Abstract:
OBJECTIVE:To evaluate whether the presence of polymorphisms of peroxisome proliferator-activated receptor gamma PPARγ (Pro 1 2Ala) and PPARGC1B (Ala203Pro) modifies the association between the inorganic arsenic (iAs) methylation capacity and breast cancer (BC). MATERIALS AND METHODS:Mexican women were interviewed, and blood and urine samples were collected from them (cases/controls= 197/220). The concentration of urinary arsenic species and the polymorphisms of interest were determined by high-performance liquid chromatography with inductively coupled plasma mass spectrometry (HPLC-ICP-MS) and polymerase chain reaction (PCR), respectively. RESULTS:In women with a high %MMA (urinary monomethyl arsenic) and high primary methylation ratio (PM = MMA/iAs), the risk of BC was increased (odds ratio [OR]%MMA T3 vs.T1= 3.60: 95% confidence interval [CI] 2.02-6.41, ORPMI T3 vs.T1= 3.47: 95%CI 1.95-6.17), which was maintained after adjusting for polymorphisms. No significant interactions were observed between the polymorphisms and the arsenic variables on the risk of BC. CONCLUSION:Pro 12Ala and Ala203Pro polymorphisms did not modify the association between the iAs methylation capacity and BC.
journal_name
Salud Publica Mexjournal_title
Salud publica de Mexicoauthors
Pineda-Belmontes CP,Hernández-Ramírez RU,Hernández-Alcaraz C,Cebrián ME,López-Carrillo Ldoi
10.21149/spm.v58i2.7791subject
Has Abstractpub_date
2016-04-01 00:00:00pages
220-7issue
2eissn
0036-3634issn
1606-7916pii
S0036-36342016000200220journal_volume
58pub_type
杂志文章abstract:OBJECTIVE:To discover the prevalence of antibodies against denguevirus and leptospira. MATERIAL AND METHODS:A cross-sectional study was carried out in 500 inhabitants of Veracruz, Mexico through household sampling, administration of a questionnaire and collection of blood samples.The presence of IgG antibodies was det...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.1590/s0036-36342006000300006
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to estimate the prevalence of dental fluorosis in primary dentition of a San Luis Potosi children population, and its association to fluoride concentration in drinking water and urine. An additional objective was, to develop, validate, and test a specific index for dental fluo...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2000-05-01 00:00:00
abstract::This document summarizes the most relevant epidemiologic characteristics of infant and child mortality in Latin America. The gap in infant mortality rates between Latin America and the developed countries is wide and appears to be increasing. In the developed countries, 980 of each 1000 infants survive to the age of...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1988-05-01 00:00:00
abstract:OBJECTIVE:Analyze the impact of a mixed regime of infectious and chronic conditions among older adults in Mexico on their health progression. MATERIALS AND METHODS:A total of 12 207 adults from the Mexican Health and Aging Study were included. Logistic regression analyses were conducted to assess the relationship betw...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.1590/s0036-36342012000500005
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:The objectives are obtain the internal consistency, validity and factorial structure of the Self-Efficacy for AIDS scale, which was developed in American population by Kasen, Vaughan and Walter (1992) and adapted in mexican samples for López and Padilla (1999). INSTRUMENTS:It is employed the Self-efficacy t...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract::This work is a review of the philosophical analysis surrounding the concept of "humanism" and what it means to be a human being, in relationship to daily life, education and medicine. The authors establish a direct relationship between humanism and bioethics as they relate to the new trends acquired through the develo...
journal_title:Salud publica de Mexico
pub_type: 杂志文章,评审
doi:
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVES:To evaluate equity in access by comparing geographic, economic, and organizational barriers as well as authorization obstacles that women encounter depending on their affiliation with the social security health system. MATERIAL AND METHODS:A retrospective survey was conducted among women undergoing breast c...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.1590/s0036-36342009000800015
更新日期:2009-01-01 00:00:00
abstract::In 1987 John Rowe introduced the concept of Successful Aging. This is a new point of view, and its appearance has been followed by a growing amount of literature and research on the subject. The author reviews the concept of Successful Aging and some of the results of his experimental work. The growing numbers of peop...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract::Violence against women by partners (VAWP) has been systematically studied in Mexico in the past 15 years. The aim of this paper is to reflect on the contributions on this topic in Mexico. The discussion focuses on the magnitude of this phenomenon, stressing its theoretical, methodological, and technical implications; ...
journal_title:Salud publica de Mexico
pub_type: 杂志文章,评审
doi:10.1590/s0036-36342006000800012
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To analyze the current knowledge of pathogen-insect interactions amenable for the design of molecular-based control strategies of vector-borne diseases. MATERIALS AND METHODS:We examined malaria, dengue, and Chagas disease pathogens and insect molecules that participate in interactions during their vectors i...
journal_title:Salud publica de Mexico
pub_type: 杂志文章,评审
doi:10.21149/8140
更新日期:2018-01-01 00:00:00
abstract::The right to health and its operational form, as an organized social response to health: the right to health protection, are the mainstay for the global push towards universal health coverage. The path to achieve this goal is particular to each country and relates to the baseline and specific context in relation to wh...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2015-03-01 00:00:00
abstract::The effectiveness of vaccines and immunization in the prevention of infectious diseases is one of the greatest successes in medicine. In recent years, with access to cutting edge genomic and proteomic technology, it is possible to accelerate the development of new and improved vaccines with better immunogenicity and s...
journal_title:Salud publica de Mexico
pub_type: 杂志文章,评审
doi:10.1590/s0036-36342009000900012
更新日期:2009-01-01 00:00:00
abstract::Data from a National Nutrition Survey conducted in 1988 in a probability sample of 13,236 households and 17,426 children under five, representative at the national level and for four regions (North, Center, South, and Mexico City), were analyzed. Risks for wasting and stunting and odds ratios were obtained by region, ...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract::Institutions such as World Health Organization and United Nations have considered the necessity to establish programs to control and preserve our environment. From the beginning, industrial development has polluted the air, water and soil, in some cases irreversibly affecting the ecosystems. Rampant use of natural res...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
abstract::Cervical cancer is a major public health problem, as it is the second most common cancer in women world-wide after breast cancer. About 80% of the half a million cases estimated to occur annually in the world, occur in developing countries. The epidemiological evidence linking human papillomavirus (HPV) to cervical ca...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.1590/s0036-36341997000400005
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:To identify and reassign misclassified AIDS deaths in Mexico, reconstructing the time series of mortality from 1983 to 2012, by state, sex, age, and affiliation to social security. MATERIALS AND METHODS:15.5 million deaths from 1979 to 2012 were analyzed. The HIV-AIDS mortality correction was done in three p...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:2015-01-01 00:00:00
abstract::In this report the organization and performance of the IMSS-Solidaridad Program of Mexico is described. This program is managed by the Mexican Institute for Social Security, which services 10.5 million inhabitants of the rural underserved areas, with federal government resources in 18 states. This study compares the s...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract::The main points of encounter and/or differences between two sociomedical analytical models are discussed. Both models have substantially contributed to an integrated perspective on public health. Discussion is focused on the conceptual construction of social processes and the contribution of these social processes on ...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract::A geriatric evaluation was carried out in a group of 37 elderly nursing home residents. A complete history and physical examination was performed in all the patients. We identified 185 new medical problems in the patients, 40.7 per cent of whom were rehabilitation candidates. A functional status evaluation on daily ac...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract:OBJECTIVE:This study aimed to search the literature for intervention programs in primary care with a multiprofes-sional character, specifically directed at the robust elderly, and with viable and cost-effective interventions. MATERIALS AND METHODS:The search strategies were applied in Cochrane, Lilacs, Pubmed, Scopus,...
journal_title:Salud publica de Mexico
pub_type: 杂志文章,评审
doi:10.21149/spm.v57i3.7566
更新日期:2015-05-01 00:00:00
abstract::Cervical cancer morbidity and mortality have decreased substantially during the last 50 years mostly due to successful organized or opportunistic screening with Pap cytology in high and middle income countries. In many low income countries Pap cytology screening is yet to be effectively implemented or has failed to re...
journal_title:Salud publica de Mexico
pub_type: 杂志文章,评审
doi:10.1590/s0036-36342003000900011
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To determine the concentration of lead (Pb), cadmium (Cd), and chromium (Cr) and establish the possible association of these heavy metals with some sociodemographic factors. MATERIAL AND METHODS:A representative sample of one hundred dental students from the National Autonomous University of Mexico living in...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract::Four experiences in health education in communities located in the state of Lara in Venezuela were analyzed from a sociopsychological perspective. Under a qualitative approach, the information was obtained from three sources: documentary analysis of didactic material; participant observation in workshops, and intervie...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVE:To analyze mortality and incidence for 28 cancers by deprivation status, age and sex from 1990 to 2013. MATERIALS AND METHODS:The data and methodological approaches provided by the Global Burden of Disease (GBD 2013) were used. RESULTS:Trends from 1990 to 2013 show important changes in cancer epidemiology i...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.21149/spm.v58i2.7780
更新日期:2016-04-01 00:00:00
abstract::The Global Smokefree Partnership has recently prepared a map of smokefree campaigns and policies around the world. It focuses primarily on countries that are parties to the WHO Framework Convention on Tobacco Control, but other countries were included. The smokefree status of 172 countries was mapped. Of these countri...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.1590/s0036-36342008000900006
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:Understand what Mexican key stakeholders think about the judicialization of the right to health in Mexico. MATERIALS AND METHODS:30 semi-structured interviews were conducted at different settings in Mexico City with representatives of the judiciary, legislative power, Health Sector (HS), pharmaceutical indus...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.21149/10491
更新日期:2020-09-23 00:00:00
abstract::The epithelial ovarian cancer (EOC) has been underdiagnosed because it does not have a specific clinical presentation, and the signs and symptoms are similar to the irritable bowel syndrome and pelvic inflammatory disease. EOC is less common than breast and cervical cancer, but it is more lethal. On the whole, EOC has...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.21149/spm.v58i2.7801
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:To describe the patterns of antimicrobial resistance of organisms isolated from urine cultures at a teaching oncological hospital for adult patients. MATERIAL AND METHODS:All strains obtained from urine cultures from 1998 to 2005 were included. Mean susceptibilities were obtained for each antimicrobial teste...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.1590/s0036-36342007000500003
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence and risk factors for oral high-risk human papillomavirus (HR-HPV) infec- tion in human immunodeficiency virus(HIV)-infected men. MATERIALS AND METHODS:Consecutive male outpatients with HIV-infection were enrolled. Demographic and behav- ioral risk data were obtained. Anal swabs an...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.21149/9834
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:To analyze the mortality trend of lung cancer (LC) in Mexico, according to the municipality marginalization index (MMI) by age group and sex, during the period 1998-2016. MATERIALS AND METHODS:The information on mortality, population and MMI was obtained from the National Institute of Statistics and Geograph...
journal_title:Salud publica de Mexico
pub_type: 杂志文章
doi:10.21149/10083
更新日期:2019-05-01 00:00:00