[DNA vaccines: induction of the immune response].

Abstract:

:The effectiveness of vaccines and immunization in the prevention of infectious diseases is one of the greatest successes in medicine. In recent years, with access to cutting edge genomic and proteomic technology, it is possible to accelerate the development of new and improved vaccines with better immunogenicity and safety characteristics. Since the first report almost two decades ago, where it was demonstrated that gene expression is possible by directed injection of naked DNA, DNA vaccines have been proven to induce protective immune responses against parasites, virus and bacterium in diverse animal disease models. This review aims to present an overview about DNA vaccines and the mechanisms by which immune responses are induced after immunization with plasmid DNA-encoded antigens.

journal_name

Salud Publica Mex

journal_title

Salud publica de Mexico

authors

Mota-Sánchez J

doi

10.1590/s0036-36342009000900012

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

S463-9

eissn

0036-3634

issn

1606-7916

pii

S0036-36342009000900012

journal_volume

51 Suppl 3

pub_type

杂志文章,评审
  • [Prostate cancer in Cali, Colombia, 1962-2011: incidence, mortality and survival].

    abstract:OBJECTIVE:To analyze the trend in prostate cancer survival, incidence and mortality rates in Cali, Colombia from 1962 to 2011. MATERIALS AND METHODS:Based on the Cancer Registry of Cali, Colombia and the mortality registry of the City's Public Health Secretary, incidence, mortality age-standardized rates and relative ...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Restrepo JA,Bravo LE,García-Perdomo HA,García LS,Collazos P,Carbonell J

    更新日期:2014-09-01 00:00:00

  • [Maternal overweight and obesity in Mexican school-age children. National Nutrition Survey, 1999].

    abstract:OBJECTIVE:To assess the effects of maternal overweight and obesity as risk factors for overweight and obesity in Mexican school-age children (5 to 11 years old) who participated in the National Nutrition Survey 1999 (NNS-99). MATERIAL AND METHODS:Information obtained by the NNS-99 was used to evaluate the relationship...

    journal_title:Salud publica de Mexico

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    doi:10.1590/s0036-36342005000600009

    authors: Flores M,Carrión C,Barquera S

    更新日期:2005-11-01 00:00:00

  • Iron, zinc, copper and magnesium deficiencies in Mexican adults from the National Health and Nutrition Survey 2006.

    abstract:OBJECTIVE:To describe the prevalence of serum iron and zinc deficiencies and low serum concentrations (LSC) of copper and magnesium in Mexican adults. MATERIALS AND METHODS:Blood samples from subjects (≥20 years, both genders) participating in the 2006 National Health and Nutrition Survey were used to measure the seru...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.21149/spm.v55i3.7210

    authors: Mejía-Rodríguez F,Shamah-Levy T,Villalpando S,García-Guerra A,Méndez-Gómez Humarán I

    更新日期:2013-05-01 00:00:00

  • [The epidemiology of AIDS/HIV in Mexico: from 1983 to March 1995].

    abstract::The purpose of this study is to analyze the HIV/AIDS magnitude, distribution, frequency, patterns, trends, risk factors, risk groups, estimation and evaluation of interventions in Mexico during the last twelve years. Results of a summary of statistics and results from several sources are presented including the Nation...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Valdespino-Gómez JL,García-García Mde L,del Río-Zolezzi A,Loo-Méndez E,Magis-Rodríguez C,Salcedo-Alvarez RA

    更新日期:1995-11-01 00:00:00

  • Genetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women.

    abstract:OBJECTIVE:To evaluate whether the presence of polymorphisms of peroxisome proliferator-activated receptor gamma PPARγ (Pro 1 2Ala) and PPARGC1B (Ala203Pro) modifies the association between the inorganic arsenic (iAs) methylation capacity and breast cancer (BC). MATERIALS AND METHODS:Mexican women were interviewed, and...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.21149/spm.v58i2.7791

    authors: Pineda-Belmontes CP,Hernández-Ramírez RU,Hernández-Alcaraz C,Cebrián ME,López-Carrillo L

    更新日期:2016-04-01 00:00:00

  • [Adequacy of the diet served to Tarahumara children in indigenous boarding schools of northern Mexico].

    abstract:OBJECTIVE:To assess the adequacy and variability of the diet served to Tarahumara children in indigenous boarding schools. MATERIAL AND METHODS:Records of food and drinks served for meals, weighed daily, were obtained from Monday through Friday for 10 consecutive weeks in two selected boarding schools. Nutrient intake...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.1590/s0036-36342010000100005

    authors: Monárrez-Espino J,Béjar-Lío GI,Vázquez-Mendoza G

    更新日期:2010-01-01 00:00:00

  • [Universal access, six years results in the Mexico City HIV/AIDS Program].

    abstract:OBJECTIVE:To analyze the results of the Free Antiretroviral Medication Program of the Mexico City HIV/AIDS Program among the affected population in Mexico City. MATERIAL AND METHODS:A retrospective analysis was conducted of medical attention, antiretroviral treatment and specialized laboratory results data from 2001 t...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.1590/s0036-36342009000100007

    authors: Soler Claudín C

    更新日期:2009-01-01 00:00:00

  • Antimicrobial resistance and antibiotic consumption in Mexican hospitals.

    abstract:OBJECTIVE:To establish the current situation of antimicrobial resistance and antibiotic consumption in Mexican hospitals. MATERIALS AND METHODS:Antimicrobial susceptibility data from blood and urine isolates were collected. Defined daily dose (DDD) of antibiotic consumption/100 occupied beds (OBD) was calculated. RES...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章,多中心研究

    doi:10.21149/10543

    authors: Miranda-Novales MG,Flores-Moreno K,López-Vidal Y,Rodríguez-Álvarez M,Solórzano-Santos F,Soto-Hernández JL,Ponce de León-Rosales S,UNCAR Network*.

    更新日期:2020-01-01 00:00:00

  • [An application of the strategy results cycle to HIV/AIDS strategic planning in Latin America].

    abstract:OBJECTIVE:To describe the Strategy Results Cycle (SRC), a model that approaches planning as an ongoing cycle of seven phases that continually responds and adapts to existing evidence. MATERIALS AND METHODS:Reliable sources were used for the preparation of databases and expenditure-costing data for resources needs anal...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Rodríguez-García R,Rosenberg H

    更新日期:2013-07-01 00:00:00

  • [Validation of a questionnaire for measurement of beliefs about the climacteric].

    abstract:OBJECTIVE:To design an instrument for measuring beliefs about the social, psychological, and physiological consequences of women's climacteric stage. MATERIAL AND METHODS:The study included 340 women affiliated to Instituto de Seguridad y Servicios Sociales para los Trabajadores del Estado (Institute for Social Servic...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Chávez-Ayala R,Andrade-Palos P,Rivera-Rivera L

    更新日期:2002-09-01 00:00:00

  • [Evolution of air pollution and impact on control programs in 3 megacities in Latin America].

    abstract::The present work discusses the problems of atmospheric pollution of three Megacities of Latin America (Mexico City, Sao Paulo and Santiago). The environmental pollution control programs implemented by the Government are revised and the evolution of pollution levels during the period of 1988-1995 at Santiago de Chile a...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Lacasaña-Navarro M,Aguilar-Garduño C,Romieu I

    更新日期:1999-05-01 00:00:00

  • [Concept and practice of international health in the Takemi program].

    abstract::The Takemi Program in International Health was established at the Harvard School of Public Health in 1983 as a research and advanced training program for midcareer health professionals concerned with the allocation of resources for health, especially in developing countries. This essay describes the origins of the Tak...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Reich MR

    更新日期:1991-07-01 00:00:00

  • [A first analysis of research on social determinants of health in Mexico: 2005-2012].

    abstract:OBJECTIVE:To examine the research on social determinants of health (SDH) produced in Mexico during the period 2005-2012, based on the characterization of the national health research system and the scientific production on this topic. MATERIALS AND METHODS:Two-stage analyses: Review of Mexican documents and official s...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Salgado-de Snyder VN,Guerra-y Guerra G

    更新日期:2014-07-01 00:00:00

  • [Barriers and facilitators to antenatal care in adolescents: results of a qualitative study in Chile].

    abstract:OBJECTIVE:Analyze barriers and facilitators of access to prenatal care in pregnant urban adolescents between 15-19 years of age in Santiago, Chile. MATERIALS AND METHODS:Qualitative study based on grounded theory with 17 adolescent mothers. Eleven semi-structured interviews and one focus group were conducted. RESULT:...

    journal_title:Salud publica de Mexico

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    doi:

    authors: Poffald L,Hirmas M,Aguilera X,Vega J,González MJ,Sanhueza G

    更新日期:2013-12-01 00:00:00

  • [Hypertension in Mexican adults: prevalence, diagnosis and type of treatment. Ensanut MC 2016.]

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    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.21149/8813

    authors: Campos-Nonato I,Hernández-Barrera L,Pedroza-Tobías A,Medina C,Barquera S

    更新日期:2018-05-01 00:00:00

  • [Mortality as a result of accidental and intentional injuries in the Federal District from 1970 to 1986].

    abstract::This article presents the results of a retrospective analysis of unintentional and intentional injury mortality in México City for the period 1970-1986. The mortality rates and trends were obtained out of 73,197 registered deaths, (according to the 9th revision of the International Disease Classification). Deaths due ...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Híjar-Medina MC

    更新日期:1990-07-01 00:00:00

  • [Smoking tobacco in Costa Rica: susceptibility, consumption and dependence].

    abstract:Objective::To identify factors associated with susceptibility, tobacco use and addiction in young people from 13 to 15 years of age, to determine conditions of risk and identify possible correlates to the development of public policies on smoking in Costa Rica. Materials and methods::Information available from the fou...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.21149/7765

    authors: Fonseca-Chaves S,Méndez-Muñoz J,Bejarano-Orozco J,Guerrero-López CM,Reynales-Shigematsu LM

    更新日期:2017-01-01 00:00:00

  • [A decade of lead monitoring in schoolchildren in the metropolitan area of Monterrey NL, Mexico].

    abstract:OBJECTIVE:To establish the blood lead concentration and associated risk factors in schoolchildren during 1998 and 2008. MATERIALS AND METHODS:A blood lead screening was conducted in schoolchildren of 6-12 years of age, enrolled in 17 elementary schools of the metropolitan area of Monterrey, México, during 1998 and 200...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Santos-Guzmán J,Madrigal-Ávila C,Hernández-Hernández JA,Mejía-Velázquez G,Eraña-Rojas IE,Elizondo-Montemayor L,Villela L

    更新日期:2014-11-01 00:00:00

  • The urgent need to change the current medical approach on tobacco cessation in Latin America.

    abstract::Despite of the accumulation of scientific evidence confirming the health consequences of smoking and the new paradigm of smoking as a disease where nicotine is the drug that modifies the functional and morphological characteristics of the brain in dependent smokers, tobacco smoking continues as an important public hea...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.1590/s0036-36342010000800035

    authors: Ponciano-Rodríguez G

    更新日期:2010-01-01 00:00:00

  • [The health system of Dominican Republic].

    abstract::This paper describes the health conditions in Dominican Republic and the characteristics of the Dominican health system, including its structure and coverage, its financial sources, the health expenditure, the physical, material and human resources available, the stewardship functions developed by the Ministry of Publ...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章,评审

    doi:

    authors: Rathe M,Moliné A

    更新日期:2011-01-01 00:00:00

  • Prospects for controlling cervical cancer at the turn of the century.

    abstract::Cervical cancer morbidity and mortality have decreased substantially during the last 50 years mostly due to successful organized or opportunistic screening with Pap cytology in high and middle income countries. In many low income countries Pap cytology screening is yet to be effectively implemented or has failed to re...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章,评审

    doi:10.1590/s0036-36342003000900011

    authors: Franco EL,Duarte-Franco E,Ferenczy A

    更新日期:2003-01-01 00:00:00

  • [Fluorosis in primary dentition in a region with endemic water fluoride].

    abstract:OBJECTIVE:The aim of the present study was to estimate the prevalence of dental fluorosis in primary dentition of a San Luis Potosi children population, and its association to fluoride concentration in drinking water and urine. An additional objective was, to develop, validate, and test a specific index for dental fluo...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Loyola-Rodríguez JP,Pozos-Guillén AJ,Hernández-Guerrero JC,Hernández-Sierra JF

    更新日期:2000-05-01 00:00:00

  • [Decentralization of health services in Mexico in the 80's].

    abstract::The objective of this article is to review the decentralization process that took place in the 1980s. First, some principles in relation to this topic are presented. Next, the legal foundations and the agreements which were established for Federation-states coordination are outlined, as well as basic points related to...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Soberón-Acevedo G,Martínez-Narváez G

    更新日期:1996-09-01 00:00:00

  • Intellectual disability: definition, etiological factors, classification, diagnosis, treatment and prognosis.

    abstract:UNLABELLED:ETIOLOGY AND CLASSIFICATION: Causal factors related with cognitive disability are multiples and can be classified as follows: Genetic, acquired (congenital and developmental), environmental and sociocultural. Likewise, in relation to the classification, cognitive disability has as a common denominator a subn...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章,评审

    doi:10.1590/s0036-36342008000800005

    authors: Katz G,Lazcano-Ponce E

    更新日期:2008-01-01 00:00:00

  • [Quantification of lead, cadmium and chromium by sialochemistry].

    abstract:OBJECTIVE:To determine the concentration of lead (Pb), cadmium (Cd), and chromium (Cr) and establish the possible association of these heavy metals with some sociodemographic factors. MATERIAL AND METHODS:A representative sample of one hundred dental students from the National Autonomous University of Mexico living in...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: González M,Banderas JA,Raya C,Báez A,Belmont R

    更新日期:1997-05-01 00:00:00

  • [Use of heart rate variability as a marker of cardiovascular effects associated with air pollution].

    abstract::Epidemiological studies have shown the association between atmospheric pollutants and increase in mortality due to cardiovascular causes, especially in patients with previous cardio-respiratory diseases. However, the pathophysiological mechanisms by which these events take place have not been elucidated. One of the pr...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章,评审

    doi:10.1590/s0036-36342006000400010

    authors: Riojas-Rodríguez H,Holguin F,González-Hermosillo A,Romieu I

    更新日期:2006-07-01 00:00:00

  • [Reflections on smoking intervention opportunities in Latin America].

    abstract::The tobacco epidemic is a huge public health problem affecting all Latin American countries. These countries have the characteristic of a wide base of the pyramidal population structure, with many young people who have been natural targets for the tobacco industry. Therefore in this region there is an urgent need to e...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.1590/s0036-36342010000800025

    authors: Zabert G,Chatkin JM,Ponciano-Rodríguez G

    更新日期:2010-01-01 00:00:00

  • [Correcting for misclassified HIV/aids deaths in Mexico: Retrospective analysis, 1983-2012].

    abstract:OBJECTIVE:To identify and reassign misclassified AIDS deaths in Mexico, reconstructing the time series of mortality from 1983 to 2012, by state, sex, age, and affiliation to social security. MATERIALS AND METHODS:15.5 million deaths from 1979 to 2012 were analyzed. The HIV-AIDS mortality correction was done in three p...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Cahuana-Hurtado L,Chilian-Herrera O,Bautista-Arredondo S,Contreras-Loya D,Franco-Marina F,González-Vilchis JJ,Lozano R

    更新日期:2015-01-01 00:00:00

  • [Mortality trends in cancer attributable to tobacco in Mexico].

    abstract:OBJECTIVE:To describe the mortality trends of cancer attributable to tobacco smoking, particularly lung cancer, for the 1980-1997 period in Mexico. MATERIAL AND METHODS:Mortality trends were analyzed for each type of cancer associated to tobacco smoking, according to the International Classification of Diseases (ICD)....

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Tovar-Guzmán VJ,Barquera S,López-Antuñano FJ

    更新日期:2002-01-01 00:00:00

  • [Risk indicators for the problematic consumption of drugs among young students. Applications in research and primary care at school].

    abstract::This article analyzes 33 risk indicators about problematic drugs use, based in epidemiological studies in representative student samples, carried out in Mexico since 1975. The indicators are distributed among the variation sources proposed by the classic epidemiological model (environment-agent-host), and are aimed to...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Castro-Sariñana ME

    更新日期:1990-05-01 00:00:00