IDH mutation analysis in gliomas as a diagnostic and prognostic biomarker.

abstract：:In the first prospective comparison of 'scan-negative' (n=11) and 'scan-positive' (n=7) patients with cauda equina syndrome (CES) we found that Hoover's sign of functional leg weakness but not routine clinical features differentiated the two groups (p<0.02). This offers a new direction of study in this area, although ...

journal_title：British journal of neurosurgery

authors： Hoeritzauer I,Doherty CM,Thomson S,Kee R,Carson A,Eames N,Stone J

更新日期：2015-04-01 00:00:00

abstract：:Cavernous angiomas affecting the optic pathway are rare. This report describes the case of a 12-year-old girl who presented with a 10-month history of right-sided blurred vision caused by a cavernous angioma affecting the right side of the optic chiasm. The computed tomography (CT) scan demonstrated a hyperdense image...

journal_title：British journal of neurosurgery

authors： Sun XY,Yu F

更新日期：2012-12-01 00:00:00

abstract：:Silver-Russell syndrome is a rare genetically heterogeneous disorder in which patients demonstrate intrauterine and postnatal growth retardation, triangular facies, excessive sweating during early childhood, late closure of the anterior fontanelle and skeletal asymmetry. An association with malignancy exists and only ...

journal_title：British journal of neurosurgery

authors： Fenton E,Refai D,See W,Rawluk DJ

更新日期：2008-12-01 00:00:00

abstract：:The anterior visual pathway (AVP) can be at risk during gamma knife surgery (GKS). There is no standardised published methodology for protecting the AVP. This paper suggests such an approach in relation to the treatment of meningiomas. There were 67 patients with a mean age of 48.8 years and a minimum follow-up of 25 ...

journal_title：British journal of neurosurgery

authors： Ganz JC,El-Shehaby A,Reda WA,Abdelkarim K

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Gross congenital lesions of the nervous system are obvious at birth and usually present early for management and corrective surgery. However in tropical and developing nations, late presentations are common. AIMS:To determine the factors responsible for very late presentations of gross congenital lesions. ...

journal_title：British journal of neurosurgery

authors： Komolafe EO,Komolafe MA,Adeolu AA

更新日期：2008-12-01 00:00:00

abstract：:Symptomatic, paradoxical intracranial tuberculomas is a rare occurrence. A case of tubercular meningitis, developing paradoxical tuberculomas alongside non-functional ventricular catheter is presented. Catheter removal facilitated removal of these paradoxical lesions, with the patient recovering to near-normal state a...

journal_title：British journal of neurosurgery

authors： Mohindra S

更新日期：2012-12-01 00:00:00

abstract：:Stroke like episodes can occur by cortical compression due to changes in intracranial pressure. We report a patient after left hemicraniectomy who presented transient speech arrest after sleeping on the left side. We propose that mechanical compression of the left inferior or superior frontal gyrus led to this episode...

journal_title：British journal of neurosurgery

authors： Wojtecki L,Schnitzler A

更新日期：2011-06-01 00:00:00

abstract：INTRODUCTION:Glioblastomas are the commonest primary brain tumour and are considered one of the most heterogeneous tumour types. The introduction of a glioblastoma with oligodendroglial component (GBM + O) in the latest WHO Classification of Tumours of the Central Nervous System (1) was to help with this. There has bee...

journal_title：British journal of neurosurgery

authors： Elmahdi A,Frary AJ,Scotton WJ,O'Donovan DG,Price SJ

更新日期：2013-08-01 00:00:00

abstract：:A case where the administration of intrathecal gentamycin, used to treat a ventriculitis consequent upon a ventriculoperitoneal shunt infection, with a persistent elevation of the CSF leucocyte count is described. In a situation where the number of white cells in the CSF is taken to indicate resolution of infection, i...

journal_title：British journal of neurosurgery

authors： Lee TK,Kerr RS,Adams CB

更新日期：1989-01-01 00:00:00

abstract：:Brainstem cavernomas can present very challenging operative problems. Endoscopic endonasal approaches to these lesions in the mesencephalon and pons have been described. In this article the authors present the first case of a medullary cavernoma resected by an endoscopic transclival approach. A 26 year-old woman with ...

journal_title：British journal of neurosurgery

authors： Alikhani P,Sivakanthan S,Ashour R,Tabor M,van Loveren H,Agazzi S

更新日期：2019-12-01 00:00:00

abstract：:A case is described where a reconstruction of a complex defect in the floor of anterior cranial fossa was successfully carried out using multiple layers of vascularised pedicle flaps. The 42-year-old male patient had previously undergone multiple surgical procedures for persistent cerebrospinal fluid (CSF) rhinorrhoea...

journal_title：British journal of neurosurgery

authors： Goel A

更新日期：1998-06-01 00:00:00

abstract：:Background: Bow hunter's syndrome (BHS), also known as rotational vertebral artery occlusion syndrome, is rare. Occasionally, it combines with dissection/pseudoaneurysm of the ipsilateral VA.Methods: We report a case of BHS combined with ipsilateral VA dissection/pseudoaneurysm and review eight similar cases reported ...

journal_title：British journal of neurosurgery

authors： Xue S,Shi H,Du X,Ma X

更新日期：2020-02-03 00:00:00

abstract：:This paper proposes guidelines for good practice in the management of adults with malignant cerebral glioma. These guidelines were developed by a working group comprising representatives of the medical specialties involved in patient care, specialist nursing staff, purchasers, charitable bodies, and patient and relati...

journal_title：British journal of neurosurgery

authors： Davies E,Hopkins A

更新日期：1997-08-01 00:00:00

abstract：:We report a 14-year-old boy with cavernous malformation of the optic chiasm. He had a 2-year history of gradually worsening visual disturbance. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a suprasellar mass, findings compatible with craniopharyngioma. The mass was biopsied and histological e...

journal_title：British journal of neurosurgery

authors： Muta D,Nishi T,Koga K,Yamashiro S,Fujioka S,Kuratsu J

更新日期：2006-10-01 00:00:00

abstract：:The aim of this study was to analyse and compare published data during the last decade on the different approaches to Parkinson's disease surgery. Eighty-eight papers published between 1990 and 2001 fulfilled the inclusion criteria. Full-text and prospective papers on lesion and stimulation of GPi or STN were assessed...

journal_title：British journal of neurosurgery

authors： Boucai L,Cerquetti D,Merello M

更新日期：2004-06-01 00:00:00

abstract：:Fibrous dysplasia (FD) is an uncommon benign fibro-osseous abnormality of bone, of unknown aetiology and equal sex incidence, which is most commonly restricted to one bone (monostotic FD: MFD, 70%). Less commonly multiple bones are affected (polyostotic FD: PFD, 27%). Vertebral involvement is uncommon (4%), but more c...

journal_title：British journal of neurosurgery

authors： Marshman LA,David KM,O'Donovan DG,Chawda SJ

更新日期：2004-10-01 00:00:00

abstract：:Chordomas constitute <5% of vertebral column tumours and a third of these arise in the upper cervical spine and tend to be clival - usually midline, with occasional eccentric extension. We report a case of cervical chordoma presenting as a lateral neck mass and discuss its origin, diagnosis and management. ...

journal_title：British journal of neurosurgery

authors： Bannur U,Chawda SJ,O'Donovan DG,Kaddour H,David KM

更新日期：2011-08-01 00:00:00

abstract：:A case is presented of a 35-year-old man, who suffered intermittent hydrocephalic attacks due to a large subependymoma arising within the left lateral ventricle. The sparse literature on this rare tumour is reviewed. ...

journal_title：British journal of neurosurgery

authors： Iqbal Z,Sutcliffe JC

更新日期：1994-01-01 00:00:00

abstract：:Multicentre gliomas are a well recognized entity but the occurrence of such tumours both above and below the tentorium remains uncommon. We report the case of an 11-year-old boy who underwent stereotactic biopsy of a brain stem ring enhancing tumour with histology of an anaplastic astrocytoma (Grade 3). Nine months fo...

journal_title：British journal of neurosurgery

authors： Pell MF,Revesz T,Thomas DG

更新日期：1991-01-01 00:00:00

abstract：:The frontobasal approach remains a workhorse for removing large olfactory groove meningiomas. Removal of the orbital bar in addition to standard bifrontal craniotomy allows for additional basal exposure, minimising brain retraction and allowing early and direct access to both the vascular supply and dural origin of th...

journal_title：British journal of neurosurgery

authors： Patel K,Kolias AG,Kirollos RW

更新日期：2016-01-01 00:00:00

abstract：:Surgical approaches to the posterior fossa may be complicated by pseudomeningocoele formation. We report on its natural history and risk factors for its formation, as seen on serial MRI postoperatively in children with posterior fossa tumours. In a retrospective study of 84 children undergoing surgery for posterior fo...

journal_title：British journal of neurosurgery

authors： Gnanalingham KK,Lafuente J,Thompson D,Harkness W,Hayward R

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To assess surgical results and quality of life after removal of tumours causing ventral compression of the brainstem using the presigmoid or combined presigmoid/retrosigmoid approaches. METHODS:A review of all our patients operated on with removal of tumours causing ventral compression of the brainstem in wh...

journal_title：British journal of neurosurgery

authors： Frič R,Eide PK

更新日期：2011-02-01 00:00:00

abstract：:Objective: Vaccination therapy using tumour antigen-loaded, autologous dendritic cells (DC) is a promising therapeutic approach alongside standard treatment for glioblastoma (GBM). However, reliable diagnostic criteria regarding therapy monitoring are not established. Here, we analysed the impact of additional 18F-flu...

journal_title：British journal of neurosurgery

authors： Kristin Schmitz A,Sorg RV,Stoffels G,Grauer OM,Galldiks N,Steiger HJ,Kamp MA,Langen KJ,Sabel M,Rapp M

更新日期：2019-08-13 00:00:00

abstract：INTRODUCTION:The main treatment modalities for single brain metastases are whole brain radiotherapy (WBRT), surgery and stereotactic radiosurgery. Current guidelines recommend complete surgical excision for single cerebral metastases and two randomised controlled trials (RCT) have also found survival benefit of surgery...

journal_title：British journal of neurosurgery

authors： Lim CS,Grundy PL

更新日期：2013-10-01 00:00:00

abstract：:Endovascular treatment of ruptured intracranial aneurysms increasingly supersedes surgical repair. This study focuses on the management and results in 109 individuals treated surgically when both treatment modalities were available. The management principles were immediate identification of the origin of haemorrhage, ...

journal_title：British journal of neurosurgery

authors： Sorteberg W,Slettebø H,Eide PK,Stubhaug A,Sorteberg A

更新日期：2008-02-01 00:00:00

abstract：:Amplification and overexpression of proto-oncogenes are associated with the malignant nature of some human tumours. In this study we have determined the prevalence of amplification of the proto-oncogenes c-erb B1 (= epidermal growth factor receptor gene), c-erb B2 and c-myc in 44 human intracranial tumours (27 gliomas...

journal_title：British journal of neurosurgery

authors： Helseth E,Unsgaard G,Dalen A,Fure H,Skandsen T,Odegaard A,Vik R

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:There are few agreed quantifiable outcome measures in pituitary surgery. The goal of this study is to present the measurement of resection volume after surgery for pituitary tumours as a surgeon-specific outcome measure that may have use in illustrating the performance of individual surgeons internally and ex...

journal_title：British journal of neurosurgery

authors： Phillips N,Tyagi A,Marks P,Nix P

更新日期：2014-06-01 00:00:00

abstract：:Spinal cord stimulation (SCS) is an established treatment modality for chronic pain, angina pectoris, and peripheral vascular disease. This study evaluates experience with SCS over a 13-year period with emphasis on surgical complications, revisions and pain relief. It took the form of a retrospective study of medical/...

journal_title：British journal of neurosurgery

authors： Kay AD,McIntyre MD,Macrae WA,Varma TR

更新日期：2001-08-01 00:00:00

abstract：:A process has been developed by which ventriculoperitoneal hydrocephalus shunts, which are prone to bacterial colonisation, can be impregnated with antimicrobials in order to confer antibacterial activity. Concern that their use might be associated with an increased risk of postoperative seizures has been addressed he...

journal_title：British journal of neurosurgery

authors： Abed WT,Alavijeh MS,Bayston R,Shorvon SD,Patsalos PN

更新日期：1994-01-01 00:00:00

abstract：:Since 1976, 133 patients treated by posterior fossa microvascular decompression (MVD) for trigeminal neuralgia (TN) have been followed-up prospectively to determine the incidence of recurrent TN. The follow-up period was between 6 months and 15 years, with 60 patients having been follow-up for more than 5 years. Of th...

journal_title：British journal of neurosurgery

authors： Mendoza N,Illingworth RD

更新日期：1995-01-01 00:00:00