Treatment of Cardiorenal Syndrome.

Abstract:

:The treatment of cardiorenal syndrome is as complex as the various mechanisms underlying its pathophysiology. Randomized controlled data typically focus on the treatment of heart failure with cardiac specific endpoints and a lack of worsening renal function used as a surrogate for efficacy. When heart failure is considered the inciting event, the acute state is managed with vasodilators, inotropic support, and decongestion; whereas neurohormonal axis inhibition is more commonly applied to chronic state. A recent shift in thought process regarding the interplay of cardiac and renal dysfunction suggests that renal congestion may be the primary driver of worsening renal function.

journal_name

Cardiol Clin

journal_title

Cardiology clinics

authors

Rubinstein J,Sanford D

doi

10.1016/j.ccl.2019.04.002

subject

Has Abstract

pub_date

2019-08-01 00:00:00

pages

267-273

issue

3

eissn

0733-8651

issn

1558-2264

pii

S0733-8651(19)30028-1

journal_volume

37

pub_type

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