Abstract:
BACKGROUND:The graft site morbidity following iliac crest harvesting is significant. To overcome this, different bone substitutes like coral dowels, solvent dissolved bovine/human bone substitutes, and carbon fiber/titanium cages have been used. This study was undertaken to assess the postoperative radiological fusion rates and symptom relief in patients who had Tutobone used as an interbody spacer compared to autologous bone graft (ABG), cages, surgibone and coral dowels. METHODS:This was a retrospective, observational study. Case notes and post-operative cervical spine radiographs done at two subsequent follow-ups were reviewed. Data were derived from all Anterior Cervical Discectomy and fusion (ACDF) surgeries performed at our centre over a 10-year period for degenerative cervical spine disease. We analysed 530 patients. Exclusion criteria included incomplete notes, complex cervical surgery (both anterior and posterior fixation and vertebrectomies). Patients were divided into 3 groups, patients treated with (1) Autologous bone graft, (2) Tutobone and (3) other implants which include cages, surgibone and coral dowels. RESULTS:An analysis of 530 patients who had ACDF with either ABG (n = 328) or tutobone (n = 95) or other implants (n = 90) is presented. A significantly greater number of patients in whom autologous bone was used had more than one level surgery. The median follow-up times were 3 months and 12 months. Rates of fusion and time to fusion with bone substitutes were inferior to ABG in our series, but there was not much to choose amongst them. CONCLUSION:The use of ABG in ACDF leads to fusion in a shorter duration and greater proportion of patients, when compared to substitutes. Other implants like Tutobone (cheaper alternative), cages, etc can also be used in ACDF procedures with good efficacy with the added advantage of preventing donor site morbidity. There was no association between fusion rates and symptom relief and between use of plating and fusion.
journal_name
Br J Neurosurgjournal_title
British journal of neurosurgeryauthors
Prakash SK,Mukerji N,Nath FPdoi
10.1080/02688697.2017.1297362subject
Has Abstractpub_date
2017-06-01 00:00:00pages
340-344issue
3eissn
0268-8697issn
1360-046Xjournal_volume
31pub_type
杂志文章abstract::Spinal cord stimulation (SCS) is an established treatment modality for chronic pain, angina pectoris, and peripheral vascular disease. This study evaluates experience with SCS over a 13-year period with emphasis on surgical complications, revisions and pain relief. It took the form of a retrospective study of medical/...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690120072496
更新日期:2001-08-01 00:00:00
abstract::Choroid plexus xanthogranulomas are uncommon lesions that occur almost exclusively in adults; most of them constitute incidental autopsy findings. A case of symptomatic bilateral xanthogranulomas of choroid plexus in a 6 year-old girl with progressive visual loss is reported. Theories on the pathogenesis of this entit...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690042960
更新日期:2000-02-01 00:00:00
abstract:INTRODUCTION:Intraspinal tumours are rare and principally managed surgically. Laminectomy, employed for access to the spinal canal, destroys the posterior tension band leading to a risk of kyphosis. Hemilaminectomy as an alternative may be less destructive, potentially reducing the risk of deformity and causing less po...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2014.1003026
更新日期:2015-06-01 00:00:00
abstract::Coexistence of cerebral aneurysm and untreated craniopharyngioma is extremely rare. We present an extremely rare case of anterior cerebral artery dissecting aneurysm associated with untreated craniopharyngioma, and discuss the relationship between these two lesions. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2012.701677
更新日期:2013-02-01 00:00:00
abstract::Twenty patients with aneurysms were studied with transcranial Doppler before, during and after endovascular treatment with Guglielmi detachable coils. Catheterization of the anterior circulation decreased middle cerebral artery velocities by 15-20%. Inserting coils into the aneurysms increased pulsatility indices mode...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699550040710
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND CONTEXT:Transforaminal epidural steroid injection (TFESI) is recognised as a treatment for symptomatic lumbar disc herniation, whilst surgical decompression is generally thought to be the most effective treatment option for lumbar spinal stenosis. There is little available literature examining the effect of ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2016.1206188
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:The aim of our study is to investigate the influence of caspase-9 and tumour necrosis factor alpha (TNFα) in the grade of lumbar disc herniation. We determined the strength of different predictors such as age, gender, disc grading, caspase-9 and TNFα. METHODS:We retrospectively reviewed 84 patients who had d...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1817314
更新日期:2020-09-14 00:00:00
abstract::The aim of this randomized prospective study was to compare the efficacy of endoscopic versus standard microsurgical excision of pituitary adenomas, and to evaluate the merits and demerits of each approach. Twenty patients with a pituitary adenoma were randomly divided into two groups comprising of 10 cases each. Ten ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,随机对照试验
doi:10.1080/02688690701395447
更新日期:2007-08-01 00:00:00
abstract::We report a series of 14 patients who underwent partial or complete trigeminal nerve root section for chronic unremitting migrainous neuralgia. They had all suffered attacks with severe pain for over 18 months without remission (mean duration 5.5 years). Symptoms were refractory to extended medical intervention and ha...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699308995070
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:High-grade spondylolysthesis and spondyloptosis management have various options. There were no large series reported to support any particular treatment modality. The aim of surgery is to get solid bony fusion to get relief of instability and its symptoms as well as relief of neurological symptoms. There are ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2012.743970
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:Decompressive craniectomy is often emergently performed in an effort to reduce intracranial hypertension. After this urgent intervention, brain-injured patients often start rehabilitation programs but are left with a skull defect. Cranioplasty is often performed in these situations in order to repair this def...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2012.692838
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Nowadays the endoscopic endonasal approach is increasingly being used to remove craniopharyngiomas, tuberculum sellae meningiomas and other presellar and parasellar lesions and its value in anterior skull base surgery is undisputed. Herein, we assess the relative advantages, disadvantages and feasibility of ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2018.1480748
更新日期:2018-10-01 00:00:00
abstract::A case of primary Ewing's sarcoma involving a large portion of the petrous temporal bone in an eighteen month old child is reported. The lesion was treated by radical surgery and adjuvant chemotherapy and radiotherapy. An extremely rare age of presentation, an unusual location and an excellent response to treatment ar...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688690050004606
更新日期:2000-04-01 00:00:00
abstract:PURPOSE:The aim of the present study was to delineate preoperative factors that may predict perforator injuries following open surgery for an unruptured middle cerebral artery (MCA) aneurysm. METHODS:The authors conducted a retrospective review of 85 consecutive patients who underwent surgical clipping of 91 unrupture...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2010.535924
更新日期:2011-08-01 00:00:00
abstract::Selecting patients who will benefit from a permanent CSF diversion procedure in benign intracranial hypertension (BIH) or communicating hydrocephalus due to normal pressure hydrocephalus (NPH) has inherent problems. The percutaneous introduction of a lumbar subcutaneous shunt (LSS) under local anaesthesia facilitates ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690802007883
更新日期:2008-10-01 00:00:00
abstract::Traumatic pseudoaneurysms of the superficial temporal artery are uncommon. They present to a variety of specialities - orthopaedics, ear, nose and throat, neurosurgery, maxillofacial, plastic surgery, vascular surgery and dermatology. Experience managing these lesions is therefore limited and diluted. We present a cas...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690600777034
更新日期:2006-06-01 00:00:00
abstract:PURPOSE:The purpose of this study was to analyse all cases of spinal osteosarcoma (OS) treated in a regional bone tumour unit over the last 27 years. We were primarily interested in overall survival following tumour surgery, and if there is a difference in the survival of patients undergoing en bloc resection versus no...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.869550
更新日期:2014-08-01 00:00:00
abstract::Cortical thermal clearance was used during surgery for clipping of a giant middle cerebral artery (MCA) aneurysm. During prolonged continuous proximal MCA occlusion thermal clearance remained normal, indicating sufficient collateral blood supply. Postoperatively the patient had no neurological deficit. This monitoring...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699308995097
更新日期:1993-01-01 00:00:00
abstract::Despite advances in understanding, monitoring, and treatment, the outcome of patients with refractory brain oedema (RBE) remains poor. The concept of wide bone removal for treatment of RBE has been recognized since the nineteenth century. Bifrontal decompressive craniectomy (BDC) is performed as last resort treatment ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690802571094
更新日期:2009-02-01 00:00:00
abstract::There are two reported cases of ependymomas arising in the pituitary fossa; one in a human, the other in a horse. Both died during their stay in hospital. The case presented here is the first published case of a patient who is well 3 months after surgery. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/026886901750353764
更新日期:2001-06-01 00:00:00
abstract::This paper presents a male, immunocompetent case aged 62-year-old with cryptococcal granuloma in the basal ganglia. No cryptococcal infection occurred in other areas. The diagnosis was made by biopsy. Cryptococcal granuloma was tough and unsuitable for sterotactic biopsy. The patient died of postoperative bleeding and...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2018.1550190
更新日期:2019-01-17 00:00:00
abstract::A retrospective study was performed to evaluate the rate of infection in free and osteoplastic bone flaps after craniotomy. Two hundred and two craniotomies were performed in 98 cases of tumour, 35 cases of trauma and 69 cases of vascular disease. The overall incidence of infection was 6.4% (13 cases). The infectious ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699008993798
更新日期:1990-01-01 00:00:00
abstract::A 39-year-old female moyamoya disease patient underwent a salvage direct bypass surgery involving anastomosis of the superficial temporal artery or STA and middle cerebral artery or MCA. This report describes a rare case of moyamoya disease that was revascularized after the previous indirect bypass surgery failed to r...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2015.1071336
更新日期:2015-01-01 00:00:00
abstract:OBJECT:Animal models provide a basis for clarifying the complex pathogenesis of delayed cerebral vasospasm (DCVS) and for screening of potential therapeutic approaches. Arbitrary use of experimental parameters in current models can lead to results of uncertain relevance. The aim of this work was to identify and analyze...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688691003746274
更新日期:2010-08-01 00:00:00
abstract::The bursting pressure of samples of cerebral arteries was measured. Eighty-five samples of cerebral arteries were taken from 11 fresh cadavers. These samples were filled with saline under pressure to the point of bursting. The bursting pressures were recorded. The mean bursting pressure of all samples was 1.8 bar (137...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract:PURPOSE:Akt/mTOR/p70S6K signaling pathway promotes motor function recovery after spinal cord injury (SCI) in both neurons and astrocytes. But the role and mechanism of this pathway in oligodendrocytes during nerve repair following SCI has not been researched. This study aimed to investigate the effect and mechanism of ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1862056
更新日期:2020-12-21 00:00:00
abstract::We report a case of a giant serpentine aneurysm of the right middle cerebral artery (MCA) that was treated by total excision of the aneurysm with cerebral blood flow control management. Four years later the patient presented with a three month history of headache and angiograms showed a new aneurysm on a different bra...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699746384
更新日期:1997-06-01 00:00:00
abstract::We report a case of extensive osteomyelitis of the skull vault from a human bite. The presentation and surgical management of this unusual condition is described. The microbiological findings are comparable to known patterns of infection after human bites. Surgical management and prophylaxis after this injury are disc...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699746582
更新日期:1997-04-01 00:00:00
abstract:OBJECTIVE:To explore the changes of a series of cytokines before and after percutaneous balloon kyphoplasty (PKP) and prognostic markers for response to PKP. METHODS:From 1 January 2019 to 31 May 2019, all single-level lumbar osteoporotic vertebral compression fracture (OVCF) patients diagnosed by MRI who matched the ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1823941
更新日期:2020-10-14 00:00:00
abstract::Confusion frequently occurs in patients with gliomas for a number of reasons. One cause is a superimposed intracerebral infection. The case of a 73-year-old man who deteriorated after debulking of a high-grade glioma is described. However, he was successfully treated for Listeria monocytogenes (L. monocytogenes) diagn...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2010.535927
更新日期:2011-06-01 00:00:00