The autoimmune basis of hypopituitarism in traumatic brain injury: fiction or reality?

Abstract:

:Post-traumatic hypopituitarism has remained as an obscured cause of worsening morbidity and mortality in head injury patients. Researchers have for decades been puzzled by the mechanism of pituitary dysfunction in these cases. Amongst other causes like direct injury, vascular injury etc, an immunological basis of hypopituitarism has been suggested in some animal studies as well as human research. In this article, we have reviewed the latest articles and compiled the evidence which suggests for or against the role of autoimmunity in post-traumatic hypopituitarism or which defines the strength to which autoimmunity has been established as a cause of head-injury induced pituitary dysfunction.

journal_name

Br J Neurosurg

authors

Harsh V,Jha S,Kumar H,Kumar A

doi

10.1080/02688697.2018.1485875

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

58-61

issue

1

eissn

0268-8697

issn

1360-046X

journal_volume

33

pub_type

杂志文章
  • Retrospective observational comparative study of Hemilaminectomy versus Laminectomy for intraspinal tumour resection; Shorter Stays, Lower Analgesic Usage and Less Kyphotic Deformity.

    abstract:INTRODUCTION:Intraspinal tumours are rare and principally managed surgically. Laminectomy, employed for access to the spinal canal, destroys the posterior tension band leading to a risk of kyphosis. Hemilaminectomy as an alternative may be less destructive, potentially reducing the risk of deformity and causing less po...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688697.2014.1003026

    authors: Millward CP,Bhagawati D,Chan HW,Bestwick J,Brecknell JE

    更新日期:2015-06-01 00:00:00

  • Audit of operating theatre time utilization in neurosurgery.

    abstract::Utilization of operating theatre time is an important issue in neurosurgery, in a National Health Service Hospital. NHS Trusts are under ever increasing pressure to meet specified 'targets' in relation to admissions and operations. We performed a retrospective audit on the utilization of neurosurgical operating theatr...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.1080/02688690400004852

    authors: Iyer RV,Likhith AM,McLean JA,Perera S,Davis CH

    更新日期:2004-08-01 00:00:00

  • Recurrent aneurysmal subarachnoid haemorrhage: incidence, timing and effects. A re-appraisal in a surgical series.

    abstract::A series of 510 patients with proven aneurysmal subarachnoid haemorrhage (SAH) is reported. The incidence of recurrent haemorrhage during the period awaiting surgery was 13.7%. There was no significant difference in incidence between good and poor grade patients. Following rebleeding there was an immediate mortality o...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688698808999657

    authors: O'Neill P,West CR,Chadwick DW,Conway M,Foy PM,Maloney P,Pickard JD,Spillane JA,Shaw MD

    更新日期:1988-01-01 00:00:00

  • The management of cerebellar abscess since the introduction of CT scanning.

    abstract::Sixteen patients with surgical infection of the posterior fossa are presented. There were 14 patients with cerebellar abscess, one patient with a solitary posterior fossa subdural empyema, and another with a combined cerebellar abscess and subdural empyema. Two of the cerebellar abscess patients also had supratentoria...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688699408995113

    authors: Brydon HL,Hardwidge C

    更新日期:1994-01-01 00:00:00

  • Persistent CSF leucocytosis associated with intrathecal gentamycin.

    abstract::A case where the administration of intrathecal gentamycin, used to treat a ventriculitis consequent upon a ventriculoperitoneal shunt infection, with a persistent elevation of the CSF leucocyte count is described. In a situation where the number of white cells in the CSF is taken to indicate resolution of infection, i...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688698909002840

    authors: Lee TK,Kerr RS,Adams CB

    更新日期:1989-01-01 00:00:00

  • Transcranial doppler ultrasonography as an early outcome forecaster following severe brain injury.

    abstract::Knowledge of post-traumatic cerebral haemodynamic disturbances might be beneficial for predicting the management outcome when measuring the basal cerebral arteries blood flow velocity by ultrasonic transcranial Doppler device immediately after severe head injury. Thirty patients who sustained severe brain injury under...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.1080/02688690601048104

    authors: Splavski B,Radanović B,Vranković D,Has B,Muzević D,Janculjak D,Legcević J

    更新日期:2006-12-01 00:00:00

  • A simplified technique for lengthening peritoneal catheters.

    abstract::Existing techniques for lengthening a peritoneal catheter require a formal laparotomy, and exploration for the catheter which is then extended by the addition of a necessary length. We describe a simplified technique which is quicker and which in co-operative patients can be done under local anaesthesia on an out-pati...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688699208995037

    authors: Mittal P,Chand M,Chhabra DK

    更新日期:1992-01-01 00:00:00

  • Cavernous malformation of the optic chiasm: case report.

    abstract::We report a 14-year-old boy with cavernous malformation of the optic chiasm. He had a 2-year history of gradually worsening visual disturbance. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a suprasellar mass, findings compatible with craniopharyngioma. The mass was biopsied and histological e...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.1080/02688690601000238

    authors: Muta D,Nishi T,Koga K,Yamashiro S,Fujioka S,Kuratsu J

    更新日期:2006-10-01 00:00:00

  • Surgical treatment of pineal cysts in non-hydrocephalic and neurologically intact patients: selection of surgical candidates and clinical outcome.

    abstract:PURPOSE:Management of patients presenting for various nonspecific complaints without clear neurological abnormalities and with normal ventricular size remains highly controversial. We intended to share our rationale for surgical treatment of patients who show symptoms of transient increase of intracranial pressure owin...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.1080/02688697.2018.1530731

    authors: Koziarski A,Podgórski A,Zieliński GM

    更新日期:2019-02-01 00:00:00

  • A device for long-term monitoring of intracranial pressure.

    abstract::A simple and inexpensive device is described for measurement of intracranial pressure over prolonged periods. ...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688698808992680

    authors: Mann KS,Yue CP

    更新日期:1988-01-01 00:00:00

  • Stereotactic mesencephalotomy for palliative care pain control: A case report, literature review and plea to rediscover this operation.

    abstract::Introduction Stereotactic mesencephalotomy is an ablative procedure which lesions the pain pathways (spinothalamic and trigeminothalamic tracts) at the midbrain level to treat medically refractory, nociceptive, contralateral pain. Sparsely reported in contemporary English language literature, this operation is at risk...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3109/02688697.2015.1133805

    authors: Ivanishvili Z,Pujara S,Honey CM,Chang S,Honey CR

    更新日期:2016-08-01 00:00:00

  • The top 50 most-cited articles on low-grade glioma: a bibliometric analysis.

    abstract:PURPOSE:There is an abundance of articles published on low-grade glioma. The aim of this study was to identify and review the 50 most-cited articles on low-grade glioma, and to perform a bibliometric analysis. METHODS:In June 2017, we performed a basic search of the Web of Science database using "low-grade glioma mana...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.1080/02688697.2018.1549314

    authors: Burak Atci I,Yilmaz H,Samanci MY

    更新日期:2019-04-01 00:00:00

  • CSF diversion in benign intracranial hypertension using a lumbo-atrial shunt.

    abstract::An obese woman with benign intracranial hypertension had been managed for several years with lumbo-peritoneal shunting. Following a bilopancreatic procedure performed for management of her obesity dense peritoneal adhesions caused repeated shunt failure. The shunt system was successfully converted to a lumbo-atrial sy...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.1080/02688690601127460

    authors: Pülhorn H,Redfern RM

    更新日期:2006-12-01 00:00:00

  • Posterior approach vertebrectomy in the thoracolumbar spine with expandable cage reconstruction: indications and techniques based on eight cases.

    abstract::We present a series of eight patients undergoing circumferential neural decompression and stabilization of the thoracolumbar spine via a single midline posterior approach, with complete vertebrectomy for a variety of indications. Four had primary tumours, two secondary tumours, one patient had tuberculosis and one had...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.1080/02688690701837273

    authors: Crocker M,James G,Ibrahim A,Thomas N,Chitnavis B

    更新日期:2008-04-01 00:00:00

  • Vertebro-PICA aneurysms: midline suboccipital approach and laminectomy of the atlas.

    abstract::Vertebro-PICA aneurysms represent a particular technical challenge because of the extremely narrow operative field and the presence of numerous vital neural and vascular structures. The lack of exposure still remains the limiting factor in most cases. During the 9-year period from January 1980 to October 1989, 8 verte...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688699008992709

    authors: Roux A,Mohr G,Hardy J

    更新日期:1990-01-01 00:00:00

  • Results of cortical resection for intractable epilepsy using intra-operative corticography without chronic intracranial recording.

    abstract::Twenty-four patients with intractable partial epilepsy underwent surgery between 1969 and 1988. Localization was by non-invasive means using scalp EEG and CT. In 12 cases the focus was temporal and in eight frontal. Craniotomy was undertaken with intraoperative electrocorticography (ECoG). Ten cases had a standard tem...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:

    authors: Davies KG,Weeks RD

    更新日期:1995-01-01 00:00:00

  • Racial differences between Maori and European New Zealanders in aneurysmal subarachnoid haemorrhage.

    abstract::Racial differences in the incidence and rate of rupture of intracranial aneurysms are well recognized. A retrospective study of racial differences between Maori and European New Zealanders presenting to the Auckland Regional Neurosurgical Unit between 1985 and 1990 was conducted. It was found that the incidence per 10...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688699309103475

    authors: Marks PV,Hope JK,Cluroe AD,Furneaux CE

    更新日期:1993-01-01 00:00:00

  • Good outcome following emergency decompressive craniectomy in a case of malignant middle cerebral artery infarction in a 14-month-old infant.

    abstract::We report the case of a 14-month-old infant presenting with unresponsiveness and seizure following thoracic surgery. Imaging showed full territory left middle cerebral artery infarct and signs of raised intracranial pressure (ICP) that required emergency decompressive craniectomy (DC). The child made a good functional...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688697.2013.776668

    authors: Grigoratos DN,Mazarakis NK,Lumsden DE,Kariyawasam S,Bhangoo R,Gordon A,Lin JP,Dlamini N

    更新日期:2013-10-01 00:00:00

  • Spinal metastatic lung adenocarcinoma with dural invasion and concomitant intradural and extradural components: a case report.

    abstract::We report the case of a metastatic lung carcinoma that had metastasized to the thoracic extradural space and penetrated the dura, resulting in a combined extra and intradural spinal tumour. To our knowledge this is the first such report of a metastatic lung adenocarcinoma demonstrating direct dural invasion. ...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.1080/02688697.2017.1324110

    authors: Raffalli-Ebezant H,Prasad A,Ray A

    更新日期:2019-04-01 00:00:00

  • A case of a cerebral syphilitic gumma developed in a few months mimicking a brain tumor in a human immunodeficiency virus-negative patient.

    abstract::Cerebral syphilitic gumma is extremely rare and easily misdiagnosed. We illustrate a case of a cerebral syphilitic gumma developed in just a few months mimicking a brain tumor in a HIV-negative patient and Treponema pallidum was detected in the cerebral syphilitic gumma. ...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688697.2016.1173190

    authors: Zhang L,Zhou Y,Chen J,Yan W,Kong Q,Chen P,Sang H

    更新日期:2017-08-01 00:00:00

  • Transsphenoidal pituitary surgery in the elderly is safe and effective.

    abstract:OBJECT:With an increasingly ageing population, the number of elderly people diagnosed with pituitary tumours continues to rise. There is a concern that with increasing age and comorbidities, there is higher anaesthetic risk, as well as peri-operative morbidity and mortality from pituitary surgery. This study aimed to a...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688697.2013.872225

    authors: Pereira EA,Plaha P,Chari A,Paranathala M,Haslam N,Rogers A,Korevaar T,Tran D,Olarinde R,Karavitaki N,Grossman AB,Cudlip SA

    更新日期:2014-10-01 00:00:00

  • The presigmoid approach for removal of tumours causing ventral compression of the brainstem. Surgical results and postoperative quality of life.

    abstract:OBJECTIVE:To assess surgical results and quality of life after removal of tumours causing ventral compression of the brainstem using the presigmoid or combined presigmoid/retrosigmoid approaches. METHODS:A review of all our patients operated on with removal of tumours causing ventral compression of the brainstem in wh...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688697.2010.525266

    authors: Frič R,Eide PK

    更新日期:2011-02-01 00:00:00

  • The treatment of childhood hydrocephalus by choroid plexus coagulation and artificial cerebrospinal fluid perfusion.

    abstract::The authors report their experience in the treatment of childhood hydrocephalus by endoscopic choroid plexus coagulation and post-operative ventricular perfusion with artificial CSF. The procedure was carried out on 23 children without mortality. In 12 cases (52%) the procedure was successful in controlling the hydroc...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688699008992706

    authors: Griffith HB,Jamjoom AB

    更新日期:1990-01-01 00:00:00

  • The role of neuroendoscopy in the management of brain tumours.

    abstract::Neuroendoscopy is increasingly used in the management of brain tumours and tumour related hydrocephalus and this study reviews the efficacy of neuroendoscopic interventions in this unit in patients with brain tumours. A series of 87 neuroendoscopic operations carried out in 77 patients with brain tumours over a 6-year...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.1080/0268869021000030276

    authors: Macarthur DC,Buxton N,Punt J,Vloeberghs M,Robertson IJ

    更新日期:2002-10-01 00:00:00

  • Prospective study evaluating post-operative central nervous system infections following cranial surgery.

    abstract:AIMS:To evaluate the efficacy of our methods for decreasing the incidence of post-operative central nervous system infections (PCNSI) and to assess the type of microbiology and risk factors associated with PCNSI. METHODS:This prospective study was performed at First Affiliated Hospital, College of Medicine, Zhejiang U...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.1080/02688697.2018.1519112

    authors: Ma YF,Wen L,Zhu Y

    更新日期:2019-02-01 00:00:00

  • The influence of barbiturates on cerebral metabolism in patients with borderline cerebrovascular reserve during intraoperative transient carotid occlusion.

    abstract::Sixty patients with borderline or frank insufficiency of their cerebrovascular reserve undergoing carotid endarterectomy were given enough short acting barbiturates, during cross clamping of the internal carotid artery, to cause EEG burst suppression. Arterial and venous concentrations of lactate were measured in bloo...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688698909002828

    authors: Wassman H,Fromm G,Nadstawek J,Bannister C,Hartmann A,Pavlidis C

    更新日期:1989-01-01 00:00:00

  • The extradural approach to lesions involving the cavernous sinus.

    abstract::We report our experience with five lesions exclusively involving the entire cavernous sinus in which an essentially extradural surgical approach was used. There were two cases of cavernous haemangioma, two cases of meningioma and one case of fungal granuloma. The dural cover of the superior orbital fissure, and mandib...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.1080/02688699746483

    authors: Goel A

    更新日期:1997-04-01 00:00:00

  • A case of intracerebral metastasis in osteosarcoma without active pulmonary metastasis.

    abstract::Intracerebral metastasis in osteosarcoma is extremely rare. A 14-year-old girl who had previously been operated upon for osteosarcoma of the femur presented with seizures and left hemiparesis. A right parietal lesion with calcification and brain oedema was found. After resection of the mass, pathology revealed an oste...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688697.2011.581771

    authors: Onodera H,Yoshida Y,Sakakibara Y,Kono T,Uchida M,Tanaka Y,Hashimoto T

    更新日期:2012-02-01 00:00:00

  • Intraventricular haematoma: management of comatose patients with valve regulated external ventricular drainage.

    abstract::Over a 2-year period, 22 consecutive comatose patients (Glasgow Coma Score of less than or equal to 8) with intraventricular haematomas were managed with prolonged external ventricular drainage via an external one-way valve regulated system. The mean duration of drainage was 12 days. The overall mortality was 23%. Acc...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3109/02688698809029600

    authors: Chan KH,Mann KS

    更新日期:1988-01-01 00:00:00

  • Stereotactic multiple arc radiotherapy. I. Vascular malformations of the brain: an analysis of the first 108 patients.

    abstract::Between March 1989 and December 1993, 101 patients with inoperable arteriovenous malformations (AVMs) and seven patients with inoperable angiographically occult malformations (AOVMs) have been treated with stereotactic multiple arc radiotherapy (SMART). All patients (excluding one patient with a brain stem AOVM) were ...

    journal_title:British journal of neurosurgery

    pub_type: 杂志文章

    doi:10.1080/02688699550041070

    authors: Sebag-Montefiore DJ,Doughty D,Biggs D,Plowman PN

    更新日期:1995-01-01 00:00:00