Abstract:
:Early changes of the activity of enzymes such as creatine kinase in the cerebrospinal fluid (CSF) or serum are often investigated after head injuries to assess the extent of brain damage and establish a reliable prognosis. The purpose of the present study was to determine levels of creatine kinase isoenzyme CK-BB in the CSF of rats after experimental head injuries. External head injuries of different severity were inflicted on rats, immediately after which CSF was collected for isoenzyme activity determination. It was found that the levels of CK-BB were significantly elevated immediately after the head injury and that the greater the degree of external cranial injury inflicted, the higher the isoenzyme activity was. The results seem to provide evidence that CK-BB activity is an early indicator of brain damage and that its level may reflect the extent of cerebral damage involved.
journal_name
Br J Neurosurgjournal_title
British journal of neurosurgeryauthors
Anagnostopoulos DI,Dontas IA,Kotsarelis DV,Julien G,Karayannacos PE,Diakolios CE,Skalkeas GDdoi
10.3109/02688698808992666subject
Has Abstractpub_date
1988-01-01 00:00:00pages
169-72issue
2eissn
0268-8697issn
1360-046Xjournal_volume
2pub_type
杂志文章abstract::Combining previously independently established techniques our objective was to develop and evaluate a method for bedside qualitative assessment of cerebral blood flow in neurointensive care (NICU) patients. The CT-protocol was optimized using phantoms and comparing a mobile CT-scanner (Tomoscan-M, Philips) with two st...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690500389898
更新日期:2005-10-01 00:00:00
abstract::Objective: To evaluate the clinical efficacy, practicability, and safety of an ultrasonic osteotome for percutaneous transforaminal endoscopic discectomy (PTED) in patients with calcified lumbar disc herniation (CLDH).Methods: A total of 25 CLDH patients who underwent PTED at our department between December 2017 and A...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1687850
更新日期:2020-02-01 00:00:00
abstract:INTRODUCTION:There is a high rate of IDH1/2 mutations in low grade gliomas and in high grade gliomas deriving from them. IDH analysis of gliomas is a novel method of classification and an independent prognostic marker. We compared antibody and sequencing methods for the detection of IDH mutations. METHOD:88 samples fr...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.771139
更新日期:2013-08-01 00:00:00
abstract::True posterior communicating artery (PCoA) aneurysm is an aneurysm that originates from the PCoA, and large or giant true PCoA aneurysms are rare. We report a case of a large true PCoA aneurysm successfully clipped after anterior clinoidectomy and discuss the diagnostic pitfalls associated with this rare clinical enti...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688697.2013.771727
更新日期:2013-10-01 00:00:00
abstract::Gliomatosis cerebri (GC), which mainly consists of oligodendroglial tumour cells, is rare and six cases have been documented to date. We present a new case of oligodendroglial gliomatosis cerebri with a favourable response to combination treatment using surgery, radiotherapy and chemotherapy. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688690410001732823
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Solitary Fibrous Tumour (SFT) is a rare tumour occurring mainly in the pleural cavity, with less than 100 cases reported in the Central Nervous System, where it typically presents as a meningeal-based lesion. We describe the case of a SFT located in the fourth ventricle and briefly review the pertinent liter...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688691003675226
更新日期:2010-08-01 00:00:00
abstract:INTRODUCTION:We analyse the factors that are associated with the diagnostic yield of needle brain biopsy. MATERIAL AND METHODS:We present a retrospective series of 124 consecutive biopsies in a 30-month period. Patients' demographics (age, gender), lesion topography (side, location, depth), lesion characteristics (his...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2012.722239
更新日期:2013-04-01 00:00:00
abstract::A true human tail is a rare occurrence and is defined as a caudal, vestigial, midline protrusion with skin covering connective tissue, muscle, vessels and nerves. We report a case of true human tail in a child, which is a very rare happening in humans. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688690902912933
更新日期:2009-12-01 00:00:00
abstract::We describe the case of a fenestrated basilar artery aneurysm successfully clipped by means of a right presigmoid petrosal approach. Three-dimensional CT angiography enabled the surgeon to plan an approach to an aneurysm in this unique location, and the presigmoid petrosal approach was suitable for clipping of the ane...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699845311
更新日期:1998-04-01 00:00:00
abstract:INTRODUCTION:The main treatment modalities for single brain metastases are whole brain radiotherapy (WBRT), surgery and stereotactic radiosurgery. Current guidelines recommend complete surgical excision for single cerebral metastases and two randomised controlled trials (RCT) have also found survival benefit of surgery...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.771729
更新日期:2013-10-01 00:00:00
abstract::The authors report the rare and first documented case of intracranial collision tumour occurrence in a previously evacuated intracerebral haematoma site. Surgery trauma could predispose to collision tumour occurrence. Research efforts should try to reveal the possible pathogenesis of this condition. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2012.697220
更新日期:2012-12-01 00:00:00
abstract::Chordoid glioma, a rare tumour of the third ventricle, has distinctive histological appearances. Fewer than 20 cases have been reported in the literature, all but three in females. This paper describes a 54-year-old man with a chordoid glioma and reviews the clinicopathological features of this lesion. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688690120036865
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVE:The study aims to define the role and indication of surgical intervention in cases of malignant cerebral edema in consequence to cortical venous thrombosis (CVT). METHODS:A retrospective study of 13 patients who underwent decompressive craniectomies for malignant CVT is presented. All patients had supra-tent...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.578775
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:To explore the clinical significance of dynamic monitoring of cerebrospinal fluid (CSF) and serum Lactic acid(Lac), neuron-specific enolase (NSE), and the blood-brain barrier (BBB) index in evaluating the condition and prognosis after a severe traumatic brain injury (TBI). METHODS:A total of 52 severe TBI pa...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1823938
更新日期:2020-10-05 00:00:00
abstract::Twenty patients with aneurysms were studied with transcranial Doppler before, during and after endovascular treatment with Guglielmi detachable coils. Catheterization of the anterior circulation decreased middle cerebral artery velocities by 15-20%. Inserting coils into the aneurysms increased pulsatility indices mode...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699550040710
更新日期:1995-01-01 00:00:00
abstract::In March 2015, the Supreme Court's landmark ruling on the common law case of Montgomery vs Lanarkshire Health Board established the doctrine of informed patient consent, setting the legal standards that doctors should abide by. In this review, our primary aim has been to establish whether, despite the well-publicised ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2018.1519111
更新日期:2018-12-01 00:00:00
abstract::Use of transcranial Doppler (TCD) to diagnose vasospasm has been criticised. We examined reproducibility of TCD middle cerebral artery (MCA) velocity measurements. Thirty-six healthy adult volunteers were recruited. Four operators, two experienced and two inexperienced, participated. MCA velocity was measured twice by...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690701210539
更新日期:2007-02-01 00:00:00
abstract::The debate regarding whether to perform an interbody fusion after anterior cervical discectomy (ACD) has been going on for the last 50 years. Several prospective randomized clinical trials have been performed to evaluate the clinical outcome following anterior cervical discectomy with and without interbody fusion. Non...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690802610249
更新日期:2009-02-01 00:00:00
abstract::We present a case of recurrent vago-glossopharyngeal neuralgia after previous surgery, treated successfully with microvascular decompression using intra-operative neurophysiology monitoring. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2015.1039486
更新日期:2015-01-01 00:00:00
abstract::We present two cases of symptomatic, post-lumbar surgery cauda equina compression due to formation of a dissecting subdural extra-arachnoid cerebrospinal fluid (CSF) collection (hygroma) under tension. In both cases, a small inadvertent durotomy was sustained during the initial surgery. Surgical re-exploration confirm...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.625063
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:Hypertensive spontaneous intracerebral hemorrhages (ICH) cause significant morbidity and mortality. In this study, we aimed to investigate the association between calcium level at admission and outcome in hypertensive ICH patients. METHODS:658 hypertensive ICH patients were enrolled from January 2...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1571162
更新日期:2019-04-01 00:00:00
abstract::The long-term outcome of 78 patients with spinal meningiomas operated on over 20 years at a single neurosurgical unit was analysed. Age, sex and tumour location were similar to those reported by others. Overall, 95% of our patents were independently mobile postoperatively, despite 25% of the group being unable to walk...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699844367
更新日期:1998-12-01 00:00:00
abstract:INTRODUCTION:Patients with cauda equina syndrome (CES) are frequently referred late when neurological damage cannot be reversed. National Guidelines for emergency referral, imaging and treatment of CES contain symptoms and/or signs that are those of late often, irreversible CES. Referral at this stage may be too late f...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688697.2017.1297364
更新日期:2017-06-01 00:00:00
abstract::Seventy patients with spinal arteriovenous malformations (AVMs) referred to the author over a 25-year period (1958-82), were equally divided between congenital, intradural and acquired, dural lesions. Amongst the intradural AVMs, were 22 with subarachnoid haemorrhage (SAH), a presenting feature in 18. The clinical fin...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699209002895
更新日期:1992-01-01 00:00:00
abstract::Microdialysis enables the chemistry of extracellular fluid in body tissues to be measured. Extracellular proteases such as the cysteine protease, cathepsin S (CatS), are thought to facilitate astrocytoma invasion. Microdialysates obtained from human brain tumours in vivo were subjected to cathepsin S activity and ELIS...
journal_title:British journal of neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1080/02688690701248190
更新日期:2007-04-01 00:00:00
abstract::Silver-Russell syndrome is a rare genetically heterogeneous disorder in which patients demonstrate intrauterine and postnatal growth retardation, triangular facies, excessive sweating during early childhood, late closure of the anterior fontanelle and skeletal asymmetry. An association with malignancy exists and only ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690802044076
更新日期:2008-12-01 00:00:00
abstract::Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) has recently been shown to effectively ameliorate medically intractable axial symptoms of Parkinson's disease (PD). The effects of DBS are not limited to the targeted structure, but will affect the distributed anatomical networks to which the target st...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690802448251
更新日期:2008-01-01 00:00:00
abstract::Twenty unselected pituitary adenomas have been examined for proliferative indices (PIs), and anterior pituitary hormone expression. All but two of the tumours were non-functional with proliferative indices from less than 0.1 to 0.5%. Two tumours were null cell adenomas with PIs less than 0.1 and 0.2%. The PIs of the t...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699209002899
更新日期:1992-01-01 00:00:00
abstract::Pial arteriovenous fistula (AVF) is a rare vascular lesion, with less than 120 reported cases in the English literatures (Hoh et al., Neurosurgery 2001;49(6):1351). The angio-architecture, clinical course and therapeutic options are all different from arteriovenous malformation (AVM), dural AVM or other intracranial v...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688697.2011.566382
更新日期:2011-10-01 00:00:00
abstract::Sixty patients with borderline or frank insufficiency of their cerebrovascular reserve undergoing carotid endarterectomy were given enough short acting barbiturates, during cross clamping of the internal carotid artery, to cause EEG burst suppression. Arterial and venous concentrations of lactate were measured in bloo...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688698909002828
更新日期:1989-01-01 00:00:00