Abstract:
BACKGROUND:Gross congenital lesions of the nervous system are obvious at birth and usually present early for management and corrective surgery. However in tropical and developing nations, late presentations are common. AIMS:To determine the factors responsible for very late presentations of gross congenital lesions. METHODS:We conducted a prospective study of all cases of congenital CNS anomalies that presented very late (>6 months after birth) to our neurosurgical clinic over an eight year period (2000-2008). RESULTS:A total of 81 patients were seen during the study period. The age ranged from 6 months to 47 years. Hydrocephalus accounted for about half of the cases 37 (48.3%). The others were spina bifida 15 (18.5%), encephalocele 10 (12.4%), subgaleal inclusion dermoid cyst 7 (8.6%), and craniosynostosis 6 (7.4%), neurofibroma 4(4.9%), and anencephaly 2 (2.5%). Reasons given for late presentations were ignorance, poverty and in some the expectation that the baby would die. Other reasons for late presentation were that the patient was either about to start school or get married. CONCLUSION:Late presentations of congenital CNS lesions are associated with many complications most of which could have been avoided with early medical treatment. Health education should include issues regarding congenital malformations delivered by trained experts.
journal_name
Br J Neurosurgjournal_title
British journal of neurosurgeryauthors
Komolafe EO,Komolafe MA,Adeolu AAdoi
10.1080/02688690802485113subject
Has Abstractpub_date
2008-12-01 00:00:00pages
764-8issue
6eissn
0268-8697issn
1360-046Xpii
906650247journal_volume
22pub_type
杂志文章abstract::Purpose: To depict the specific brain networks that are modulated by deep brain stimulation (DBS) of the subthalamic nucleus (STN) in Parkinson's disease (PD), using diffusion tensor imaging-based fibre tractography (DTI-FT).Materials and methods: Nine patients who received bilateral STN-DBS for PD were included. Elec...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1701630
更新日期:2020-04-01 00:00:00
abstract::Amplification and overexpression of proto-oncogenes are associated with the malignant nature of some human tumours. In this study we have determined the prevalence of amplification of the proto-oncogenes c-erb B1 (= epidermal growth factor receptor gene), c-erb B2 and c-myc in 44 human intracranial tumours (27 gliomas...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688698808992672
更新日期:1988-01-01 00:00:00
abstract::Several studies have demonstrated an association between arterial hypertension (AH) and an increased morbidity and mortality from both cardiovascular diseases and stroke (including subarachnoid haemorrhage, SAH). Among the functional disturbances implicated in hypertension much interest has been focused on the calcium...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699108998477
更新日期:1991-01-01 00:00:00
abstract::Intraparenchymal meningiomas are rare. To date, no such lesion has been reported within the basal ganglia of a paediatric patient. Here, we describe the case of a 15-year-old-boy who presented with symptoms referable to a cystic, calcified, left basal ganglia intraparenchymal meningioma and discuss the surgical manage...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2015.1096910
更新日期:2016-06-01 00:00:00
abstract::Purpose: Today, stereotactic surgery (SRS) is among the treatment options for many intracranial lesions including vascular pathologies. One of the most common late complications of SRS is perilesional edema which can be treated with steroids. In addition to steroids, some new medical therapies are being investigated a...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1742294
更新日期:2020-03-27 00:00:00
abstract:BACKGROUND:The graft site morbidity following iliac crest harvesting is significant. To overcome this, different bone substitutes like coral dowels, solvent dissolved bovine/human bone substitutes, and carbon fiber/titanium cages have been used. This study was undertaken to assess the postoperative radiological fusion ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2017.1297362
更新日期:2017-06-01 00:00:00
abstract::Cytogenetic studies over many years have established absence or deletion of chromosome 22 as a common finding in meningiomas. Enormous karyotypic variation is recognised: an abnormal hyperdiploid clone can occur in a histologically benign meningioma. The cytogenetic, histopathological and macroscopic findings in 13 me...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688698909002850
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:The study aims to define the role and indication of surgical intervention in cases of malignant cerebral edema in consequence to cortical venous thrombosis (CVT). METHODS:A retrospective study of 13 patients who underwent decompressive craniectomies for malignant CVT is presented. All patients had supra-tent...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.578775
更新日期:2011-06-01 00:00:00
abstract::The classical presentation of a ruptured intracranial aneurysm is subarachnoid haemorrhage (SAH). We present a rare case of a ruptured posterior communicating artery (PcomA) aneurysm presented solely with massive intraventricular haemorrhage (IVH) in a 53-year-old female. The aneurysm was coiled successfully and the o...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2017.1406451
更新日期:2019-10-01 00:00:00
abstract:INTRODUCTION:Society of British Neurological Surgeons (SBNS) meetings are important national events which allow for the presentation of current academic work. The publication rate of presented abstracts is considered a proxy marker of the scientific strength of a conference. We aimed to determine the publication fate o...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2014.915008
更新日期:2015-04-01 00:00:00
abstract::Purpose: The purpose of this study was to validate the cauda scale (TCS) in an external population. TCS was proposed as a tool to be used to predict the likelihood of cauda equina compression.Methods: We analysed the presenting condition of consecutive patients attending the emergency department undergoing a magnetic ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1754337
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Nowadays the endoscopic endonasal approach is increasingly being used to remove craniopharyngiomas, tuberculum sellae meningiomas and other presellar and parasellar lesions and its value in anterior skull base surgery is undisputed. Herein, we assess the relative advantages, disadvantages and feasibility of ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2018.1480748
更新日期:2018-10-01 00:00:00
abstract::We report the fourth case of Carbapenem-resistant Klebsiella pneumoniae (CRKP) meningitis and the only one associated with brain abscess formation. A 29-years-old male patient developed septic shock 13 days after a right nasopharyngeal AVM resection. CRKP was grown from CSF with a MIC for meropenem ≥16 mg/L. Intraveno...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2018.1530729
更新日期:2019-07-25 00:00:00
abstract::Total excision is usually the recommended treatment for central neurocytomas. The role of radiation therapy in their management is controversial, and is usually reserved for partially resected or recurrent tumours. Long-term outcome was studied in patients with central neurocytoma who were treated with radiation thera...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690220131714
更新日期:2002-04-01 00:00:00
abstract::Isolated intrasellar pituitary mucocele following transsphenoidal sinus surgery is extremely rare. The clinical features resemble a pituitary tumor, therefore careful radiological interpretation is crucial to reach the correct diagnosis. We report a case of intrasellar mucocele who had transsphenoidal sinus surgery pe...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.817535
更新日期:2014-06-01 00:00:00
abstract::A case is described where a reconstruction of a complex defect in the floor of anterior cranial fossa was successfully carried out using multiple layers of vascularised pedicle flaps. The 42-year-old male patient had previously undergone multiple surgical procedures for persistent cerebrospinal fluid (CSF) rhinorrhoea...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699845096
更新日期:1998-06-01 00:00:00
abstract::We report a case of plasma cell granuloma which is a rare intracranial tumour showing plasma cell infiltration. It mimics meningioma and solitary plasmacytoma clinically and radiologically. Clinical presentation, diagnostic investigations and management are discussed with a review of the literature. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688690050175382
更新日期:2000-10-01 00:00:00
abstract::Background: The chronic constriction injury (CCI) of the infraorbital nerve (ION) has been used to establish an animal mode of trigeminal neuralgia (TN), but key parameters of the model have not been quantified until now. Objective: The aim of the study was to quantify a standard of pain threshold to evaluate a succes...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2018.1538483
更新日期:2019-08-01 00:00:00
abstract::The debate regarding whether to perform an interbody fusion after anterior cervical discectomy (ACD) has been going on for the last 50 years. Several prospective randomized clinical trials have been performed to evaluate the clinical outcome following anterior cervical discectomy with and without interbody fusion. Non...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690802610249
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVES:There is a dearth of comparative outcome data on vertebroplasty for the treatment of vertebral compression fractures (VCF) according to vertebral level, the number of levels and aetiology. The aim of this study was to investigate the improvement of pain and function following vertebroplasty for a heterogeneo...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2015.1096901
更新日期:2016-01-01 00:00:00
abstract::A subdural empyema with a Salmonella species as the likely causative organism is presented. We believe that this is the first reported case of such an infection in an HIV positive patient. The difficulties in treatment and diagnosis are discussed. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699550041818
更新日期:1995-01-01 00:00:00
abstract::Distant intraventricular metastasis is extremely rare in childhood craniopharyngioma. Here, we report the isolated posterior ventricular recurrence of an adamantinomatous craniopharyngioma, in a child previously treated with surgery and proton beam therapy for local progression. The importance of surveillance imaging ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688697.2016.1139050
更新日期:2017-08-01 00:00:00
abstract::We report a 14-year-old boy with cavernous malformation of the optic chiasm. He had a 2-year history of gradually worsening visual disturbance. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a suprasellar mass, findings compatible with craniopharyngioma. The mass was biopsied and histological e...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690601000238
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Bilateral anterior cingulotomy is a palliative procedure occasionally used for cancer pain, and human studies suggest anterior cingulate cortex is active in dyspnoeic states. OBJECTIVES:A case of debilitating thoracic wall pain due to malignant mesothelioma relieved by bilateral anterior cingulotomy is desc...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.857006
更新日期:2014-08-01 00:00:00
abstract::Traumatic pseudoaneurysms of the superficial temporal artery are uncommon. They present to a variety of specialities - orthopaedics, ear, nose and throat, neurosurgery, maxillofacial, plastic surgery, vascular surgery and dermatology. Experience managing these lesions is therefore limited and diluted. We present a cas...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690600777034
更新日期:2006-06-01 00:00:00
abstract::The implementation of the two-week wait initiative for cancer referrals in the NHS has had a major impact on outpatient services. A low clinical detection rate among GPs for neurological cancer has resulted in a large number of urgent referrals with a low yield of positive diagnoses. We have devised a strategy for min...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690500305365
更新日期:2005-08-01 00:00:00
abstract::Chiari malformations are a pathological continuum of hindbrain maldevelopment and Chiari I malformation (CMI) represents caudal decent of cerebellar tonsils. The surgery aims to relieve tonsillar compression with restoration of the normal cerebrospinal (CSF) flow dynamics. We report the salient features of our surgica...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690801894638
更新日期:2008-06-01 00:00:00
abstract::From autopsy and neuroradiological studies a maximum prevalence of unruptured intracranial aneurysms (UA) of 0.5% in the general population is revealed. Studies concerning the incidence of aneurysmal subarachnoid haemorrhage (SAH) revealed 10 cases per 100,000 inhabitants per year. From these epidemiological parameter...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688698809001008
更新日期:1988-01-01 00:00:00
abstract::Neurosurgical shunts occasionally act as a conduit for seeding of central nervous system tumours to the abdomen. Retrograde spread of extra-neural tumours to the central nervous system is exceedingly rare. We report the first case of an abdominal primary tumour spreading to the spinal cord via a lumbo-peritoneal shunt...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1679353
更新日期:2020-12-01 00:00:00
abstract::Few data are available concerning the outcome of surgical removal of intracranial meningioma in elderly patients. Surgical criteria and prognostic factors are considerations in the decision as to whether neurosurgical removal should be attempted in elderly patients. The present study appears to be the first to examine...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690151127608
更新日期:2001-04-01 00:00:00