Abstract:
:Venous thromboembolism (VTE) is a potentially fatal condition and includes deep vein thrombosis and pulmonary embolism. The novel oral anticoagulants, which include the direct thrombin and factor Xa inhibitors, have been shown to be safe and effective for the treatment of VTE. Additional interventions include thrombolysis and the use of inferior vena cava filters. The purpose of this article is to provide a contemporary review of the treatment of VTE.
journal_name
Cardiol Clinjournal_title
Cardiology clinicsauthors
Galanis T,Merli GJdoi
10.1016/j.ccl.2014.09.007subject
Has Abstractpub_date
2015-02-01 00:00:00pages
49-57issue
1eissn
0733-8651issn
1558-2264pii
S0733-8651(14)00094-0journal_volume
33pub_type
杂志文章,评审abstract::Magnetic resonance imaging is unique in its variety of applications for imaging the cardiovascular system. A thorough assessment of myocardial structure, function, and perfusion; assessment of coronary artery anatomy and flow; and spectroscopic evaluation of cardiac energetics can be readily performed by magnetic reso...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8651(05)70012-6
更新日期:1998-05-01 00:00:00
abstract::Transesophageal echocardiography (TEE) provides excellent delineation of ventricular function in the ambulatory and critical settings. Major indications include the acutely ill patient with suboptimal images with other techniques and the intraoperative assessment of patients undergoing cardiac surgery and of cardiac p...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8651(05)70174-0
更新日期:2000-11-01 00:00:00
abstract::One of the major drivers of change in the practice of cardiology is population change. This article discusses the current debate about epidemiologic transition paired with other ongoing transitions with direct relevance to cardiovascular conditions. Challenges specific to patterns of risk factors over time; readiness ...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ccl.2016.08.004
更新日期:2017-02-01 00:00:00
abstract::Chest pain units are now established centers for assessment of low-risk patients presenting to the emergency department with symptoms suggestive of acute coronary syndrome. Accelerated diagnostic protocols, of which treadmill testing is a key component, have been developed within these units for efficient evaluation o...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ccl.2005.08.016
更新日期:2005-11-01 00:00:00
abstract::Although the growing use of continuous-flow left ventricular assist devices (LVADs) has improved the survival and quality of life of patients with stage D heart failure, ischemic and hemorrhagic cerebrovascular accidents remain one of the most-feared complications of this therapy and a significant source of disability...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ccl.2018.06.007
更新日期:2018-11-01 00:00:00
abstract::In the past, much attention in imaging research was focused on the macroscopic morphology and patency of arteries. Only recently, research and clinical interest have shifted to the microcirculation and its impact on the long-term prognosis in patients with vascular diseases. This focus and newly developed therapeutic ...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8651(03)00110-3
更新日期:2003-11-01 00:00:00
abstract::Mechanical circulatory assistance is making the transition from an investigational technique to standard clinical practice, especially for post-cardiotomy shock. History, techniques, medications, complications, and results of mechanical assistance are reviewed. Promising trends for the future are presented. ...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:
更新日期:1988-08-01 00:00:00
abstract::Survivorship into adulthood of patients with congenital heart disease is due to improvements in prenatal detection, novel surgeries, and specialized adult congenital heart disease care. As patients survive further into adulthood, long-term complications of congenital and repaired physiology have been more clearly eluc...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ccl.2020.02.002
更新日期:2020-05-01 00:00:00
abstract::The number of supporters of complete arch replacement in the surgery of acute type A aortic dissection has been steadily increasing as a result of cerebral perfusion techniques that enable the extension of safe circulatory arrest time. However, there is no agreement in the surgical community on an optimal surgical app...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ccl.2010.01.007
更新日期:2010-05-01 00:00:00
abstract::In conclusion, the findings of most recent studies show that moderate-intensity aerobic exercise training can lower BP in patients with stage 1 and 2 essential hypertension. The average reduction in BP is 10.5 mm Hg for systolic and 7.6 mm Hg for diastolic BP. The reductions do not appear to be gender- or age-specific...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8651(05)70232-0
更新日期:2001-08-01 00:00:00
abstract::Sudden death, a major cause of mortality in the Western world, usually results from electrophysiologic phenomena in chronically damaged hearts with advanced coronary atherosclerosis. The exact pathophysiologic mechanisms are not known, but there is reasonable circumstantial evidence to implicate myocardial ischemia--c...
journal_title:Cardiology clinics
pub_type: 杂志文章
doi:
更新日期:1986-11-01 00:00:00
abstract::The indications for clinical electrophysiologic study have continued to evolve since the introduction of this technique in the mid 1960s. They now include evaluation of sinus node dysfunction, AV conduction disturbances, syncope of unknown etiology, supraventricular arrhythmias with and without Wolff-Parkinson-White s...
journal_title:Cardiology clinics
pub_type: 杂志文章
doi:
更新日期:1985-02-01 00:00:00
abstract::The physiology and hemodynamic functions of the right ventricle in normal and disease states differ considerably from those of the left ventricle. To illuminate these differences, the right ventricle's essential functions in the normal circulation are reviewed, its functional anatomy and blood supply are described, pr...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:
更新日期:1992-02-01 00:00:00
abstract::The goal of anticoagulant therapy in unstable angina is to prevent progression of a subocclusive coronary thrombus to complete occlusion of the coronary artery, thereby preventing myocardial infarction and death. Although these have been many advances in therapy with anticoagulants, considerable morbidity and mortalit...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8651(05)70078-3
更新日期:1999-05-01 00:00:00
abstract::Percutaneous transvenous balloon mitral valvuloplasty is a well-established alternative to surgical commissurotomy for selected symptomatic patients with rheumatic mitral stenosis. This procedure normally is performed with fluoroscopic guidance; however, even the experienced operator can be misled by radiographic land...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:
更新日期:1993-08-01 00:00:00
abstract::Chronic total coronary occlusions (CTOs) are a frequent finding in patients with coronary disease and remain one of the most challenging target lesion subsets for intervention. CTOs have been reported in approximately one-third of patients undergoing diagnostic coronary angiography. By nature of their complexity, CTO ...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ccl.2009.10.003
更新日期:2010-02-01 00:00:00
abstract::The initial evaluation of patients with transient loss of consciousness (LOC) comprises a detailed medical history, physical examination, and 12-lead electrocardiogram. Because there are many causes of syncopal and nonsyncopal LOC, an adequate method of taking the clinical history, which is the cornerstone of diagnosi...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ccl.2015.04.002
更新日期:2015-08-01 00:00:00
abstract::Many types of artificial sensors for adaptive-rate pacing have appeared but as yet there is no single sensor that properly reflects metabolic demand under all circumstances. Several other types of sensors are currently evaluated. Combinations of different sensors in a single unit are very promising. At present, howeve...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:
更新日期:1992-11-01 00:00:00
abstract::Quality of life is discussed with focus on the importance of individual patient perspectives. Eight studies including at least one aspect of quality of life in patients with atrial fibrillation are reviewed with three approaches evident in assessing quality of life: patient interview, self-reported symptoms, and multi...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8651(05)70307-6
更新日期:1996-11-01 00:00:00
abstract::Syncope is a common but complex medical disorder with a multitude of etiologies, some of which are still not well understood. In a general population, the greatest diagnostic yield is from the history and physical examination. Numerous other diagnostic modalities include Holter monitoring, signal-averaged ECG, cardiac...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:
更新日期:1991-11-01 00:00:00
abstract::The overall management and prognosis of patients with acute myocardial infarction must take into account not only infarct size but also the site and locus of involvement as determined by electrocardiography. Transmural versus nontransmural infarction is discussed in relation to therapy and prognosis. ...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:
更新日期:1984-02-01 00:00:00
abstract::Hypertrophic cardiomyopathy is a genetic heart disease with heterogeneous clinical features, including progression to advanced heart failure. The development of these symptoms can be related to outflow obstruction but in some patients reflects an underlying process of fibrosis and progressive ventricular dysfunction. ...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ccl.2018.08.007
更新日期:2019-02-01 00:00:00
abstract::Ischemic heart disease remains the leading cause of death worldwide. Low-density lipoprotein cholesterol (LDL-C) has proved to have a causal relationship with atherosclerotic cardiovascular disease. Lowering LDL-C improves outcomes, although some patients continue to have residual risk of cardiovascular disease. Cardi...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ccl.2017.12.002
更新日期:2018-05-01 00:00:00
abstract::This article discusses the epidemiology of cardiovascular (CV) events in end-stage and early renal disease, summarizes the profile of classic and nonclassic CV risk factors in renal patients, highlights recent evidence documenting accelerated atherogenesis in renal disease, and provides information on the central arte...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ccl.2005.03.002
更新日期:2005-08-01 00:00:00
abstract::Besides the anatomoclinical correlates of disturbances in impulse formation and conduction, this article also considers the three mechanisms now known to underlie tachyarrhythmias: focally enhanced automaticity, triggered activity, and, in particular, reentry. ...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:
更新日期:1983-02-01 00:00:00
abstract::Cardiac transplantation is now an accepted therapeutic procedure in the management of patients suffering from end-stage congestive heart failure. The advances in myocardial preservation, long-distance procurement, immunosuppression, improvement in the treatment of infectious diseases, and utilization of endomyocardial...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:
更新日期:1989-02-01 00:00:00
abstract::Although direct angioplasty may have been undervalued in the past, its utility in the treatment of acute coronary occlusion is now firmly established, and it unquestionably will remain an integral component of myocardial reperfusion therapy. As refinements in angioplasty equipment, cardiovascular support techniques, a...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:
更新日期:1995-08-01 00:00:00
abstract::The cardiologist and internist can make a major contribution to the care of patients with neurologic disease, both in terms of treating patients with symptomatic cardiac involvement and reducing mortality. This article highlights the need to recognize ECG abnormalities that may represent purely neurologic disease as w...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:
更新日期:1995-05-01 00:00:00
abstract::Despite tremendous progress made in the management of CHD, a significant number of fatal and nonfatal CHD events still occur, which leads researchers to target other modifiable risk factors for CHD including low HDL-c (high density lipoprotein cholesterol). Although the torcetrapib experience was a major blow to CETP ...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ccl.2008.06.005
更新日期:2008-11-01 00:00:00
abstract::The treatment of cardiorenal syndrome is as complex as the various mechanisms underlying its pathophysiology. Randomized controlled data typically focus on the treatment of heart failure with cardiac specific endpoints and a lack of worsening renal function used as a surrogate for efficacy. When heart failure is consi...
journal_title:Cardiology clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ccl.2019.04.002
更新日期:2019-08-01 00:00:00