Abstract:
:The effectiveness of vaccines and immunization in the prevention of infectious diseases is one of the greatest successes in medicine. In recent years, with access to cutting edge genomic and proteomic technology, it is possible to accelerate the development of new and improved vaccines with better immunogenicity and safety characteristics. Since the first report almost two decades ago, where it was demonstrated that gene expression is possible by directed injection of naked DNA, DNA vaccines have been proven to induce protective immune responses against parasites, virus and bacterium in diverse animal disease models. This review aims to present an overview about DNA vaccines and the mechanisms by which immune responses are induced after immunization with plasmid DNA-encoded antigens.
journal_name
Salud Publica Mexjournal_title
Salud publica de Mexicoauthors
Mota-Sánchez Jdoi
10.1590/s0036-36342009000900012subject
Has Abstractpub_date
2009-01-01 00:00:00pages
S463-9eissn
0036-3634issn
1606-7916pii
S0036-36342009000900012journal_volume
51 Suppl 3pub_type
杂志文章,评审abstract:OBJECTIVE:To analyze the trend in prostate cancer survival, incidence and mortality rates in Cali, Colombia from 1962 to 2011. MATERIALS AND METHODS:Based on the Cancer Registry of Cali, Colombia and the mortality registry of the City's Public Health Secretary, incidence, mortality age-standardized rates and relative ...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:To assess the effects of maternal overweight and obesity as risk factors for overweight and obesity in Mexican school-age children (5 to 11 years old) who participated in the National Nutrition Survey 1999 (NNS-99). MATERIAL AND METHODS:Information obtained by the NNS-99 was used to evaluate the relationship...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.1590/s0036-36342005000600009
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:To describe the prevalence of serum iron and zinc deficiencies and low serum concentrations (LSC) of copper and magnesium in Mexican adults. MATERIALS AND METHODS:Blood samples from subjects (≥20 years, both genders) participating in the 2006 National Health and Nutrition Survey were used to measure the seru...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.21149/spm.v55i3.7210
更新日期:2013-05-01 00:00:00
abstract::The purpose of this study is to analyze the HIV/AIDS magnitude, distribution, frequency, patterns, trends, risk factors, risk groups, estimation and evaluation of interventions in Mexico during the last twelve years. Results of a summary of statistics and results from several sources are presented including the Nation...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVE:To evaluate whether the presence of polymorphisms of peroxisome proliferator-activated receptor gamma PPARγ (Pro 1 2Ala) and PPARGC1B (Ala203Pro) modifies the association between the inorganic arsenic (iAs) methylation capacity and breast cancer (BC). MATERIALS AND METHODS:Mexican women were interviewed, and...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.21149/spm.v58i2.7791
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:To assess the adequacy and variability of the diet served to Tarahumara children in indigenous boarding schools. MATERIAL AND METHODS:Records of food and drinks served for meals, weighed daily, were obtained from Monday through Friday for 10 consecutive weeks in two selected boarding schools. Nutrient intake...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.1590/s0036-36342010000100005
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To analyze the results of the Free Antiretroviral Medication Program of the Mexico City HIV/AIDS Program among the affected population in Mexico City. MATERIAL AND METHODS:A retrospective analysis was conducted of medical attention, antiretroviral treatment and specialized laboratory results data from 2001 t...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.1590/s0036-36342009000100007
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:To establish the current situation of antimicrobial resistance and antibiotic consumption in Mexican hospitals. MATERIALS AND METHODS:Antimicrobial susceptibility data from blood and urine isolates were collected. Defined daily dose (DDD) of antibiotic consumption/100 occupied beds (OBD) was calculated. RES...
journal_title:Salud publica de Mexico
pub_type: 杂志文章,多中心研究
doi:10.21149/10543
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To describe the Strategy Results Cycle (SRC), a model that approaches planning as an ongoing cycle of seven phases that continually responds and adapts to existing evidence. MATERIALS AND METHODS:Reliable sources were used for the preparation of databases and expenditure-costing data for resources needs anal...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:To design an instrument for measuring beliefs about the social, psychological, and physiological consequences of women's climacteric stage. MATERIAL AND METHODS:The study included 340 women affiliated to Instituto de Seguridad y Servicios Sociales para los Trabajadores del Estado (Institute for Social Servic...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract::The present work discusses the problems of atmospheric pollution of three Megacities of Latin America (Mexico City, Sao Paulo and Santiago). The environmental pollution control programs implemented by the Government are revised and the evolution of pollution levels during the period of 1988-1995 at Santiago de Chile a...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00
abstract::The Takemi Program in International Health was established at the Harvard School of Public Health in 1983 as a research and advanced training program for midcareer health professionals concerned with the allocation of resources for health, especially in developing countries. This essay describes the origins of the Tak...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:To examine the research on social determinants of health (SDH) produced in Mexico during the period 2005-2012, based on the characterization of the national health research system and the scientific production on this topic. MATERIALS AND METHODS:Two-stage analyses: Review of Mexican documents and official s...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:Analyze barriers and facilitators of access to prenatal care in pregnant urban adolescents between 15-19 years of age in Santiago, Chile. MATERIALS AND METHODS:Qualitative study based on grounded theory with 17 adolescent mothers. Eleven semi-structured interviews and one focus group were conducted. RESULT:...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To describe the prevalence, awareness and proportion of adults with an adequate control of hypertension. MATERIALS AND METHODS:Blood pressure was measured at 8 352 adults who participated in the Ensanut MC 2016. The adults who reported having diagnosis of hypertension or had systolic blood pressure values (T...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.21149/8813
更新日期:2018-05-01 00:00:00
abstract::This article presents the results of a retrospective analysis of unintentional and intentional injury mortality in México City for the period 1970-1986. The mortality rates and trends were obtained out of 73,197 registered deaths, (according to the 9th revision of the International Disease Classification). Deaths due ...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract:Objective::To identify factors associated with susceptibility, tobacco use and addiction in young people from 13 to 15 years of age, to determine conditions of risk and identify possible correlates to the development of public policies on smoking in Costa Rica. Materials and methods::Information available from the fou...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.21149/7765
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To establish the blood lead concentration and associated risk factors in schoolchildren during 1998 and 2008. MATERIALS AND METHODS:A blood lead screening was conducted in schoolchildren of 6-12 years of age, enrolled in 17 elementary schools of the metropolitan area of Monterrey, México, during 1998 and 200...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2014-11-01 00:00:00
abstract::Despite of the accumulation of scientific evidence confirming the health consequences of smoking and the new paradigm of smoking as a disease where nicotine is the drug that modifies the functional and morphological characteristics of the brain in dependent smokers, tobacco smoking continues as an important public hea...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.1590/s0036-36342010000800035
更新日期:2010-01-01 00:00:00
abstract::This paper describes the health conditions in Dominican Republic and the characteristics of the Dominican health system, including its structure and coverage, its financial sources, the health expenditure, the physical, material and human resources available, the stewardship functions developed by the Ministry of Publ...
journal_title:Salud publica de Mexico
pub_type: 杂志文章,评审
doi:
更新日期:2011-01-01 00:00:00
abstract::Cervical cancer morbidity and mortality have decreased substantially during the last 50 years mostly due to successful organized or opportunistic screening with Pap cytology in high and middle income countries. In many low income countries Pap cytology screening is yet to be effectively implemented or has failed to re...
journal_title:Salud publica de Mexico
pub_type: 杂志文章,评审
doi:10.1590/s0036-36342003000900011
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to estimate the prevalence of dental fluorosis in primary dentition of a San Luis Potosi children population, and its association to fluoride concentration in drinking water and urine. An additional objective was, to develop, validate, and test a specific index for dental fluo...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2000-05-01 00:00:00
abstract::The objective of this article is to review the decentralization process that took place in the 1980s. First, some principles in relation to this topic are presented. Next, the legal foundations and the agreements which were established for Federation-states coordination are outlined, as well as basic points related to...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:UNLABELLED:ETIOLOGY AND CLASSIFICATION: Causal factors related with cognitive disability are multiples and can be classified as follows: Genetic, acquired (congenital and developmental), environmental and sociocultural. Likewise, in relation to the classification, cognitive disability has as a common denominator a subn...
journal_title:Salud publica de Mexico
pub_type: 杂志文章,评审
doi:10.1590/s0036-36342008000800005
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To determine the concentration of lead (Pb), cadmium (Cd), and chromium (Cr) and establish the possible association of these heavy metals with some sociodemographic factors. MATERIAL AND METHODS:A representative sample of one hundred dental students from the National Autonomous University of Mexico living in...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract::Epidemiological studies have shown the association between atmospheric pollutants and increase in mortality due to cardiovascular causes, especially in patients with previous cardio-respiratory diseases. However, the pathophysiological mechanisms by which these events take place have not been elucidated. One of the pr...
journal_title:Salud publica de Mexico
pub_type: 杂志文章,评审
doi:10.1590/s0036-36342006000400010
更新日期:2006-07-01 00:00:00
abstract::The tobacco epidemic is a huge public health problem affecting all Latin American countries. These countries have the characteristic of a wide base of the pyramidal population structure, with many young people who have been natural targets for the tobacco industry. Therefore in this region there is an urgent need to e...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.1590/s0036-36342010000800025
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To identify and reassign misclassified AIDS deaths in Mexico, reconstructing the time series of mortality from 1983 to 2012, by state, sex, age, and affiliation to social security. MATERIALS AND METHODS:15.5 million deaths from 1979 to 2012 were analyzed. The HIV-AIDS mortality correction was done in three p...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To describe the mortality trends of cancer attributable to tobacco smoking, particularly lung cancer, for the 1980-1997 period in Mexico. MATERIAL AND METHODS:Mortality trends were analyzed for each type of cancer associated to tobacco smoking, according to the International Classification of Diseases (ICD)....
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::This article analyzes 33 risk indicators about problematic drugs use, based in epidemiological studies in representative student samples, carried out in Mexico since 1975. The indicators are distributed among the variation sources proposed by the classic epidemiological model (environment-agent-host), and are aimed to...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1990-05-01 00:00:00