Abstract:
:Several studies have demonstrated an association between arterial hypertension (AH) and an increased morbidity and mortality from both cardiovascular diseases and stroke (including subarachnoid haemorrhage, SAH). Among the functional disturbances implicated in hypertension much interest has been focused on the calcium handling in the vascular smooth muscle cells, and it has been proposed that a defect in the calcium gating mechanisms in the cell membrane is of major importance. Clinical trials have confirmed that calcium antagonists of the dihydropyridine type (nimodipine) are useful in preventing secondary ischaemia after SAH. The purpose of this retrospective study was to determine if the protective effect of nimodipine differs between normotensive and hypertensive patients focused on delayed ischaemia, total morbidity and mortality. In the group (137 patients) without nimodipine treatment 17 out of 31 individuals (55%) with AH had an unfavourable outcome. In the nimodipine group (also 137 patients) four out of 25 individuals (16%) with AH had an unfavourable outcome. In terms of vasospasm and delayed ischaemia only, the difference was even more evident. These results indicate that nimodipine seems to significantly reduce the prognostic difference between normo- and hypertensive individuals with an aneurysmal SAH.
journal_name
Br J Neurosurgjournal_title
British journal of neurosurgeryauthors
Brandt L,Säveland H,Romner B,Ryman Tdoi
10.3109/02688699108998477subject
Has Abstractpub_date
1991-01-01 00:00:00pages
485-9issue
5eissn
0268-8697issn
1360-046Xjournal_volume
5pub_type
杂志文章abstract::We present this unusual case of a 60-year-old gentleman who presented with meningism and reduced conscious level. Imaging demonstrated a perforated sigmoid colon with retroperitoneal air associated with pneumorrhachis and pneumocranium. He required a Hartmann's procedure and broad spectrum intra-thecal antibiotics whi...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2010.500420
更新日期:2011-02-01 00:00:00
abstract::Multicentre gliomas are a well recognized entity but the occurrence of such tumours both above and below the tentorium remains uncommon. We report the case of an 11-year-old boy who underwent stereotactic biopsy of a brain stem ring enhancing tumour with histology of an anaplastic astrocytoma (Grade 3). Nine months fo...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699109002887
更新日期:1991-01-01 00:00:00
abstract:UNLABELLED:Object/Background: Vasospasm is a common cause of mortality and morbidity following rupture of intracranial aneurysm. Hemodynamic therapy instituted in these patients in the past has been replaced by direct manipulation of the spastic vessels by angioplasty and intra-arterial infusion of vasodilators. Howeve...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2016.1161172
更新日期:2016-08-01 00:00:00
abstract::Two patients presented with nocardial brain abscesses, one as secondary to overwhelming pulmonary infection following a thoracic empyema, the second as a primary abscess. Both patients had immunopression. Such an infection should be considered early in any patient who is immunocompromised. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699408995123
更新日期:1994-01-01 00:00:00
abstract::A case of primary Ewing's sarcoma involving a large portion of the petrous temporal bone in an eighteen month old child is reported. The lesion was treated by radical surgery and adjuvant chemotherapy and radiotherapy. An extremely rare age of presentation, an unusual location and an excellent response to treatment ar...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688690050004606
更新日期:2000-04-01 00:00:00
abstract:AIM:The aim of this manuscript is to review the current state of knowledge regarding C-reactive protein (CRP) kinetics after standard neurosurgical procedures, and to determine the value of CRP as a screening test for early post-operative infectious complications as opposed to other more commonly used tests, and as a m...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2010.500408
更新日期:2010-12-01 00:00:00
abstract::In vestibular schwannomas (VS), the tumour size, as well as the size of the cystic component, have a considerable bearing on the outcome. This study addresses the differences between the cystic and solid variants of giant vestibular schwannomas. The study included 62 patients with giant VSs, of which 40 were solid and...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690802159031
更新日期:2008-08-01 00:00:00
abstract::A case is described where a reconstruction of a complex defect in the floor of anterior cranial fossa was successfully carried out using multiple layers of vascularised pedicle flaps. The 42-year-old male patient had previously undergone multiple surgical procedures for persistent cerebrospinal fluid (CSF) rhinorrhoea...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699845096
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Bilateral anterior cingulotomy is a palliative procedure occasionally used for cancer pain, and human studies suggest anterior cingulate cortex is active in dyspnoeic states. OBJECTIVES:A case of debilitating thoracic wall pain due to malignant mesothelioma relieved by bilateral anterior cingulotomy is desc...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.857006
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to identify independent anatomic, morphologic and hemodynamic features of the ACoA (anterior communicating artery) complex that serve as risk factors for the occurrence of ACoA aneurysms. METHODS:Fifteen consecutive patients with 15 ACoA aneurysms were included. Computational fluid ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1821867
更新日期:2020-09-29 00:00:00
abstract::Background: Vertebral body compression fractures are one of the most common causes of disability and morbidity, especially among the elderly population. The present study was performed in order to evaluate the effect of percutaneous balloon kyphoplasty (BKP) on patients' pain and quality of life (QOL) in Iran.Methods:...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1777254
更新日期:2020-06-09 00:00:00
abstract::Tonsillar herniation is a rare and seldom reported complication after lumboperitoneal (LP) shunting. There have been only few reports that have presented possible options for treatment with varying degrees of success. In this report, we describe a rare case of tonsillar herniation after LP shunting and review related ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2018.1538481
更新日期:2018-12-06 00:00:00
abstract:OBJECTIVES:Patients with moyamoya disease (MMD) very rarely develop both cerebral ischaemia and haemorrhage. The aim of this study was to clarify the clinical and radiographic features of MMD in patients who presented with both ischaemia and haemorrhage, compared with MMD patients who presented with one or the other. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2012.717983
更新日期:2013-04-01 00:00:00
abstract::Venous oxygen saturation at the clinically dominant jugular bulb (SjO2) and that at the confluence of the cerebral sinuses (SccsO2) were compared by direct simultaneous blood sampling of 13 severely head injured patients. The side of dominant jugular bulb (JB) was determined by neck compression test. The right side wa...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699647276
更新日期:1996-08-01 00:00:00
abstract::Background: When treating intracranial aneurysms with open microsurgery, rare cases arise in which an ipsilateral approach leads to poor visualization, lack of proximal control, or potential damage to nearby vital structures due to the anatomy of the aneurysm. Case Description: We describe a patient with a small, unru...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1648754
更新日期:2019-07-31 00:00:00
abstract:PURPOSE:The purpose of this study was to analyse all cases of spinal osteosarcoma (OS) treated in a regional bone tumour unit over the last 27 years. We were primarily interested in overall survival following tumour surgery, and if there is a difference in the survival of patients undergoing en bloc resection versus no...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.869550
更新日期:2014-08-01 00:00:00
abstract::Cavernous angiomas affecting the optic pathway are rare. This report describes the case of a 12-year-old girl who presented with a 10-month history of right-sided blurred vision caused by a cavernous angioma affecting the right side of the optic chiasm. The computed tomography (CT) scan demonstrated a hyperdense image...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688697.2012.685820
更新日期:2012-12-01 00:00:00
abstract::The previous literature on radiosurgical treatment for craniopharyngioma is sparse, because the involvement of the radiosensitive optic chiasm within the target volume (in most cases) precludes safe high single dosage. The relocatable frame, introduced at St Bartholomew's Hospital in 1989, utilizes the dosimetric adva...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699943448
更新日期:1999-08-01 00:00:00
abstract:OBJECTIVE:Evidence suggests that reduction of nitric oxide (NO) bioavailability due to oxidative stress plays a central role in the pathophysiology of cerebral vasospasm after subarachnoid haemorrhage (SAH). To prevent SAH-induced cerebral vasospasm, therefore we used nebivolol hydrochloride as a NO-mediated vasodilato...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2017.1297367
更新日期:2017-08-01 00:00:00
abstract::The debate regarding whether to perform an interbody fusion after anterior cervical discectomy (ACD) has been going on for the last 50 years. Several prospective randomized clinical trials have been performed to evaluate the clinical outcome following anterior cervical discectomy with and without interbody fusion. Non...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690802610249
更新日期:2009-02-01 00:00:00
abstract::In this study we present the population-based patient material with spontaneous SAH, treated in our Neurosurgical unit during the 10 years (1997-2006) after the introduction of endovascular treatment of aneurysms (EVT) in our hospital. All patients that had a spontaneous SAH and a potential to survive were admitted. T...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690902874901
更新日期:2009-01-01 00:00:00
abstract::There are two reported cases of ependymomas arising in the pituitary fossa; one in a human, the other in a horse. Both died during their stay in hospital. The case presented here is the first published case of a patient who is well 3 months after surgery. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/026886901750353764
更新日期:2001-06-01 00:00:00
abstract::A system of stereotactic radiosurgery using a linear accelerator is described and the experience with a variety of neurosurgical lesions including gliomas, acoustic neurinomas and arteriovenous malformations is recorded. The system is simple, inexpensive and effective and can be used with any CT scanner and linear acc...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688698909002808
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Deep brain stimulation (DBS) lead revision due to suboptimal therapy is common but there is no standardised protocol. We describe a novel technique using iMRI to perform concurrent new Globus Pallidus Internus (GPi) DBS lead implantation and old lead removal in a dystonia patient. Case-description: A 60-year...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1789556
更新日期:2020-07-10 00:00:00
abstract::Intracranial penetration during attempted nasogastric intubation is a rare, often lethal occurrence. We report the inadvertent introduction of a nasogastric tube intracranially in a neonate following repair of unilateral choanal atresia. Following manual removal of the tube, the patient made a good recovery. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699943547
更新日期:1999-08-01 00:00:00
abstract::A retrospective study of the surgical management of 41 cerebellopontine angle (CPA) meningiomas was performed. All patients were treated by a single surgeon (TTK) over a 25 year period (1967-1992). There were 13 males, 28 females with a median age of 53.5 years. The median follow-up after surgery was 9 years (range 2-...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699650040539
更新日期:1996-02-01 00:00:00
abstract:BACKGROUND:Determining neurological level of injury (NLI) is of paramount importance after spinal cord injury (SCI), although its accuracy depends upon the reliability of the neurologic examination. Here, we determine if anatomic location of cervical cord injury by MRI (MRI level of injury) can predict NLI in the acute...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2015.1056089
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Irrigation may elevate the intracranial pressure (ICP) during neuroendoscopic procedures. It is unlikely that rinsing the ventricles during routine endoscopic ventriculostomy causes persistent neurological impairment or damage, but procedures such as the endoscopic evacuation of intraventricular haematomas (...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.619596
更新日期:2012-04-01 00:00:00
abstract::We present a case of recurrent vago-glossopharyngeal neuralgia after previous surgery, treated successfully with microvascular decompression using intra-operative neurophysiology monitoring. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2015.1039486
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:The study aims to define the role and indication of surgical intervention in cases of malignant cerebral edema in consequence to cortical venous thrombosis (CVT). METHODS:A retrospective study of 13 patients who underwent decompressive craniectomies for malignant CVT is presented. All patients had supra-tent...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.578775
更新日期:2011-06-01 00:00:00