Abstract:
OBJECTIVE:The aim of this study was to identify independent anatomic, morphologic and hemodynamic features of the ACoA (anterior communicating artery) complex that serve as risk factors for the occurrence of ACoA aneurysms. METHODS:Fifteen consecutive patients with 15 ACoA aneurysms were included. Computational fluid dynamics (CFD) simulations based on patient-specific models were carried out using 3D time-of-flight magnetic resonance angiography (3D-TOF-MRA) images. A reverse reconstruction technique was used to generate a pre-aneurysm vessel anatomy. Geometric parameters and hemodynamic changes were compared and evaluated. RESULTS:The overall prevalence of symmetric, dysplastic, and absent A1 segments were 53.3%, 26.7%, and 20%. The mean wall shear stress (WSS) of the absent group (AG) was significantly higher than that of the symmetric group (SG) and dysplastic group (DG). The absolute mean A1 artery flow rate (410.2 ± 88 versus 439.4 ± 101 mL/min; p = .45) of the aneurysm side was similar between the SG and DG but significantly higher in the AG (528.1 ± 77 mL/min; p < .05). The A1-A2 angles of the aneurysm side showed no significant differences among the 3 groups (p = .32). However, the mean A1-A2 angle on the aneurysm side was smaller than the contralateral A1-A2 angle (101.9 ± 9.1˚ versus 120.3 ± 7.7˚; p <.05). A regression analysis demonstrated that high WSS was significantly associated with a large A1-A2 ratio (R2=0.52; p <.05). CONCLUSIONS:ACoA aneurysms are a high-WSS pathology. Severe flow impingement and the anatomic vasculature structures play a role in triggering the occurrence of ACoA aneurysms.
journal_name
Br J Neurosurgjournal_title
British journal of neurosurgeryauthors
Zhou G,Wang J,Liu W,Gu W,Su M,Feng Y,Qin B,Zhu Ydoi
10.1080/02688697.2020.1821867subject
Has Abstractpub_date
2020-09-29 00:00:00pages
1-5eissn
0268-8697issn
1360-046Xpub_type
杂志文章abstract::The classical presentation of a ruptured intracranial aneurysm is subarachnoid haemorrhage (SAH). We present a rare case of a ruptured posterior communicating artery (PcomA) aneurysm presented solely with massive intraventricular haemorrhage (IVH) in a 53-year-old female. The aneurysm was coiled successfully and the o...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2017.1406451
更新日期:2019-10-01 00:00:00
abstract::A 64-year-old Caucasian woman presented with left eye pain and a transient left oculomotor nerve palsy. Subsequent imaging revealed a mass involving the sphenoid sinus and sella with suprasellar extension. A trans-sphenoidal hypophysectomy was performed. Histopathology showed a fungal infection consistent with phaeohy...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690500390417
更新日期:2005-10-01 00:00:00
abstract::A case where the administration of intrathecal gentamycin, used to treat a ventriculitis consequent upon a ventriculoperitoneal shunt infection, with a persistent elevation of the CSF leucocyte count is described. In a situation where the number of white cells in the CSF is taken to indicate resolution of infection, i...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688698909002840
更新日期:1989-01-01 00:00:00
abstract::Survivors of head injury are often left with varying degrees of disability and complex and varied needs, necessitating prolonged periods of rehabilitation and continuing care. Advances have been made in the acute management of these patients, but continuing management in terms of rehabilitation remains deficient with ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690903078874
更新日期:2009-01-01 00:00:00
abstract::We report the use of a twist drill method for placement of external ventricular drains and ventriculoperitoneal shunts. We have found this method to be efficient and safe, and provides an excellent cosmetic effect. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/026886900417333
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:The optic nerve is an unusual site of schwannoma as it lacks Schwannoma cells on it. We report a primary optic sheath schwannoma and to review the literature. CASE REPORT:A 29-year old female presented with progressive painless non-pulsatile proptosis. Ocular examination revealed only axial proptosis. Imagi...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1869181
更新日期:2021-01-08 00:00:00
abstract::This paper proposes guidelines for good practice in the management of adults with malignant cerebral glioma. These guidelines were developed by a working group comprising representatives of the medical specialties involved in patient care, specialist nursing staff, purchasers, charitable bodies, and patient and relati...
journal_title:British journal of neurosurgery
pub_type: 指南,杂志文章,实务指引
doi:10.1080/02688699746104
更新日期:1997-08-01 00:00:00
abstract::The objective of this study was to assess the technical feasibility, and the clinical and radiological results of interbody fusion with a carbon fibre cage following anterior cervical discectomy. Nineteen consecutive patients, eight male and 11 female, with an age range from 28 to 75 years (mean 45) underwent anterior...
journal_title:British journal of neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1080/02688699746285
更新日期:1997-06-01 00:00:00
abstract::The transnasal approach is the most utilized approach to the sellar region. This study was conducted to identify an anatomical landmark on the lateral surface of the head that corresponds to the midpoint of the sellar floor at the level of sphenoidal rostrum. This point, lined up with the nostril, simulates the surgic...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690802630056
更新日期:2009-06-01 00:00:00
abstract::We report a 14-year-old boy with cavernous malformation of the optic chiasm. He had a 2-year history of gradually worsening visual disturbance. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a suprasellar mass, findings compatible with craniopharyngioma. The mass was biopsied and histological e...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690601000238
更新日期:2006-10-01 00:00:00
abstract::Cortical thermal clearance was used during surgery for clipping of a giant middle cerebral artery (MCA) aneurysm. During prolonged continuous proximal MCA occlusion thermal clearance remained normal, indicating sufficient collateral blood supply. Postoperatively the patient had no neurological deficit. This monitoring...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699308995097
更新日期:1993-01-01 00:00:00
abstract::Nosocomial infections, pneumonia in particular, are well-known complications of traumatic brain injury (TBI), which are associated with a worse neurological outcome. This review aims to explore the role of vagus nerve activity in immunomodulation as a causative factor. A MEDLINE search revealed numerous reports publis...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688697.2013.835373
更新日期:2014-04-01 00:00:00
abstract::Aim: to present evidence for the use of endoscopic third ventriculostomy (ETV) in the treatment of holocord syrinx.Methods: ETV has been used in the treatment of obstructive hydrocephalus and syringomyelia secondary to Chiari 1 malformation. However, there have been no reports of ETV being utilised in the management o...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1718603
更新日期:2020-01-29 00:00:00
abstract:OBJECTIVE:To explore the changes of a series of cytokines before and after percutaneous balloon kyphoplasty (PKP) and prognostic markers for response to PKP. METHODS:From 1 January 2019 to 31 May 2019, all single-level lumbar osteoporotic vertebral compression fracture (OVCF) patients diagnosed by MRI who matched the ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1823941
更新日期:2020-10-14 00:00:00
abstract::Twenty-four patients with intractable partial epilepsy underwent surgery between 1969 and 1988. Localization was by non-invasive means using scalp EEG and CT. In 12 cases the focus was temporal and in eight frontal. Craniotomy was undertaken with intraoperative electrocorticography (ECoG). Ten cases had a standard tem...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Neurolymphomatosis typically appears as a diffuse lesion with thickening of the affected nerves on magnetic resonance imaging (MRI). MRI in the present case revealed a well-defined, solitary lesion showing continuity with brachial plexus nerves. Findings including clinical symptoms resembled benign nerve sheath tumour...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2012.737959
更新日期:2013-06-01 00:00:00
abstract::The frontobasal approach remains a workhorse for removing large olfactory groove meningiomas. Removal of the orbital bar in addition to standard bifrontal craniotomy allows for additional basal exposure, minimising brain retraction and allowing early and direct access to both the vascular supply and dural origin of th...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2015.1071329
更新日期:2016-01-01 00:00:00
abstract::Objective: Vaccination therapy using tumour antigen-loaded, autologous dendritic cells (DC) is a promising therapeutic approach alongside standard treatment for glioblastoma (GBM). However, reliable diagnostic criteria regarding therapy monitoring are not established. Here, we analysed the impact of additional 18F-flu...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1639615
更新日期:2019-08-13 00:00:00
abstract::The authors report the rare and first documented case of concomitant microvascular decompression of trigeminal, facial and glossopharyngeal nerves for the management of intractable to medical therapy acute onset of trigeminal neuralgia, facial paresis and dysphagia after mild head injury. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.815327
更新日期:2014-01-01 00:00:00
abstract::A combined approach for microvascular decompression of trigeminal neuralgia is reported. Arachnoid dissection of the cerebellar horizontal fissure (transhorizontal approach) allowed easy identification of the root exit zone of the trigeminal nerve. The superior semilunar lobule was pulled back rostrally so that retrac...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690020005536
更新日期:2000-12-01 00:00:00
abstract::Background: Cholesterol granulomas of the petrous apex are benign cysts affecting 0.6 patients per 1 million. The pathophysiology involves cholesterol crystals and lipids that are surrounded by giant cells. The cholesterol deposits induce an inflammatory response likely from acute hemorrhage leading to the formation o...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1773400
更新日期:2020-06-09 00:00:00
abstract::The goal of this study was to assess the diagnostic accuracy of 16-row multislice computed tomography angiography (CTA) compared with digital subtraction angiography (DSA) in the detection of aneurysm remnants and arterial patency after clipping of intracranial aneurysms. Thirty-seven consecutive patients with 40 clip...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690701630108
更新日期:2008-02-01 00:00:00
abstract::Choroid plexus xanthogranulomas are uncommon lesions that occur almost exclusively in adults; most of them constitute incidental autopsy findings. A case of symptomatic bilateral xanthogranulomas of choroid plexus in a 6 year-old girl with progressive visual loss is reported. Theories on the pathogenesis of this entit...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690042960
更新日期:2000-02-01 00:00:00
abstract::The anterior visual pathway (AVP) can be at risk during gamma knife surgery (GKS). There is no standardised published methodology for protecting the AVP. This paper suggests such an approach in relation to the treatment of meningiomas. There were 67 patients with a mean age of 48.8 years and a minimum follow-up of 25 ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688690903536611
更新日期:2010-06-01 00:00:00
abstract::We report the first case of primary central nervous system lymphoma (PCNSL) developing in a patient with rheumatoid arthritis (RA) undergoing low-dose methotrexate therapy (LD-MTX). The characteristic clinical management and course in our experience of the present case illustrate the important points about PCNSL in me...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.798857
更新日期:2013-12-01 00:00:00
abstract::A case of spontaneous haemorrhage in a cerebellar abscess is reported. Only two reports of this complication have been found in the literature. An incidental acoustic schwannoma was also found close to the abscess. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699008992729
更新日期:1990-01-01 00:00:00
abstract::Cerebellar haemangioblastomas commonly arise in patients with von Hippel - Lindau disease. We present the case of a 47-year-old male who has successfully undergone 10 separate procedures for symptomatic cerebellar haemangioblastomas. To our knowledge, this case is unique with respect to the frequency of symptomatic re...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690701552864
更新日期:2008-02-01 00:00:00
abstract::We present two cases of symptomatic, post-lumbar surgery cauda equina compression due to formation of a dissecting subdural extra-arachnoid cerebrospinal fluid (CSF) collection (hygroma) under tension. In both cases, a small inadvertent durotomy was sustained during the initial surgery. Surgical re-exploration confirm...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.625063
更新日期:2012-06-01 00:00:00
abstract::Chordomas constitute <5% of vertebral column tumours and a third of these arise in the upper cervical spine and tend to be clival - usually midline, with occasional eccentric extension. We report a case of cervical chordoma presenting as a lateral neck mass and discuss its origin, diagnosis and management. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2010.508959
更新日期:2011-08-01 00:00:00
abstract::Traumatic brain injury (TBI) and acute ischaemic stroke are major causes of mortality and morbidity and there is an urgent demand for new neuroprotective strategies following the translational failure of neuroprotective drug trials. Oxygen therapy--especially normobaric, may offer a simple and effective therapeutic st...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688690903050352
更新日期:2009-12-01 00:00:00