当前位置： SCI文献检索 > ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY期刊下所有文献 > Reproductive consequences of exposure to waterborne phytoestrogens in male fighting fish Betta splendens.

Reproductive consequences of exposure to waterborne phytoestrogens in male fighting fish Betta splendens.

Abstract：

:Phytoestrogens are plant compounds that can act as endocrine disruptors in vertebrates. Biologically active levels of phytoestrogens have been found in aquatic habitats near wood pulp and paper mills, biofuel manufacturing plants, sewage-treatment plants, and agricultural fields. Phytoestrogens are known to cause hormonal and gonadal changes in male fish, but few studies have connected these effects to outcomes relevant to reproductive success. In one experiment, we exposed sexually mature male fighting fish Betta splendens to environmentally relevant (1 μg L(-1)) and pharmacological concentrations (1000 μg L(-1)) of the phytoestrogen genistein as well as to a positive control of waterborne 17β-estradiol (E2; 1 μg L(-1)), and a negative control of untreated water. In a second experiment, we exposed male B. splendens to environmentally relevant concentrations (1 μg L(-1)) of genistein and β-sitosterol singly and in combination as well as to the positive and negative controls. All exposures were 21 days in duration. We measured sex-steroid hormone levels, gonadosomatic index (GSI), sperm concentration and motility, and fertilization success in these fish. We found that exposure to genistein did not affect circulating levels of the androgen 11-ketotestosterone or the estrogen E2 relative to negative-control fish. We also found that neither of the compounds nor their mixture affected GSI, sperm concentration or motility, or fertilization success in exposed fish relative to negative-control fish. However, fish exposed to phytoestrogens showed some evidence of fewer but more motile sperm than fish exposed to the positive control E2. We conclude that sexually mature male B. splendens are relatively immune to reproductive impairments from short-term exposure to waterborne phytoestrogens.

journal_name

Arch Environ Contam Toxicol

journal_title

Archives of environmental contamination and toxicology

authors

Stevenson LM,Brown AC,Montgomery TM,Clotfelter ED

doi

10.1007/s00244-010-9561-y

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

501-10

issue

eissn

0090-4341

issn

1432-0703

journal_volume

pub_type

杂志文章

在线工具

Reproductive consequences of exposure to waterborne phytoestrogens in male fighting fish Betta splendens.