery (microsurgery or macrosurgery) and extent (complete resection with lobectomy, complete resection alone, partial resection with lobectomy or partial resection alone) on early postoperative results and survival time in 118 consecutive patients who underwent surgery for gli...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01402111
更新日期：1991-01-01 00:00:00
