Abstract：
:In vestibular schwannomas (VS), the tumour size, as well as the size of the cystic component, have a considerable bearing on the outcome. This study addresses the differences between the cystic and solid variants of giant vestibular schwannomas. The study included 62 patients with giant VSs, of which 40 were solid and 22 were cystic (those in which cystic component greater or equal to 30% of the total tumour volume). The cystic tumour group was further divided into type A (31-60% volume of the cyst within tumour), type B (61-90% intra-tumoural cyst volume) and type C (more than 90% volume of the cyst). The clinicoradiological features, operative findings, histopathological characteristics and outcome of surgery of the two groups were compared. The mean duration of symptoms for the solid and cystic tumours were 21.1 and 26.2 months, respectively. However, six patients with cystic tumours showed recent and rapid neurological deterioration after a protracted existence. Papilloedema, lower cranial nerve involvement, facial paraesthesias and preoperative hydrocephalus were significantly more in cystic tumours. Total excision was achieved in 38 of the solid and 18 of the cystic tumours. VIIth nerve preservation was higher in the cystic lesions [solid 33/40 (82.5%), cystic 21/22 (95.4%)]. Myxoid degeneration, lobular growth patterns and cellular atypia were more prominent in the cystic variants. The giant vestibular schwannomas were associated with a higher incidence of cystic degeneration than has been reported for smaller tumours in literature. In cystic lesions, VIIth nerve preservation was higher due to early decompression of the lesion that facilitated in early identification of the VIIth nerve, except in patients with type C cystic tumour.
journal_name
Br J Neurosurgjournal_title
British journal of neurosurgeryauthors
Mehrotra N,Behari S,Pal L,Banerji D,Sahu RN,Jain VKdoi
10.1080/02688690802159031subject
Has Abstractpub_date
2008-08-01 00:00:00pages
550-6issue
4eissn
0268-8697issn
1360-046Xpii
902652536journal_volume
22pub_type
杂志文章abstract：:Internal fixation provides an increased immediate stability for the craniovertebral junction; however, there is no current consensus on the optimal method of occipitocervical (OC) fusion. In this report, we present 25 cases of craniovertebral instability treated with OC fusion by plates and screws instrumentation. The...
journal_title：British journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.1080/02688690400022813
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abstract：BACKGROUND:Nowadays the endoscopic endonasal approach is increasingly being used to remove craniopharyngiomas, tuberculum sellae meningiomas and other presellar and parasellar lesions and its value in anterior skull base surgery is undisputed. Herein, we assess the relative advantages, disadvantages and feasibility of ...
journal_title：British journal of neurosurgery
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abstract：:A retrospective study of the surgical management of 41 cerebellopontine angle (CPA) meningiomas was performed. All patients were treated by a single surgeon (TTK) over a 25 year period (1967-1992). There were 13 males, 28 females with a median age of 53.5 years. The median follow-up after surgery was 9 years (range 2-...
journal_title：British journal of neurosurgery
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doi：10.1080/02688699650040539
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abstract：:Objective: Vaccination therapy using tumour antigen-loaded, autologous dendritic cells (DC) is a promising therapeutic approach alongside standard treatment for glioblastoma (GBM). However, reliable diagnostic criteria regarding therapy monitoring are not established. Here, we analysed the impact of additional 18F-flu...
journal_title：British journal of neurosurgery
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abstract：:Establishing standardized methods to assess outcome is needed to measure the effectiveness of surgery in relieving symptoms and improving quality of life. We prospectively studied 203 patients undergoing primary lumbar discectomy. Data was collected before surgery, at 3 months postoperatively and at long-term follow-u...
journal_title：British journal of neurosurgery
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doi：10.1080/02688690701477310
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abstract：BACKGROUND:Nerve and muscle biopsy are common procedures often performed by junior surgical trainees. This educational review article describes the operative details of performing biopsies of muscle and nerve. Indications, pre-operative investigations and complication rates are described to aid in proper patient select...
journal_title：British journal of neurosurgery
pub_type： 杂志文章,评审
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journal_title：British journal of neurosurgery
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journal_title：British journal of neurosurgery
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doi：10.3109/02688699209002913
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journal_title：British journal of neurosurgery
pub_type： 杂志文章
doi：10.1080/0268869021000007696
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journal_title：British journal of neurosurgery
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journal_title：British journal of neurosurgery
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doi：10.3109/02688699308995051
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journal_title：British journal of neurosurgery
pub_type： 杂志文章,评审
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更新日期：1994-01-01 00:00:00
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journal_title：British journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.3109/02688697.2011.609604
更新日期：2012-04-01 00:00:00
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journal_title：British journal of neurosurgery
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doi：10.3109/02688697.2013.829554
更新日期：2014-04-01 00:00:00
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journal_title：British journal of neurosurgery
pub_type： 杂志文章
doi：10.1080/02688690600875432
更新日期：2006-08-01 00:00:00
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journal_title：British journal of neurosurgery
pub_type： 杂志文章
doi：10.1080/02688690120114183
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journal_title：British journal of neurosurgery
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doi：10.3109/02688699409101192
更新日期：1994-01-01 00:00:00
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journal_title：British journal of neurosurgery
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journal_title：British journal of neurosurgery
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更新日期：2001-02-01 00:00:00
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journal_title：British journal of neurosurgery
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abstract：:Nosrat Ollah Ameli (1913-2010) was one of the pioneers in Iranian neurosurgery. After training in England in the 1950s, Ameli returned to his country to found the Darioush Kabir Hospital, where he started the first neurosurgical ward in collaboration with Prof. E. Samiy. Here he applied his genius and innovation to de...
journal_title：British journal of neurosurgery
pub_type： 传,历史文章,杂志文章
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更新日期：2012-10-01 00:00:00
abstract：:Background: Vertebral body compression fractures are one of the most common causes of disability and morbidity, especially among the elderly population. The present study was performed in order to evaluate the effect of percutaneous balloon kyphoplasty (BKP) on patients' pain and quality of life (QOL) in Iran.Methods:...
journal_title：British journal of neurosurgery
pub_type： 杂志文章
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更新日期：2020-06-09 00:00:00
