Mitral valve repair versus replacement.

Abstract:

:When considering all the major series comparing the early and late results of mitral valve repair versus prosthetic or bioprosthetic mitral valve replacement, the operative mortality rate is slightly lower for patients undergoing valve reconstruction. Late survival is also superior after valve repair. Although these modest differences may be related to patient selection bias, a lower rate of thromboembolic and endocarditis-related complications and improved LV function remain as rather compelling factors favoring valve repair. The durability of valve repair is comparable to valve replacement in terms of reoperation rate, except in cases of rheumatic valve abnormality (in which reoperation rates are higher after valvuloplasty). Definitive, objective evidence favoring mitral valve repair is lacking given the short period of followup in all studies and absence of controlled, randomized clinical trials. The success of mitral valve reconstruction relies heavily on the experience and technical expertise of the surgeon. The wide variability in observed survival rates, however, is unlikely to be due to differences in surgical skill between experienced groups; it more likely represents the results of differing criteria for mitral valve repair, various followup intervals, and comparisons between distinctly different cohorts. Although a prospective randomized trial would be ideal to compare the results of mitral valve reconstruction versus mitral valve replacement for patients with mitral valve regurgitation, it is unlikely and unrealistic that such a study will ever be conducted. The universal applicability of the results of such a study would also be dubious, given the widely varying extent of surgical expertise with mitral valve repair. Furthermore, not all types of mitral regurgitation are amendable to reconstruction short of using patch techniques (usually autologous pericardium treated with glutaraldehyde) or resorting to artificial chordae (e.g., extensive leaflet destruction from rheumatic changes or infective endocarditis, and substantial anterior leaflet redundancy). In cases in which mitral valve replacement is necessary, preservation of the mitral subvalvular apparatus promises to be an important concept to preserve optimal systolic LV function postoperatively.

journal_name

Cardiol Clin

journal_title

Cardiology clinics

authors

Yun KL,Miller DC

subject

Has Abstract

pub_date

1991-05-01 00:00:00

pages

315-27

issue

2

eissn

0733-8651

issn

1558-2264

journal_volume

9

pub_type

杂志文章,评审
  • How should clinicians interpret clinical trials?

    abstract::Given the rapid evolution of cardiovascular medicine, clinicians must sift through an enormous array of information about new therapies in order to determine how best to treat patients with ischemic heart disease. They should first consider the evidence from randomized clinical trials, because these trials eliminate b...

    journal_title:Cardiology clinics

    pub_type: 杂志文章

    doi:

    authors: Califf RM

    更新日期:1995-08-01 00:00:00

  • High blood pressure: side effects of drugs, poisons, and food.

    abstract::A number of therapeutic agents, foods, chemicals, and poisons have been associated with the development or exacerbation of hypertension. This review discusses those identified in recent years. ...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Oren S,Grossman E,Messerli FH,Frohlich ED

    更新日期:1988-11-01 00:00:00

  • Total artificial heart: destination therapy.

    abstract::The AbioCor is a revolutionary device. It is the only device of its kind in the clinical world. The role of the AbioCor is to provide permanent replacement of the failing heart for patients who are not transplant candidates. The clinical trial has been successful in the majority (four of seven) of patients implanted t...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8651(02)00141-8

    authors: Samuels LE,Dowling R

    更新日期:2003-02-01 00:00:00

  • New theories. Causes of dilated cardiomyopathy.

    abstract::Dilated cardiomyopathy is a heterogeneous disease, both clinically and genetically. Two genes responsible for X-linked DCM have been identified. Five genetic loci responsible for X-linked DCM have been identified. Five genetic loci responsible for autosomal dominant DCM have also been mapped but no genes identified so...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8651(05)70037-0

    authors: Bachinski LL,Roberts R

    更新日期:1998-11-01 00:00:00

  • Renal considerations in cardiovascular drug therapy.

    abstract::The increasing number of patients with both cardiac and renal disease makes it important for the clinician to bear in mind the effect of both renal failure and peritoneal or hemodialysis on the handling of drugs. Guidelines are available for specific medications; however, they must be used in the light of the patient'...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Feinfeld DA,Frishman WH

    更新日期:1987-11-01 00:00:00

  • Contemporary treatment of venous thromboembolic disease.

    abstract::Venous thromboembolism (VTE) is a potentially fatal condition and includes deep vein thrombosis and pulmonary embolism. The novel oral anticoagulants, which include the direct thrombin and factor Xa inhibitors, have been shown to be safe and effective for the treatment of VTE. Additional interventions include thrombol...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccl.2014.09.007

    authors: Galanis T,Merli GJ

    更新日期:2015-02-01 00:00:00

  • Carcinoid Heart Disease: A Guide for Clinicians.

    abstract::Carcinoid heart disease is the collective term for all cardiac manifestations that develop in patients with carcinoid. The cardiac manifestations of carcinoid tumors are attributed to the paraneoplastic effects of vasoactive substances released by the malignant cells. The clinical manifestations of carcinoid heart dis...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccl.2019.07.014

    authors: Perry D,Hayek SS

    更新日期:2019-11-01 00:00:00

  • Exercise as hypertension therapy.

    abstract::In conclusion, the findings of most recent studies show that moderate-intensity aerobic exercise training can lower BP in patients with stage 1 and 2 essential hypertension. The average reduction in BP is 10.5 mm Hg for systolic and 7.6 mm Hg for diastolic BP. The reductions do not appear to be gender- or age-specific...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8651(05)70232-0

    authors: Kokkinos PF,Narayan P,Papademetriou V

    更新日期:2001-08-01 00:00:00

  • The role of exercise training in the therapy of hyperlipoproteinemia.

    abstract::Exercise therapy is a valid therapeutic modality in patients with hyperlipoproteinemia (HLP). In combination with appropriate dietary modification, it can be a powerful therapeutic tool and may allow a reduction in hyperlipidemic medication doses. Improved triglyceride values and lipoprotein profiles can be obtained. ...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Superko HR,Haskell WH

    更新日期:1987-05-01 00:00:00

  • Valvular disease in the elderly.

    abstract::As the incidence of valvular disease in the elderly is increasing, understanding of its pathogenesis and natural progression as well as surgical approaches and device technologies are improving. Future studies are needed to develop medical interventions that slow or halt the degenerative valvular processes associated ...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8651(05)70061-8

    authors: Hinchman DA,Otto CM

    更新日期:1999-02-01 00:00:00

  • Historical aspects of electrocardiography.

    abstract::One hundred years ago, Augustus Desiré Waller recorded the human electrocardiogram for the first time, using a capillary electrometer. Electrocardiography only became clinically relevant in 1901 when Willem Einthoven devised his string galvanometer for this purpose. Sir Thomas Lewis was the key figure in showing the v...

    journal_title:Cardiology clinics

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Krikler DM

    更新日期:1987-08-01 00:00:00

  • Implantable hemodynamic monitors.

    abstract::The evaluation and management of volume status in patients with heart failure is a challenge for most clinicians. In addition, such an evaluation is possible only during a personal clinician-patient interface. The ability to acquire hemodynamic data continuously with the help of implanted devices with remote monitorin...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccl.2011.03.002

    authors: Tallaj JA,Singla I,Bourge RC

    更新日期:2011-05-01 00:00:00

  • Clinical pharmacology of antihypertensive drugs.

    abstract::Systemic hypertension is a major public health problem and is perhaps the most common chronic disorder in most societies. Most patients with vascular disease report hypertension in their medical history. Irrespective of the specialty that one practices, every physician will likely encounter patients with systemic hype...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8651(01)00008-x

    authors: Ram CV,Fenves A

    更新日期:2002-05-01 00:00:00

  • Biomarkers for diagnosis in thoracic aortic disease: CON.

    abstract::The fundamental requirements for a meaningful biomarker have not been met in the prediction of the aneurysm trait, the progression of the aneurysm disease state, or the prevention of catastrophic aortic complications. Aortic aneurysm is a worthy opponent on all fronts, and clinicians should continue actively to evalua...

    journal_title:Cardiology clinics

    pub_type: 评论,杂志文章,评审

    doi:10.1016/j.ccl.2010.01.018

    authors: Farkas EA

    更新日期:2010-05-01 00:00:00

  • Prognostic value of radionuclide exercise testing after myocardial infarction.

    abstract::Abnormal systolic ventricular function and persistent ischemia are sensitive indicators of poor prognosis following myocardial infarction. The use of exercise improves the utility of both radionuclide ventriculography and myocardial perfusion scintigraphy in the identification of postinfarction patients at high risk o...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Schocken DD

    更新日期:1984-08-01 00:00:00

  • Atrial Fibrillation and Stroke: Making Sense of Recent Observations on Anticoagulation.

    abstract::Atrial fibrillation (AF) is the most prevalent heart rhythm disorder. AF accounts for a great proportion of deaths because it independently increases all-cause mortality and cardiovascular mortality risks. Ischemic stroke is the most common cardiovascular adverse event in AF patients. Oral anticoagulation (OAC) therap...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccl.2015.12.006

    authors: Proietti M,Lip GY

    更新日期:2016-05-01 00:00:00

  • Pathogenesis and clinical physiology of hypertension.

    abstract::Significant advances have been made in understanding the pathogenesis and clinical physiology of primary hypertension. This article presents an overview of the physiology of normal blood pressure control and the pathophysiologic mechanisms that predispose individuals and populations to primary hypertension. The role o...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccl.2010.07.001

    authors: Singh M,Mensah GA,Bakris G

    更新日期:2010-11-01 00:00:00

  • Initial Clinical Evaluation.

    abstract::The initial evaluation of patients with transient loss of consciousness (LOC) comprises a detailed medical history, physical examination, and 12-lead electrocardiogram. Because there are many causes of syncopal and nonsyncopal LOC, an adequate method of taking the clinical history, which is the cornerstone of diagnosi...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccl.2015.04.002

    authors: Alboni P,Coppola P,Stucci N

    更新日期:2015-08-01 00:00:00

  • Interventional catheter procedures used in congenital heart disease.

    abstract::Many of the transcatheter devices described in this article remain investigational in the United States. Currently, we consider the applications of these techniques as either (1) procedures of choice (for closures of patent ductus arteriosus, balloon dilation or stent implantation for peripheral pulmonary stenoses, ba...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Landzberg MJ,Lock JE

    更新日期:1993-11-01 00:00:00

  • The influence of the site and locus of myocardial damage on prognosis.

    abstract::The overall management and prognosis of patients with acute myocardial infarction must take into account not only infarct size but also the site and locus of involvement as determined by electrocardiography. Transmural versus nontransmural infarction is discussed in relation to therapy and prognosis. ...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Roberts R,Pratt CM

    更新日期:1984-02-01 00:00:00

  • Pathophysiology of cardiovascular disease and renal failure.

    abstract::This article discusses the epidemiology of cardiovascular (CV) events in end-stage and early renal disease, summarizes the profile of classic and nonclassic CV risk factors in renal patients, highlights recent evidence documenting accelerated atherogenesis in renal disease, and provides information on the central arte...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccl.2005.03.002

    authors: Dikow R,Zeier M,Ritz E

    更新日期:2005-08-01 00:00:00

  • Evaluation of plaque morphology by coronary CT angiography.

    abstract::Coronary computed tomographic angiography (CTA) is a promising noninvasive tool that allows the visualization of plaque morphology. Plaques characterized by positive remodeling, low attenuation, and napkin ring circular enhancement on contrast-enhanced coronary CTA have been regarded as rupture-prone vulnerable plaque...

    journal_title:Cardiology clinics

    pub_type: 杂志文章

    doi:10.1016/j.ccl.2011.10.002

    authors: Fujimoto S,Kondo T,Narula J

    更新日期:2012-02-01 00:00:00

  • Normal and abnormal rhythms associated with dual-chamber pacemakers.

    abstract::Except for the unique eccentricities of individual devices, most dual-chamber paced rhythms, both normal and abnormal, are readily understood and lend themselves to analysis if the programmed parameters are known. Although they may appear intimidating, this need not be the case if the physician is initially willing to...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Levine PA

    更新日期:1985-11-01 00:00:00

  • Atrial Fibrillation Ablation Should Be First-line Therapy in Patients with Heart Failure Reduced Ejection Fraction.

    abstract::Catheter ablation for atrial fibrillation in patients with heart failure with reduced ejection fraction is associated with improvement in patient-centered outcomes, such as mortality, heart failure readmission, and atrial fibrillation recurrence, compared with standard medical therapy with or without device therapy. T...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccl.2019.01.004

    authors: Agasthi P,Tseng A,Lee JZ,Mulpuru SK

    更新日期:2019-05-01 00:00:00

  • Life-threatening cardiovascular consequences of anger in patients with coronary heart disease.

    abstract::Anger is the affective state most commonly associated with myocardial ischemia and life-threatening arrhythmias. The scope of the problem is sizeable-at least 36,000 (2.4% of 1.5 million) heart attacks are precipitated annually in the United States by anger. The lethal cardiovascular consequences in ischemic heart dis...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8651(05)70281-2

    authors: Verrier RL,Mittleman MA

    更新日期:1996-05-01 00:00:00

  • Surgical Myectomy: Subaortic, Midventricular, and Apical.

    abstract::Surgical septal myectomy is the preferred method of septal reduction for most patients with obstructive hypertrophic cardiomyopathy whose symptoms do not respond to medical management. Transaortic extended septal myectomy has low operative mortality and provides durable relief of symptoms. Surgical treatment is possib...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccl.2018.08.006

    authors: Nguyen A,Schaff HV

    更新日期:2019-02-01 00:00:00

  • Three-dimensional echocardiography: an alternative imaging choice for evaluation of tricuspid valve disorders.

    abstract::This article presents an approach to real-time three-dimensional imaging of the tricuspid valve from three different views. This is followed by some representative cases that illustrate these views and some unique tricuspid valve abnormalities, including one case of corrected transposition. ...

    journal_title:Cardiology clinics

    pub_type: 杂志文章

    doi:10.1016/j.ccl.2007.06.001

    authors: Ahlgrim AA,Nanda NC,Berther E,Gill EA

    更新日期:2007-05-01 00:00:00

  • Exercise testing in chest pain units: rationale, implementation, and results.

    abstract::Chest pain units are now established centers for assessment of low-risk patients presenting to the emergency department with symptoms suggestive of acute coronary syndrome. Accelerated diagnostic protocols, of which treadmill testing is a key component, have been developed within these units for efficient evaluation o...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccl.2005.08.016

    authors: Amsterdam EA,Kirk JD,Diercks DB,Lewis WR,Turnipseed SD

    更新日期:2005-11-01 00:00:00

  • Ebstein Anomaly in the Adult Patient.

    abstract::Ebstein anomaly is a congenital malformation involving primarily the tricuspid valve, with failure of delamination from the underlying myocardium and right ventricular myopathy. Echocardiography is diagnostic in most patients and demonstrates apical displacement of the septal leaflet and variable tethering of leaflet ...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccl.2020.04.004

    authors: Fuchs MM,Connolly HM

    更新日期:2020-08-01 00:00:00

  • Primary and secondary prevention strategy for cardiovascular disease in diabetes mellitus.

    abstract::The majority of individuals with diabetes die from cardiovascular disease (CVD) and related complications. The risk of CVD is 2 to 4 fold greater in diabetes and largely magnified by co-morbidities that aggregate along with it. Sufficient evidence-based data now exist to support multifactorial risk intervention with s...

    journal_title:Cardiology clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccl.2010.11.004

    authors: Srikanth S,Deedwania P

    更新日期:2011-02-01 00:00:00