Muscle oxygen saturation measured using "cyclic NIR signals" during exercise.

Abstract:

:A new approach to measure muscle oxygen saturation (SmO(2)) using near infrared spectroscopy (NIRS) has been proposed in this paper. This approach exploits the cyclic NIRS signals seen during exercise which are often regarded as "movement artefacts". This new measure, which we term the "cyclic SmO(2)", has the potential to be less affected by the myoglobin which is traditionally believed to be indistinguishable from haemoglobin using NIRS techniques. The cyclic SmO(2) also has fewer assumptions than the conventional SmO(2) measured using time, phase and spatially resolved spectroscopy methods. In a cycling exercise study, NIRS measurements were made over the Vastus lateralis muscle of 11 subjects. In a light exercise protocol, the group mean of the conventional SmO(2) was 51.7 +/- 4.3% and that of the cyclic SmO(2) was 56.0 +/- 3.9%. It was immediately followed by a hard exercise protocol and the group mean of the conventional SmO(2) was reduced to 42.6 +/- 6.1% and that of the cyclic SmO(2) to 48.5 +/- 5.6%. The reduction agrees with the general expectation. The cyclic SmO(2) is a promising new measure of muscle oxygenation.

journal_name

Adv Exp Med Biol

authors

Leung TS,Wittekind A,Binzoni T,Beneke R,Cooper CE,Elwell CE

doi

10.1007/978-1-4419-1241-1_26

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

183-9

eissn

0065-2598

issn

2214-8019

journal_volume

662

pub_type

临床试验,杂志文章
  • Minimizing process induced prooxidant stresses.

    abstract::The adverse effects of trace metals, heat, steam and other conditions encountered in food processing relate to the acceleration of development of rancidity. Measures to retard oxidation of lipids, vitamins, pigments and proteins include elimination of prooxidants, removal of oxygen and use of blends of inhibitors form...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4899-1925-0_16

    authors: Evans RJ,Jones TS

    更新日期:1998-01-01 00:00:00

  • Mechanisms of active intestinal inflammation and potential down-regulation via lipoxins.

    abstract::Chronic inflammatory diseases of the intestine (i.e. Crohn's and chronic ulcerative colitis- collectively known as inflammatory bowel disease [IBD]) are a very significant public health problem in the United States and other industrialized nations. Thus, effort has been made toward understanding the biological mechani...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4615-0193-0_35

    authors: Gewirtz AT,Neish AS,Madara JL

    更新日期:2002-01-01 00:00:00

  • Calcium absorption in the rat colon measured in vivo.

    abstract::Calcium absorption in the large intestine was studied under physiological conditions in the rat. When 45Ca was administered directly into the caecum, the isotope was significantly absorbed. This absorption was modulated by dietary Ca and Pi as well as by the 1,25(OH) D3 status. On the other hand, calcium coming from t...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-5206-8_29

    authors: Ammann P,Rizzoli R,Fleisch H

    更新日期:1986-01-01 00:00:00

  • Relationship between microsomal hydroxylase and glucuronyltransferase.

    abstract::These experiments did not answer the question of whether one or several UDG-glucuronyltransferases are present in endoplasmic membranes of the liver. However, they present results which indicate that the glucuronlytransferase (s) have several properties in common with the hydroxylating cytochrome P-450 dependent enzym...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-9026-2_23

    authors: Remmer H,Bock KW,Rexer B

    更新日期:1975-01-01 00:00:00

  • Receptor-stimulated system mediated interactions of neuropeptides in GH3 cells.

    abstract::The interaction between two neuropeptides, VIP and TRH, was studied. The TRH receptor binding ability was examined using intact GH3 cells and its membrane fraction. The TRH binding ability decreased when intact cells were preincubated with VIP, forskolin or db-cAMP, but not when the membrane fraction was treated with ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4757-5971-6_10

    authors: Ogawa N,Haba K,Hirakawa S,Mizukawa K,Tsushima T

    更新日期:1988-01-01 00:00:00

  • Long-term expression of the human beta-globin gene after retroviral transfer into pluripotent hematopoietic stem cells of the mouse.

    abstract::We have studied the regulation of the human beta-globin gene after retroviral transfer into a variety of transformed and normal hematopoietic cells. After transfer into murine erythroleukemia cells (MEL) expression from the human beta-globin gene responds to inducers of erythroid maturation in parallel to the endogeno...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4613-0623-8_15

    authors: Gelinas RE,Bender MA,Miller AD,Novak U

    更新日期:1989-01-01 00:00:00

  • Impact of Ultraviolet Light on Vitiligo.

    abstract::Vitiligo is a disorder of the melanocytes that results in a dynamic spectrum of skin depigmentation. Its etiology is complex and multifactorial, with data supporting several different hypotheses. Given its prominent phenotype, vitiligo has a significant negative impact on quality of life. Coupled with the chronic and ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-56017-5_5

    authors: Singh RK

    更新日期:2017-01-01 00:00:00

  • Ovarian carcinogenesis: an alternative hypothesis.

    abstract::Observations indicate three different tissues of origin for ovarian carcinoma. The ovarian surface epithelium, oviduct epithelium (TSE), and derivates of the Müllerian duct. This chapter discusses the TSE-related ovarian carcinogenesis (exfoliation theory). Recent evidence from prophylactic removed ovaries and Fallopi...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-0-387-68969-2_7

    authors: Piek JM,van Diest PJ,Verheijen RH

    更新日期:2008-01-01 00:00:00

  • Ability of Three Lactic Acid Bacteria to Grow in Sessile Mode and to Inhibit Biofilm Formation of Pathogenic Bacteria.

    abstract::In this study, we explored the effect of three lactic acid bacteria (LAB), i.e. Enterococcus sp CM9, Enterococcus sp CM18 and Enterococcus faecium H3, and their supernatants, on seven biofilm-forming pathogenic strains isolated from human urinary tract or nose infections. By quantitative biofilm production assay, a st...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/5584_2020_495

    authors: Benmouna Z,Dalache F,Zadi-Karam H,Karam NE,Vuotto C

    更新日期:2020-01-01 00:00:00

  • Purification of angiotensin-converting enzyme from human intestine.

    abstract::Angiotensin-converting enzyme (ACE) activity in the intestinal whole homogenate was showed as three peaks on a column of Sephacryl S-300 HR gel filteration. Over 90% of total ACE activity was found in a soluble fraction separated with an ultracentrifuge of the intestinal homogenate, and the ACE activities were detecte...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-9546-5_60

    authors: Hayakari M,Amano K,Izumi H,Murakami S

    更新日期:1989-01-01 00:00:00

  • Effect of severely alkali-treated casein on gastrointestinal transit and selected intestinal enzyme activities.

    abstract::Alkaline treatment of proteins leads to chemical changes which alter the proteins' digestibility. Severely alkali-treated casein (0.2N NaOH, 80 degrees C, 1 hour) in the diet reduces food intake and growth of young but not of adult Sprague Dawley rats. Gastrointestinal transit time is not reduced significantly in eith...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4757-0022-0_30

    authors: Possompes B,Berger J

    更新日期:1986-01-01 00:00:00

  • Structure and evolution of tropomyosin genes.

    abstract::Tropomyosins constitute a family of highly related actin-binding proteins found in the animal kingdom from yeast to human. In vertebrates, they are encoded by a multigene family where each member can produce several isoforms through alternative splicing and for some of them with alternate promoters. Tropomyosin isofor...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-0-387-85766-4_2

    authors: Vrhovski B,Thézé N,Thiébaud P

    更新日期:2008-01-01 00:00:00

  • Hypoxia differentially regulates the mitogen- and stress-activated protein kinases. Role of Ca2+/CaM in the activation of MAPK and p38 gamma.

    abstract::Hypoxic/ischemic trauma is a primary factor in the pathology of various vascular, pulmonary, and cerebral disease states. Yet, the signaling mechanisms by which cells respond and adapt to changes in oxygen levels are not clearly established. The effects of hypoxia on the stress- and mitogen-activated protein kinase (S...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/0-306-46825-5_28

    authors: Conrad PW,Millhorn DE,Beitner-Johnson D

    更新日期:2000-01-01 00:00:00

  • Retroviral transfer of genes into canine hematopoietic progenitor cells.

    abstract::Amphotropic retroviral vectors containing either the bacterial neomycin phosphotransferase gene or a mutant dihydrofolate reductase gene (DHFR*) were used to infect canine hematopoietic progenitor cells. Successful transfer and expression of both genes in canine hematopoietic progenitor cells has been achieved as meas...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-5571-7_3

    authors: Schuening F,Storb R,Nash R,Stead RB,Kwok WW,Miller AD

    更新日期:1988-01-01 00:00:00

  • Modulation of alpha 2-adrenergic receptors of rat vas deferens by adenosine receptors.

    abstract::The effects of adenosine and its derivatives on binding of alpha 2-adrenergic receptor ligands with homogenates of rat vas deferens were examined. Adenosine and 2-chloradenosine increased the amount of [3H]clonidine binding. ATP had a slight effect, but AMP and adenine had none. The effect of adenosine was inhibited b...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-4805-4_11

    authors: Watanabe Y,Yoshida H

    更新日期:1984-01-01 00:00:00

  • The Initial Stage of Tumorigenesis in Drosophila Epithelial Tissues.

    abstract::Cancer development originates in a single mutant cell transformed from a normal cell, including further evolution of pro-tumor cells through additional mutations into malignant cancer tissues. Data from recent studies, however, suggest that most pro-tumor cells do not develop into tumors but remain dormant within or a...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-030-23629-8_5

    authors: Tamori Y

    更新日期:2019-01-01 00:00:00

  • Marijuana, receptors and immunomodulation.

    abstract::THC, the major psychoactive component of marijuana, has been shown both in humans and experimental animals to have immunomodulatory properties. For example, marijuana smokers may show impaired immunological functions, including deficiency of blood leukocyte blastogenesis to mitogens. Detailed studies with mice have sh...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4615-1951-5_15

    authors: Friedman H,Klein TW,Newton C,Daaka Y

    更新日期:1995-01-01 00:00:00

  • "Large" Tank Acoustics: How Big Is Big Enough?

    abstract::In this paper, we discuss the issues encountered when trying to perform hearing experiments in water-filled tanks that are several meters in lateral extent, typically large in terms of the size of the animals under study but not necessarily so with respect to the wavelengths of interest. This paper presents measuremen...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4939-2981-8_43

    authors: Gray MD,Rogers PH,Popper AN,Hawkins AD,Fay RR

    更新日期:2016-01-01 00:00:00

  • Co-administration of Microbubbles and Drugs in Ultrasound-Assisted Drug Delivery: Comparison with Drug-Carrying Particles.

    abstract::There are two alternative approaches to ultrasound-assisted drug delivery. First, the drug can be entrapped into or attached onto the ultrasound-responsive particles and administered in the vasculature, to achieve ultrasound-triggered drug release from the particles and localized tissue deposition in response to ultra...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-22536-4_12

    authors: Suzuki R,Klibanov AL

    更新日期:2016-01-01 00:00:00

  • Effects on blood pressure of intracerebroventricular administration of a kinin antagonist.

    abstract::The components of the kallikrein kinin system are present in brain, and blood pressure is increased when kinins are injected into the brain cerebral ventricles. Therefore, brain kinins may play a role in the regulation of blood pressure. Kinin analogs which are effective as blockers of the vasodilatory and musculotrop...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-9543-4_67

    authors: Yang XP,Carretero OA,Akahoshi M,Scicli AG

    更新日期:1989-01-01 00:00:00

  • Epidemiology of asthma: prevalence and burden of disease.

    abstract::While clinical guidelines clearly define mechanisms for asthma diagnosis based upon history, lung function testing, symptoms, and physical examination, surveillance for asthma is much less straightforward. Epidemiologists have long debated the best means of assessing the scope and burden of asthma, seeking to reduce t...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4614-8603-9_2

    authors: Croisant S

    更新日期:2014-01-01 00:00:00

  • Preventing urinary tract infections in early childhood.

    abstract::Urinary tract infection (UTI) is common in children, causes them considerable discomfort, as well as distress to parents and has a tendency to recur. Approximately 20% of those children who experience one infection will have a repeat episode. Since 1975, 11 trials of long-term antibiotics compared with placebo or no t...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4614-4726-9_18

    authors: Williams GJ,Craig JC,Carapetis JR

    更新日期:2013-01-01 00:00:00

  • Transamniotic Stem Cell Therapy.

    abstract::Transamniotic stem cell therapy (TRASCET) is a novel prenatal therapeutic alternative for the treatment of congenital anomalies. It is based upon the principle of augmenting the pre-existing biological role of select populations of fetal stem cells for targeted therapeutic benefit. For example, amniotic fluid-derived ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/5584_2019_416

    authors: Lazow SP,Fauza DO

    更新日期:2020-01-01 00:00:00

  • Relationship Between Cerebral Oxygenation and Metabolism During Rewarming in Newborn Infants After Therapeutic Hypothermia Following Hypoxic-Ischemic Brain Injury.

    abstract::Therapeutic hypothermia (TH) has become a standard of care following hypoxic ischemic encephalopathy (HIE). After TH, body temperature is brought back to 37 °C over 14 h. Lactate/N-acetylasperatate (Lac/NAA) peak area ratio on proton magnetic resonance spectroscopy ((1)H MRS) is the best available outcome biomarker fo...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-319-38810-6_33

    authors: Mitra S,Bale G,Meek J,Uria-Avellanal C,Robertson NJ,Tachtsidis I

    更新日期:2016-01-01 00:00:00

  • Biological diversity of cytochrome P450 redox partner systems.

    abstract::Cytochrome P450 enzymes (P450s or CYPs) catalyze an enormous variety of oxidative reactions in organisms from all major domains of life. Their monooxygenase activity relies on the reductive scission of molecular oxygen (O2) bound to P450 heme iron, and thus on the delivery of two electrons to the heme iron at discrete...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-16009-2_11

    authors: McLean KJ,Luciakova D,Belcher J,Tee KL,Munro AW

    更新日期:2015-01-01 00:00:00

  • On building a memory evolutive system for application to learning and cognition modeling.

    abstract::We address here aspects of the implementation of a memory evolutive system (MES), based on the model proposed by A. Ehresmann and J. Vanbremeersch (2007), by means of a simulated network of spiking neurons with time dependent plasticity. We point out the advantages and challenges of applying category theory for the re...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-0-387-79100-5_2

    authors: de Lima do Rego Monteiro J,Kogler JE,Ribeiro JH,Netto ML

    更新日期:2010-01-01 00:00:00

  • A Mini Review: Moving iPSC-Derived Retinal Subtypes Forward for Clinical Applications for Retinal Degenerative Diseases.

    abstract::Patient-derived human-induced pluripotent stem cells (iPSCs) have been critical in advancing our understanding of the underlying mechanisms of numerous retinal disorders. Many of these retinal disorders have no effective treatment and result in severe visual impairment and even blindness. Among the retinal degenerativ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-030-27378-1_91

    authors: Cho C,Duong TT,Mills JA

    更新日期:2019-01-01 00:00:00

  • Aquaporins in Digestive System.

    abstract::In this chapter, we mainly discuss the expression and function of aquaporins (AQPs ) expressed in digestive system . AQPs in gastrointestinal tract include four members of aquaporin subfamily: AQP1, AQP4, AQP5 and AQP8, and a member of aquaglyceroporin subfamily: AQP3. In the digestive glands, especially the liver, we...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-94-024-1057-0_8

    authors: Zhu S,Ran J,Yang B,Mei Z

    更新日期:2017-01-01 00:00:00

  • Oxygen dependence of energy state and cardiac work in the perfused rat heart.

    abstract::The relationship between oxygen concentrations in arteries, cytosol, and mitochondria and high energy phosphate metabolism was studied in perfused rat hearts subjected to low and high workloads during gradual hypoxia. PCr, ATP, and Pi were measured by 31P-NMR. Myoglobin oxygenation and cytochrome aa3 oxidation were me...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-8181-5_50

    authors: Ito K,Nioka S,Chance B

    更新日期:1990-01-01 00:00:00

  • Enhancing Nursing Education Through Affordable and Realistic Holographic Mixed Reality: The Virtual Standardized Patient for Clinical Simulation.

    abstract::Nurses serve a valuable role in the healthcare industry. Nurses are trained with the skills and knowledge to thrive in a fast-paced, evolving environment. In order to meet the complex and diverse needs of patients, nurses must be able to assess and prioritize care to produce safe and high-quality outcomes. Simulation ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-030-06070-1_1

    authors: Hauze SW,Hoyt HH,Frazee JP,Greiner PA,Marshall JM

    更新日期:2019-01-01 00:00:00